Applied Therapeutics, Inc.
US ˙ NasdaqCM ˙ US03828A1016
DETTE SYMBOL ER IKKE LÆNGERE AKTIVT

SecurityAPLT / Applied Therapeutics, Inc.
InstitutionVanguard Group Inc
Latest Disclosed Ownership4,734,013 shares
Ownership 3.34%
Vanguard Group Inc ownership in APLT / Applied Therapeutics, Inc.

2025-07-29 - Vanguard Group Inc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 4,734,013 shares of Applied Therapeutics, Inc. (US:APLT). This represents 3.34 percent ownership of the company. In their previous filing dated 2025-04-30 , Vanguard Group Inc had reported owning 5,889,193 shares, indicating a decrease of -19.62 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2025-07-29 2025-07-29 13G/A 5,889,193 4,734,013 -19.62 3.34 -33.99
2025-04-30 2025-04-30 13G 5,889,193 5.06

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F APPLIED THERAPEUTICS COM 03828A101 6,353,018 1,250,329 24.50 635 -79.43 0.0000
2025-11-07 2025-09-30 13F APPLIED THERAPEUTICS COM 03828A101 5,102,689 368,676 7.79 3,087 109.71 0.0000
2025-08-11 2025-06-30 13F APPLIED THERAPEUTICS COM 03828A101 4,734,013 -1,155,180 -19.62 1,472 -48.87 0.0000
2025-05-09 2025-03-31 13F APPLIED THERAPEUTICS COM 03828A101 5,889,193 340,962 6.15 2,880 -39.38 0.0001
2025-02-11 2024-12-31 13F APPLIED THERAPEUTICS COM 03828A101 5,548,231 305,282 5.82 4,749 -89.34 0.0001
2024-11-13 2024-09-30 13F APPLIED THERAPEUTICS COM 03828A101 5,242,949 -79,511 -1.49 44,565 79.30 0.0008
2024-08-13 2024-06-30 13F APPLIED THERAPEUTICS COM 03828A101 5,322,460 2,312,170 76.81 24,856 21.43 0.0005
2024-05-10 2024-03-31 13F APPLIED THERAPEUTICS COM 03828A101 3,010,290 -220,191 -6.82 20,470 89.14 0.0004
2024-03-11 2023-12-31 13F/A-1 APPLIED THERAPEUTICS COM 03828A101 3,230,481 1,801,827 126.12 10,822 204.25 0.0002
2024-02-14 2023-12-31 13F APPLIED THERAPEUTICS COM 03828A101 3,230,481 1,801,827 10,822 0.0002
2023-12-18 2023-09-30 13F/A-1 APPLIED THERAPEUTICS COM 03828A101 1,428,654 431,652 43.29 3,557 178.76 0.0001
2023-11-14 2023-09-30 13F APPLIED THERAPEUTICS COM 03828A101 1,428,654 431,652 3,557 0.0000
2023-08-14 2023-06-30 13F APPLIED THERAPEUTICS COM 03828A101 997,002 141,847 16.59 1,276 84.13 0.0000
2023-07-14 2023-03-31 13F/A-1 APPLIED THERAPEUTICS COM 03828A101 855,155 58,593 7.36 694 14.55 0.0000
2023-05-15 2023-03-31 13F APPLIED THERAPEUTICS COM 03828A101 855,155 58,593 694 0.0000
2023-02-10 2022-12-31 13F APPLIED THERAPEUTICS COM 03828A101 796,562 343,299 75.74 605 43.36 0.0000
2022-11-14 2022-09-30 13F APPLIED THERAPEUTICS COM 03828A101 453,263 -60,956 -11.85 422 -13.52 0.0000
2022-08-12 2022-06-30 13F APPLIED THERAPEUTICS COM 03828A101 514,219 -96,648 -15.82 488 -62.11 0.0000
2022-05-13 2022-03-31 13F APPLIED THERAPEUTICS COM 03828A101 610,867 -240,271 -28.23 1,288 -83.09 0.0000
2022-02-14 2021-12-31 13F APPLIED THERAPEUTICS COM 03828A101 851,138 839 0.10 7,618 -46.03 0.0002
2021-11-12 2021-09-30 13F APPLIED THERAPEUTICS COM 03828A101 850,299 5,417 0.64 14,114 -19.61 0.0004
2021-08-13 2021-06-30 13F APPLIED THERAPEUTICS COM 03828A101 844,882 10,713 1.28 17,557 12.23 0.0004
2021-05-14 2021-03-31 13F APPLIED THERAPEUTICS COM 03828A101 834,169 152,605 22.39 15,644 4.29 0.0004
2021-02-12 2020-12-31 13F APPLIED THERAPEUTICS COM 03828A101 681,564 887 0.13 15,001 6.15 0.0004
2020-11-16 2020-09-30 13F APPLIED THERAPEUTICS COM 03828A101 680,677 65,157 10.59 14,132 -36.49 0.0005
2020-08-14 2020-06-30 13F APPLIED THERAPEUTICS COM 03828A101 615,520 67,462 12.31 22,251 24.19 0.0008
2020-05-15 2020-03-31 13F APPLIED THERAPEUTICS COM 03828A101 548,058 208,162 61.24 17,917 93.22 0.0008
2020-02-14 2019-12-31 13F APPLIED THERAPEUTICS COM 03828A101 339,896 304,932 872.13 9,273 2,314.84 0.0003
2019-11-14 2019-09-30 13F APPLIED THERAPEUTICS COM 03828A101 34,964 34,964 384 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.