| Deler fremragende | 30,790,388 shares |
| Insideraktier | 3.154.635 shares |
| Insider ejerskab | 10,25 % |
| Total Insiders | 41 |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Insiderhandelsdiagram
Ethos Technologies Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Srinivas Akkaraju
10% Owner -
|
1.866.126 | 133.295 | |
|
Alta Partners VIII, L.P.
10% Owner -
|
1.778.064 | 127.005 | |
| Ashraf Amanullah See Remarks - [O] | 26.264 | 1.876 | |
| Ashlock Melissa A. See Remarks - [O] | 136.328 | 9.738 | |
|
James C Blair
Director, 10% Owner -
[D]
|
20.000 | 129.130 | |
| Kelly Blackburn See Remarks - [O] | 558 | 40 | |
| Stan Blackburn - | 23.908 | 1.708 | |
| John T Blake Senior Vice President, Finance - [O] | 1.932 | 138 | |
| Jill Marie Broadfoot Chief Financial Officer - [O] | 37.296 | 37.296 | |
|
Chp Ii Lp
10% Owner -
|
1.758.158 | 125.583 | |
| John K Clarke Director - [D] | 19.797 | 19.797 | |
| Frederic Chereau COO & President - [O] | 25.734 | 1.838 | |
| Chrzanowski Holly D. See Remarks - [O] | 3.770 | 269 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Timothy P Coughlin Director - [D] | 56.000 | 56.000 | |
| Andrew Cubitt | 25.000 | ||
|
Associates Domain
10% Owner -
|
18.858 | 1.347 | |
|
DP VIII Associates, L.P.
10% Owner -
|
13.414 | 958 | |
|
Domain Partners VIII, L.P.
10% Owner -
|
1.807.820 | 129.130 | |
|
EcoR1 Capital Fund Qualified, L.P.
10% Owner -
|
0 | 0 | |
| Kathryn E Falberg Director - [D] | 25.144 | 1.796 | |
|
James E Flynn
10% Owner -
|
255.764 | 18.269 | |
| Mark Alan Goldberg | 20.000 | ||
| Marcy Graham | 12.023 | ||
| Jane A Gross Director - [D] | 9.750 | 9.750 | |
| Hatfield Jeffrey S. | 1.428 | ||
|
Kamdar Kim P.
10% Owner -
|
18.858 | 1.347 | |
| David John King | 150.000 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Nancy Krueger General Counsel - [O] | 33.124 | 33.124 | |
| Svetlana Lucas Director - [D] | 6.000 | 6.000 | |
| John Mendlein Director - [D] | 615.382 | 43.956 | |
| Grove Matsuoka See Remarks - [O] | 12.412 | 887 | |
| McKew John C. | 40.000 | ||
| Amir Nashat Director - [D] | 17.638 | 1.260 | |
|
Polaris Venture Management Co. V, L.L.C.
10% Owner -
|
17.638 | 1.260 | |
| Fred Ramsdell | 5.393 | ||
| Ravindran Sanuj K. | 40.000 | ||
| Paul Schimmel Director - [D] | 2.101.056 | 2.101.056 | |
| Sanjay Shukla President and CEO, Director - [D] [O] | 153.553 | 153.553 | |
|
Sofinnova Venture Partners IX, L.P.
