Bicycle Therapeutics plc - Depositary Receipt (Common Stock)
DE ˙ DB ˙ US0887861088
3,56 € ↓ -0,04 (-1,11%)
2026-06-04
DEL PRIS
SecurityDE:50BA / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)
InstitutionMillennium Management Llc
ManagerIsrael Englander
Latest Disclosed Ownership283,986 shares
Latest Disclosed Value $ 1,317,695
Millennium Management Llc reports 13.05% decrease in ownership of 50BA / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)

On May 15, 2026 - Millennium Management Llc filed a 13F-HR form disclosing ownership of 283,986 shares of Bicycle Therapeutics plc - Depositary Receipt (Common Stock) (DE:50BA) valued at $1,050,748 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 326,626 shares of Bicycle Therapeutics plc - Depositary Receipt (Common Stock). This represents a change in shares of -13.05% during the quarter. The current value of the position is $1,010,990 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 283,986 -42,640 -13.05 1,318 -43.04 0.0005
2026-02-17 2025-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 326,626 -728,120 -69.03 2,313 -71.68 0.0010
2025-11-14 2025-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,054,746 -388,873 -26.94 8,164 -18.64 0.0035
2025-08-14 2025-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,443,619 990,191 218.38 10,033 160.67 0.0048
2025-05-15 2025-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 453,428 276,671 156.53 3,850 55.58 0.0020
2025-02-14 2024-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 176,757 176,757 2,475 0.0012
2024-11-14 2024-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 0 -37,507 -100.00 0 -100.00
2024-08-14 2024-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 37,507 37,507 759 0.0004
2024-05-15 2024-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 0 -249,135 -100.00 0 -100.00
2024-02-14 2023-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 249,135 -65,958 -20.93 4,504 -28.85 0.0019
2023-11-14 2023-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 315,093 236,334 300.07 6,330 215.08 0.0032
2023-08-14 2023-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 78,759 61,923 367.80 2,010 461.17 0.0010
2023-05-15 2023-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 16,836 -151,887 -90.02 358 -92.83 0.0002
2023-02-14 2022-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 168,723 25,677 17.95 4,994 50.11 0.0028
2022-11-14 2022-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 143,046 -190,655 -57.13 3,327 -40.59 0.0020
2022-08-15 2022-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 333,701 170,334 104.26 5,600 -21.89 0.0035
2022-05-16 2022-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 163,367 10,635 6.96 7,169 -22.89 0.0038
2022-02-14 2021-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 152,732 152,732 9,297 0.0047
2021-11-15 2021-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 0 -20,363 -100.00 0 -100.00
2021-08-16 2021-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 20,363 20,363 618 0.0004
2021-05-17 2021-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 0 -14,442 -100.00 0 -100.00
2021-02-16 2020-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 14,442 961 7.13 259 0.78 0.0002
2020-11-16 2020-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 13,481 -4,833 -26.39 257 -9.51 0.0003
2020-08-14 2020-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 18,314 3,073 20.16 284 24.56 0.0004
2020-05-14 2020-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 15,241 -5,949 -28.07 228 14.00 0.0005
2020-02-14 2019-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 21,190 -13,579 -39.05 200 -49.49 0.0003
2019-11-14 2019-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 34,769 -18,591 -34.84 396 -26.26 0.0006
2019-08-15 2019-06-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 53,360 53,360 537 0.0008
2019-08-14 2019-06-30 13F FIVERR INTL ORD SHS 088786108 147,595 4,384 0.0066
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.