uniQure N.V.
US ˙ NasdaqGS ˙ NL0010696654

SecurityQURE / uniQure N.V.
InstitutionSquarepoint Ops LLC
Latest Disclosed Ownership345,983 shares
Latest Disclosed Value $ 5,656,822
Squarepoint Ops LLC reports 96.58% increase in ownership of QURE / uniQure N.V.

On May 15, 2026 - Squarepoint Ops LLC filed a 13F-HR form disclosing ownership of 345,983 shares of uniQure N.V. (US:QURE) valued at $5,656,822 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 176,000 shares of uniQure N.V.. This represents a change in shares of 96.58% during the quarter. The current value of the position is $10,337,972 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F UNIQURE SHS N90064101 345,983 169,983 96.58 5,657 34.31 0.0066
2026-02-13 2025-12-31 13F UNIQURE SHS N90064101 176,000 -5,902 -3.24 4,212 -60.34 0.0045
2025-11-14 2025-09-30 13F UNIQURE SHS N90064101 181,902 5,900 3.35 10,618 332.82 0.0107
2025-08-27 2025-06-30 13F/A-1 UNIQURE SHS N90064101 176,002 -2,330 -1.31 2,453 29.79 0.0026
2025-08-14 2025-06-30 13F UNIQURE SHS N90064101 176,002 -2,330 2,453 0.0026
2025-08-27 2025-03-31 13F/A-1 UNIQURE SHS N90064101 178,332 163,745 1,122.54 1,890 635.41 0.0023
2025-05-15 2025-03-31 13F UNIQURE SHS N90064101 178,332 163,745 1,890 0.0023
2025-02-14 2024-12-31 13F UNIQURE SHS N90064101 14,587 -9,442 -39.29 258 117.80 0.0003
2024-11-14 2024-09-30 13F UNIQURE SHS N90064101 24,029 24,029 118 0.0002
2024-05-15 2024-03-31 13F UNIQURE SHS N90064101 0 -115,292 -100.00 0 -100.00
2024-02-14 2023-12-31 13F UNIQURE SHS N90064101 115,292 115,292 781 0.0015
2023-11-14 2023-09-30 13F UNIQURE SHS N90064101 0 -26,887 -100.00 0 -100.00
2023-08-14 2023-06-30 13F UNIQURE SHS N90064101 26,887 26,887 308 0.0009
2022-05-16 2022-03-31 13F UNIQURE SHS N90064101 0 -20,384 -100.00 0 -100.00
2022-02-14 2021-12-31 13F UNIQURE SHS N90064101 20,384 20,384 423 0.0011
2021-11-15 2021-09-30 13F UNIQURE SHS N90064101 0 -33,712 -100.00 0 -100.00
2021-08-16 2021-06-30 13F UNIQURE SHS N90064101 33,712 1,213 3.73 1,038 -5.21 0.0039
2021-05-17 2021-03-31 13F UNIQURE SHS N90064101 32,499 22,406 222.00 1,095 200.00 0.0064
2021-02-16 2020-12-31 13F UNIQURE SHS N90064101 10,093 -26,843 -72.67 365 -73.16 0.0027
2020-11-16 2020-09-30 13F UNIQURE SHS N90064101 36,936 36,936 1,360 0.0183
2020-08-14 2020-06-30 13F UNIQURE SHS N90064101 0 -6,155 -100.00 0 -100.00
2020-05-15 2020-03-31 13F UNIQURE SHS N90064101 6,155 -13,357 -68.46 292 -79.11 0.0075
2020-02-14 2019-12-31 13F UNIQURE SHS N90064101 19,512 4,267 27.99 1,398 133.00 0.0083
2019-11-14 2019-09-30 13F UNIQURE SHS N90064101 15,245 -22,055 -59.13 600 -79.42 0.0054
2019-08-14 2019-06-30 13F UNIQURE SHS N90064101 37,300 13,774 58.55 2,915 107.77 0.0284
2019-05-15 2019-03-31 13F UNIQURE SHS N90064101 23,526 8,208 53.58 1,403 218.14 0.0149
2019-02-14 2018-12-31 13F UNIQURE SHS N90064101 15,318 -11,043 -41.89 441 -54.01 0.0051
2018-11-14 2018-09-30 13F UNIQURE SHS N90064101 26,361 -35,556 -57.43 959 -59.02 0.0115
2018-08-14 2018-06-30 13F UNIQURE SHS N90064101 61,917 23,972 63.18 2,340 162.33 0.0310
2018-05-15 2018-03-31 13F UNIQURE SHS N90064101 37,945 37,945 892 0.0142
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.