10% Owner -
|
1.866.126 | 133.295 | |
| Weiner David M. Chief Medical Officer - [O] | 10.056 | 718 | |
| Sara Zaknoen Director - [D] | 6.000 | 6.000 |
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i LIFE / Ethos Technologies Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i LIFE / Ethos Technologies Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-02-04 | 2026-02-04 | 4 | Shukla Sanjay | ATYR | Common Stock | D | 0,9760 | -3.745 | -4 | 153.553 | ||||
| 2026-02-04 | 2026-02-03 | 4 | Shukla Sanjay | ATYR | Common Stock | D | 10.375 | 157.298 | ||||||
| 2026-02-04 | 2026-02-04 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 0,9760 | -1.558 | -2 | 37.296 | ||||
| 2026-02-04 | 2026-02-03 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 3.750 | 38.854 | ||||||
| 2026-02-04 | 2026-02-04 | 4 | Krueger Nancy | ATYR | Common Stock | D | 0,9761 | -1.118 | -1 | 33.124 | ||||
| 2026-02-04 | 2026-02-03 | 4 | Krueger Nancy | ATYR | Common Stock | D | 2.687 | 34.242 | ||||||
| 2025-10-09 | 2025-10-09 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 0,9414 | 317.999 | 299 | 1.413.023 | ||||
| 2025-10-09 | 2025-10-08 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 0,8980 | 682.001 | 612 | 1.095.024 | ||||
| 2025-03-17 | 2025-03-17 | 4 | Gross Jane A | ATYR | Common Stock | D | 4,0000 | 3.750 | 15 | 9.750 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Shukla Sanjay | ATYR | Common Stock | D | 10.375 | 146.923 | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 3,7800 | -1.254 | -5 | 31.763 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 3.750 | 33.017 | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Krueger Nancy | ATYR | Common Stock | D | 3,7800 | -899 | -3 | 26.555 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Krueger Nancy | ATYR | Common Stock | D | 2.687 | 27.454 | ||||||
| 2024-07-24 | 2024-07-24 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,9319 | 52.300 | 101 | 413.023 | ||||
| 2024-07-24 | 2024-07-23 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,8163 | 6.648 | 12 | 360.723 | ||||
| 2024-07-24 | 2024-07-22 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,7417 | 41.052 | 72 | 354.075 | ||||
| 2024-06-06 | 2024-06-05 | 4 | Krueger Nancy | ATYR | Common Stock | D | 1,8552 | 5.000 | 9 | 22.267 | ||||
| 2024-06-03 | 2024-05-30 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | 1,7500 | 50.000 | 88 | 56.000 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 1,7900 | 5.000 | 9 | 27.960 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,8070 | 20.000 | 36 | 136.548 | ||||
| 2024-02-06 | 2024-02-05 | 4 | Shukla Sanjay | LIFE | Common stock | D | 10.375 | 116.548 | ||||||
| 2024-02-06 | 2024-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 1,6900 | -1.590 | -3 | 20.821 | ||||
| 2024-02-06 | 2024-02-05 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 3.750 | 22.411 | ||||||
| 2024-02-06 | 2024-02-05 | 4 | Krueger Nancy | LIFE | Common stock | D | 2.688 | 14.767 | ||||||
| 2023-12-12 | 2023-12-12 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1780 | 12.000 | 14 | 106.173 | ||||
| 2023-12-12 | 2023-12-11 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1700 | 3.000 | 4 | 94.173 | ||||
| 2023-11-13 | 2023-11-13 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1110 | 13.578 | 15 | 91.173 | ||||
| 2023-11-13 | 2023-11-10 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1380 | 1.422 | 2 | 77.595 | ||||
| 2023-08-01 | 2023-07-28 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,0149 | 15.000 | 30 | 76.173 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | 6.000 | 6.000 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | D | -6.000 | 0 | ||||||
| 2023-05-11 | 2023-05-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2500 | 200.000 | 450 | 313.023 | ||||
| 2023-04-28 | 2023-04-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | 6.000 | 19.797 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Coughlin Timothy P | LIFE | Common stock | D | 6.000 | 6.000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Lucas Svetlana | LIFE | Common stock | D | 6.000 | 6.000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | SCHIMMEL PAUL | LIFE | Common stock | D | 6.000 | 8.890 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Zaknoen Sara | LIFE | Common stock | D | 6.000 | 6.000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Gross Jane A | LIFE | Common stock | D | 6.000 | 6.000 | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Krueger Nancy | LIFE | Common stock | D | 2.688 | 7.079 | ||||||
| 2023-02-06 | 2023-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 2,3600 | -1.566 | -4 | 15.460 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 3.750 | 17.026 | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Shukla Sanjay | LIFE | Common stock | D | 10.375 | 61.173 | ||||||
| 2022-11-21 | 2022-11-21 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,1405 | 10.000 | 21 | 50.798 | ||||
| 2022-07-06 | 2022-07-01 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,8776 | 15.000 | 43 | 40.798 | ||||
| 2022-05-26 | 2022-05-24 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 88.097 | 88.097 | |||||
| 2022-05-26 | 2022-05-24 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 75.347 | 75.347 | |||||
| 2022-05-26 | 2022-05-24 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 516.280 | 516.280 | |||||
| 2022-04-28 | 2022-04-26 | 4 | CLARKE JOHN K | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | SCHIMMEL PAUL | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Coughlin Timothy P | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Zaknoen Sara | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Gross Jane A | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Lucas Svetlana | LIFE | Restricted Stock Units | D | 6.000 | 6.000 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Units | D | 15.000 | 15.000 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 30.000 | 30.000 | |||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | 10.750 | 10.750 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 21.500 | 21.500 | |||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Restricted Stock Units | D | 41.500 | 41.500 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 83.000 | 83.000 | |||||
