Lexicon Pharmaceuticals, Inc.
US ˙ NasdaqCM ˙ US5288723027

SecurityLXRX / Lexicon Pharmaceuticals, Inc.
InstitutionPinnacle Associates Ltd
Latest Disclosed Ownership29,015 shares
Latest Disclosed Value $ 45,263
Pinnacle Associates Ltd ownership in LXRX / Lexicon Pharmaceuticals, Inc.

On April 21, 2026 - Pinnacle Associates Ltd filed a 13F-HR form disclosing ownership of 29,015 shares of Lexicon Pharmaceuticals, Inc. (US:LXRX) valued at $45,263 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 5, 2026 disclosing 29,015 shares of Lexicon Pharmaceuticals, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $55,419 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-21 2026-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 29,015 0 0.00 45 36.36 0.0006
2026-02-05 2025-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 29,015 -21,800 -42.90 33 -51.47 0.0004
2025-11-13 2025-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 50,815 0 0.00 69 41.67 0.0009
2025-08-04 2025-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 50,815 -3,365 -6.21 48 100.00 0.0007
2025-05-06 2025-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 54,180 -1,371,112 -96.20 25 -97.72 0.0004
2025-02-14 2024-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,425,292 -305,529 -17.65 1,053 -60.27 0.0143
2024-10-25 2024-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,730,821 14,990 0.87 2,648 -8.12 0.0450
2024-07-30 2024-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,715,831 -31,999 -1.83 2,883 -31.28 0.0451
2024-04-26 2024-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,747,830 17,009 0.98 4,195 58.38 0.0661
2024-01-19 2023-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,730,821 -182,048 -9.52 2,648 27.00 0.0446
2023-10-24 2023-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,912,869 -80,758 -4.05 2,085 -54.33 0.0388
2023-07-27 2023-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,993,627 53,403 2.75 4,565 -3.16 0.0792
2023-05-05 2023-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,940,224 7,447 0.39 4,715 27.72 0.0964
2023-02-01 2022-12-31 13F/A-1 LEXICON PHARMACEUTICALS COM NEW 528872302 1,932,777 -98,430 -4.85 3,692 -24.29 0.0804
2023-01-25 2022-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,983,522 -47,685 4,225 0.0001
2022-11-01 2022-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,031,207 -56,256 -2.69 4,875 25.55 0.1119
2022-08-02 2022-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,087,463 -6,831 -0.33 3,883 -11.29 0.0847
2022-05-05 2022-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,094,294 -33,368 -1.57 4,377 -47.79 0.0775
2022-02-02 2021-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,127,662 30,015 1.43 8,383 -16.92 0.1446
2021-10-19 2021-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,097,647 -93,135 -4.25 10,090 0.34 0.1860
2021-08-02 2021-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,190,782 23,610 1.09 10,056 -20.95 0.1818
2021-05-12 2021-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 2,167,172 314,790 16.99 12,721 100.81 0.2426
2021-01-26 2020-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 1,852,382 1,505,122 433.43 6,335 1,167.00 0.1286
2020-10-23 2020-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 347,260 -11,250 -3.14 500 -30.07 0.0119
2020-08-14 2020-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 358,510 2,165 0.61 715 2.88 0.0176
2020-05-13 2020-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 356,345 -43,029 -10.77 695 -58.06 0.0211
2020-02-03 2019-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 399,374 -71,975 -15.27 1,657 16.77 0.0363
2019-11-08 2019-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 471,349 -39,485 -7.73 1,419 -55.84 0.0334
2019-08-05 2019-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 510,834 -39,715 -7.21 3,213 4.97 0.0752
2019-05-10 2019-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 550,549 9,615 1.78 3,061 -14.78 0.0692
2019-02-05 2018-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 540,934 -37,785 -6.53 3,592 -41.83 0.0927
2018-11-09 2018-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 578,719 -96,106 -14.24 6,175 -23.75 0.1281
2018-08-08 2018-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 674,825 -115,860 -14.65 8,098 19.51 0.1666
2018-05-11 2018-03-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 790,685 -63,490 -7.43 6,776 -19.71 0.1328
2018-02-12 2017-12-31 13F LEXICON PHARMACEUTICALS COM NEW 528872302 854,175 -42,870 -4.78 8,439 -23.46 0.1621
2017-11-13 2017-09-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 897,045 182,215 25.49 11,025 -6.24 0.2033
2017-08-09 2017-06-30 13F LEXICON PHARMACEUTICALS COM NEW 528872302 714,830 714,830 11,759 0.2260
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.