Amicus Therapeutics, Inc.
US ˙ NasdaqGM ˙ US03152W1099
DETTE SYMBOL ER IKKE LÆNGERE AKTIVT

SecurityFOLD / Amicus Therapeutics, Inc.
InstitutionPerceptive Advisors Llc
ManagerJoseph Edelman
Latest Disclosed Ownership7,412,830 shares
Ownership 2.40%
Perceptive Advisors Llc ownership in FOLD / Amicus Therapeutics, Inc.

2025-08-14 - Perceptive Advisors Llc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 7,412,830 shares of Amicus Therapeutics, Inc. (US:FOLD). This represents 2.4 percent ownership of the company. In their previous filing dated 2025-05-15 , Perceptive Advisors Llc had reported owning 21,464,527 shares, indicating a decrease of -65.46 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2025-08-14 2025-08-14 13G/A 21,464,527 7,412,830 -65.46 2.40 -65.71
2025-05-15 2025-05-15 13G/A 24,245,952 21,464,527 -11.47 7.00 -13.58
2025-02-14 2025-02-14 13G/A 28,057,456 24,245,952 -13.58 8.10 -15.62
2024-02-14 2024-02-14 13G/A 27,642,917 28,057,456 1.50 9.60 -2.04
2023-02-14 2023-02-14 13G/A 27,356,043 27,642,917 1.05 9.80 1.03
2022-03-02 2022-03-02 13G 26,559,443 27,356,043 3.00 9.70 2.11
2022-03-02 2022-03-02 13D/A 26,559,443 27,356,043 3.00 9.70 2.11
2022-02-22 2022-02-22 13D 26,559,443 26,559,443 0.00 9.50 0.00
2022-02-14 2022-02-14 13G/A 25,112,048 26,559,443 5.76 9.50 -2.06
2021-02-16 2021-02-16 13G/A 25,132,364 25,112,048 -0.08 9.70 -2.02
2020-02-14 2020-02-14 13G/A 20,724,424 25,132,364 21.27 9.90 4.21
2019-02-14 2019-02-14 13G/A 17,888,597 20,724,424 15.85 9.50 -12.04
2018-02-14 2018-02-14 13G/A 17,296,672 17,888,597 3.42 10.80 -10.74
2017-02-14 2017-02-14 13G/A 15,239,444 17,296,672 13.50 12.10 -0.82
2016-02-16 2016-02-16 13G/A 15,239,444 12.20
2015-02-17 2015-02-17 13G/A 14,439,444 15.50
2014-06-03 2014-06-03 13G 8,339,444 12.96

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-29 2026-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 0 -100.00 0
2026-05-15 2026-03-31 13F AMICUS THERAPEUTICS COM 03152W109 0 -100.00 0
2026-02-17 2025-12-31 13F AMICUS THERAPEUTICS COM 03152W109 6,370,851 0 0.00 90,721 80.71 1.6170
2025-11-14 2025-09-30 13F AMICUS THERAPEUTICS COM 03152W109 6,370,851 -1,041,979 -14.06 50,202 18.19 1.4496
2025-08-14 2025-06-30 13F AMICUS THERAPEUTICS COM 03152W109 7,412,830 -14,051,697 -65.46 42,476 -75.75 1.5747
2025-08-06 2025-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 21,464,527 -2,781,425 -11.47 175,151 -23.31 6.1875
2025-05-15 2025-03-31 13F AMICUS THERAPEUTICS COM 03152W109 21,464,527 -2,781,425 175,151 6.1712
2025-02-14 2024-12-31 13F AMICUS THERAPEUTICS COM 03152W109 24,245,952 -3,811,504 -13.58 228,397 -23.78 6.2942
2024-11-14 2024-09-30 13F AMICUS THERAPEUTICS COM 03152W109 28,057,456 0 0.00 299,654 7.66 6.3395
2024-08-16 2024-06-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 28,057,456 0 0.00 278,330 -15.79 6.7039
2024-08-14 2024-06-30 13F AMICUS THERAPEUTICS COM 03152W109 28,057,456 0 278,330 6.6278
2024-08-06 2024-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 28,057,456 0 0.00 330,517 -16.98 5.7828
2024-05-15 2024-03-31 13F AMICUS THERAPEUTICS COM 03152W109 28,057,456 0 330,517 5.7402
