Omeros Corporation
US ˙ NasdaqGM ˙ US6821431029

SecurityOMER / Omeros Corporation
InstitutionIngalls & Snyder Llc
Latest Disclosed Ownership3,466,268 shares
Ownership 4.80%
Ingalls & Snyder Llc ownership in OMER / Omeros Corporation

2026-04-23 - Ingalls & Snyder Llc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 3,466,268 shares of Omeros Corporation (US:OMER). This represents 4.8 percent ownership of the company. In their previous filing dated 2025-02-21 , Ingalls & Snyder Llc had reported owning 4,161,315 shares, indicating a decrease of -16.70 percent.

Ingalls & Snyder Llc has a history of taking positions in derivatives of the underlying security (OMER) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2026-04-23 2026-04-23 13G/A 4,161,315 3,466,268 -16.70 4.80 -33.33
2025-02-21 2025-02-21 13G/A 4,431,188 4,161,315 -6.09 7.20 2.86
2024-03-27 2024-03-27 13G/A 4,131,793 4,431,188 7.25 7.00 6.06
2023-02-17 2023-02-17 13G/A 4,464,492 4,131,793 -7.45 6.60 -7.04
2022-02-04 2022-02-04 13G/A 4,748,189 4,464,492 -5.97 7.10 -7.79
2021-02-09 2021-02-09 13G/A 5,030,671 4,748,189 -5.62 7.70 -18.00
2020-02-07 2020-02-07 13G/A 5,582,273 5,030,671 -9.88 9.39 -17.63
2019-01-30 2019-01-30 13G/A 5,714,180 5,582,273 -2.31 11.40 -4.20
2018-02-09 2018-02-09 13G/A 5,097,510 5,714,180 12.10 11.90 0.25
2017-02-14 2017-02-14 13G/A 3,760,620 5,097,510 35.55 11.87 19.90
2016-02-05 2016-02-05 13G/A 3,760,620 9.90
2015-02-06 2015-02-06 13G/A 2,347,987 6.90
2014-04-01 2014-04-01 13G/A 1,717,860 5.10
2013-07-11 2013-07-11 13G/A 1,293,985 4.30
2013-04-11 2013-04-11 13G 1,322,885 5.10

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Institutional Put/Call Ratios
(Premium Subscription Required)

