| Insideraktier | 786.266.474 shares |
| Total Insiders | 41 |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Procent af float købt af insidere (rangering)
N/A
Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.
Insiderhandelsdiagram
Adaptimmune Therapeutics plc - Depositary Receipt (Common Stock) insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Lawrence M Alleva Director - [D] | 12.600 | 12.600 | |
| Rafael Amado President, R&D - [O] | 17.237 | 17.237 | |
|
M James Barrett
10% Owner -
|
82.978.668 | 82.978.668 | |
|
Peter J Barris
10% Owner -
|
12.000.000 | 12.000.000 | |
|
Forest Baskett
10% Owner -
|
19.500.000 | 19.500.000 | |
| Ali Behbahani Director - [D] | 0 | 0 | |
| William C JR Bertrand Chief Operating Officer - [O] | 986.352 | 986.352 | |
| Gwendolyn Knowlton Binder-Scholl Chief Technology Officer - [O] | 2.487 | 2.487 | |
| Joanna Elizabeth Brewer | 223.512 | ||
| Barbara Gayle Duncan | 144.000 | ||
|
EcoR1 Capital, LLC
10% Owner -
|
100.371.882 | 100.371.882 | |
|
Florence Anthony A. Jr.
10% Owner -
|
19.500.000 | 19.500.000 | |
| John Furey | 196.186 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Michael Garone | 0 | ||
| Samuel D Isaly Director - [D] | 6.149.377 | 6.149.377 | |
|
Patrick J Kerins
10% Owner -
|
82.978.668 | 82.978.668 | |
|
Krishna Kittu Kolluri
10% Owner -
|
118.538.000 | 118.538.000 | |
| Giles Francis Bertram Kerr | 124.000 | ||
| Jonathan Kenneth Charles Knowles Director - [D] | 7.208.768 | 7.208.768 | |
| Ian Michael Laing Director - [D] | 58.085.600 | 58.085.600 | |
| John Lunger Chief Patient Supply Officer - [O] | 7.510 | 7.510 | |
|
David M Mott
Director, 10% Owner -
[D]
|
19.500.000 | 19.500.000 | |
| Garry E Menzel Director - [D] | 75.056 | 75.056 | |
|
Nea 14 Gp, Ltd
10% Owner -
|
82.978.668 | 82.978.668 | |
|
NEA Partners 14, L.P.
10% Owner -
|
82.978.668 | 82.978.668 | |
|
New Enterprise Associates 14, L.P.
10% Owner -
|
82.978.668 | 82.978.668 | |
| James Noble Director - [D] | 0 | 0 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Elliot Norry Chief Medical Officer - [O] | 7.510 | 7.510 | |
| Orbimed Advisors Llc Director - [D] | 4.901.310 | 4.901.310 | |
| OrbiMed Capital GP V LLC Director - [D] | 4.901.310 | 4.901.310 | |
| Cintia Piccina Chief Commercial Officer - [O] | 18.421 | 18.421 | |
| Adrian Rawcliffe Chief Executive Officer, Director - [D] [O] | 44.327 | 44.327 | |
|
Scott D Sandell
10% Owner -
|
19.500.000 | 19.500.000 | |
| Charles Elliott Sigal Director - [D] | 314.100 | 314.100 | |
|
Sonsini Peter W.
10% Owner -
|
19.500.000 | 19.500.000 | |
| Helen Katrina Tayton-martin Chief Business Officer - [O] | 1.800.000 | 1.800.000 | |
| Thompson Peter A. Director - [D] | 4.901.310 | 4.901.310 | |
|
Ravi Viswanathan
10% Owner -
|
12.000.000 | 12.000.000 | |
|
Harry R Weller
10% Owner -
|
118.538.000 | 118.538.000 | |
| Gavin Wood Chief Financial Officer - [O] | 0 | 0 | |
| Tal Zvi Zaks | 144.000 |
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i ADAP / Adaptimmune Therapeutics plc - Depositary Receipt (Common Stock). Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i ADAP / Adaptimmune Therapeutics plc - Depositary Receipt (Common Stock). Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-09-03 | 2025-09-02 | 4 | Wood Gavin | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,0099 | -96.000 | -1 | 0 | ||||
| 2025-08-29 | 2025-08-28 | 4 | Bertrand William C JR | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,0101 | -207.000 | -2 | 986.352 | ||||
| 2025-08-19 | 2025-08-18 | 4 | Behbahani Ali See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,0120 | -14.671.794 | -176 | 0 | ||||
| 2025-08-19 | 2025-08-15 | 4 | Behbahani Ali See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,0110 | -4.828.206 | -53 | 14.671.794 | ||||
| 2025-07-30 | 2025-07-30 | 4 | EcoR1 Capital, LLC See Note | ADAP | Ordinary Shares | I | 0,1021 | -27.433.338 | -2.801 | 100.371.882 | ||||
| 2025-07-30 | 2025-07-29 | 4 | EcoR1 Capital, LLC See Note | ADAP | Ordinary Shares | I | 0,1012 | -2.687.460 | -272 | 127.805.220 | ||||
| 2025-07-30 | 2025-07-28 | 4 | EcoR1 Capital, LLC See Note | ADAP | Ordinary Shares | I | 0,1125 | -33.931.740 | -3.817 | 130.492.680 | ||||
| 2025-01-17 | 2025-01-17 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5808 | -5.584 | -3 | 7.510 | ||||
| 2025-01-17 | 2025-01-17 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5808 | -5.584 | -3 | 7.510 | ||||
| 2025-01-17 | 2025-01-17 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5808 | -5.584 | -3 | 7.510 | ||||
| 2025-01-17 | 2025-01-17 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5808 | -30.601 | -18 | 44.327 | ||||
| 2025-01-15 | 2025-01-15 | 4 | Piccina Cintia | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5748 | -12.991 | -7 | 18.421 | ||||
| 2025-01-15 | 2025-01-15 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5748 | -29.096 | -17 | 41.582 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -17.934 | -11 | 25.711 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -12.539 | -7 | 17.801 | ||||
| 2025-01-15 | 2025-01-15 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5748 | -9.803 | -6 | 13.756 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -8.124 | -5 | 11.516 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -4.268 | -3 | 5.845 | ||||
| 2025-01-15 | 2025-01-15 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5748 | -9.803 | -6 | 13.756 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -5.471 | -3 | 7.623 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -4.268 | -3 | 5.845 | ||||