| 2022-01-18 | 2022-01-13 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 6,7500 | 1.923 | 13 | 12.112 | ||||
| 2022-01-10 | 2022-01-07 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 6,7613 | 5.000 | 34 | 25.798 | ||||
| 2021-11-15 | 2021-11-15 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 8,5750 | 2.500 | 21 | 20.798 | ||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 250.000 | 679.143 | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | -250.000 | 2.890 | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 8,0000 | 250.000 | 2.000 | 252.890 | ||||
| 2021-05-25 | 2021-05-21 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,3400 | -2.500 | -11 | 108.083 | ||||
| 2021-05-25 | 2021-05-21 | 4 | Krueger Nancy | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 59.000 | 59.000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 207.000 | 207.000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 54.000 | 54.000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Zaknoen Sara | LIFE | Stock Option (right to buy) | D | 4,45 | 2.285 | 2.285 | |||||
| 2021-05-20 | 2021-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,9800 | 50.000 | 199 | 113.023 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 4,0100 | 10.000 | 40 | 18.298 | ||||
| 2021-04-29 | 2021-04-28 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 4,21 | 1.428 | 1.428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 4,21 | 1.428 | 1.428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 4,21 | 1.428 | 1.428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 4,21 | 1.428 | 1.428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 4,21 | 1.428 | 1.428 | |||||
| 2021-03-09 | 2021-02-04 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 112.469 | 112.469 | |||||
| 2021-03-09 | 2020-05-26 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 73.142 | 73.142 | |||||
| 2021-02-09 | 2021-02-09 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 7,6600 | -390 | -3 | 9.833 | ||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | -892 | 0 | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 892 | 10.223 | ||||||
| 2021-02-09 | 2021-02-09 | 4 | Shukla Sanjay | LIFE | Common stock | D | 7,6600 | -778 | -6 | 8.298 | ||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | -1.785 | 0 | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | 1.785 | 9.076 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 120.000 | 120.000 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 45.000 | 45.000 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 50.000 | 50.000 | |||||
| 2020-09-03 | 2020-09-02 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0100 | -7.260 | -29 | 110.583 | ||||
| 2020-09-03 | 2020-08-28 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0000 | -100 | -0 | 117.843 | ||||
| 2020-08-28 | 2020-08-27 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0900 | -5.440 | -22 | 117.943 | ||||
| 2020-08-28 | 2020-08-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,2960 | -2.200 | -9 | 123.383 | ||||
| 2020-06-23 | 2020-06-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 4,2200 | 1.850 | 8 | 9.153 | ||||
| 2020-06-23 | 2020-06-19 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 4,2700 | 6.000 | 26 | 7.291 | ||||
| 2020-05-28 | 2020-05-26 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 80.000 | 0 | |||||
| 2020-05-28 | 2020-05-26 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 30.000 | 30.000 | |||||
| 2020-05-28 | 2020-05-26 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 30.000 | 30.000 | |||||
| 2020-05-28 | 2020-05-20 | 4 | Krueger Nancy | LIFE | Common Stock | D | 3,6200 | -322 | -1 | 2.735 | ||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Unit | D | -892 | 0 | ||||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | 892 | 3.057 | ||||||
| 2020-05-22 | 2020-05-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,6390 | -8.447 | -31 | 429.143 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,65 | 1.428 | 1.428 | |||||
| 2020-02-11 | 2020-02-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 4,2500 | 254.000 | 1.080 | 437.590 | ||||
| 2020-02-07 | 2020-02-07 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 4,0300 | -375 | -2 | 7.125 | ||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | -893 | 893 | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 893 | 7.500 | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 23.359 | 23.359 | |||||
| 2020-02-07 | 2020-02-05 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 13.778 | 13.778 | |||||
| 2020-02-07 | 2020-02-07 | 4 | Shukla Sanjay | LIFE | Common stock | D | 4,0300 | -745 | -3 | 1.291 | ||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | -1.786 | 1.786 | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | 1.786 | 2.036 | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 39.327 | 39.327 | |||||
| 2019-07-02 | 2019-06-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 5,13 | 2.285 | 2.285 | |||||
| 2019-07-02 | 2019-06-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 5,13 | 2.285 | 2.285 | |||||
| 2019-05-20 | 2019-05-17 | 4 | Krueger Nancy | LIFE | Common Stock | D | 0,4501 | -4.651 | -2 | 25.348 | ||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | 0,00 | -12.500 | 12.500 | |||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | 12.500 | 29.999 | ||||||
| 2019-05-10 | 2019-05-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 0,58 | 20.000 | 20.000 | |||||
| 2019-04-16 | 2019-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,5410 | 1.848.428 | 1.000 | 2.570.242 | ||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29.998 | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29.998 | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29.998 | ||||||||
