| Insideraktier | 10.007.540 shares |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Netto antal insidere, der køber (rang)
N/A
Netto antal insidere, der køber, er det samlede antal insiders, der køber minus det samlede antal insiders, der har solgt inden for de sidste 90 dage. Percentilrangen vises her (spænder fra 0 til 100%).
Procent af float købt af insidere (rangering)
N/A
Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.
Insiderhandelsdiagram
Alpine Immune Sciences, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i ALPN / Alpine Immune Sciences, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i ALPN / Alpine Immune Sciences, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-05-20 | 2024-05-20 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | -1.900 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | -50.000 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | -2.829.347 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -264.315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -2.416.181 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -1.735.544 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -6.582.380 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -31.200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -26.761 | 31.200 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -48.000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -296.163 | 48.000 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -96.000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -13.245 | 96.000 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -2.627.157 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -7.300 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -22.820 | 7.300 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -31.200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -102.192 | 31.200 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -264.315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -2.416.181 | 0 | ||||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,3300 | 13.377 | 85 | 344.163 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 3,2300 | 26.912 | 87 | 330.786 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 11,3100 | 22.593 | 256 | 303.874 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 161.492 | 105 | 281.281 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 37.267 | 24 | 119.789 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,5100 | 3.126 | 20 | 82.522 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 13,2000 | 7.025 | 93 | 79.396 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,7600 | 10.000 | 48 | 133.392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 3,2300 | 38.078 | 123 | 123.392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,0900 | 12.365 | 51 | 85.314 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 6,5100 | 25.000 | 163 | 72.949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 13,2000 | 9.845 | 130 | 47.949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 7,5500 | 13.245 | 100 | 109.245 | ||||
| 2024-05-10 | 2024-05-08 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 12,0700 | 22.820 | 275 | 30.120 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 398 | 2 | 57.961 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 18.286 | 59 | 57.563 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 164 | 2 | 39.277 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 857 | 6 | 39.113 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,2000 | 7.055 | 93 | 38.256 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 7,5500 | 1 | 0 | 31.201 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 64,5700 | -19 | -1 | 2.829.347 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 0,0010 | 1.200.000 | 1 | 2.829.366 | ||||
| 2024-04-05 | 3 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 7.300 | ||||||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 25,0000 | -44.000 | -1.100 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 44.000 | 498 | 44.000 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,3121 | -73.764 | -1.646 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 73.764 | 480 | 73.764 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,0000 | -236 | -5 | 0 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 236 | 2 | 236 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 12,7400 | 1.234.636 | 15.729 | 6.582.380 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,7400 | 1.234.636 | 15.729 | 6.582.380 | ||||
| 2024-01-16 | 2024-01-11 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 2.416.181 | ||||
| 2024-01-16 | 2024-01-11 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 2.416.181 | ||||
| 2024-01-05 | 2024-01-04 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 48.000 | 72.371 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 96.000 | 96.000 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 31.200 | 31.200 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | DURAND REMY | ALPN | Common Stock | D | 31.200 | 38.104 | ||||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 19,6500 | -48.264 | -948 | 2.627.157 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 12,7400 | 74.441 | 948 | 2.675.421 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0413 | -1.016 | -20 | 0 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 1.016 | 1 | 1.016 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | -139.166 | -2.550 | 264.315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | -1.195.683 | -21.905 | 2.270.930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | -3.128 | -62 | 403.481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | -26.872 | -533 | 3.466.613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | -18.922 | -378 | 406.609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | -162.576 | -3.245 | 3.493.485 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | -139.166 | -2.550 | 