OptimizeRx Corporation
US ˙ NasdaqCM ˙ US68401U2042

SecurityOPRX / OptimizeRx Corporation
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership142,923 shares
Latest Disclosed Value $ 897,556
D. E. Shaw & Co., Inc. reports 26.63% increase in ownership of OPRX / OptimizeRx Corporation

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 142,923 shares of OptimizeRx Corporation (US:OPRX) valued at $897,556 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 112,867 shares of OptimizeRx Corporation. This represents a change in shares of 26.63% during the quarter. The current value of the position is $707,469 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OPTIMIZERX COM NEW 68401U204 142,923 30,056 26.63 898 -35.14 0.0005
2026-02-17 2025-12-31 13F OPTIMIZERX COM NEW 68401U204 112,867 -208,184 -64.84 1,384 -78.98 0.0008
2025-11-14 2025-09-30 13F OPTIMIZERX COM NEW 68401U204 321,051 -91,845 -22.24 6,582 18.07 0.0037
2025-08-14 2025-06-30 13F OPTIMIZERX COM NEW 68401U204 412,896 62,977 18.00 5,574 83.96 0.0040
2025-05-15 2025-03-31 13F OPTIMIZERX COM NEW 68401U204 349,919 54,202 18.33 3,030 110.86 0.0027
2025-02-14 2024-12-31 13F OPTIMIZERX COM NEW 68401U204 295,717 32,062 12.16 1,437 -29.39 0.0011
2024-11-14 2024-09-30 13F OPTIMIZERX COM NEW 68401U204 263,655 -44,679 -14.49 2,035 -33.99 0.0017
2024-08-14 2024-06-30 13F OPTIMIZERX COM NEW 68401U204 308,334 -40,558 -11.62 3,083 -27.27 0.0029
2024-05-15 2024-03-31 13F OPTIMIZERX COM NEW 68401U204 348,892 -113,615 -24.57 4,239 -35.95 0.0036
2024-02-14 2023-12-31 13F OPTIMIZERX COM NEW 68401U204 462,507 -137,886 -22.97 6,618 41.68 0.0058
2023-11-14 2023-09-30 13F OPTIMIZERX COM NEW 68401U204 600,393 64,414 12.02 4,671 -39.01 0.0049
2023-08-14 2023-06-30 13F OPTIMIZERX COM NEW 68401U204 535,979 64,747 13.74 7,659 11.10 0.0078
2023-05-15 2023-03-31 13F OPTIMIZERX COM NEW 68401U204 471,232 286,250 154.74 6,894 121.89 0.0074
2023-02-14 2022-12-31 13F OPTIMIZERX COM NEW 68401U204 184,982 100,553 119.10 3,108 148.36 0.0034
2022-11-14 2022-09-30 13F OPTIMIZERX COM NEW 68401U204 84,429 84,429 1,251 0.0015
2021-08-16 2021-06-30 13F OPTIMIZERX COM NEW 68401U204 0 -8,838 -100.00 0 -100.00
2021-05-17 2021-03-31 13F OPTIMIZERX COM NEW 68401U204 8,838 -10,385 -54.02 431 -28.05 0.0004
2021-02-16 2020-12-31 13F OPTIMIZERX COM NEW 68401U204 19,223 19,223 599 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.