| Deler fremragende | 52,835,203 shares |
| Insideraktier | 1.608.359 shares |
| Insider ejerskab | 3,04 % |
| Total Insiders | 36 |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Insiderhandelsdiagram
Iterum Therapeutics plc insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Brenton Karl Ahrens Director - [D] | 0 | 0 | |
|
Canaan X L.p.
Director, 10% Owner -
[D]
|
1.733.170 | 115.545 | |
|
Canaan Partners X LLC
Director, 10% Owner -
[D]
|
0 | 115.545 | |
| Mark Chin Director - [D] | 18.306 | 18.306 | |
|
Alexander J Denner
10% Owner -
|
0 | 0 | |
| Dunne Michael W. Director - [D] | 241.001 | 241.001 | |
| Paul R Edick Director - [D] | 31.390 | 2.093 | |
|
Fhm Vii, L.l.c.
10% Owner -
|
333.000 | 22.744 | |
|
Fhm Vii, L.p.
10% Owner -
|
333.000 | 22.744 | |
| Fishman Corey N. Chief Executive Officer, Director - [D] [O] | 137.062 | 137.062 | |
|
Frazier Healthcare VII, L.P.
10% Owner -
|
333.000 | 22.744 | |
|
Frazier Healthcare VII-A, L.P.
10% Owner -
|
333.000 | 22.744 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
James Healy
10% Owner -
|
1.226.514 | 81.768 | |
| Ronald Hunt Director - [D] | 91.122 | 91.122 | |
| Beth Hecht Director - [D] | 18.839 | 18.839 | |
| Patrick J Heron Director - [D] | 9.006 | 600 | |
| David George Kelly Director - [D] | 37.108 | 2.474 | |
|
Peter Kolchinsky
10% Owner -
|
11.651.597 | 776.773 | |
|
Vijay K Lathi
10% Owner -
|
384.615 | 25.641 | |
| Shahzad Malik Director - [D] | 838.325 | 55.888 | |
| Matthews Judith M. Chief Financial Officer - [O] | 8.135 | 8.135 | |
|
Anand Mehra
10% Owner -
|
1.726.514 | 115.101 | |
|
Michael Powell
10% Owner -
|
1.226.514 | 81.768 | |
| Sailaja Puttagunta Chief Medical Officer - [O] | 10.369 | 10.369 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Ra Capital Management, Llc
10% Owner -
|
11.651.597 | 776.773 | |
|
RA Capital Healthcare Fund LP
10% Owner -
|
11.651.597 | 776.773 | |
|
Liam Ratcliffe
10% Owner -
|
384.615 | 25.641 | |
|
Sarissa Capital Catapult Fund LLC
10% Owner -
|
0 | 0 | |
|
Sarissa Capital Hawkeye Fund LP
10% Owner -
|
0 | 0 | |
|
Sarissa Capital Management LP
10% Owner -
|
0 | 0 | |
|
Sarissa Capital Master Fund II LP
10% Owner -
|
0 | 0 | |
|
Sarissa Capital Offshore Master Fund LP
10% Owner -
|
0 | 0 | |
| Schaffnit Jeffrey R. Chief Commercial Officer - [O] | 0 | 0 | |
|
Shah Rajeev M.
10% Owner -
|
11.651.597 | 776.773 | |
|
Sofinnova Management IX, L.L.C.
10% Owner -
|
1.226.514 | 81.768 | |
|
Sofinnova Venture Partners IX, L.P.
