Aquestive Therapeutics, Inc.
US ˙ NasdaqGM ˙ US03843E1047

SecurityAQST / Aquestive Therapeutics, Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership18,149 shares
Latest Disclosed Value $ 75,318
D. E. Shaw & Co., Inc. reports 98.07% decrease in ownership of AQST / Aquestive Therapeutics, Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 18,149 shares of Aquestive Therapeutics, Inc. (US:AQST) valued at $75,318 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 941,197 shares of Aquestive Therapeutics, Inc.. This represents a change in shares of -98.07% during the quarter. The current value of the position is $73,140 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 18,149 -923,048 -98.07 75 -98.77 0.0000
2026-02-17 2025-12-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 941,197 915,697 3,590.97 6,080 4,181.69 0.0033
2025-11-14 2025-09-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 25,500 -39,176 -60.57 143 -33.64 0.0001
2025-08-14 2025-06-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 64,676 -114,359 -63.88 214 -58.77 0.0002
2025-05-15 2025-03-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 179,035 52,571 41.57 519 15.33 0.0005
2025-02-14 2024-12-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 126,464 95,418 307.34 450 192.21 0.0003
2024-11-14 2024-09-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 31,046 20,858 204.73 155 492.31 0.0001
2024-08-14 2024-06-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 10,188 -85,025 -89.30 26 -93.58 0.0000
2024-05-15 2024-03-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 95,213 95,213 406 0.0003
2022-11-14 2022-09-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 0 -164,607 -100.00 0 -100.00
2022-08-15 2022-06-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 164,607 55,769 51.24 106 -62.68 0.0001
2022-05-16 2022-03-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 108,838 21,052 23.98 284 -16.72 0.0003
2022-02-14 2021-12-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 87,786 87,786 341 0.0003
2020-11-16 2020-09-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 0 -283,418 -100.00 0 -100.00
2020-08-14 2020-06-30 13F AQUESTIVE THERAPEUTICS COM 03843E104 283,418 69,196 32.30 1,378 193.82 0.0016
2020-05-15 2020-03-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 214,222 -49,195 -18.68 469 -69.41 0.0007
2020-02-14 2019-12-31 13F AQUESTIVE THERAPEUTICS COM 03843E104 263,417 263,417 1,533 0.0018
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.