264.315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | -1.195.683 | -21.905 | 2.270.930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | -3.128 | -62 | 403.481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | -26.872 | -533 | 3.466.613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | -18.922 | -378 | 406.609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | -162.576 | -3.245 | 3.493.485 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0425 | -29.573 | -593 | 0 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 29.573 | 19 | 29.573 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,2245 | -24.486 | -495 | 0 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 22.084 | 14 | 24.486 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2.402 | 1 | 2.402 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,4255 | -37.825 | -773 | 0 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 37.825 | 17 | 37.825 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,2087 | -15.213 | -292 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 15.213 | 76 | 15.213 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0099 | -2.402 | -48 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2.402 | 1 | 2.402 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0017 | -1.800 | -34 | 0 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 1.800 | 9 | 1.800 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0888 | -45.387 | -866 | 0 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 45.387 | 228 | 45.387 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0005 | -11.600 | -220 | 0 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 11.600 | 58 | 11.600 | ||||
| 2023-12-13 | 2023-12-11 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 1.629.366 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | -8.613 | -149 | 0 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 8.613 | 4 | 8.613 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | -32.450 | -562 | 0 | ||||
| 2023-12-12 | 2023-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,2648 | -68.870 | -1.189 | 32.450 | ||||
| 2023-12-12 | 2023-12-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,0799 | -8.067 | -138 | 101.320 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0797 | -6.446 | -104 | 0 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 6.446 | 21 | 6.446 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0139 | -418 | -7 | 0 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 418 | 1 | 418 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0584 | -63.947 | -1.027 | 0 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 63.947 | 207 | 63.947 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0000 | -700 | -11 | 0 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 700 | 2 | 700 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,5000 | 375.000 | 4.688 | 1.735.544 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Decheng Capital Global Healthcare Fund (Master), LP | ALPN | Common Stock | D | 12,5000 | 375.000 | 4.688 | 1.735.544 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0281 | -18.003 | -289 | 0 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 10.989 | 35 | 18.003 | ||||
| 2023-04-27 | 3 | DURAND REMY | ALPN | Common Stock | D | 6.904 | ||||||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 1.360.544 | 10.000 | 1.360.544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 639.456 | 4.700 | 5.347.744 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | I | 7,3500 | 1.360.544 | 10.000 | 1.360.544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 7,3500 | 639.456 | 4.700 | 5.347.744 | ||||
| 2022-07-19 | 2022-07-15 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 0,4500 | 20.063 | 9 | 238.126 | ||||
| 2022-02-15 | 2022-02-11 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 7,1006 | 112.665 | 800 | 1.484.115 | ||||
| 2022-01-06 | 2022-01-04 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,30 | 215.000 | 215.000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,30 | 215.000 | 215.000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,30 | 112.500 | 112.500 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2021-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,9162 | -17.013 | -237 | 7.014 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2021-09-27 | 2021-09-23 | 4/A | Peetz Christopher Christopher Peetz and Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1.900 | 19 | 1.900 | ||||
| 2021-09-27 | 2021-09-23 | 4/A | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15.000 | 151 | 50.000 | ||||
| 2021-09-24 | 2021-09-23 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1.900 | 19 | 1.900 | ||||
| 2021-09-24 | 2021-09-23 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15.000 | 151 | 50.000 | ||||
| 2021-09-23 | 2021-09-21 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 9,7966 | 10.000 | 98 | 35.000 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 425.531 | 4.000 | 425.531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 585.106 | 5.500 | 3.656.061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 9,4000 | 1.542.553 | 14.500 | 4.708.288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 425.531 | 4.000 | 425.531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 585.106 | 5.500 | 3.656.061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0076 | -45.262 | -453 | 109.387 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 9,4000 | 1.542.553 | 14.500 | 4.708.288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 0,00 | 1.200.000 | 1.200.000 | |||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | -1.200.000 | 1.371.450 | ||||||
| 2021-09-17 | 2021-09-16 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0024 | -6.768 | -68 | 154.649 | ||||
| 2021-09-17 | 2021-09-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0000 | -3.484 | -35 | 161.417 | ||||
| 2021-06-29 | 2021-06-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0005 | -3.479 | -35 | 164.901 | ||||
