Castle Biosciences, Inc.
US ˙ NasdaqGM ˙ US14843C1053

SecurityCSTL / Castle Biosciences, Inc.
InstitutionSignaturefd, Llc
Latest Disclosed Ownership45 shares
Latest Disclosed Value $ 1,105
Signaturefd, Llc ownership in CSTL / Castle Biosciences, Inc.

On April 7, 2026 - Signaturefd, Llc filed a 13F-HR form disclosing ownership of 45 shares of Castle Biosciences, Inc. (US:CSTL) valued at $1,105 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 20, 2026 disclosing 45 shares of Castle Biosciences, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $945 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-07 2026-03-31 13F CASTLE BIOSCIENCES COM 14843C105 45 0 0.00 1 0.00 0.0000
2026-01-20 2025-12-31 13F CASTLE BIOSCIENCES COM 14843C105 45 0 0.00 2 0.00 0.0000
2025-10-21 2025-09-30 13F CASTLE BIOSCIENCES COM 14843C105 45 0 0.00 1 0.0000
2025-07-16 2025-06-30 13F CASTLE BIOSCIENCES COM 14843C105 45 45 1 0.0000
2024-02-01 2023-12-31 13F CASTLE BIOSCIENCES COM 14843C105 0 -28,358 -100.00 0 -100.00
2023-11-03 2023-09-30 13F CASTLE BIOSCIENCES COM 14843C105 28,358 -32 -0.11 479 22.88 0.0125
2023-08-01 2023-06-30 13F CASTLE BIOSCIENCES COM 14843C105 28,390 8,982 46.28 390 -11.59 0.0099
2023-04-28 2023-03-31 13F CASTLE BIOSCIENCES COM 14843C105 19,408 11 0.06 441 -3.51 0.0120
2023-01-30 2022-12-31 13F CASTLE BIOSCIENCES COM 14843C105 19,397 0 0.00 457 -9.88 0.0133
2022-11-08 2022-09-30 13F CASTLE BIOSCIENCES COM 14843C105 19,397 0 0.00 506 18.78 0.0173
2022-08-10 2022-06-30 13F CASTLE BIOSCIENCES COM 14843C105 19,397 7,592 64.31 426 -19.62 0.0145
2022-05-02 2022-03-31 13F CASTLE BIOSCIENCES COM 14843C105 11,805 -7,610 -39.20 530 -36.30 0.0160
2022-01-25 2021-12-31 13F CASTLE BIOSCIENCES COM 14843C105 19,415 32 0.17 832 -35.45 0.0256
2021-10-28 2021-09-30 13F CASTLE BIOSCIENCES COM 14843C105 19,383 10 0.05 1,289 -9.29 0.0445
2021-07-26 2021-06-30 13F CASTLE BIOSCIENCES COM 14843C105 19,373 8 0.04 1,421 7.16 0.0567
2021-04-30 2021-03-31 13F CASTLE BIOSCIENCES COM 14843C105 19,365 240 1.25 1,326 3.27 0.0586
2021-02-11 2020-12-31 13F CASTLE BIOSCIENCES COM 14843C105 19,125 -13,000 -40.47 1,284 -22.32 0.0605
2020-11-03 2020-09-30 13F CASTLE BIOSCIENCES COM 14843C105 32,125 0 0.00 1,653 36.50 0.0885
2020-07-30 2020-06-30 13F CASTLE BIOSCIENCES COM 14843C105 32,125 5,993 22.93 1,211 55.46 0.0732
2020-04-23 2020-03-31 13F CASTLE BIOSCIENCES COM 14843C105 26,132 10,000 61.99 779 40.61 0.0673
2020-02-05 2019-12-31 13F CASTLE BIOSCIENCES COM 14843C105 16,132 16,132 554 0.0409
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.