| 2019-02-08 | 2019-02-06 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 125.000 | 125.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | 25.000 | 25.000 | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 50.000 | 50.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | 50.000 | 50.000 | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 200.000 | 200.000 | |||||
| 2018-12-26 | 2018-12-21 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 0,4236 | 195.000 | 83 | 615.382 | ||||
| 2018-12-26 | 2018-12-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 0,4129 | 50.000 | 21 | 420.382 | ||||
| 2018-11-28 | 2018-11-26 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,5420 | 147.225 | 80 | 882.302 | ||||
| 2018-09-21 | 2018-09-20 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,8352 | 38.000 | 32 | 90.000 | ||||
| 2018-09-21 | 2018-09-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,8122 | 26.000 | 21 | 52.000 | ||||
| 2018-09-18 | 2018-09-14 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,7329 | 26.000 | 19 | 26.000 | ||||
| 2018-09-05 | 2018-09-04 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7571 | 20.749 | 16 | 735.077 | ||||
| 2018-09-05 | 2018-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7160 | 22.000 | 16 | 714.328 | ||||
| 2018-08-31 | 2018-08-30 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7559 | 89.275 | 67 | 692.328 | ||||
| 2018-08-31 | 2018-08-29 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7199 | 75.136 | 54 | 603.053 | ||||
| 2018-08-01 | 2018-07-30 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 0,82 | 200.000 | 200.000 | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | 0,00 | 3.333 | 3.333 | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3.333 | 26.264 | ||||||
| 2018-05-21 | 2018-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,9963 | 150.000 | 149 | 527.917 | ||||
| 2018-05-17 | 2018-05-15 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 1,35 | 20.000 | 20.000 | |||||
| 2018-05-16 | 2018-05-16 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 0,8111 | -2.733.231 | -2.217 | 0 | ||||
| 2018-05-16 | 2018-05-15 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 1,4268 | -121.294 | -173 | 2.733.231 | ||||
| 2018-05-16 | 2018-05-14 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 1,7167 | -354.791 | -609 | 2.854.525 | ||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23.908 | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23.908 | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23.908 | ||||||||
| 2018-02-08 | 2018-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 300.000 | 300.000 | |||||
| 2018-02-08 | 2018-02-08 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3,4000 | -1.402 | -5 | 1.932 | ||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | 0,00 | -3.334 | 6.666 | |||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3.334 | 3.334 | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 100.000 | 100.000 | |||||
| 2018-02-08 | 2018-02-08 | 4 | Blake John T | LIFE | Common Stock | D | 3,4000 | -1.402 | -5 | 1.932 | ||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Restricted Stock Units | D | 0,00 | -3.334 | 6.666 | |||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Common Stock | D | 3.334 | 3.334 | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 75.000 | 75.000 | |||||
| 2018-02-08 | 2018-02-06 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 150.000 | 150.000 | |||||
| 2018-01-02 | 2018-01-02 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 3,80 | 32.000 | 32.000 | |||||
| 2017-12-14 | 2017-11-13 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 3,9500 | -1.083 | -4 | 3.209.316 | ||||
| 2017-12-14 | 2017-11-10 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,0008 | -5.860 | -23 | 3.210.399 | ||||
| 2017-12-14 | 2017-11-09 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,1504 | -5.819 | -24 | 3.216.259 | ||||
| 2017-12-14 | 2017-11-08 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,3000 | -1.070 | -5 | 3.222.078 | ||||
| 2017-12-14 | 2017-11-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,8000 | 24.728 | 119 | 3.223.148 | ||||
| 2017-12-14 | 2017-10-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 5,0500 | 4.879 | 25 | 3.198.420 | ||||
| 2017-11-03 | 2017-11-01 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,00 | 450.000 | 450.000 | |||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 6.387.082 | ||||||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 6.387.082 | ||||||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Warrant to Purchase Common Stock | I | 4,64 | 35.376 | 35.376 | |||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,6500 | 94.336 | 250 | 377.917 | ||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Warrant to Purchase Common Stock | D | 4,64 | 14.151 | 14.151 | |||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 2,6500 | 37.736 | 100 | 367.883 | ||||
| 2017-05-11 | 3/A | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 11.805 | ||||||||
| 2017-05-11 | 2017-05-09 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 3,15 | 20.000 | 20.000 | |||||
| 2017-04-26 | 2017-04-24 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 124 | 0 | 327.647 | ||||
| 2017-04-20 | 2017-04-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 1.552 | 5 | 327.523 | ||||
| 2017-04-20 | 2017-04-18 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 1.000 | 3 | 325.971 | ||||
| 2017-04-10 | 2017-04-07 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,25 | 32.000 | 32.000 | |||||
| 2017-04-04 | 2017-04-03 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,50 | 32.000 | 32.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 65.000 | 65.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 40.000 | 40.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 20.000 | 20.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 185.000 | 185.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Restricted Stock Unit | D | 10.000 | 10.000 | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 55.000 | 55.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 65.000 | 65.000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Unit | D | 10.000 | 10.000 | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 35.000 | 35.000 | |||||