| 2021-06-29 | 2021-06-25 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0143 | -9.473 | -95 | 168.380 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Goldberg Zelanna | ALPN | Stock Option (Right to buy) | D | 10,29 | 160.000 | 160.000 | |||||
| 2021-05-21 | 2021-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0006 | -1.221 | -18 | 177.853 | ||||
| 2021-05-21 | 2021-05-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0283 | -50.965 | -766 | 179.074 | ||||
| 2021-05-14 | 2021-05-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,5169 | -10.000 | -115 | 230.039 | ||||
| 2021-05-14 | 2021-05-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,6842 | -10.000 | -117 | 240.039 | ||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | -7.650 | 0 | |||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 3,6233 | 7.650 | 28 | 218.063 | ||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | -7.650 | 0 | |||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 4,0900 | 7.650 | 31 | 210.413 | ||||
| 2021-04-15 | 2021-04-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,5200 | -10.000 | -105 | 250.039 | ||||
| 2021-04-15 | 2021-04-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0714 | -10.000 | -101 | 260.039 | ||||
| 2021-03-08 | 2021-03-05 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,9875 | -10.000 | -130 | 270.039 | ||||
| 2021-03-08 | 2021-03-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,0108 | -10.000 | -130 | 280.039 | ||||
| 2021-02-03 | 2021-02-02 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,7381 | -10.000 | -117 | 290.039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,2029 | -7.021 | -93 | 300.039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,0738 | -2.979 | -36 | 307.060 | ||||
| 2021-01-06 | 2021-01-05 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,20 | 150.000 | 150.000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,20 | 255.000 | 255.000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,20 | 120.000 | 120.000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-04 | 2020-12-31 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 12,6000 | -3.923 | -49 | 24.371 | ||||
| 2021-01-04 | 2020-12-31 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,6000 | -11.123 | -140 | 310.039 | ||||
| 2021-01-04 | 2020-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 12,6000 | -2.258 | -28 | 24.027 | ||||
| 2020-12-30 | 2020-12-28 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 14,2500 | -600.000 | -8.550 | 3.070.955 | ||||
| 2020-12-30 | 2020-12-28 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 14,2500 | -600.000 | -8.550 | 3.070.955 | ||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 260.528 | 321.162 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993.801 | 3.000.980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 181.024 | 202.763 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993.801 | 3.000.980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | -993.801 | 3.000.980 | ||||||
| 2020-12-11 | 2020-12-10 | 4 | Hernday Natasha | ALPN | Stock Option (right to buy) | D | 11,07 | 15.000 | 15.000 | |||||
| 2020-11-23 | 2020-11-19 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 8,0300 | 10.000 | 80 | 25.000 | ||||
| 2020-07-09 | 2020-07-08 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 7,20 | 50.000 | 50.000 | |||||
| 2020-07-01 | 2020-06-30 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 9,7100 | -3.923 | -38 | 28.294 | ||||
| 2020-07-01 | 2020-06-30 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 9,7100 | -8.227 | -80 | 60.634 | ||||
| 2020-07-01 | 2020-06-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 9,7100 | -2.258 | -22 | 26.285 | ||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 3,23 | 270.000 | 270.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 67.569 | 68.861 | ||||||
| 2020-01-27 | 2019-12-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5.000 | 1.292 | ||||||
| 2020-01-27 | 2019-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5.000 | 6.292 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 3,23 | 108.000 | 108.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 32.217 | 32.217 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 3,23 | 102.000 | 102.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Common Stock | D | 18.543 | 28.543 | ||||||
| 2020-01-06 | 2020-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 4,9500 | 10.000 | 50 | 10.000 | ||||
| 2019-02-12 | 2019-02-08 | 4 | TIGER MANAGEMENT L.L.C. | ALPN | Common Stock | I | 5,8498 | -25.000 | -146 | 137.728 | ||||
| 2019-02-08 | 2019-02-06 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 25.000 | 25.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 6,51 | 200.000 | 200.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Stock Option (right to buy) | D | 5,70 | 7.650 | 7.650 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Warrant (right to buy) | I | 12,74 | 5,3700 | 1.234.636 | 6.630 | 1.234.636 | |||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 5,3700 | 3.165.735 | 17.000 | 3.165.735 | ||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145.251 | 145.251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 3.670.955 | ||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145.251 | 145.251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 3.670.955 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2018-05-21 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -6.000 | 11.292 | ||||||
| 2019-01-22 | 2018-05-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3.000 | 17.292 | ||||||
| 2019-01-22 | 2018-05-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3.000 | 20.292 | ||||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | D | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | I | 12,74 | 145.251 | 145.251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 2.571.450 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 12,74 | 145.251 | 145.251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 5,3700 | 372.439 | 2.000 | 2.571.450 | ||||
