Axogen, Inc.
US ˙ NasdaqCM ˙ US05463X1063

SecurityAXGN / Axogen, Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership265,009 shares
Latest Disclosed Value $ 8,779,748
D. E. Shaw & Co., Inc. reports 64.75% increase in ownership of AXGN / Axogen, Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 265,009 shares of Axogen, Inc. (US:AXGN) valued at $8,779,748 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 160,852 shares of Axogen, Inc.. This represents a change in shares of 64.75% during the quarter. The current value of the position is $10,767,316 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F AXOGEN COM 05463X106 265,009 104,157 64.75 8,780 66.77 0.0053
2026-02-17 2025-12-31 13F AXOGEN COM 05463X106 160,852 -13,292 -7.63 5,265 69.48 0.0029
2025-11-14 2025-09-30 13F AXOGEN COM 05463X106 174,144 -274,289 -61.17 3,107 -36.16 0.0018
2025-08-14 2025-06-30 13F AXOGEN COM 05463X106 448,433 -113,993 -20.27 4,865 -53.24 0.0034
2025-05-15 2025-03-31 13F AXOGEN COM 05463X106 562,426 74,120 15.18 10,405 29.29 0.0093
2025-02-14 2024-12-31 13F AXOGEN COM 05463X106 488,306 -146,038 -23.02 8,047 -9.51 0.0059
2024-11-14 2024-09-30 13F AXOGEN COM 05463X106 634,344 25,759 4.23 8,894 101.84 0.0076
2024-08-14 2024-06-30 13F AXOGEN COM 05463X106 608,585 2,030 0.33 4,406 -9.97 0.0041
2024-05-15 2024-03-31 13F AXOGEN COM 05463X106 606,555 -4,433 -0.73 4,895 17.28 0.0042
2024-02-14 2023-12-31 13F AXOGEN COM 05463X106 610,988 35,543 6.18 4,173 45.05 0.0036
2023-11-14 2023-09-30 13F AXOGEN COM 05463X106 575,445 -139,357 -19.50 2,877 -55.91 0.0030
2023-08-14 2023-06-30 13F AXOGEN COM 05463X106 714,802 40,614 6.02 6,526 2.43 0.0067
2023-05-15 2023-03-31 13F AXOGEN COM 05463X106 674,188 -35,509 -5.00 6,371 -10.04 0.0068
2023-02-14 2022-12-31 13F AXOGEN COM 05463X106 709,697 51,860 7.88 7,083 -9.68 0.0078
2022-11-14 2022-09-30 13F AXOGEN COM 05463X106 657,837 -78,563 -10.67 7,841 30.01 0.0094
2022-08-15 2022-06-30 13F AXOGEN COM 05463X106 736,400 -71,991 -8.91 6,031 -6.04 0.0071
2022-05-16 2022-03-31 13F AXOGEN COM 05463X106 808,391 18,282 2.31 6,419 -13.29 0.0060
2022-02-14 2021-12-31 13F AXOGEN COM 05463X106 790,109 180,185 29.54 7,403 -23.18 0.0061
2021-11-15 2021-09-30 13F AXOGEN COM 05463X106 609,924 11,159 1.86 9,637 -25.52 0.0087
2021-08-16 2021-06-30 13F AXOGEN COM 05463X106 598,765 -13,867 -2.26 12,939 4.25 0.0112
2021-05-17 2021-03-31 13F AXOGEN COM 05463X106 612,632 -44,114 -6.72 12,412 5.58 0.0120
2021-02-16 2020-12-31 13F AXOGEN COM 05463X106 656,746 -99,593 -13.17 11,756 33.65 0.0105
2020-11-16 2020-09-30 13F AXOGEN COM 05463X106 756,339 -3,891 -0.51 8,796 25.21 0.0090
2020-08-14 2020-06-30 13F AXOGEN COM 05463X106 760,230 46,489 6.51 7,025 -5.36 0.0084
2020-05-15 2020-03-31 13F AXOGEN COM 05463X106 713,741 -193,981 -21.37 7,423 -54.29 0.0116
2020-02-14 2019-12-31 13F AXOGEN COM 05463X106 907,722 90,406 11.06 16,239 59.21 0.0186
2019-11-14 2019-09-30 13F AXOGEN COM 05463X106 817,316 216,198 35.97 10,200 -14.30 0.0126
2019-08-14 2019-06-30 13F AXOGEN COM 05463X106 601,118 284,479 89.84 11,902 78.49 0.0148
2019-05-15 2019-03-31 13F AXOGEN COM 05463X106 316,639 160,318 102.56 6,668 108.77 0.0086
2019-02-14 2018-12-31 13F AXOGEN COM 05463X106 156,321 156,321 3,194 0.0044
2018-11-14 2018-09-30 13F AXOGEN COM 05463X106 0 -16,519 -100.00 0 -100.00
2018-08-14 2018-06-30 13F AXOGEN COM 05463X106 16,519 4,623 38.86 830 91.24 0.0011
2018-05-15 2018-03-31 13F AXOGEN COM 05463X106 11,896 11,896 434 0.0006
2018-02-14 2017-12-31 13F AXOGEN COM 05463X106 0 -24,207 -100.00 0 -100.00
2017-11-14 2017-09-30 13F AXOGEN COM 05463X106 24,207 24,207 468 0.0007
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.