2024-02-26 2023-12-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 28,057,456 364,539 1.32 398,135 18.23 8.8870
2024-02-14 2023-12-31 13F AMICUS THERAPEUTICS COM 03152W109 28,057,456 364,539 398,135 8.8831
2023-11-14 2023-09-30 13F AMICUS THERAPEUTICS COM 03152W109 27,692,917 30,000 0.11 336,746 -3.08 11.2327
2023-08-24 2023-06-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 27,662,917 0 0.00 347,446 13.26 10.0568
2023-08-14 2023-06-30 13F AMICUS THERAPEUTICS COM 03152W109 27,662,917 0 347,446 10.0726
2023-05-16 2023-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 27,662,917 20,000 0.07 306,782 -9.11 9.0576
2023-05-15 2023-03-31 13F AMICUS THERAPEUTICS COM 03152W109 27,662,917 20,000 306,782 7.9846
2023-02-14 2022-12-31 13F AMICUS THERAPEUTICS COM 03152W109 27,642,917 270,000 0.99 337,520 18.11 9.4778
2022-11-14 2022-09-30 13F AMICUS THERAPEUTICS COM 03152W109 27,372,917 477,385 1.77 285,773 -1.07 8.2937
2022-08-15 2022-06-30 13F AMICUS THERAPEUTICS COM 03152W109 26,895,532 -660,313 -2.40 288,858 10.69 9.0471
2022-05-16 2022-03-31 13F AMICUS THERAPEUTICS COM 03152W109 27,555,845 996,402 3.75 260,954 -14.93 5.2271
2022-05-04 2021-12-31 13F/A-2 AMICUS THERAPEUTICS COM 03152W109 26,559,443 0 0.00 306,762 20.94 4.7276
2022-04-13 2021-12-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 26,559,443 0 306,762 4.7362
2022-02-14 2021-12-31 13F AMICUS THERAPEUTICS COM 03152W109 26,559,443 0 306,762 4.7335
2021-12-03 2021-09-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 26,559,443 3,438,114 14.87 253,643 13.80 3.6843
2021-11-15 2021-09-30 13F AMICUS THERAPEUTICS COM 03152W109 26,559,443 3,438,114 253,643 3.6829
2021-08-17 2021-06-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 23,121,329 260,000 1.14 222,890 -1.32 2.8923
2021-08-16 2021-06-30 13F AMICUS THERAPEUTICS COM 03152W109 23,121,329 260,000 222,890 2.8981
2021-08-13 2021-03-31 13F/A-2 AMICUS THERAPEUTICS COM 03152W109 22,861,329 -2,250,719 -8.96 225,870 -61.05 2.8563
2021-06-10 2021-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 22,861,329 0 225,870 2.8490
2021-05-17 2021-03-31 13F AMICUS THERAPEUTICS COM 03152W109 22,861,329 -2,250,719 225,870 2.8544
2021-02-16 2020-12-31 13F AMICUS THERAPEUTICS COM 03152W109 25,112,048 -10,000 -0.04 579,837 63.46 6.2226
2020-11-16 2020-09-30 13F AMICUS THERAPEUTICS COM 03152W109 25,122,048 -60,316 -0.24 354,723 -6.59 5.1788
2020-08-17 2020-06-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 25,182,364 0 0.00 379,750 63.20 6.1537
2020-08-14 2020-06-30 13F AMICUS THERAPEUTICS COM 03152W109 25,182,364 0 379,750 6,168,267.4112
2020-05-18 2020-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 25,182,364 50,000 0.20 232,685 -4.94 6.0602
2020-05-15 2020-03-31 13F AMICUS THERAPEUTICS COM 03152W109 25,182,364 50,000 232,685 6,060,212.2331
2020-02-19 2019-12-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 25,132,364 522,664 2.12 244,789 24.03 4.8626
2020-02-14 2019-12-31 13F AMICUS THERAPEUTICS COM 03152W109 25,132,364 522,664 244,789 3,951,949.3689
2019-11-14 2019-09-30 13F AMICUS THERAPEUTICS COM 03152W109 24,609,700 3,100,214 14.41 197,369 -26.48 5.3173