| 2016-12-22 | 2016-12-21 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2818 | 10.000 | 23 | 721.814 | ||||
| 2016-12-22 | 2016-12-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2740 | 15.000 | 34 | 711.814 | ||||
| 2016-12-21 | 2016-12-19 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 2,1980 | 69.000 | 152 | 324.971 | ||||
| 2016-12-21 | 2016-12-20 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 2,2499 | 11.000 | 25 | 11.000 | ||||
| 2016-12-19 | 2016-12-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,3973 | 10.000 | 24 | 696.814 | ||||
| 2016-12-19 | 2016-12-15 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,4978 | 40.000 | 100 | 686.814 | ||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 12.572 | 646.814 | ||||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | -12.572 | 40.440 | ||||||
| 2016-09-22 | 2016-09-21 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,29 | 145.000 | 145.000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 25.000 | 25.000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 19.000 | 19.000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 45.500 | 45.500 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 28.000 | 28.000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 27.500 | 27.500 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 20.000 | 20.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 3,33 | 18.000 | 18.000 | |||||
| 2016-05-11 | 2016-05-11 | 4 | Matsuoka Grove | LIFE | Common Stock | D | 3,0300 | 10.000 | 30 | 12.412 | ||||
| 2016-05-11 | 2016-05-09 | 4 | Matsuoka Grove | LIFE | Common Stock | D | 3,0800 | 2.412 | 7 | 2.412 | ||||
| 2016-05-03 | 2016-05-03 | 4 | Matsuoka Grove | LIFE | Stock Option (right to buy) | D | 3,67 | 145.000 | 145.000 | |||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 4,1434 | 32.600 | 135 | 53.012 | ||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 4,2196 | 33.619 | 142 | 283.581 | ||||
| 2016-04-14 | 2016-04-13 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,8500 | 9.835 | 38 | 249.962 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,5913 | 22.100 | 79 | 233.581 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,4481 | 5.300 | 18 | 211.481 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5921 | 5.259 | 19 | 17.831 | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,6999 | 6.546 | 24 | 240.127 | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,7512 | 2.581 | 10 | 20.412 | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,4481 | 5.300 | 18 | 220.231 | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5915 | 27.359 | 98 | 214.931 | ||||
| 2016-04-11 | 2016-04-08 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,2194 | 85.000 | 274 | 187.572 | ||||
| 2016-04-08 | 2016-04-07 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,1896 | 40.000 | 128 | 102.572 | ||||
| 2016-04-07 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,5200 | 2.500 | 9 | 250.971 | ||||
| 2016-04-07 | 2016-04-06 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,2000 | 25.000 | 80 | 62.572 | ||||
| 2016-04-06 | 2016-04-05 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5247 | 25.000 | 88 | 37.572 | ||||
| 2016-04-06 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,5500 | 2.500 | 9 | 248.471 | ||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | 7.000 | ||||||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | 7.000 | ||||||||
| 2016-04-01 | 2016-03-30 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,86 | 163.000 | 163.000 | |||||
| 2016-03-30 | 2016-03-28 | 4 | Blackburn Kelly | LIFE | Restricted Stock Unit | D | 21.600 | 21.600 | ||||||
| 2016-03-30 | 2016-03-28 | 4 | Cubitt Andrew | LIFE | Restricted Stock Unit | D | 13.000 | 13.000 | ||||||
| 2016-01-29 | 2016-01-27 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 20.000 | 20.000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 8.500 | 8.500 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 18.250 | 18.250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 20.000 | 20.000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | 6,14 | 4.250 | 4.250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 18.250 | 18.250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 8.500 | 8.500 | |||||
| 2016-01-29 | 2016-01-27 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 135.000 | 135.000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 6,14 | 19.428 | 19.428 | |||||
| 2016-01-29 | 2015-09-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | -11.925 | 634.242 | ||||||
| 2016-01-29 | 2016-01-27 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 40.000 | 40.000 | |||||
| 2016-01-06 | 2016-01-04 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 148.732 | 148.732 | |||||
| 2016-01-06 | 2016-01-04 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 25.913 | 25.913 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 10.831 | 10.831 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 12.023 | 12.023 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 16.874 | 16.874 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 14.829 | 14.829 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 5.038 | 5.038 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 5.754 | 5.754 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 26.470 | 26.470 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 29.659 | 29.659 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 10.750 | 10.750 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 153.000 | 153.000 | |||||