| 2025-01-15 | 2025-01-15 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5748 | -9.803 | -6 | 13.756 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -5.471 | -3 | 7.623 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,5879 | -4.268 | -3 | 5.845 | ||||
| 2024-06-18 | 2024-06-18 | 4 | Piccina Cintia | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,9300 | -24.531 | -23 | 38.293 | ||||
| 2024-03-26 | 3 | EcoR1 Capital, LLC See Note | ADAP | Ordinary Shares | I | 164.424.420 | ||||||||
| 2024-01-17 | 2024-01-17 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -30.080 | -20 | 44.848 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,7900 | -9.304 | -7 | 14.104 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -12.967 | -9 | 19.257 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -5.309 | -4 | 7.785 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,7900 | -2.287 | -2 | 3.363 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -12.805 | -9 | 19.015 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -5.309 | -4 | 7.785 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,7900 | -4.681 | -4 | 7.023 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -13.599 | -9 | 20.201 | ||||
| 2024-01-17 | 2024-01-17 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,6730 | -5.309 | -4 | 7.785 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,7900 | -4.681 | -4 | 7.023 | ||||
| 2024-01-12 | 2024-01-12 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8541 | -5.220 | -4 | 7.874 | ||||
| 2024-01-12 | 2024-01-11 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8367 | -4.009 | -3 | 6.104 | ||||
| 2024-01-12 | 2024-01-12 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8541 | -17.257 | -15 | 26.388 | ||||
| 2024-01-12 | 2024-01-11 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8367 | -11.945 | -10 | 18.395 | ||||
| 2024-01-12 | 2024-01-12 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8541 | -5.220 | -4 | 7.874 | ||||
| 2024-01-12 | 2024-01-11 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8367 | -4.009 | -3 | 6.104 | ||||
| 2024-01-12 | 2024-01-12 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8541 | -7.799 | -7 | 11.841 | ||||
| 2024-01-12 | 2024-01-11 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,8367 | -4.009 | -3 | 6.104 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,7800 | -2.403 | -2 | 3.449 | ||||
| 2023-08-01 | 2023-08-01 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,9056 | -3.096 | -3 | 4.718 | ||||
| 2023-07-10 | 2023-07-10 | 4 | Menzel Garry E | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,9108 | -47.702 | -43 | 75.056 | ||||
| 2023-06-27 | 2023-06-27 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 0,9200 | -2.333 | -2 | 3.519 | ||||
| 2023-06-01 | 2023-06-01 | 4 | Menzel Garry E | ADAP | American Depositary Shares representing Ordinary Shares | D | 209.931 | 209.931 | ||||||
| 2023-06-01 | 2023-06-01 | 4 | Menzel Garry E | ADAP | American Depositary Shares representing Ordinary Shares | I | 200.647 | 200.647 | ||||||
| 2023-06-01 | 2023-06-01 | 4 | Menzel Garry E | ADAP | American Depositary Shares representing Ordinary Shares | I | 200.646 | 200.646 | ||||||
| 2023-01-31 | 2023-01-31 | 4 | Piccina Cintia | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,8696 | -11.890 | -22 | 19.535 | ||||
| 2023-01-17 | 2023-01-17 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,8580 | -4.440 | -8 | 7.264 | ||||
| 2023-01-17 | 2023-01-17 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,8580 | -10.057 | -19 | 13.351 | ||||
| 2023-01-17 | 2023-01-17 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,8580 | -4.440 | -8 | 7.264 | ||||
| 2023-01-17 | 2023-01-17 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,8580 | -2.159 | -4 | 3.491 | ||||
| 2023-01-12 | 2023-01-12 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7060 | -4.973 | -8 | 8.121 | ||||
| 2023-01-12 | 2023-01-11 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7468 | -3.843 | -7 | 6.270 | ||||
| 2023-01-12 | 2023-01-12 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7060 | -4.973 | -8 | 8.121 | ||||
| 2023-01-12 | 2023-01-11 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7468 | -3.843 | -7 | 6.270 | ||||
| 2023-01-12 | 2023-01-12 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7060 | -7.449 | -13 | 12.191 | ||||
| 2023-01-12 | 2023-01-11 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7468 | -3.843 | -7 | 6.270 | ||||
| 2023-01-12 | 2023-01-12 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7060 | -18.763 | -32 | 24.882 | ||||
| 2023-01-12 | 2023-01-11 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7468 | -13.042 | -23 | 17.298 | ||||
| 2023-01-04 | 2023-01-04 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6940 | -3.584 | -6 | 5.781 | ||||
| 2023-01-04 | 2023-01-04 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6940 | -5.073 | -9 | 6.631 | ||||
| 2023-01-04 | 2023-01-04 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6940 | -876 | -1 | 1.361 | ||||
| 2023-01-04 | 2023-01-04 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6940 | -1.100 | -2 | 1.725 | ||||
| 2022-09-01 | 2022-09-01 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,9689 | -2.536 | -5 | 3.316 | ||||
| 2022-08-01 | 2022-08-01 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7735 | -2.983 | -5 | 4.829 | ||||
| 2022-08-01 | 2022-08-01 | 4 | Piccina Cintia | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,7735 | -21.040 | -37 | 34.824 | ||||
