CareDx, Inc.
US ˙ NasdaqGM ˙ US14167L1035

SecurityCDNA / CareDx, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership2,737,752 shares
Ownership 5.30%
State Street Corp ownership in CDNA / CareDx, Inc.

2026-02-09 - State Street Corp has filed an SCHEDULE 13G form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,737,752 shares of CareDx, Inc. (US:CDNA). This represents 5.3 percent ownership of the company. In their previous filing dated 2024-10-17 , State Street Corp had reported owning 2,036,089 shares, indicating an increase of 34.46 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date		Effective
Date		Form Prev
Shares		 Latest
Shares		 ΔShares
(Percent)		 Ownership
(Percent)		 ΔOwnership
(Percent)
2026-02-09 2026-02-09 13G 2,036,089 2,737,752 34.46 5.30 35.90
2024-10-17 2024-10-17 13G/A 2,796,267 2,036,089 -27.19 3.90 -24.56
2024-01-10 2024-01-10 13G/A 5,747,244 2,796,267 -51.35 5.17 -51.86
2023-01-10 2023-01-10 13G/A 1,851,855 5,747,244 210.35 10.74 185.64
2021-02-12 2021-02-12 13G/A 2,564,843 1,851,855 -27.80 3.76 -37.75
2020-02-13 2020-02-13 13G 2,564,843 6.04

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F CAREDX COM 14167L103 2,760,385 22,633 0.83 47,920 -7.09 0.0017
2026-02-13 2025-12-31 13F CAREDX COM 14167L103 2,737,752 171,303 6.67 51,579 38.22 0.0017
2025-11-14 2025-09-30 13F CAREDX COM 14167L103 2,566,449 386,304 17.72 37,316 -12.40 0.0013
2025-08-14 2025-06-30 13F CAREDX COM 14167L103 2,180,145 -304,455 -12.25 42,600 -3.40 0.0016
2025-05-15 2025-03-31 13F CAREDX COM 14167L103 2,484,600 -174,499 -6.56 44,102 -22.54 0.0018
2025-02-14 2024-12-31 13F CAREDX COM 14167L103 2,659,099 623,010 30.60 56,931 -10.45 0.0022
2024-11-14 2024-09-30 13F CAREDX COM 14167L103 2,036,089 -71,741 -3.40 63,577 94.22 0.0026
2024-08-14 2024-06-30 13F CAREDX COM 14167L103 2,107,830 -2,088,510 -49.77 32,735 -26.34 0.0014
2024-05-15 2024-03-31 13F CAREDX COM 14167L103 4,196,340 1,400,073 50.07 44,439 32.44 0.0020
2024-02-14 2023-12-31 13F CAREDX COM 14167L103 2,796,267 -912,881 -24.61 33,555 29.24 0.0016
2023-11-14 2023-09-30 13F CAREDX COM 14167L103 3,709,148 -474,880 -11.35 25,964 -26.99 0.0014
2023-08-14 2023-06-30 13F CAREDX COM 14167L103 4,184,028 -694,008 -14.23 35,564 -20.23 0.0019
2023-05-15 2023-03-31 13F CAREDX COM 14167L103 4,878,036 -869,208 -15.12 44,585 -32.01 0.0025
2023-05-15 2022-12-31 13F/A-99 CAREDX COM 14167L103 5,747,244 1,501,219 35.36 65,576 -9.26 0.0039
2023-05-15 2022-12-31 13F CAREDX COM 14167L103 5,747,244 1,501,219 65,576 0.0039
2022-11-15 2022-09-30 13F CAREDX COM 14167L103 4,246,025 31,345 0.74 72,267 -20.17 0.0046
2022-08-15 2022-06-30 13F CAREDX COM 14167L103 4,214,680 1,174,094 38.61 90,531 -19.51 0.0054
2022-05-16 2022-03-31 13F CAREDX COM 14167L103 3,040,586 745,779 32.50 112,471 7.76 0.0056
2022-02-14 2021-12-31 13F CAREDX COM 14167L103 2,294,807 509,420 28.53 104,368 -7.75 0.0049
2021-11-15 2021-09-30 13F CAREDX COM 14167L103 1,785,387 300,364 20.23 113,140 -16.75 0.0060
2021-08-16 2021-06-30 13F CAREDX COM 14167L103 1,485,023 -179,183 -10.77 135,909 19.94 0.0072
2021-07-09 2021-03-31 13F/A-1 CAREDX COM 14167L103 1,664,206 -187,649 -10.13 113,316 -15.54 0.0065
2021-05-17 2021-03-31 13F CAREDX COM 14167L103 1,664,206 -187,649 113,316 0.0065
2021-02-16 2020-12-31 13F CAREDX COM 14167L103 1,851,855 -267,586 -12.63 134,167 66.85 0.0082
2020-11-10 2020-09-30 13F CAREDX COM 14167L103 2,119,441 -27,054 -1.26 80,412 5.74 0.0055
2020-08-14 2020-06-30 13F CAREDX COM 14167L103 2,146,495 -426,271 -16.57 76,050 35.41 0.0055
2020-06-19 2020-03-31 13F/A-1 CAREDX COM 14167L103 2,572,766 7,923 0.31 56,163 1.52 0.0049
2020-05-11 2020-03-31 13F CAREDX COM 14167L103 2,572,766 7,923 56,163 4,932.2423
2020-02-06 2019-12-31 13F CAREDX COM 14167L103 2,564,843 -314,506 -10.92 55,324 -15.02 0.0038
2019-11-14 2019-09-30 13F CAREDX COM 14167L103 2,879,349 609,930 26.88 65,102 -20.29 0.0049
2019-08-14 2019-06-30 13F CAREDX COM 14167L103 2,269,419 425,842 23.10 81,676 40.55 0.0061
2019-05-15 2019-03-31 13F CAREDX COM 14167L103 1,843,577 -31,384 -1.67 58,110 23.28 0.0045
2019-02-12 2018-12-31 13F CAREDX COM 14167L103 1,874,961 624,318 49.92 47,137 30.63 0.0043
2018-11-09 2018-09-30 13F CAREDX Common equity shares 14167L103 1,250,643 724,214 137.57 36,084 459.62 0.0028
2018-08-14 2018-06-30 13F CAREDX Common equity shares 14167L103 526,429 516,329 5,112.17 6,448 7,860.49 0.0005
2018-05-15 2018-03-31 13F CAREDX Common equity shares 14167L103 10,100 10,100 81 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.