Heron Therapeutics, Inc.
US ˙ NasdaqCM ˙ US4277461020

SecurityHRTX / Heron Therapeutics, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership2,586,932 shares
Ownership 2.18%
State Street Corp ownership in HRTX / Heron Therapeutics, Inc.

2023-01-10 - State Street Corp has filed an SC 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,586,932 shares of Heron Therapeutics, Inc. (US:HRTX). This represents 2.18 percent ownership of the company. In their previous filing dated 2022-04-11 , State Street Corp had reported owning 12,923,369 shares, indicating a decrease of -79.98 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date		Effective
Date		Form Prev
Shares		 Latest
Shares		 ΔShares
(Percent)		 Ownership
(Percent)		 ΔOwnership
(Percent)
2023-01-10 2023-01-10 13G/A 12,923,369 2,586,932 -79.98 2.18 -82.77
2022-04-11 2022-04-11 13G/A 7,692,411 12,923,369 68.00 12.65 67.55
2022-02-11 2022-02-11 13G 7,692,411 7.55

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F HERON THERAPEUTICS COM 427746102 3,843,672 65,629 1.74 3,075 -37.39 0.0001
2026-02-13 2025-12-31 13F HERON THERAPEUTICS COM 427746102 3,778,043 126,540 3.47 4,911 6.76 0.0002
2025-11-14 2025-09-30 13F HERON THERAPEUTICS COM 427746102 3,651,503 189,237 5.47 4,601 -35.81 0.0002
2025-08-14 2025-06-30 13F HERON THERAPEUTICS COM 427746102 3,462,266 208,362 6.40 7,167 0.11 0.0003
2025-05-15 2025-03-31 13F HERON THERAPEUTICS COM 427746102 3,253,904 107,711 3.42 7,159 48.72 0.0003
2025-02-14 2024-12-31 13F HERON THERAPEUTICS COM 427746102 3,146,193 -46,243 -1.45 4,814 -24.23 0.0002
2024-11-14 2024-09-30 13F HERON THERAPEUTICS COM 427746102 3,192,436 -2,088,430 -39.55 6,353 -65.63 0.0003
2024-08-14 2024-06-30 13F HERON THERAPEUTICS COM 427746102 5,280,866 2,839,996 116.35 18,483 173.38 0.0008
2024-05-15 2024-03-31 13F HERON THERAPEUTICS COM 427746102 2,440,870 -40,975 -1.65 6,761 60.25 0.0003
2024-02-14 2023-12-31 13F HERON THERAPEUTICS COM 427746102 2,481,845 80,283 3.34 4,219 70.60 0.0002
2023-11-14 2023-09-30 13F HERON THERAPEUTICS COM 427746102 2,401,562 70,324 3.02 2,474 -8.54 0.0001
2023-08-14 2023-06-30 13F HERON THERAPEUTICS COM 427746102 2,331,238 -224,755 -8.79 2,704 -29.93 0.0001
2023-05-15 2023-03-31 13F HERON THERAPEUTICS COM 427746102 2,555,993 -30,939 -1.20 3,860 -40.33 0.0002
2023-05-15 2022-12-31 13F/A-99 HERON THERAPEUTICS COM 427746102 2,586,932 -6,251,774 -70.73 6,467 -82.66 0.0004
2023-05-15 2022-12-31 13F HERON THERAPEUTICS COM 427746102 2,586,932 -6,251,774 6,467 0.0004
2022-11-15 2022-09-30 13F HERON THERAPEUTICS COM 427746102 8,838,706 -7,490,090 -45.87 37,299 -18.13 0.0024
2022-08-15 2022-06-30 13F HERON THERAPEUTICS COM 427746102 16,328,796 3,405,427 26.35 45,557 -38.37 0.0027
2022-05-16 2022-03-31 13F HERON THERAPEUTICS COM 427746102 12,923,369 5,230,958 68.00 73,922 5.25 0.0037
2022-02-14 2021-12-31 13F HERON THERAPEUTICS COM 427746102 7,692,411 1,200,504 18.49 70,232 1.20 0.0033
2021-11-15 2021-09-30 13F HERON THERAPEUTICS COM 427746102 6,491,907 1,779,188 37.75 69,398 -5.12 0.0037
2021-08-16 2021-06-30 13F HERON THERAPEUTICS COM 427746102 4,712,719 128,420 2.80 73,141 -1.57 0.0039
2021-07-09 2021-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 4,584,299 602,495 15.13 74,311 -11.82 0.0043
2021-05-17 2021-03-31 13F HERON THERAPEUTICS COM 427746102 4,584,299 602,495 74,311 0.0043
2021-02-16 2020-12-31 13F HERON THERAPEUTICS COM 427746102 3,981,804 -428,430 -9.71 84,275 28.94 0.0052