| 2022-07-05 | 2022-07-05 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6781 | -1.973 | -3 | 3.104 | ||||
| 2022-06-27 | 2022-06-27 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,6300 | -2.562 | -4 | 3.290 | ||||
| 2022-05-23 | 2022-05-20 | 4 | Wood Gavin | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,2904 | 39.000 | 11 | 96.000 | ||||
| 2022-05-04 | 2022-05-04 | 4 | Brewer Joanna Elizabeth | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 223.512 | 223.512 | |||||
| 2022-05-04 | 2022-05-04 | 4 | Brewer Joanna Elizabeth | ADAP | Option to purchase Ordinary Shares | D | 0,30 | 333.792 | 333.792 | |||||
| 2022-01-31 | 2022-01-31 | 4 | Piccina Cintia | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 335.184 | 335.184 | |||||
| 2022-01-31 | 2022-01-31 | 4 | Piccina Cintia | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 754.200 | 754.200 | |||||
| 2022-01-31 | 2022-01-31 | 4 | Piccina Cintia | ADAP | Option to purchase Ordinary Shares | D | 0,45 | 3.376.992 | 3.376.992 | |||||
| 2022-01-18 | 2022-01-18 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,1918 | -4.368 | -14 | 7.336 | ||||
| 2022-01-18 | 2022-01-18 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,1918 | -4.368 | -14 | 7.336 | ||||
| 2022-01-18 | 2022-01-18 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,1918 | -2.121 | -7 | 3.529 | ||||
| 2022-01-18 | 2022-01-18 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,1918 | -11.096 | -35 | 12.312 | ||||
| 2022-01-13 | 2022-01-12 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 314.256 | 314.256 | |||||
| 2022-01-13 | 2022-01-12 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 1.407.072 | 1.407.072 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 314.256 | 314.256 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 1.407.072 | 1.407.072 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5441 | -2.248 | -8 | 3.754 | ||||
| 2022-01-13 | 2022-01-11 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5567 | -3.770 | -13 | 6.343 | ||||
| 2022-01-13 | 2022-01-12 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 314.256 | 314.256 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 1.407.072 | 1.407.072 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5441 | -1.076 | -4 | 1.749 | ||||
| 2022-01-13 | 2022-01-11 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5567 | -3.770 | -13 | 6.343 | ||||
| 2022-01-13 | 2022-01-12 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5441 | -854 | -3 | 1.383 | ||||
| 2022-01-13 | 2022-01-11 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5567 | -3.770 | -13 | 6.343 | ||||
| 2022-01-13 | 2022-01-12 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5441 | -3.046 | -11 | 3.356 | ||||
| 2022-01-13 | 2022-01-11 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5567 | -14.362 | -51 | 15.978 | ||||
| 2022-01-13 | 2022-01-12 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 471.360 | 471.360 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 2.110.608 | 2.110.608 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 1.047.480 | 1.047.480 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 4.690.224 | 4.690.224 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 314.256 | 314.256 | |||||
| 2022-01-13 | 2022-01-12 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,60 | 1.407.072 | 1.407.072 | |||||
| 2022-01-05 | 2022-01-04 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,0642 | -3.490 | -14 | 5.873 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,0642 | -1.070 | -4 | 1.755 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,0642 | -849 | -3 | 1.388 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,0642 | -5.532 | -22 | 6.172 | ||||
| 2021-09-01 | 2021-09-01 | 4 | Rawcliffe Adrian | ADAP] | American Depositary Shares representing Ordinary Shares | D | 5,1950 | -2.782 | -14 | 3.070 | ||||
| 2021-08-02 | 2021-08-02 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 3,5848 | -2.939 | -11 | 4.873 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Duncan Barbara Gayle | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 379.788 | 379.788 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 505.918 | 505.918 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 474.385 | 474.385 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 474.385 | 474.385 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 379.788 | 379.788 | |||||
| 2021-07-02 | 2021-07-02 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,2649 | -4.375 | -19 | 7.329 | ||||
| 2021-07-02 | 2021-07-01 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 579.494 | 579.494 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 379.788 | 379.788 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Furey John | ADAP | Option to purchase Ordinary Shares | D | 0,71 | 379.788 | 379.788 | |||||
| 2021-07-02 | 2021-07-02 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,2649 | -1.907 | -8 | 3.170 | ||||
| 2021-06-28 | 2021-06-28 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 4,3700 | -2.794 | -12 | 3.058 | ||||
| 2021-06-03 | 2021-06-01 | 4 | Alleva Lawrence M Held by Trust | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 0,7900 | 12.600 | 10 | 12.600 | ||||
| 2021-03-03 | 2021-03-03 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,1570 | 1.785.000 | 280 | 1.800.000 | ||||
| 2021-01-19 | 2021-01-19 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,6695 | -2.111 | -12 | 3.539 | ||||
