Cerus Corporation
US ˙ NasdaqGM ˙ US1570851014

SecurityCERS / Cerus Corporation
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership3,731,151 shares
Latest Disclosed Value $ 6,790,694
D. E. Shaw & Co., Inc. reports 3.67% decrease in ownership of CERS / Cerus Corporation

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 3,731,151 shares of Cerus Corporation (US:CERS) valued at $6,790,695 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 3,873,371 shares of Cerus Corporation. This represents a change in shares of -3.67% during the quarter. The current value of the position is $9,924,862 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F CERUS COM 157085101 3,731,151 -142,220 -3.67 6,791 -14.90 0.0041
2026-02-17 2025-12-31 13F CERUS COM 157085101 3,873,371 54,319 1.42 7,979 31.41 0.0044
2025-11-14 2025-09-30 13F CERUS COM 157085101 3,819,052 66,948 1.78 6,072 14.78 0.0034
2025-08-14 2025-06-30 13F CERUS COM 157085101 3,752,104 -38,627 -1.02 5,290 0.40 0.0038
2025-05-15 2025-03-31 13F CERUS COM 157085101 3,790,731 361,798 10.55 5,269 -0.21 0.0047
2025-02-14 2024-12-31 13F CERUS COM 157085101 3,428,933 -220,300 -6.04 5,281 -16.84 0.0039
2024-11-14 2024-09-30 13F CERUS COM 157085101 3,649,233 205,234 5.96 6,350 4.75 0.0055
2024-08-14 2024-06-30 13F CERUS COM 157085101 3,443,999 149,610 4.54 6,061 -2.65 0.0057
2024-05-15 2024-03-31 13F CERUS COM 157085101 3,294,389 426,678 14.88 6,226 0.52 0.0053
2024-02-14 2023-12-31 13F CERUS COM 157085101 2,867,711 -295,075 -9.33 6,194 20.91 0.0054
2023-11-14 2023-09-30 13F CERUS COM 157085101 3,162,786 -144,183 -4.36 5,124 -37.03 0.0053
2023-08-14 2023-06-30 13F CERUS COM 157085101 3,306,969 475,137 16.78 8,135 -3.27 0.0083
2023-05-15 2023-03-31 13F CERUS COM 157085101 2,831,832 479,868 20.40 8,411 -2.03 0.0090
2023-02-14 2022-12-31 13F CERUS COM 157085101 2,351,964 -522,799 -18.19 8,585 -17.05 0.0095
2022-11-14 2022-09-30 13F CERUS COM 157085101 2,874,763 92,683 3.33 10,349 -29.68 0.0124
2022-08-15 2022-06-30 13F CERUS COM 157085101 2,782,080 40,943 1.49 14,717 -2.21 0.0173
2022-05-16 2022-03-31 13F CERUS COM 157085101 2,741,137 295,765 12.09 15,049 -9.63 0.0141
2022-02-14 2021-12-31 13F CERUS COM 157085101 2,445,372 786,686 47.43 16,653 64.86 0.0138
2021-11-15 2021-09-30 13F CERUS COM 157085101 1,658,686 545,676 49.03 10,101 53.56 0.0091
2021-08-16 2021-06-30 13F CERUS COM 157085101 1,113,010 343,602 44.66 6,578 42.26 0.0057
2021-05-17 2021-03-31 13F CERUS COM 157085101 769,408 -1,158,476 -60.09 4,624 -65.34 0.0045
2021-02-16 2020-12-31 13F CERUS COM 157085101 1,927,884 234,611 13.86 13,341 25.86 0.0119
2020-11-16 2020-09-30 13F CERUS COM 157085101 1,693,273 -273,058 -13.89 10,600 -18.32 0.0108
2020-08-14 2020-06-30 13F CERUS COM 157085101 1,966,331 297,692 17.84 12,978 67.24 0.0155
2020-05-15 2020-03-31 13F CERUS COM 157085101 1,668,639 -1,045,519 -38.52 7,760 -32.25 0.0121
2020-02-14 2019-12-31 13F CERUS COM 157085101 2,714,158 727,056 36.59 11,454 11.81 0.0131
2019-11-14 2019-09-30 13F CERUS COM 157085101 1,987,102 483,602 32.17 10,244 21.25 0.0126
2019-08-14 2019-06-30 13F CERUS COM 157085101 1,503,500 896,994 147.90 8,449 123.58 0.0105
2019-05-15 2019-03-31 13F CERUS COM 157085101 606,506 258,896 74.48 3,779 114.47 0.0049
2019-02-14 2018-12-31 13F CERUS COM 157085101 347,610 -496,191 -58.80 1,762 -71.04 0.0024
2018-11-14 2018-09-30 13F CERUS COM 157085101 843,801 -211,099 -20.01 6,084 -13.53 0.0073
2018-08-14 2018-06-30 13F CERUS COM 157085101 1,054,900 544,903 106.84 7,036 151.83 0.0092
2018-05-15 2018-03-31 13F CERUS COM 157085101 509,997 -158,598 -23.72 2,794 23.63 0.0038
2018-02-14 2017-12-31 13F CERUS COM 157085101 668,595 194,397 40.99 2,260 74.65 0.0031
2017-11-14 2017-09-30 13F CERUS COM 157085101 474,198 334,424 239.26 1,294 268.66 0.0020
2017-08-14 2017-06-30 13F CERUS COM 157085101 139,774 67,761 94.10 351 9.69 0.0006
2017-05-15 2017-03-31 13F CERUS COM 157085101 72,013 -197,638 -73.29 320 -72.72 0.0006
2017-02-14 2016-12-31 13F CERUS COM 157085101 269,651 269,651 0.00 1,173 0.0020
2016-08-15 2016-06-30 13F CERUS COM 157085101 0 -84,199 -100.00 0 -100.00
2016-05-16 2016-03-31 13F CERUS COM 157085101 84,199 -4,841 -5.44 499 -11.37 0.0009
2016-02-16 2015-12-31 13F CERUS COM 157085101 89,040 89,040 0.00 563 0.0008
2015-11-16 2015-09-30 13F CERUS COM 157085101 0 0 0 0.0000
2015-05-15 2015-03-31 13F CERUS COM 157085101 0 -123,620 -100.00 0 -100.00
2015-02-17 2014-12-31 13F CERUS COM 157085101 123,620 87,933 246.40 771 439.16 0.0010
2014-11-14 2014-09-30 13F CERUS COM 157085101 35,687 35,687 21.82 143 -27.41 0.0002
2014-02-14 2013-12-31 13F CERUS COM 157085101 0 -29,294 -100.00 0 -100.00
2013-11-20 2013-09-30 13F/A-1 CERUS COM 157085101 29,294 -17,514 -37.42 197 -4.83 0.0003
2013-11-14 2013-09-30 13F CERUS COM 157085101 29,294 197
2013-08-14 2013-06-30 13F CERUS COM 157085101 46,808 46,808 207 0.0004
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.