Xenon Pharmaceuticals Inc.
US ˙ NasdaqGM ˙ CA98420N1050

SecurityXENE / Xenon Pharmaceuticals Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Dimensional Fund Advisors Lp closes position in XENE / Xenon Pharmaceuticals Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 0 shares of Xenon Pharmaceuticals Inc. (US:XENE) valued at $0 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 452,147 shares of Xenon Pharmaceuticals Inc.. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F XENON PHARMACEUTICALS COM 98420N105 0 -100.00 0
2026-02-12 2025-12-31 13F XENON PHARMACEUTICALS COM 98420N105 452,147 -1,876 -0.41 20,261 11.19 0.0043
2025-11-12 2025-09-30 13F XENON PHARMACEUTICALS COM 98420N105 454,023 74,035 19.48 18,222 53.13 0.0039
2025-08-12 2025-06-30 13F XENON PHARMACEUTICALS COM 98420N105 379,988 165,128 76.85 11,900 65.03 0.0028
2025-05-13 2025-03-31 13F XENON PHARMACEUTICALS COM 98420N105 214,860 -45,110 -17.35 7,211 -29.22 0.0018
2025-02-13 2024-12-31 13F XENON PHARMACEUTICALS COM 98420N105 259,970 -39,895 -13.30 10,188 -13.68 0.0024
2024-11-07 2024-09-30 13F XENON PHARMACEUTICALS COM 98420N105 299,865 -136,595 -31.30 11,803 -30.62 0.0029
2024-08-09 2024-06-30 13F XENON PHARMACEUTICALS COM 98420N105 436,460 26,253 6.40 17,011 -3.67 0.0044
2024-05-10 2024-03-31 13F XENON PHARMACEUTICALS COM 98420N105 410,207 7,539 1.87 17,659 -4.79 0.0048
2024-02-07 2023-12-31 13F XENON PHARMACEUTICALS COM 98420N105 402,668 -24,457 -5.73 18,547 27.10 0.0054
2023-11-09 2023-09-30 13F XENON PHARMACEUTICALS COM 98420N105 427,125 165,018 62.96 14,593 44.63 0.0048
2023-08-09 2023-06-30 13F XENON PHARMACEUTICALS COM 98420N105 262,107 196,841 301.60 10,091 332.12 0.0032
2023-05-12 2023-03-31 13F XENON PHARMACEUTICALS COM 98420N105 65,266 -249,407 -79.26 2,336 19,358.33 0.0008
2023-02-09 2022-12-31 13F XENON PHARMACEUTICALS COM 98420N105 314,673 -27,358 -8.00 12 -99.90 0.0037
2022-11-10 2022-09-30 13F XENON PHARMACEUTICALS COM 98420N105 342,031 167,069 95.49 12,348 132.02 0.0047
2022-08-12 2022-06-30 13F XENON PHARMACEUTICALS COM 98420N105 174,962 -118,767 -40.43 5,322 -40.73 0.0019
2022-05-13 2022-03-31 13F XENON PHARMACEUTICALS COM 98420N105 293,729 1,783 0.61 8,979 -1.55 0.0028
2022-02-09 2021-12-31 13F XENON PHARMACEUTICALS COM 98420N105 291,946 140,749 93.09 9,120 294.81 0.0028
2021-11-12 2021-09-30 13F XENON PHARMACEUTICALS COM 98420N105 151,197 136,187 907.31 2,310 727.96 0.0007
2021-08-12 2021-06-30 13F XENON PHARMACEUTICALS COM 98420N105 15,010 3,890 34.98 279 153.64 0.0001
2019-08-13 2019-06-30 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 110 -2.65 0.0000
2019-08-12 2019-03-31 13F/A-2 XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 113 61.43 0.0000
2019-05-10 2019-03-31 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 113
2019-02-26 2018-12-31 13F/A-1 XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 70 -52.38 0.0000
2019-02-13 2018-12-31 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 70
2018-11-13 2018-09-30 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 147 44.12 0.0001
2018-08-10 2018-06-30 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 102 88.89 0.0000
2018-05-11 2018-03-31 13F XENON PHARMACEUTICALS COM 98420N105 11,120 0 0.00 54 74.19 0.0000
2018-02-12 2017-12-31 13F XENON PHARMACEUTICALS COM 98420N105 11,120 11,120 31 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.