| 2021-01-19 | 2021-01-19 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,6695 | -4.358 | -25 | 7.346 | ||||
| 2021-01-19 | 2021-01-19 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,6695 | -9.879 | -56 | 13.529 | ||||
| 2021-01-12 | 2021-01-12 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 6,1522 | -2.234 | -14 | 3.768 | ||||
| 2021-01-12 | 2021-01-12 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 6,1522 | -1.058 | -7 | 1.767 | ||||
| 2021-01-12 | 2021-01-12 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 6,1522 | -841 | -5 | 1.396 | ||||
| 2021-01-12 | 2021-01-12 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 6,1522 | -2.707 | -17 | 3.695 | ||||
| 2021-01-11 | 2021-01-11 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 242.712 | 242.712 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 1.086.816 | 1.086.816 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 242.712 | 242.712 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 1.086.816 | 1.086.816 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 728.160 | 728.160 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 3.260.400 | 3.260.400 | |||||
| 2021-01-11 | 2021-01-11 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 242.712 | 242.712 | |||||
| 2021-01-11 | 2021-01-11 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 1.086.816 | 1.086.816 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 242.712 | 242.712 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 1.086.816 | 1.086.816 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 242.712 | 242.712 | |||||
| 2021-01-11 | 2021-01-11 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 1,03 | 1.086.816 | 1.086.816 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3279 | -1.065 | -6 | 1.760 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3279 | -845 | -5 | 1.392 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3279 | -3.499 | -19 | 5.864 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3279 | -4.967 | -26 | 6.737 | ||||
| 2020-12-16 | 2020-12-14 | 4 | Wood Gavin | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,6896 | 24.000 | 17 | 57.000 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Bertrand William C JR | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,6948 | 207.000 | 144 | 284.808 | ||||
| 2020-09-02 | 2020-09-01 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 8,5149 | -2.776 | -24 | 3.076 | ||||
| 2020-08-04 | 2020-08-03 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 9,2500 | -2.788 | -26 | 3.064 | ||||
| 2020-08-04 | 2020-08-03 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | American Depositary Shares | D | 8,7409 | -200.000 | -1.748 | 0 | ||||
| 2020-08-04 | 2020-08-03 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 9,2500 | -4.823 | -45 | 8.066 | ||||
| 2020-07-01 | 2020-07-01 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 184.258 | 184.258 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Furey John | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 196.186 | 196.186 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 197.678 | 197.678 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 144.000 | 144.000 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Duncan Barbara Gayle | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 144.000 | 144.000 | |||||
| 2020-07-01 | 2020-07-01 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 226.753 | 226.753 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 184.258 | 184.258 | |||||
| 2020-07-01 | 2020-07-01 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 1,67 | 179.785 | 179.785 | |||||
| 2020-06-30 | 2020-06-29 | 4 | Wood Gavin | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 1,6200 | 33.000 | 53 | 33.000 | ||||
| 2020-06-11 | 2020-06-09 | 4 | Alleva Lawrence M Held by Trust | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 1,8900 | 12.900 | 24 | 12.900 | ||||
| 2020-06-02 | 2020-05-29 | 4 | Noble James | ADAP | American Depositary Shares | D | 9,3320 | -500.000 | -4.666 | 0 | ||||
| 2020-04-01 | 2020-04-01 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 565.000 | 565.000 | |||||
| 2020-04-01 | 2020-04-01 | 4 | Wood Gavin | ADAP | Option to purchase Ordinary Shares | D | 0,45 | 2.500.000 | 2.500.000 | |||||
| 2020-04-01 | 2020-04-01 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,45 | 31.000 | 31.000 | |||||
| 2020-01-28 | 2020-01-24 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-28 | 2020-01-24 | 4 | Behbahani Ali See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-28 | 2020-01-24 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-28 | 2020-01-24 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-28 | 2020-01-24 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-28 | 2020-01-24 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,6667 | 7.500.000 | 5.000 | 19.500.000 | ||||
| 2020-01-17 | 2020-01-16 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 135.600 | 135.600 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Norry Elliot | ADAP | Option to purchase Ordinary Shares | D | 0,74 | 201.600 | 201.600 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 280.896 | 280.896 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,74 | 1.257.744 | 1.257.744 | |||||
| 2020-01-17 | 2020-01-16 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 280.896 | 280.896 | |||||
