Nautilus Biotechnology, Inc.
US ˙ NasdaqCM ˙ US63909J1088

SecurityNAUT / Nautilus Biotechnology, Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership329,123 shares
Latest Disclosed Value $ 1,273,767
Dimensional Fund Advisors Lp reports 15.30% increase in ownership of NAUT / Nautilus Biotechnology, Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 329,123 shares of Nautilus Biotechnology, Inc. (US:NAUT) valued at $1,276,997 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 285,439 shares of Nautilus Biotechnology, Inc.. This represents a change in shares of 15.30% during the quarter. The current value of the position is $786,604 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 329,123 43,684 15.30 1,274 128.96 0.0001
2026-02-12 2025-12-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 285,439 -79,236 -21.73 556 81.11 0.0001
2025-11-12 2025-09-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 364,675 -186,065 -33.78 308 -23.06 0.0001
2025-08-12 2025-06-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 550,740 -109,178 -16.54 399 -29.75 0.0001
2025-05-13 2025-03-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 659,918 -110,435 -14.34 568 -56.11 0.0001
2025-02-13 2024-12-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 770,353 78,367 11.32 1,294 -34.38 0.0003
2024-11-07 2024-09-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 691,986 117,142 20.38 1,973 46.73 0.0005
2024-08-09 2024-06-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 574,844 94,908 19.78 1,345 -4.75 0.0004
2024-05-10 2024-03-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 479,936 78,911 19.68 1,411 17.58 0.0004
2024-02-07 2023-12-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 401,025 158,073 65.06 1,200 56.45 0.0004
2023-11-09 2023-09-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 242,952 162,991 203.84 767 149.84 0.0003
2023-08-09 2023-06-30 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 79,961 53,091 197.58 308 314.86 0.0001
2023-05-12 2023-03-31 13F NAUTILUS BIOTECHNOLOGY COM 63909J108 26,870 26,870 74 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.