Organogenesis Holdings Inc.
US ˙ NasdaqCM ˙ US68621F1021

SecurityORGO / Organogenesis Holdings Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership2,297,974 shares
Latest Disclosed Value $ 5,446,198
D. E. Shaw & Co., Inc. reports 15.56% increase in ownership of ORGO / Organogenesis Holdings Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 2,297,974 shares of Organogenesis Holdings Inc. (US:ORGO) valued at $5,446,198 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,988,479 shares of Organogenesis Holdings Inc.. This represents a change in shares of 15.56% during the quarter. The current value of the position is $5,354,279 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ORGANOGENESIS HLDGS COM 68621F102 2,297,974 309,495 15.56 5,446 -47.13 0.0033
2026-02-17 2025-12-31 13F ORGANOGENESIS HLDGS COM 68621F102 1,988,479 1,476,843 288.65 10,300 377.07 0.0056
2025-11-14 2025-09-30 13F ORGANOGENESIS HLDGS COM 68621F102 511,636 -101,423 -16.54 2,159 -3.74 0.0012
2025-08-14 2025-06-30 13F ORGANOGENESIS HLDGS COM 68621F102 613,059 -271,229 -30.67 2,244 -41.28 0.0016
2025-05-15 2025-03-31 13F ORGANOGENESIS HLDGS COM 68621F102 884,288 146,845 19.91 3,820 61.93 0.0034
2025-02-14 2024-12-31 13F ORGANOGENESIS HLDGS COM 68621F102 737,443 -672 -0.09 2,360 11.75 0.0017
2024-11-14 2024-09-30 13F ORGANOGENESIS HLDGS COM 68621F102 738,115 -3,818 -0.51 2,111 1.64 0.0018
2024-08-14 2024-06-30 13F ORGANOGENESIS HLDGS COM 68621F102 741,933 109,189 17.26 2,077 15.65 0.0019
2024-05-15 2024-03-31 13F ORGANOGENESIS HLDGS COM 68621F102 632,744 -334,128 -34.56 1,797 -54.58 0.0015
2024-02-14 2023-12-31 13F ORGANOGENESIS HLDGS COM 68621F102 966,872 -119,346 -10.99 3,955 14.48 0.0035
2023-11-14 2023-09-30 13F ORGANOGENESIS HLDGS COM 68621F102 1,086,218 -184,747 -14.54 3,454 -18.13 0.0036
2023-08-14 2023-06-30 13F ORGANOGENESIS HLDGS COM 68621F102 1,270,965 -69,878 -5.21 4,220 47.78 0.0043
2023-05-15 2023-03-31 13F ORGANOGENESIS HLDGS COM 68621F102 1,340,843 909,003 210.50 2,856 145.91 0.0031
2023-02-14 2022-12-31 13F ORGANOGENESIS HLDGS COM 68621F102 431,840 237,062 121.71 1,162 83.99 0.0013
2022-11-14 2022-09-30 13F ORGANOGENESIS HLDGS COM 68621F102 194,778 43,523 28.77 631 -14.50 0.0008
2022-08-15 2022-06-30 13F ORGANOGENESIS HLDGS COM 68621F102 151,255 87,490 137.21 738 51.85 0.0009
2022-05-16 2022-03-31 13F ORGANOGENESIS HLDGS COM 68621F102 63,765 -12,740 -16.65 486 -31.26 0.0005
2022-02-14 2021-12-31 13F ORGANOGENESIS HLDGS COM 68621F102 76,505 -56,812 -42.61 707 -62.77 0.0006
2021-11-15 2021-09-30 13F ORGANOGENESIS HLDGS COM 68621F102 133,317 88,723 198.96 1,899 156.28 0.0017
2021-08-16 2021-06-30 13F ORGANOGENESIS HLDGS COM 68621F102 44,594 44,594 741 0.0006
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.