10% Owner -
|
1.226.514 | 81.768 |
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i ITRMF / Iterum Therapeutics plc. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i ITRMF / Iterum Therapeutics plc. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-11-20 | 2025-11-18 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 0,3652 | 6.000 | 2 | 241.001 | ||||
| 2025-08-12 | 2025-08-08 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 0,7236 | 15.000 | 11 | 235.001 | ||||
| 2024-08-12 | 2024-08-06 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 82.613 | 137.062 | ||||||
| 2024-08-12 | 2024-08-06 | 4 | HUNT RONALD By New Leaf Biopharma Opportunities II, L.P. | ITRM | Ordinary Shares | I | 65.481 | 91.122 | ||||||
| 2024-08-12 | 2024-08-06 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 182.453 | 253.898 | ||||||
| 2024-08-12 | 2024-08-06 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 106.247 | 220.001 | ||||||
| 2023-12-27 | 2023-12-22 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 1,4000 | 25.000 | 35 | 113.754 | ||||
| 2023-12-19 | 2023-12-18 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 1,8442 | 10.000 | 18 | 88.754 | ||||
| 2023-12-04 | 2023-12-01 | 4 | Puttagunta Sailaja | ITRM | Ordinary Shares | D | 2,1200 | -2.933 | -6 | 10.369 | ||||
| 2023-12-04 | 2023-12-01 | 4 | Puttagunta Sailaja | ITRM | Ordinary Shares | D | 8.333 | 13.302 | ||||||
| 2023-11-27 | 2023-11-22 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 2,0345 | 20.000 | 41 | 78.754 | ||||
| 2023-11-20 | 2023-11-20 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 1,5863 | 10.000 | 16 | 54.449 | ||||
| 2023-10-02 | 2023-10-01 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 5.479 | 14.346 | ||||||
| 2023-10-02 | 2023-10-01 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 3.487 | 58.754 | ||||||
| 2023-07-03 | 2023-07-01 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 2.796 | 8.867 | ||||||
| 2023-07-03 | 2023-07-01 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 1.779 | 55.267 | ||||||
| 2023-06-15 | 2023-06-15 | 4 | Hecht Beth | ITRM | Ordinary Shares | D | 15.853 | 18.839 | ||||||
| 2023-06-15 | 2023-06-15 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 15.853 | 53.488 | ||||||
| 2023-06-15 | 2023-06-15 | 4 | Chin Mark | ITRM | Ordinary Shares | D | 15.853 | 18.306 | ||||||
| 2023-06-05 | 2023-04-01 | 4/A | Dunne Michael W. | ITRM | Ordinary Shares | D | 1.299 | 37.635 | ||||||
| 2023-04-03 | 2023-04-01 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 1.299 | 37.636 | ||||||
| 2023-04-03 | 2023-04-01 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 2.041 | 6.071 | ||||||
| 2023-03-14 | 2023-03-11 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 0,9600 | -2.883 | -3 | 8.135 | ||||
| 2023-03-14 | 2023-03-11 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 6.666 | 11.018 | ||||||
| 2023-03-14 | 2023-03-11 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 0,9600 | -5.683 | -5 | 44.449 | ||||
| 2023-03-14 | 2023-03-11 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 14.333 | 50.132 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 1.197 | 4.030 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 761 | 36.337 | ||||||
| 2022-12-05 | 2022-12-02 | 4 | Puttagunta Sailaja | ITRM | Ordinary Shares | D | 1,3200 | -3.365 | -4 | 4.969 | ||||
| 2022-12-05 | 2022-12-01 | 4 | Puttagunta Sailaja | ITRM | Ordinary Shares | D | 8.334 | 8.334 | ||||||
| 2022-09-20 | 2022-09-20 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 1,7817 | -7.246 | -13 | 0 | ||||
| 2022-09-20 | 2022-09-19 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 1,7652 | -15.000 | -26 | 7.246 | ||||
| 2022-09-20 | 2022-09-16 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 1,9028 | -15.000 | -29 | 22.246 | ||||
| 2022-09-15 | 2022-09-15 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,0181 | -15.000 | -30 | 37.246 | ||||
| 2022-09-15 | 2022-09-14 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,0971 | -15.000 | -31 | 52.246 | ||||
| 2022-09-15 | 2022-09-13 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,1412 | -15.000 | -32 | 67.246 | ||||
| 2022-09-12 | 2022-09-12 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,3072 | -15.000 | -35 | 82.246 | ||||
| 2022-09-12 | 2022-09-09 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,3153 | -15.000 | -35 | 97.246 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | I | 2,2635 | -3.298 | -7 | 112.246 | ||||