| 2020-01-17 | 2020-01-16 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,74 | 1.257.744 | 1.257.744 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 561.792 | 561.792 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,74 | 2.515.536 | 2.515.536 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 280.896 | 280.896 | |||||
| 2020-01-17 | 2020-01-16 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,74 | 1.257.744 | 1.257.744 | |||||
| 2020-01-15 | 2020-01-13 | 4 | Noble James | ADAP | American Depositary Shares | D | 5,0000 | -200.000 | -1.000 | 0 | ||||
| 2020-01-15 | 2020-01-13 | 4 | Noble James | ADAP | American Depositary Shares | D | 4,0000 | -100.000 | -400 | 0 | ||||
| 2020-01-15 | 2020-01-14 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,1347 | -3.236 | -17 | 3.166 | ||||
| 2020-01-15 | 2020-01-14 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,1347 | -1.144 | -6 | 1.681 | ||||
| 2020-01-15 | 2020-01-13 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | American Depositary Shares | D | 5,0000 | -50.000 | -250 | 0 | ||||
| 2020-01-15 | 2020-01-13 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | American Depositary Shares | D | 4,0000 | -50.000 | -200 | 0 | ||||
| 2020-01-15 | 2020-01-14 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,1347 | -2.397 | -12 | 3.605 | ||||
| 2020-01-15 | 2020-01-14 | 4 | Norry Elliot | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,1347 | -911 | -5 | 1.326 | ||||
| 2020-01-13 | 3 | Norry Elliot | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 5.358 | ||||||||
| 2020-01-13 | 3 | Norry Elliot | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 5.358 | ||||||||
| 2020-01-13 | 3 | Norry Elliot | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 5.358 | ||||||||
| 2020-01-07 | 2020-01-06 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,2000 | -5.900 | -7 | 5.804 | ||||
| 2020-01-07 | 2020-01-06 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,2000 | -3.731 | -4 | 5.632 | ||||
| 2020-01-07 | 2020-01-06 | 4 | Lunger John | ADAP | American Depositary Shares representing Ordinary Shares | D | 1,2000 | -1.148 | -1 | 1.677 | ||||
| 2019-09-03 | 2019-09-01 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 140.448 | 140.448 | |||||
| 2019-09-03 | 2019-09-01 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,27 | 628.872 | 628.872 | |||||
| 2019-08-07 | 2019-08-06 | 4 | Amado Rafael | ADAP | American Depositary Shares representing Ordinary Shares | D | 2,0600 | -11.043 | -23 | 17.237 | ||||
| 2019-08-05 | 3 | Lunger John | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 57.612 | ||||||||
| 2019-08-05 | 3 | Lunger John | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 57.612 | ||||||||
| 2019-08-05 | 3 | Lunger John | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 57.612 | ||||||||
| 2019-08-05 | 2019-08-01 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 187.500 | 187.500 | |||||
| 2019-08-05 | 2019-08-01 | 4 | Lunger John | ADAP | Option to purchase Ordinary Shares | D | 0,55 | 839.568 | 839.568 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 234.407 | 234.407 | |||||
| 2019-07-03 | 2019-07-02 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 350.947 | 350.947 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 271.209 | 271.209 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Duncan Barbara Gayle | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 124.000 | 124.000 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 234.407 | 234.407 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Kerr Giles Francis Bertram | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 124.000 | 124.000 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Furey John | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 240.541 | 240.541 | |||||
| 2019-07-03 | 2019-07-02 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 0,61 | 124.000 | 124.000 | |||||
| 2019-06-27 | 2019-06-27 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 140.448 | 140.448 | |||||
| 2019-06-27 | 2019-06-27 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,68 | 628.872 | 628.872 | |||||
| 2019-05-17 | 2019-05-16 | 4 | Noble James | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 0,1430 | 1.773.100 | 254 | 1.773.100 | ||||
| 2019-01-16 | 2019-01-14 | 4 | Rawcliffe Adrian | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3694 | -3.084 | -17 | 3.318 | ||||
| 2019-01-16 | 2019-01-14 | 4 | Amado Rafael | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3694 | -3.028 | -16 | 4.974 | ||||
| 2019-01-16 | 2019-01-14 | 4 | Bertrand William C JR | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3694 | -2.271 | -12 | 3.731 | ||||
| 2019-01-16 | 2019-01-14 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | American Depositary Shares representing Ordinary Shares | D | 5,3694 | -1.514 | -8 | 2.487 | ||||
| 2019-01-08 | 2019-01-04 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 561.792 | 561.792 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,89 | 2.515.536 | 2.515.536 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 224.724 | 224.724 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 0,89 | 1.006.224 | 1.006.224 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 280.896 | 280.896 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,89 | 1.257.744 | 1.257.744 | |||||
| 2019-01-08 | 2019-01-04 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 224.724 | 224.724 | |||||
| 2019-01-08 | 2019-01-04 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,89 | 1.006.224 | 1.006.224 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 224.724 | 224.724 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,89 | 1.006.224 | 1.006.224 | |||||