2020-11-10 2020-09-30 13F HERON THERAPEUTICS COM 427746102 4,410,234 569,776 14.84 65,360 15.70 0.0045
2020-08-14 2020-06-30 13F HERON THERAPEUTICS COM 427746102 3,840,458 410,333 11.96 56,493 40.29 0.0041
2020-06-19 2020-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 3,430,125 54,068 1.60 40,270 -49.24 0.0035
2020-05-11 2020-03-31 13F HERON THERAPEUTICS COM 427746102 3,430,125 54,068 40,270 3,536.5168
2020-02-06 2019-12-31 13F HERON THERAPEUTICS COM 427746102 3,376,057 663,063 24.44 79,337 58.07 0.0054
2019-11-14 2019-09-30 13F HERON THERAPEUTICS COM 427746102 2,712,994 -1,349,319 -33.22 50,190 -33.54 0.0037
2019-08-14 2019-06-30 13F HERON THERAPEUTICS COM 427746102 4,062,313 829,686 25.67 75,518 -4.41 0.0056
2019-05-15 2019-03-31 13F HERON THERAPEUTICS COM 427746102 3,232,627 -253,365 -7.27 79,005 -12.63 0.0062
2019-02-12 2018-12-31 13F HERON THERAPEUTICS COM 427746102 3,485,992 236,508 7.28 90,427 -12.08 0.0082
2018-11-09 2018-09-30 13F HERON THERAPEUTICS Common equity shares 427746102 3,249,484 -217,402 -6.27 102,848 -23.64 0.0079
2018-08-14 2018-06-30 13F HERON THERAPEUTICS Common equity shares 427746102 3,466,886 323,336 10.29 134,688 55.24 0.0113
2018-05-15 2018-03-31 13F HERON THERAPEUTICS Common equity shares 427746102 3,143,550 914,527 41.03 86,761 115.06 0.0074
2018-02-14 2017-12-31 13F HERON THERAPEUTICS Common equity shares 427746102 2,229,023 308,202 16.05 40,343 30.04 0.0032
2017-11-14 2017-09-30 13F HERON THERAPEUTICS Common equity shares 427746102 1,920,821 183,512 10.56 31,023 28.92 0.0027
2017-08-14 2017-06-30 13F HERON THERAPEUTICS Common equity shares 427746102 1,737,309 -50,369 -2.82 24,063 -10.29 0.0021
2017-05-15 2017-03-31 13F HERON THERAPEUTICS Common equity shares 427746102 1,787,678 420,113 30.72 26,822 49.73 0.0024
2017-02-09 2016-12-31 13F HERON THERAPEUTICS Common equity shares 427746102 1,367,565 270,022 24.60 17,913 -5.30 0.0017
2017-01-13 2016-09-30 13F/A-1 HERON THERAPEUTICS Common equity shares 427746102 1,097,543 103,311 10.39 18,915 5.41 0.0019
2016-11-14 2016-09-30 13F HERON THERAPEUTICS Common equity shares 427746102 1,097,543 18,915
2016-08-12 2016-06-30 13F HERON THERAPEUTICS Common equity shares 427746102 994,232 -214,340 -17.73 17,944 -21.80 0.0019
2016-05-20 2016-03-31 13F/A-1 HERON THERAPEUTICS Common equity shares 427746102 1,208,572 -215,739 -15.15 22,947 -39.66 0.0025
2016-05-12 2016-03-31 13F HERON THERAPEUTICS Common equity shares 427746102 1,208,572 22,947
2016-02-16 2015-12-31 13F HERON THERAPEUTICS Common equity shares 427746102 1,424,311 326,874 29.79 38,027 42.02 0.0042
2015-11-16 2015-09-30 13F HERON THERAPEUTICS Common equity shares 427746102 1,097,437 -101,140 -8.44 26,776 -28.30 0.0031
2015-08-13 2015-06-30 13F HERON THERAPEUTICS Common equity shares 427746102 1,198,577 900,822 302.54 37,346 761.50 0.0040
2015-05-15 2015-03-31 13F HERON THERAPEUTICS Common equity shares 427746102 297,755 68,163 29.69 4,335 87.74 0.0004
2015-02-11 2014-12-31 13F HERON THERAPEUTICS Common equity shares 427746102 229,592 15,227 7.10 2,309 29.65 0.0002
2014-11-12 2014-09-30 13F/A-1 HERON THERAPEUTICS Common equity shares 427746102 214,365 29,203 15.77 1,781 -21.92 0.0002
2014-11-10 2014-09-30 13F HERON THERAPEUTICS Common equity shares 427746102 214,365 1,781
2014-08-12 2014-06-30 13F HERON THERAPEUTICS Common equity shares 427746102 185,162 172,762 1,393.24 2,281 1,218.50 0.0002
2014-05-15 2014-03-31 13F/A-1 HERON THERAPEUTICS Common equity shares 427746102 12,400 12,400 173 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.