| 2022-09-09 | 2022-09-07 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 2,2200 | 10.000 | 22 | 35.576 | ||||
| 2022-06-24 | 2022-06-23 | 4 | Hecht Beth | ITRM | Ordinary Shares | D | 36.798 | 44.805 | ||||||
| 2022-06-24 | 2022-06-23 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 36.798 | 383.647 | ||||||
| 2022-06-24 | 2022-06-23 | 4 | Chin Mark | ITRM | Ordinary Shares | D | 36.798 | 36.798 | ||||||
| 2022-06-24 | 2022-06-23 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 36.798 | 42.501 | ||||||
| 2022-03-29 | 2022-03-25 | 4 | Dunne Michael W. | ITRM | Restricted Share Units | D | 11.426 | 11.426 | ||||||
| 2022-03-29 | 2022-03-25 | 4 | Dunne Michael W. | ITRM | Restricted Share Units | D | -10.494 | 0 | ||||||
| 2022-03-29 | 2022-03-25 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 10.494 | 346.849 | ||||||
| 2022-03-29 | 2022-03-25 | 4 | Ahrens Brenton Karl | ITRM | Stock Option (Right to Buy) | D | 0,45 | 47.436 | 47.436 | |||||
| 2022-03-29 | 2022-03-25 | 4 | HUNT RONALD | ITRM | Restricted Share Units | D | 17.955 | 17.955 | ||||||
| 2022-03-22 | 2022-03-18 | 4 | Hecht Beth | ITRM | Restricted Share Units | D | -7.642 | 0 | ||||||
| 2022-03-22 | 2022-03-18 | 4 | Hecht Beth | ITRM | Ordinary Shares | D | 7.642 | 8.007 | ||||||
| 2022-03-15 | 2022-03-14 | 4/A | Matthews Judith M. | ITRM | Ordinary Shares | D | 0,3100 | -63.340 | -20 | 65.292 | ||||
| 2022-03-15 | 2022-03-14 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 0,3800 | -47.132 | -18 | 81.500 | ||||
| 2022-03-15 | 2022-03-11 | 4 | Matthews Judith M. | ITRM | Restricted Share Units | D | -100.000 | 100.000 | ||||||
| 2022-03-15 | 2022-03-11 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 100.000 | 128.632 | ||||||
| 2022-03-15 | 2022-03-11 | 4 | Fishman Corey N. | ITRM | Restricted Share Units | D | -215.000 | 215.000 | ||||||
| 2022-03-15 | 2022-03-11 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 215.000 | 537.008 | ||||||
| 2021-12-14 | 2021-12-10 | 4 | Puttagunta Sailaja | ITRM | Restricted Share Units | D | 500.000 | 500.000 | ||||||
| 2021-12-14 | 2021-12-10 | 4 | Puttagunta Sailaja | ITRM | Share Option (Right to Buy) | D | 0,48 | 1.800.000 | 1.800.000 | |||||
| 2021-07-27 | 2021-07-25 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 80.000 | 336.355 | ||||||
| 2021-06-25 | 2021-06-23 | 4 | Kelly David George | ITRM | Stock Option (Right to Buy) | D | 2,01 | 64.706 | 64.706 | |||||
| 2021-06-25 | 2021-06-23 | 4 | Chin Mark | ITRM | Restricted Stock Units | D | 36.798 | 36.798 | ||||||
| 2021-06-25 | 2021-06-23 | 4 | Matthews Judith M. | ITRM | Stock Option (Right to Buy) | D | 2,01 | 1.936.000 | 1.936.000 | |||||
| 2021-06-25 | 2021-06-23 | 4 | Hecht Beth | ITRM | Restricted Stock Units | D | 36.798 | 36.798 | ||||||
| 2021-06-25 | 2021-06-23 | 4 | HUNT RONALD | ITRM | Restricted Stock Units | D | 36.798 | 36.798 | ||||||
| 2021-06-25 | 2021-06-23 | 4 | Dunne Michael W. | ITRM | Restricted Stock Units | D | 36.798 | 36.798 | ||||||
| 2021-06-25 | 2021-06-23 | 4 | Ahrens Brenton Karl | ITRM | Stock Option (Right to Buy) | D | 2,01 | 64.706 | 64.706 | |||||
| 2021-06-25 | 2021-06-23 | 4 | Fishman Corey N. | ITRM | Stock Option (Right to Buy) | D | 2,01 | 5.280.000 | 5.280.000 | |||||
| 2021-04-21 | 3 | Hecht Beth | ITRM | Ordinary Shares | D | 365 | ||||||||
| 2021-03-29 | 2021-03-25 | 4 | Dunne Michael W. | ITRM | Restricted Stock Units | D | 10.494 | 10.494 | ||||||
| 2021-03-19 | 2021-03-18 | 4 | Hecht Beth | ITRM | Restricted Stock Units | D | 7.642 | 7.642 | ||||||
| 2021-03-15 | 2021-03-11 | 4 | Fishman Corey N. | ITRM | Restricted Share Units | D | 430.000 | 430.000 | ||||||
| 2021-03-15 | 2021-03-11 | 4 | Matthews Judith M. | ITRM | Restricted Share Units | D | 200.000 | 200.000 | ||||||
| 2021-03-03 | 2020-07-28 | 4 | Chin Mark | ITRM | Ordinary Shares | D | -11.857 | 0 | ||||||
| 2021-02-12 | 2021-02-12 | 4 | DENNER ALEXANDER J See footnotes | ITRM | Ordinary Shares | I | 2,2700 | -10.619.949 | -24.107 | 0 | ||||
| 2021-02-12 | 2021-02-11 | 4 | DENNER ALEXANDER J See Footnotes | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | -15.000.000 | 0 | ||||||
| 2021-02-12 | 2021-02-11 | 4 | DENNER ALEXANDER J See footnotes | ITRM | Ordinary Shares | I | 2,5900 | -10.000.000 | -25.900 | 10.619.949 | ||||
| 2021-02-12 | 2021-02-11 | 4 | DENNER ALEXANDER J See footnotes | ITRM | Ordinary Shares | I | 20.619.949 | 20.616.949 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | -8.486.000 | 0 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | ITRM | Ordinary Shares | I | 11.651.597 | 11.651.597 | ||||||