| 2015-10-30 | 2015-10-28 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 12,49 | 7.500 | 7.500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 5.393 | 5.393 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 12.000 | 12.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 65.070 | 65.070 | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 71.000 | 71.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 11.337 | 11.337 | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 23.000 | 23.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 4.739 | 4.739 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 17.000 | 17.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 5.260 | 5.260 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 28.000 | 28.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 7.382 | 7.382 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 23.000 | 23.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 6.488 | 6.488 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 24.000 | 24.000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 2.518 | 2.518 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 9.500 | 9.500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 11.581 | 11.581 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 45.500 | 45.500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 12.976 | 12.976 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 30.000 | 30.000 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 14,96 | 6.286 | 6.286 | |||||
| 2015-05-14 | 3/A | SCHIMMEL PAUL | LIFE | Common Stock | D | 12.572 | ||||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series E Redeemable Convertible Preferred Stock | I | -446.827 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | -15.031 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series C Redeemable Convertible Preferred Stock | I | -558.508 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -1.440.058 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B Redeemable Convertible Preferred Stock | I | -1.200.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series A Redeemable Convertible Preferred Stock | I | -525.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | -248.024 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 46.152 | 646.167 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 470.020 | 600.015 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 31.181 | 31.181 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -14.968.722 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | 14,0000 | 320.000 | 4.480 | 1.866.126 | ||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | 1.546.126 | 1.546.126 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series D Redeemable Convertible Preferred Stock | D | -21.122 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series C Redeemable Convertible Preferred Stock | D | -170.218 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 24.055 | 245.971 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series D Redeemable Convertible Preferred Stock | I | -1.536.787 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series C Redeemable Convertible Preferred Stock | I | -2.127.660 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -4.320.173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B Redeemable Convertible Preferred Stock | I | -3.600.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series A Redeemable Convertible Preferred Stock | I | -2.400.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series E Redeemable Convertible Preferred Stock | D | -893.655 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 1.758.158 | 1.758.158 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | 92.306 | 104.878 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | -893.655 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | D | -1.126.866 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | D | -4.361.703 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | -4.320.173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | D | -3.600.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | 92.306 | 1.778.064 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | 1.685.758 | 1.685.758 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series D Redeemable Convertible Preferred Stock | D | -1.536.787 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series C Redeemable Convertible Preferred Stock | D | -2.127.660 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | -4.320.173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B Redeemable Convertible Preferred Stock | D | -3.600.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series A Redeemable Convertible Preferred Stock | D | -2.400.000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Common Stock | D | 1.758.158 | 1.758.158 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -8.623 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -5.906 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -16.806 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -862.318 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -14.706 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -10.074 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -28.661 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -1.470.577 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -42.087 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -28.831 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -82.029 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -4.208.756 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -41.686 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -28.556 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -81.248 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -4.168.683 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -34.737 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -23.796 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -67.704 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -3.473.763 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 890 | 17.638 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 610 | 12.082 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 1.736 | 34.378 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 89.069 | 1.763.894 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 16.748 | 16.748 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 11.472 | 11.472 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 32.642 | 32.642 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 1.674.825 | 1.674.825 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -8.623 