In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

OMER / Omeros Corporation Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F OMEROS COM 682143102 3,559,423 110,724 3.21 38 -37.29 1.3304
2026-02-13 2025-12-31 13F OMEROS COM 682143102 3,448,699 -657,899 -16.02 59 268.75 2.1750
2025-11-07 2025-09-30 13F OMEROS COM 682143102 4,106,598 123,685 3.11 17 45.45 0.5505
2025-07-31 2025-06-30 13F OMEROS COM 682143102 3,982,913 5,100 0.13 12 -65.62 0.4239
2025-05-12 2025-03-31 13F OMEROS COM 682143102 3,977,813 -30,055 -0.75 33 -17.95 1.0754
2025-01-29 2024-12-31 13F OMEROS COM 682143102 4,007,868 -531,547 -11.71 40 116.67 1.5529
2024-11-14 2024-09-30 13F OMEROS COM 682143102 4,539,415 -53,733 -1.17 18 0.00 0.7032
2024-07-31 2024-06-30 13F OMEROS COM 682143102 4,593,148 -104,992 -2.23 19 12.50 0.8017
2024-05-13 2024-03-31 13F OMEROS COM 682143102 4,698,140 151,378 3.33 16 14.29 0.7157
2024-01-29 2023-12-31 13F OMEROS COM 682143102 4,546,762 -96,824 -2.09 15 7.69 0.6722
2023-11-02 2023-09-30 13F OMEROS COM 682143102 4,643,586 -12,675 -0.27 14 -48.00 0.6527
2023-07-27 2023-06-30 13F OMEROS COM 682143102 4,656,261 -7,280 -0.16 25 19.05 1.2130
2023-05-09 2023-03-31 13F OMEROS COM 682143102 4,663,541 976,800 26.49 22 162.50 1.1141
2023-01-31 2022-12-31 13F OMEROS COM 682143102 3,686,741 -404,863 -9.89 8 -99.94 0.4531
2022-10-21 2022-09-30 13F OMEROS COM 682143102 4,091,604 -59,158 -1.43 12,889 12.91 0.7194
2022-08-11 2022-06-30 13F OMEROS COM 682143102 4,150,762 -54,328 -1.29 11,415 -54.83 0.5966
2022-05-09 2022-03-31 13F OMEROS COM 682143102 4,205,090 -118,137 -2.73 25,273 -9.08 1.1287
2022-02-11 2021-12-31 13F OMEROS COM 682143102 4,323,227 -139,290 -3.12 27,798 -54.83 1.2535
2021-10-27 2021-09-30 13F OMEROS COM 682143102 4,462,517 -7,050 -0.16 61,538 -7.22 2.8181
2021-08-03 2021-06-30 13F OMEROS COM 682143102 4,469,567 149,775 3.47 66,328 -13.74 2.9456
2021-04-21 2021-03-31 13F OMEROS CO 682143102 4,319,792 -46,431 -1.06 76,892 23.28 3.5897
2021-01-27 2020-12-31 13F OMEROS COM 682143102 4,366,223 -46,705 -1.06 62,371 39.87 3.0792
2020-10-21 2020-09-30 13F OMEROS COM 682143102 4,412,928 -24,640 -0.56 44,593 -31.73 3.0601
2020-07-31 2020-06-30 13F OMEROS COM 682143102 4,437,568 -198,737 -4.29 65,321 5.38 3.7518
2020-04-22 2020-03-31 13F OMEROS COM 682143102 4,636,305 -14,300 -0.31 61,987 -5.40 4.1772
2020-01-15 2019-12-31 13F OMEROS COM 682143102 4,650,605 -373,150 -7.43 65,527 -20.13 3.5474
2019-10-16 2019-09-30 13F OMEROS COM 682143102 5,023,755 58,198 1.17 82,038 5.30 4.0035
2019-07-11 2019-06-30 13F OMEROS COM 682143102 4,965,557 -111,700 -2.20 77,910 -11.66 3.7470
2019-04-11 2019-03-31 13F OMEROS COM 682143102 5,077,257 -93,150 -1.80 88,192 53.12 4.2021
2019-01-24 2018-12-31 13F OMEROS COM 682143102 5,170,407 -92,530 -1.76 57,598 -55.17 3.0408
2018-10-24 2018-09-30 13F OMEROS COM 682143102 5,262,937 -350,550 -6.24 128,468 26.16 5.4138
2018-08-10 2018-06-30 13F OMEROS COM 682143102 5,613,487 70,625 1.27 101,829 64.47 4.7259
2018-04-17 2018-03-31 13F OMEROS COM 682143102 5,542,862 207,623 3.89 61,914 -40.27 3.0197
2018-01-19 2017-12-31 13F OMEROS COM 682143102 5,335,239 174,204 3.38 103,664 -7.10 4.7707
2017-10-20 2017-09-30 13F OMEROS COM 682143102 5,161,035 17,746 0.35 111,582 8.99 5.8120
2017-07-28 2017-06-30 13F OMEROS COM 682143102 5,143,289 50,970 1.00 102,377 32.96 5.5584
2017-05-09 2017-03-31 13F OMEROS COM 682143102 5,092,319 -36,950 -0.72 76,996 51.32 4.1070
2017-01-25 2016-12-31 13F OMEROS COM 682143102 5,129,269 43,320 0.85 50,882 -10.35 2.7705
2016-11-03 2016-09-30 13F OMEROS COM 682143102 5,085,949 671,370 15.21 56,759 22.22 3.1651
2016-08-11 2016-06-30 13F OMEROS COM 682143102 4,414,579 349,773 8.60 46,441 -25.52 2.7402
2016-04-29 2016-03-31 13F OMEROS COMMON 068214310 4,064,806 264,132 6.95 62,354 4.30 3.9648
2016-01-27 2015-12-31 13F OMEROS COMMON 068214310 3,800,674 45,643 1.22 59,784 45.27 3.8196
2015-10-27 2015-09-30 13F OMEROS COMMON 068214310 3,755,031 666,580 21.58 41,155 -25.93 2.6905
2015-07-10 2015-06-30 13F OMEROS COMMON 068214310 3,088,451 660,193 27.19 55,561 3.86 3.0653
2015-04-15 2015-03-31 13F OMEROS COMMON 068214310 2,428,258 2,428,258 53,494 2.9459
2015-01-28 2014-12-31 13F OMEROS COMMON 068214310 0 -2,414,704 -100.00 0 -100.00
2014-10-28 2014-09-30 13F OMEROS COMMON 068214310 2,414,704 348,425 16.86 30,715 -14.57 1.6524
2014-07-30 2014-06-30 13F OMEROS COMMON 068214310 2,066,279 298,390 16.88 35,953 68.49 1.7670
2014-05-02 2014-03-31 13F OMEROS COMMON 068214310 1,767,889 505,004 39.99 21,338 49.67 1.1436
2014-01-24 2013-12-31 13F OMEROS COMMON 068214310 1,262,885 -5,300 -0.42 14,257 15.31 0.7857
2013-11-12 2013-09-30 13F OMEROS COMMON 068214310 1,268,185 -124,600 -8.95 12,364 76.15 0.7392
2013-08-09 2013-06-30 13F/A-1 OMEROS COMMON 068214310 1,392,785 1,392,785 7,019 0.4471
2013-08-08 2013-06-30 13F OMEROS COMMON 068214310 1,231,385 6,206
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-02-13 2025-12-31 13F OMEROS Call Call 0 -100.00 0 n/a n/a n/a
2025-11-07 2025-09-30 13F OMEROS Call Call 43,000 0 n/a n/a n/a
2024-05-13 2024-03-31 13F OMEROS Call Call 0 -100.00 0 n/a n/a n/a
2024-01-29 2023-12-31 13F OMEROS Call Call 10,000 -66.67 0 n/a n/a n/a
2023-11-02 2023-09-30 13F OMEROS Call Call 30,000 0 n/a n/a n/a
2023-07-27 2023-06-30 13F OMEROS Call Call 0 -100.00 0 n/a n/a n/a
2023-05-09 2023-03-31 13F OMEROS Call Call 2,500 0 n/a n/a n/a
2022-05-09 2022-03-31 13F OMEROS Call Call 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-11 2021-12-31 13F OMEROS Call Call 18,100 116 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.