| 2019-01-04 | 2019-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2018-10-02 | 2018-09-28 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 6,33 | 250.000 | 250.000 | |||||
| 2018-08-08 | 2018-08-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 150.000 | 150.000 | |||||
| 2018-04-24 | 2018-04-20 | 4 | Peetz Christopher | ALPN | Stock Option (right to buy) | D | 7,91 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 11,31 | 70.000 | 70.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 11,31 | 45.000 | 45.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 11,31 | 65.000 | 65.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 11,31 | 25.000 | 25.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 2017-07-24 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 3.298.516 | 3.298.516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 208.916 | 208.916 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 300.624 | 300.624 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 51.242 | 51.242 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3.803.906 | 3.803.906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 23.292 | 23.292 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Aidan J. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Simon P. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Noah M. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 90.063 | 90.063 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3.803.906 | 3.803.906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 21.739 | 21.739 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Nathaniel Graham Venkatesan | ALPN | Common Stock | I | 18.633 | 18.633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Reid Coleman Venkatesan | ALPN | Common Stock | I | 18.633 | 18.633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Rickey James Paul | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 74.535 | 74.535 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Topper James N See Footnotes | ALPN | Common Stock | I | 2.199.011 | 2.199.011 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 3.298.516 | 3.298.516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 37.267 | 37.267 | |||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 161.492 | 161.492 | |||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 1.715 | 4 | 201.811 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 6.359 | 14 | 717.089 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 9.732 | 22 | 1.109.258 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 3.673 | 8 | 200.096 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 13.046 | 30 | 710.730 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 20.181 | 46 | 1.099.526 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 3.920 | 9 | 196.423 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 12.624 | 29 | 697.684 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 19.206 | 44 | 1.079.345 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 2.727 | 6 | 192.503 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 10.023 | 23 | 685.060 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 15.350 | 34 | 1.060.139 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 1.805 | 4 | 189.776 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 6.903 | 16 | 675.037 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 10.192 | 23 | 1.044.789 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 1.124 | 3 | 187.971 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 4.223 | 10 | 668.134 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 6.253 | 14 | 1.034.597 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 2.909 | 7 | 186.847 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 10.541 | 24 | 663.911 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 16.436 | 38 | 1.028.344 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 5.510 | 13 | 183.938 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 6.897 | 16 | 653.370 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 24.965 | 57 | 1.011.908 | ||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 675 | 2 | 178.428 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 2.565 | 6 | 646.473 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 3.794 | 9 | 986.943 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 6.217 | 15 | 177.753 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 22.092 | 52 | 643.908 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 33.691 | 79 | 983.149 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 3.929 | 9 | 171.536 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 14.274 | 33 | 621.816 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 21.797 | 50 | 949.458 | ||||
| 2017-05-11 | 2017-05-08 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2800 | 15.000 | 34 | 60.000 | ||||
| 2017-05-10 | 2017-05-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3400 | 5.000 | 12 | 45.000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | TROHA JANICE | NVLS | Common Stock | D | 2,3400 | 10.000 | 23 | 10.000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3000 | 20.000 | 46 | 40.000 | ||||
| 2017-05-08 | 2017-05-04 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2600 | 10.000 | 23 | 20.000 | ||||
| 2017-01-23 | 2017-01-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200.000 | 200.000 | |||||
| 2017-01-23 | 2017-01-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200.000 | 200.000 | |||||
| 2017-01-05 | 2017-01-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 2,2700 | -6.687 | -15 | 11.368 | ||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.056 | 162.501 | |||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.055 | 18.055 | ||||||