| 2018-12-19 | 2018-12-17 | 4 | Alleva Lawrence M Held by Trust | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 0,8400 | 47.280 | 40 | 47.280 | ||||
| 2018-10-02 | 2018-10-01 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | American Depositary Shares | D | 13,7900 | -25.000 | -345 | 0 | ||||
| 2018-09-10 | 2018-09-07 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | BARRIS PETER J See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | BASKETT FOREST See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Behbahani Ali See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Florence Anthony A. Jr. See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | MOTT DAVID M See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | SANDELL SCOTT D See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Sonsini Peter W. See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Viswanathan Ravi See Note 5 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 12.000.000 | 20.000 | 12.000.000 | ||||
| 2018-09-10 | 2018-09-07 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,6667 | 3.000.000 | 5.000 | 82.978.668 | ||||
| 2018-08-31 | 2018-08-29 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | American Depositary Shares | D | 10,2500 | -25.000 | -256 | 0 | ||||
| 2018-08-07 | 2018-08-06 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 678.720 | 678.720 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 154.809 | 154.809 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Duncan Barbara Gayle | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 158.233 | 158.233 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Kerr Giles Francis Bertram | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 124.000 | 124.000 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 124.000 | 124.000 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 124.000 | 124.000 | |||||
| 2018-06-26 | 2018-06-22 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 154.809 | 154.809 | |||||
| 2018-06-26 | 2018-06-22 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 2,18 | 187.330 | 187.330 | |||||
| 2018-06-06 | 2018-06-06 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,4900 | -1.600 | -22 | 4.901.310 | ||||
| 2018-06-06 | 2018-06-04 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5700 | -17.100 | -232 | 4.902.910 | ||||
| 2018-06-06 | 2018-06-06 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,4900 | -1.600 | -22 | 4.901.310 | ||||
| 2018-06-06 | 2018-06-04 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5700 | -17.100 | -232 | 4.902.910 | ||||
| 2018-06-01 | 2018-06-01 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,4900 | -50.000 | -674 | 4.920.010 | ||||
| 2018-06-01 | 2018-05-30 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5200 | -121.000 | -1.636 | 4.970.010 | ||||
| 2018-06-01 | 2018-06-01 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,4900 | -50.000 | -674 | 4.920.010 | ||||
| 2018-06-01 | 2018-05-30 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5200 | -121.000 | -1.636 | 4.970.010 | ||||
| 2018-05-16 | 2018-05-14 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5000 | -10.300 | -139 | 5.091.010 | ||||
| 2018-05-16 | 2018-05-14 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 13,5000 | -10.300 | -139 | 5.091.010 | ||||
| 2018-03-29 | 2018-03-29 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 11,5300 | -31.983 | -369 | 5.101.310 | ||||
| 2018-03-29 | 2018-03-27 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 11,5000 | -1.016.084 | -11.685 | 5.133.293 | ||||
| 2018-03-29 | 2018-03-29 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 11,5300 | -31.983 | -369 | 5.101.310 | ||||
| 2018-03-29 | 2018-03-27 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 11,5000 | -1.016.084 | -11.685 | 5.133.293 | ||||
| 2018-03-28 | 2018-03-27 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-28 | 2018-03-27 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9167 | 6.000.000 | 11.500 | 79.978.672 | ||||
| 2018-03-28 | 2018-03-26 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9041 | 571.164 | 1.088 | 73.978.672 | ||||
| 2018-03-23 | 2018-03-23 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-23 | 2018-03-23 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9462 | 294.090 | 572 | 73.407.508 | ||||
| 2018-03-23 | 2018-03-22 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,9040 | 869.574 | 1.656 | 73.113.418 | ||||
| 2018-03-23 | 2018-03-21 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 1,8105 | 104.844 | 190 | 72.243.844 | ||||
| 2018-03-22 | 2018-03-20 | 4 | Rawcliffe Adrian | ADAP | Ordinary Shares | D | 1,7100 | -600.000 | -1.026 | 0 | ||||
| 2018-01-17 | 2018-01-12 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 384.120 | 384.120 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 1.719.936 | 1.719.936 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 192.060 | 192.060 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 859.968 | 859.968 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 144.048 | 144.048 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Bertrand William C JR | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 644.976 | 644.976 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 96.036 | 96.036 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 429.984 | 429.984 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 153.648 | 153.648 | |||||
