Zentalis Pharmaceuticals, Inc.
US ˙ NasdaqGM ˙ US98943L1070

SecurityZNTL / Zentalis Pharmaceuticals, Inc.
InstitutionBarclays Plc
Latest Disclosed Ownership3,841,449 shares
Ownership 5.32%
Barclays Plc ownership in ZNTL / Zentalis Pharmaceuticals, Inc.

2025-11-12 - Barclays Plc has filed an SCHEDULE 13G form with the Securities and Exchange Commission (SEC) disclosing ownership of 3,841,449 shares of Zentalis Pharmaceuticals, Inc. (US:ZNTL). This represents 5.32 percent ownership of the company.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2025-11-12 2025-11-12 13G 3,841,449 5.32

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 568,443 406,973 252.04 767 215.64 0.0002
2026-03-31 2025-09-30 13F/A-3 ZENTALIS PHARMACEUTICALS COM 98943L107 161,470 161,469 16,146,900.00 244 0.0001
2026-03-19 2025-09-30 13F/A-2 ZENTALIS PHARMACEUTICALS COM 98943L107 75,395 75,394 277 0.0001
2025-11-12 2025-09-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 161,470 161,469 244 0.0001
2026-02-27 2025-06-30 13F/A-2 ZENTALIS PHARMACEUTICALS COM 98943L107 1 -59,615 -100.00 0 -100.00 0.0000
2025-08-14 2025-06-30 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 1 -59,615 0 0.0000
2025-08-13 2025-06-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 1 -59,615 0 0.0000
2026-03-17 2025-03-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 59,616 -57,779 -49.22 95 -73.52 0.0000
2025-05-15 2025-03-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 59,616 -57,779 0 0.0000
2026-03-19 2024-12-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 117,395 42,000 55.71 356 28.16 0.0001
2025-02-13 2024-12-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 117,395 42,000 0 0.0001
2026-03-31 2024-09-30 13F/A-2 ZENTALIS PHARMACEUTICALS COM 98943L107 75,395 11,748 18.46 277 6.54 0.0001
2024-11-19 2024-09-30 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 75,395 11,748 0 0.0001
2024-11-15 2024-09-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 75,395 11,748 0 0.0000
2026-03-23 2024-06-30 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 63,647 -2,670 -4.03 260 -75.12 0.0001
2024-08-14 2024-06-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 63,647 -2,670 0 0.0001
2026-03-24 2024-03-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 66,317 -153,201 -69.79 1,045 -68.57 0.0004
2024-05-15 2024-03-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 66,317 -153,201 1 0.0004
2026-03-25 2023-12-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 219,518 108,701 98.09 3,326 49.64 0.0012
2024-02-15 2023-12-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 219,518 108,701 3 0.0012
2026-03-26 2023-09-30 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 110,817 -101,598 -47.83 2,223 -62.92 0.0014
2023-11-07 2023-09-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 110,817 -101,598 2 0.0014
2026-03-30 2023-06-30 13F/A-2 ZENTALIS PHARMACEUTICALS COM 98943L107 212,415 122,451 136.11 5,992 287.33 0.0038
2023-09-20 2023-06-30 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 212,415 122,451 6 0.0038
2023-08-03 2023-06-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 212,415 122,451 6 0.0038
2026-03-30 2023-03-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 89,964 -37,910 -29.65 1,547 -39.92 0.0007
2023-05-04 2023-03-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 89,964 -37,910 2 0.0007
2026-03-30 2022-12-31 13F/A-1 ZENTALIS PHARMACEUTICALS COM 98943L107 127,874 11,276 9.67 2,575 1.94 0.0012
2023-02-13 2022-12-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 127,874 11,276 3 0.0012
2022-11-03 2022-09-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 116,598 113,153 3,284.56 2,526 2,504.12 0.0028
2022-08-12 2022-06-30 13F ZENTALIS PHARMACEUTICALS COM 98943L107 3,445 -3,409 -49.74 97 -69.30 0.0001
2022-05-16 2022-03-31 13F ZENTALIS PHARMACEUTICALS COM 98943L107 6,854 6,854 316 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.