| 2021-01-27 | 2021-01-26 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 1,7300 | -85.445 | -148 | 322.008 | ||||
| 2021-01-27 | 2021-01-25 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 167.500 | 407.453 | ||||||
| 2021-01-27 | 2021-01-26 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 1,7300 | -33.868 | -59 | 28.632 | ||||
| 2021-01-27 | 2021-01-25 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 62.500 | 62.500 | ||||||
| 2021-01-27 | 2021-01-26 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 1,7300 | -33.143 | -57 | 256.355 | ||||
| 2021-01-27 | 2021-01-25 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 80.000 | 289.498 | ||||||
| 2020-10-28 | 2020-10-27 | 4 | Dunne Michael W. | ITRM | Warrants (right to buy) | D | 0,65 | 46.155 | 46.155 | |||||
| 2020-10-28 | 2020-10-27 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 61.540 | 209.498 | ||||||
| 2020-10-02 | 2020-09-30 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 1,6400 | -56.130 | -92 | 0 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Heron Patrick J | ITRM | Restricted Stock Units | D | -2.852 | 0 | ||||||
| 2020-07-06 | 2020-07-01 | 4 | Heron Patrick J | ITRM | Ordinary Shares | D | 2.852 | 9.006 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | HUNT RONALD | ITRM | Restricted Stock Units | D | -5.703 | 0 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | HUNT RONALD | ITRM | Ordinary Shares | D | 5.703 | 5.703 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | Chin Mark | ITRM | Restricted Stock Units | D | -5.703 | 0 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | Chin Mark | ITRM | Ordinary Shares | D | 5.703 | 11.857 | ||||||
| 2020-06-16 | 2020-06-13 | 4 | Kelly David George | ITRM | Restricted Stock Units | D | -11.406 | 0 | ||||||
| 2020-06-16 | 2020-06-13 | 4 | Kelly David George | ITRM | Ordinary Shares | D | 11.406 | 37.108 | ||||||
| 2020-06-12 | 2020-06-10 | 4 | Kelly David George | ITRM | Stock Option (Right to Buy) | D | 1,68 | 62.840 | 62.840 | |||||
| 2020-06-03 | 2020-06-02 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 1,6074 | -400.000 | -643 | 1.226.514 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 1,6912 | -100.000 | -169 | 1.626.514 | ||||
| 2020-04-09 | 2020-04-07 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 0 | |||||||
| 2020-04-09 | 2020-04-07 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Ordinary Shares | I | -1.089.903 | 0 | ||||||
| 2020-01-23 | 2020-01-21 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | D | 1.750.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | CANAAN X L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | D | 2.000.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Frazier Healthcare VII, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | D | 333.000,0000 | 333.000 | 110.889.000 | 333.000 | ||||
| 2020-01-23 | 2020-01-21 | 4 | Frazier Healthcare VII, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | D | 1.167.000,0000 | 1.167.000 | 1.361.889.000 | 1.167.000 | ||||
| 2020-01-23 | 2020-01-21 | 4 | Malik Shahzad By Advent Life Science Fund II LP. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 1.495.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 53.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | HUNT RONALD By New Leaf Biopharma Opportunities II, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 792.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 2.208.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 1.750.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Ahrens Brenton Karl By Canaan X L.P | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 2.000.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 1.900.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 333.000,0000 | |||||||
| 2020-01-23 | 2020-01-21 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | 6.500% Exchangeable Senior Subordinated Note due 2025 | I | 1.167.000,0000 | |||||||
| 2019-06-17 | 2019-06-13 | 4 | HEALY JAMES | ITRM | Restricted Stock Units | D | -5.703 | 5.703 | ||||||
| 2019-06-17 | 2019-06-13 | 4 | Chin Mark | ITRM | Restricted Stock Units | D | 5.703 | 5.703 | ||||||
| 2019-06-17 | 2019-06-13 | 4 | Heron Patrick J | ITRM | Restricted Stock Units | D | 2.852 | 2.852 | ||||||
| 2019-06-17 | 2019-06-13 | 4 | Heron Patrick J | ITRM | Stock Option (Right to Buy) | D | 6,74 | 9.836 | 9.836 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Malik Shahzad | ITRM | Stock Option (Right to Buy) | D | 6,74 | 19.671 | 19.671 | |||||