| 2016-12-05 | 2016-12-02 | 4 | Carruthers R Michael | NVLS | Common Stock | D | 2,0940 | 24.000 | 50 | 24.000 | ||||
| 2016-10-05 | 2016-10-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 7,9600 | -5.820 | -46 | 12.236 | ||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.056 | 180.556 | |||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.056 | 18.056 | ||||||
| 2016-09-14 | 2016-09-12 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110.000 | 110.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | SEKHRI PAUL J | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Flynn James E Through Deerfield Management Company, L.P. | NVLS | Stock Option (right to buy) | I | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110.000 | 110.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 7,77 | 250.000 | 250.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Rodman David Malcom | NVLS | Stock Option (Right to Buy) | D | 7,77 | 100.000 | 100.000 | |||||
| 2016-07-06 | 2016-07-05 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 4,6600 | -5.950 | -28 | 12.105 | ||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.055 | 198.612 | |||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.055 | 18.055 | ||||||
| 2016-06-17 | 2016-06-16 | 4 | Congleton Jon | NVLS | Common Stock | D | 3,8689 | 5.000 | 19 | 20.000 | ||||
| 2016-03-25 | 2016-03-24 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,2169 | 5.000 | 21 | 15.000 | ||||
| 2016-03-23 | 2016-03-22 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,3815 | 5.000 | 22 | 10.000 | ||||
| 2015-12-14 | 2015-12-11 | 4 | Congleton Jon | NVLS | Common Stock | D | 8,1000 | 5.000 | 40 | 5.000 | ||||
| 2015-12-11 | 2015-12-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 8,1000 | 10.000 | 81 | 10.000 | ||||
| 2015-09-15 | 2015-09-11 | 4 | Shoemaker Steven | NVLS | Stock Option (Right to Buy) | D | 15,28 | 39.700 | 39.700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 15,28 | 55.400 | 55.400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Gabriel Sherif | NVLS | Stock Option (Right to Buy) | D | 15,28 | 24.700 | 24.700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 15,28 | 121.100 | 121.100 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 15,28 | 65.400 | 65.400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-07-20 | 2015-07-16 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 2 Preferred Stock | I | -936.839 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 2 Preferred Stock | I | -817.541 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 2 Preferred Stock | I | -85.962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -54.385 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -385.962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 1 Preferred Stock | I | -1.243.423 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 1 Preferred Stock | I | -1.085.085 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 1 Preferred Stock | I | -1.401.003 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -869.667 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -2.013.613 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 14,0000 | 77.539 | 1.086 | 832.216 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 14,0000 | 67.666 | 947 | 726.242 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 14,0000 | 104.795 | 1.467 | 1.124.740 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 324.278 | 754.677 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 282.984 | 658.576 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 29.755 | 647.152 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 18.825 | 402.062 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 133.597 | 1.019.945 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 430.399 | 430.399 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 375.592 | 375.592 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 484.944 | 617.397 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 301.027 | 383.237 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 696.993 | 886.348 | ||||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Series 2 Convertible Preferred Stock | I | 2,85 | -364.358 | 0 | |||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 14,0000 | 200.000 | 2.800 | 564.358 | ||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 364.358 | 364.358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -1.052.631 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Common stock | D | 364.358 | 364.358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -818.714 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 283.390 | 320.990 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7479 | 5.500 | 81 | 37.600 | ||||
| 2015-06-23 | 2015-06-19 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,6659 | 11.700 | 172 | 32.100 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Series 2 convertible preferred stock | D | 14,00 | -303.631 | 0 | |||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 303.631 | 4.251 | 329.780 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Series 1 convertible preferred stock | D | -2.200.404 | 0 | ||||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 761.649 | 1.557.228 | ||||||
| 2015-06-19 | 2015-06-18 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6.200 | 91 | 20.400 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6.700 | 99 | 14.200 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,0000 | 7.500 | 105 | 7.500 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 26.149 | 366 | 26.149 | ||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1.301.830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1.301.830 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1.591.158 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1.591.158 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66.558 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66.558 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