| 2018-01-17 | 2018-01-12 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 687.984 | 687.984 | |||||
| 2018-01-17 | 2018-01-12 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,00 | 153.648 | 153.648 | |||||
| 2018-01-17 | 2018-01-12 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 1,30 | 687.984 | 687.984 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 144.000 | 144.000 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Duncan Barbara Gayle | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 228.765 | 228.765 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 220.788 | 220.788 | |||||
| 2017-07-03 | 2017-07-03 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 302.561 | 302.561 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 243.724 | 243.724 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Kerr Giles Francis Bertram | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 144.000 | 144.000 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 220.788 | 220.788 | |||||
| 2017-07-03 | 2017-07-03 | 4 | Thompson Peter A. | ADAP | Option to purchase Ordinary Shares | D | 0,75 | 223.779 | 223.779 | |||||
| 2017-03-28 | 2017-03-27 | 4 | Thompson Peter A. See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 4,2000 | 1.190.476 | 5.000 | 6.149.377 | ||||
| 2017-03-28 | 2017-03-27 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | American Depositary Shares representing Ordinary Shares | I | 4,2000 | 1.190.476 | 5.000 | 6.149.377 | ||||
| 2017-03-28 | 2017-03-27 | 4 | KERINS PATRICK J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | MOTT DAVID M See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | SANDELL SCOTT D See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | Sonsini Peter W. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | Viswanathan Ravi See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | New Enterprise Associates 14, L.P. | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | BARRETT M JAMES See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | BARRIS PETER J See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | BASKETT FOREST See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-03-28 | 2017-03-27 | 4 | Florence Anthony A. Jr. See Note 3 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 0,7000 | 12.870.000 | 9.009 | 72.139.000 | ||||
| 2017-01-18 | 2017-01-13 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 0,72 | 2.072.976 | 2.072.976 | |||||
| 2017-01-18 | 2017-01-13 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 0,72 | 2.072.976 | 2.072.976 | |||||
| 2017-01-18 | 2017-01-13 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 0,72 | 2.072.976 | 2.072.976 | |||||
| 2017-01-18 | 2017-01-13 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | Option to purchase Ordinary Shares | D | 0,72 | 2.072.976 | 2.072.976 | |||||
| 2017-01-18 | 2017-01-13 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 0,72 | 2.072.976 | 2.072.976 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Kerr Giles Francis Bertram | ADAP | Option to purchase Ordinary Shares | D | 0,81 | 288.000 | 288.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Zaks Tal Zvi | ADAP | Option to purchase Ordinary Shares | D | 0,81 | 288.000 | 288.000 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Thompson Peter A. | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 186.142 | 186.142 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Alleva Lawrence M | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 196.678 | 196.678 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Behbahani Ali | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 184.562 | 184.562 | |||||
| 2016-08-12 | 2016-08-11 | 4 | MOTT DAVID M | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 191.410 | 191.410 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Laing Ian Michael | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 144.000 | 144.000 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Sigal Charles Elliott | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 184.562 | 184.562 | |||||
| 2016-08-12 | 2016-08-11 | 4 | Knowles Jonathan Kenneth Charles | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 217.222 | 217.222 | |||||
| 2016-05-25 | 2016-05-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,4800 | 518.400 | 5.433 | 29.753.404 | ||||
| 2016-05-25 | 2016-05-23 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,4000 | 1.191.600 | 12.393 | 29.235.004 | ||||
| 2016-05-25 | 2016-05-20 | 4 | ORBIMED ADVISORS LLC See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,0400 | 2.400 | 24 | 28.043.404 | ||||
| 2016-05-25 | 2016-05-24 | 4 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,4800 | 518.400 | 5.433 | 29.753.404 | ||||
| 2016-05-25 | 2016-05-23 | 4 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,4000 | 1.191.600 | 12.393 | 29.235.004 | ||||
| 2016-05-25 | 2016-05-20 | 4 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 10,0400 | 2.400 | 24 | 28.043.404 | ||||
| 2016-05-19 | 2016-05-19 | 4 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 1,5600 | 15.000 | 23 | 314.100 | ||||
| 2016-05-18 | 2016-05-18 | 4 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 1,5500 | 15.000 | 23 | 299.100 | ||||
| 2016-05-18 | 2016-05-17 | 4 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 1,5300 | 15.000 | 23 | 284.100 | ||||
| 2016-05-18 | 2016-05-16 | 4 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 1,5000 | 15.000 | 22 | 269.100 | ||||
