Opus Genetics, Inc.
US ˙ NasdaqCM ˙ US67577R1023

SecurityIRD / Opus Genetics, Inc.
InstitutionGeode Capital Management, Llc
Latest Disclosed Ownership538,347 shares
Latest Disclosed Value $ 2,451,169
Geode Capital Management, Llc reports 6.61% increase in ownership of IRD / Opus Genetics, Inc.

On May 15, 2026 - Geode Capital Management, Llc filed a 13F-HR form disclosing ownership of 538,347 shares of Opus Genetics, Inc. (US:IRD) valued at $2,449,479 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 504,983 shares of Opus Genetics, Inc.. This represents a change in shares of 6.61% during the quarter. The current value of the position is $2,169,538 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OPUS GENETICS COM 67577R102 538,347 33,364 6.61 2,451 141.48 0.0001
2026-02-09 2025-12-31 13F OPUS GENETICS COM 67577R102 504,983 36,046 7.69 1,016 31.31 0.0001
2025-11-12 2025-09-30 13F OPUS GENETICS COM 67577R102 468,937 113,260 31.84 774 130.75 0.0000
2025-08-08 2025-06-30 13F OPUS GENETICS COM 67577R102 355,677 2,268 0.64 335 -3.46 0.0000
2025-05-13 2025-03-31 13F OPUS GENETICS COM 67577R102 353,409 39,425 12.56 347 -6.97 0.0000
2025-02-12 2024-12-31 13F OPUS GENETICS COM 67577R102 313,984 41,703 15.32 374 4.78 0.0000
2024-11-12 2024-09-30 13F OCUPHIRE PHARMA COM 67577R102 272,281 6,427 2.42 357 -12.32 0.0000
2024-08-09 2024-06-30 13F OCUPHIRE PHARMA COM 67577R102 265,854 31,456 13.42 407 -13.80 0.0000
2024-05-13 2024-03-31 13F OCUPHIRE PHARMA COM 67577R102 234,398 15,285 6.98 471 -28.53 0.0000
2024-02-13 2023-12-31 13F OCUPHIRE PHARMA COM 67577R102 219,113 0 0.00 660 -10.22 0.0001
2023-11-13 2023-09-30 13F OCUPHIRE PHARMA COM 67577R102 219,113 25,064 12.92 734 -12.83 0.0001
2023-08-11 2023-06-30 13F OCUPHIRE PHARMA COM 67577R102 194,049 12,679 6.99 842 23.82 0.0001
2023-05-15 2023-03-31 13F OCUPHIRE PHARMA COM 67577R102 181,370 8,303 4.80 680 0.0001
2023-02-13 2022-12-31 13F OCUPHIRE PHARMA COM 67577R102 173,067 21,498 14.18 1 -100.00 0.0001
2022-11-14 2022-09-30 13F OCUPHIRE PHARMA COM 67577R102 151,569 4,110 2.79 304 7.42 0.0000
2022-08-12 2022-06-30 13F OCUPHIRE PHARMA COM 67577R102 147,459 17,535 13.50 283 -32.62 0.0000
2022-05-13 2022-03-31 13F OCUPHIRE PHARMA COM 67577R102 129,924 38,856 42.67 420 23.89 0.0001
2022-02-11 2021-12-31 13F OCUPHIRE PHARMA COM 67577R102 91,068 12,145 15.39 339 -16.50 0.0000
2021-11-12 2021-09-30 13F OCUPHIRE PHARMA COM 67577R102 78,923 53,329 208.37 406 200.74 0.0001
2021-08-13 2021-06-30 13F OCUPHIRE PHARMA COM 67577R102 25,594 14,294 126.50 135 107.69 0.0000
2021-05-12 2021-03-31 13F OCUPHIRE PHARMA COM 67577R102 11,300 11,300 65 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.