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -5.906 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -16.806 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | -862.318 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -14.706 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -10.074 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -28.661 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | -1.470.577 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -42.087 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -28.831 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -82.029 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | -4.208.756 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -41.686 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -28.556 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -81.248 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | -4.168.683 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -34.737 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -23.796 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -67.704 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | -3.473.763 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 890 | 17.638 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 610 | 12.082 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 1.736 | 34.378 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 89.069 | 1.763.894 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 16.748 | 16.748 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 11.472 | 11.472 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 32.642 | 32.642 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 1.674.825 | 1.674.825 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | -14.968.722 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | 14,0000 | 320.000 | 4.480 | 1.866.126 | ||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | 1.546.126 | 1.546.126 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Series E Preferred Stock | I | -2.234.137 | 0 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Series E Preferred Stock | I | -2.234.137 | 0 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | 14,0000 | 25.000 | 350 | 255.764 | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | 14,0000 | 25.000 | 350 | 255.764 | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | 230.764 | 230.764 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | 230.764 | 230.764 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series E Preferred Stock | D | -6.581 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series D Preferred Stock | D | -11.182 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series C Preferred Stock | D | -90.110 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Common Stock | D | 13.414 | 13.414 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series E Preferred Stock | D | -887.073 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series D Preferred Stock | D | -1.506.901 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series C Preferred Stock | D | -12.143.933 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Common Stock | D | 1.807.820 | 1.807.820 | ||||||
| 2015-05-08 | 2015-05-06 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 14,00 | 163.437 | 163.437 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ramsdell Fred | LIFE | Stock Option (right to buy) | D | 14,00 | 17.600 | 17.600 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chrzanowski Holly D. | LIFE | Stock Option (right to buy) | D | 14,00 | 11.943 | 11.943 | |||||
| 2015-05-08 | 2015-05-06 | 4 | McKew John C. | LIFE | Stock Option (right to buy) | D | 14,00 | 25.144 | 25.144 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Kelly | LIFE | Stock Option (right to buy) | D | 14,00 | 34.573 | 34.573 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | 14,00 | 4.085 | 4.085 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chereau Frederic | LIFE | Stock Option (right to buy) | D | 14,00 | 22.001 | 22.001 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Graham Marcy | LIFE | Stock Option (right to buy) | D | 14,00 | 10.686 | 10.686 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Krueger Nancy | LIFE | Stock Option (right to buy) | D | 14,00 | 8.800 | 8.800 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ashlock Melissa A. | LIFE | Stock Option (right to buy) | D | 14,00 | 25.144 | 25.144 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Weiner David M. | LIFE | Stock Option (right to buy) | D | 14,00 | 44.002 | 44.002 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Cubitt Andrew | LIFE | Stock Option (right to buy) | D | 14,00 | 5.657 | 5.657 | |||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | 136.328 | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | 136.328 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | 269.419 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | 148.853 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | 269.419 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | 148.853 | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | 25.144 | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | 443.832 | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | 443.832 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18.858 | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | 3.770 | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | 3.770 | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | 558 | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | 558 | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | 25.734 | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | 25.734 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 189.951 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 189.951 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | 98.199 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | 98.199 | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | 10.056 | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | 10.056 |