| 2016-01-20 | 2016-01-18 | 4 | Rawcliffe Adrian | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 939.948 | 939.948 | |||||
| 2016-01-20 | 2016-01-18 | 4 | Binder-Scholl Gwendolyn Knowlton | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 704.961 | 704.961 | |||||
| 2016-01-20 | 2016-01-18 | 4 | TAYTON-MARTIN HELEN KATRINA | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 939.948 | 939.948 | |||||
| 2016-01-20 | 2016-01-18 | 4 | Noble James | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 1.968.016 | 1.968.016 | |||||
| 2016-01-20 | 2016-01-18 | 4 | Amado Rafael | ADAP | Option to purchase Ordinary Shares | D | 1,27 | 939.948 | 939.948 | |||||
| 2016-01-04 | 3 | Weller Harry R See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Weller Harry R See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Sonsini Peter W. See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Sonsini Peter W. See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | KOLLURI KRISHNA KITTU See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | KOLLURI KRISHNA KITTU See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Florence Anthony A. Jr. See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Florence Anthony A. Jr. See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | BARRIS PETER J See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | BARRIS PETER J See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | NEA 14 GP, LTD | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 118.538.000 | ||||||||
| 2016-01-04 | 3 | NEA 14 GP, LTD | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 118.538.000 | ||||||||
| 2016-01-04 | 3 | NEA 14 GP, LTD | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 118.538.000 | ||||||||
| 2016-01-04 | 3 | NEA 14 GP, LTD | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | D | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 561.138 | ||||||||
| 2016-01-04 | 3 | Sigal Charles Elliott Shares held by Sigal Family Investments, LLC | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 561.138 | ||||||||
| 2016-01-04 | 3 | Sigal Charles Elliott | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 359.976 | ||||||||
| 2016-01-04 | 3 | Sigal Charles Elliott | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 359.976 | ||||||||
| 2016-01-04 | 3 | Laing Ian Michael | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 58.085.600 | ||||||||
| 2016-01-04 | 3 | Laing Ian Michael | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 58.085.600 | ||||||||
| 2016-01-04 | 3 | Alleva Lawrence M | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 141.168 | ||||||||
| 2016-01-04 | 3 | Alleva Lawrence M | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 141.168 | ||||||||
| 2016-01-04 | 3 | Knowles Jonathan Kenneth Charles | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 7.208.768 | ||||||||
| 2016-01-04 | 3 | Knowles Jonathan Kenneth Charles | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 14.205.784 | ||||||||
| 2016-01-04 | 3 | Knowles Jonathan Kenneth Charles | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 7.208.768 | ||||||||
| 2016-01-04 | 3 | Knowles Jonathan Kenneth Charles | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 14.205.784 | ||||||||
| 2016-01-04 | 3 | Amado Rafael | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 192.000 | ||||||||
| 2016-01-04 | 3 | Amado Rafael | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 192.000 | ||||||||
| 2016-01-04 | 3 | TAYTON-MARTIN HELEN KATRINA | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 3.630.000 | ||||||||
| 2016-01-04 | 3 | TAYTON-MARTIN HELEN KATRINA | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 3.630.000 | ||||||||
| 2016-01-04 | 3 | Noble James | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 21.145.200 | ||||||||
| 2016-01-04 | 3 | Noble James | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 12.372.600 | ||||||||
| 2016-01-04 | 3 | Noble James | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 21.145.200 | ||||||||
| 2016-01-04 | 3 | Noble James | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | D | 12.372.600 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | ISALY SAMUEL D See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | BASKETT FOREST See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | BASKETT FOREST See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | BARRETT M JAMES See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | BARRETT M JAMES See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | MOTT DAVID M See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | MOTT DAVID M See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | KERINS PATRICK J See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | KERINS PATRICK J See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | SANDELL SCOTT D See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | SANDELL SCOTT D See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 53.449.304 | ||||||||
| 2016-01-04 | 3 | Thompson Peter A. See Footnotes | ADAP | Ordinary Shares with a nominal value of GBP0.001 per share | I | 30.673.708 | ||||||||
| 2016-01-04 | 3 | Viswanathan Ravi See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 | ||||||||
| 2016-01-04 | 3 | Viswanathan Ravi See Note 1 | ADAP | Ordinary Shares with a nominal value of 0.001 GBP per share | I | 118.538.000 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
