Opus Genetics, Inc.
US ˙ NasdaqCM ˙ US67577R1023

SecurityIRD / Opus Genetics, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership199,953 shares
Latest Disclosed Value $ 909,786
State Street Corp reports 15.41% increase in ownership of IRD / Opus Genetics, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 199,953 shares of Opus Genetics, Inc. (US:IRD) valued at $909,786 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 173,253 shares of Opus Genetics, Inc.. This represents a change in shares of 15.41% during the quarter. The current value of the position is $839,803 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OPUS GENETICS COM 67577R102 199,953 26,700 15.41 910 161.21 0.0000
2026-02-13 2025-12-31 13F OPUS GENETICS COM 67577R102 173,253 27,380 18.77 348 45.00 0.0000
2025-11-14 2025-09-30 13F OPUS GENETICS COM 67577R102 145,873 75,400 106.99 241 263.64 0.0000
2025-08-14 2025-06-30 13F OPUS GENETICS COM 67577R102 70,473 0 0.00 66 -4.35 0.0000
2025-05-15 2025-03-31 13F OPUS GENETICS COM 67577R102 70,473 0 0.00 69 -16.87 0.0000
2025-02-14 2024-12-31 13F OPUS GENETICS COM 67577R102 70,473 0 0.00 84 -9.78 0.0000
2024-11-14 2024-09-30 13F OCUPHIRE PHARMA COM 67577R102 70,473 0 0.00 92 -14.02 0.0000
2024-08-14 2024-06-30 13F OCUPHIRE PHARMA COM 67577R102 70,473 0 0.00 108 -24.11 0.0000
2024-05-15 2024-03-31 13F OCUPHIRE PHARMA COM 67577R102 70,473 0 0.00 142 -33.49 0.0000
2024-02-14 2023-12-31 13F OCUPHIRE PHARMA COM 67577R102 70,473 17,600 33.29 212 19.77 0.0000
2023-11-14 2023-09-30 13F OCUPHIRE PHARMA COM 67577R102 52,873 0 0.00 177 -22.71 0.0000
2023-08-14 2023-06-30 13F OCUPHIRE PHARMA COM 67577R102 52,873 -9,300 -14.96 229 -1.72 0.0000
2023-05-15 2023-03-31 13F OCUPHIRE PHARMA COM 67577R102 62,173 0 0.00 233 6.39 0.0000
2023-05-15 2022-12-31 13F/A-99 OCUPHIRE PHARMA COM 67577R102 62,173 0 0.00 219 75.20 0.0000
2023-05-15 2022-12-31 13F OCUPHIRE PHARMA COM 67577R102 62,173 0 219 0.0000
2022-11-15 2022-09-30 13F OCUPHIRE PHARMA COM 67577R102 62,173 0 0.00 125 5.04 0.0000
2022-08-15 2022-06-30 13F OCUPHIRE PHARMA COM 67577R102 62,173 0 0.00 119 -40.80 0.0000
2022-05-16 2022-03-31 13F OCUPHIRE PHARMA COM 67577R102 62,173 -14,000 -18.38 201 -29.23 0.0000
2022-02-14 2021-12-31 13F OCUPHIRE PHARMA COM 67577R102 76,173 61,200 408.74 284 268.83 0.0000
2021-11-15 2021-09-30 13F OCUPHIRE PHARMA COM 67577R102 14,973 -39,600 -72.56 77 -73.26 0.0000
2021-08-16 2021-06-30 13F OCUPHIRE PHARMA COM 67577R102 54,573 54,573 288 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.