2019-08-14 2019-06-30 13F AMICUS THERAPEUTICS COM 03152W109 21,509,486 -130,000 -0.60 268,438 -8.79 6.1597
2019-05-16 2019-03-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 21,639,486 915,062 4.42 294,297 53.52 8.3035
2019-05-15 2019-03-31 13F AMICUS THERAPEUTICS COM 03152W109 21,639,486 294,297
2019-02-14 2018-12-31 13F AMICUS THERAPEUTICS COM 03152W109 20,724,424 30,000 0.14 191,701 -23.38 7.2957
2018-11-14 2018-09-30 13F AMICUS THERAPEUTICS COM 03152W109 20,694,424 670,000 3.35 250,196 -20.01 6.6900
2018-11-01 2018-06-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 20,024,424 0 0.00 312,782 3.86 8.2000
2018-08-14 2018-06-30 13F AMICUS THERAPEUTICS COM 03152W109 20,024,424 0 312,782
2018-05-15 2018-03-31 13F AMICUS THERAPEUTICS COM 03152W109 20,024,424 2,135,827 11.94 301,167 17.00 8.4355
2018-02-14 2017-12-31 13F AMICUS THERAPEUTICS COM 03152W109 17,888,597 0 0.00 257,417 -4.58 8.5329
2017-11-14 2017-09-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 17,888,597 591,925 3.42 269,760 54.88 10.3059
2017-11-14 2017-09-30 13F AMICUS THERAPEUTICS COM 03152W109 17,888,597 269,760
2017-08-14 2017-06-30 13F AMICUS THERAPEUTICS COM 03152W109 17,296,672 0 0.00 174,178 41.23 8.7647
2017-05-15 2017-03-31 13F AMICUS THERAPEUTICS SHARES COM 03152W109 17,296,672 0 0.00 123,325 43.46 7.0251
2017-05-02 2016-12-31 13F/A-3 AMICUS THERAPEUTICS COM 03152W109 17,296,672 3,180,028 22.53 85,964 -17.71 6.1130
2017-03-20 2016-12-31 13F/A-2 AMICUS THERAPEUTICS COM 03152W109 17,296,672 0 85,964 6.1173
2017-03-09 2016-12-31 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 17,296,672 0 85,964 6.1173
2017-02-14 2016-12-31 13F AMICUS THERAPEUTICS COM 03152W109 17,296,672 85,964
2016-11-14 2016-09-30 13F AMICUS THERAPEUTICS Common Stock 03152W109 14,116,644 -1,122,800 -7.37 104,463 25.55 6.7429
2016-08-11 2016-06-30 13F AMICUS COM 03152W109 15,239,444 0 0.00 83,207 -35.38 5.7683
2016-05-16 2016-03-31 13F AMICUS THERAPEUTICS COM 03152W109 15,239,444 0 0.00 128,773 -12.89 11.2948
2016-02-16 2015-12-31 13F AMICUS THERAPEUTICS COM 03152W109 15,239,444 800,000 5.54 147,823 -15.83 10.9367
2015-11-17 2015-09-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 14,439,444 0 0.00 175,633 -14.04 14.0275
2015-11-16 2015-09-30 13F AMICUS THERAPEUTICS COM 03152W109 14,439,444 175,633
2015-08-14 2015-06-30 13F AMICUS THERAPEUTICS COM 03152W109 14,439,444 0 0.00 204,318 30.06 12.3036
2015-05-15 2015-03-31 13F AMICUS THERAPEUTICS COM 03152W109 14,439,444 0 0.00 157,101 30.77 12.2086
2015-02-17 2014-12-31 13F AMICUS THERAPEUTICS COM 03152W109 14,439,444 2,100,000 17.02 120,136 63.63 10.0748
2014-11-17 2014-09-30 13F/A-2 AMICUS THERAPEUTICS COM 03152W109 12,339,444 0 0.00 73,420 78.14 7.4311
2014-11-17 2014-09-30 13F/A-1 AMICUS THERAPEUTICS COM 03152W109 12,339,444 0 73,420 7.8836
2014-11-14 2014-09-30 13F AMICUS THERAPEUTICS COM 03152W109 12,339,444 73,420
2014-08-14 2014-06-30 13F AMICUS THERAPEUTICS COM 03152W109 12,339,444 11,373,144 1,176.98 41,214 1,960.70 4.0433
2014-05-15 2014-03-31 13F AMICUS THERAPEUTICS COM 03152W109 966,300 966,300 2,000 0.2102
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.