| 2019-06-17 | 2019-06-13 | 4 | HUNT RONALD | ITRM | Restricted Stock Units | D | 5.703 | 5.703 | ||||||
| 2019-06-17 | 2019-06-13 | 4 | Ahrens Brenton Karl | ITRM | Stock Option (Right to Buy) | D | 6,74 | 19.671 | 19.671 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Kelly David George | ITRM | Restricted Stock Units | D | 11.406 | 11.406 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Kelly David George | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Kelly David George | ITRM | Ordinary Shares | D | 6.154 | 25.702 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Ahrens Brenton Karl | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Ahrens Brenton Karl | ITRM | Ordinary Shares | D | 6.154 | 6.154 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Heron Patrick J | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Heron Patrick J | ITRM | Ordinary Shares | D | 6.154 | 6.154 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Chin Mark | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Chin Mark | ITRM | Ordinary Shares | D | 6.154 | 6.154 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | HEALY JAMES | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | HEALY JAMES | ITRM | Ordinary Shares | D | 6.154 | 6.154 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Edick Paul R | ITRM | Restricted Stock Units | D | -6.154 | 0 | ||||||
| 2019-05-29 | 2019-05-24 | 4 | Edick Paul R | ITRM | Ordinary Shares | D | 6.154 | 31.390 | ||||||
| 2019-02-19 | 2019-02-15 | 4 | Dunne Michael W. | ITRM | Stock Option (Right to Buy) | D | 5,80 | 85.000 | 85.000 | |||||
| 2019-02-19 | 2019-02-15 | 4 | Fishman Corey N. | ITRM | Stock Option (Right to Buy) | D | 5,80 | 150.000 | 150.000 | |||||
| 2019-02-19 | 2019-02-15 | 4 | Matthews Judith M. | ITRM | Stock Option (Right to Buy) | D | 5,80 | 30.000 | 30.000 | |||||
| 2018-12-04 | 2018-11-30 | 4 | Kelly David George | ITRM | Ordinary Shares | D | 6,2887 | 10.000 | 63 | 19.548 | ||||
| 2018-11-01 | 2018-10-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Ordinary Shares | I | 6,1000 | 58.000 | 354 | 1.089.903 | ||||
| 2018-09-06 | 2018-09-04 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 10,0000 | 500 | 5 | 147.958 | ||||
| 2018-08-28 | 2018-08-27 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 10,0000 | 500 | 5 | 147.458 | ||||
| 2018-08-28 | 2018-08-24 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 10,0000 | 500 | 5 | 146.958 | ||||
| 2018-08-27 | 2018-08-23 | 4 | Edick Paul R | ITRM | Ordinary Shares | D | 10,4374 | 500 | 5 | 25.236 | ||||
| 2018-08-21 | 2018-08-17 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 8,7328 | 2.000 | 17 | 239.953 | ||||
| 2018-06-01 | 2018-05-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Series B-2 Preferred Shares | I | -248.721 | 0 | ||||||
| 2018-06-01 | 2018-05-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Series B-1 Preferred Shares | I | -445.576 | 0 | ||||||
| 2018-06-01 | 2018-05-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Ordinary Shares | I | 13,0000 | 337.606 | 4.389 | 1.031.903 | ||||
| 2018-06-01 | 2018-05-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Ordinary Shares | I | 248.721 | 694.297 | ||||||
| 2018-06-01 | 2018-05-30 | 4 | Chin Mark By Arix Bioscience Holdings Ltd. | ITRM | Ordinary Shares | I | 445.576 | 445.576 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Series B-2 Preferred Shares | I | -148.603 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Series B-1 Preferred Shares | I | -178.230 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Series A Preferred Shares | I | -466.793 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Biopharma Opportunities II, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 384.615 | 5.000 | 384.615 | ||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 278.062 | 3.615 | 1.071.688 | ||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 148.603 | 793.626 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 178.230 | 645.023 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | HUNT RONALD By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 466.793 | 466.793 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Series B-2 Preferred Shares | I | -148.603 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Series B-1 Preferred Shares | I | -178.230 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Series A Preferred Shares | I | -466.793 | 0 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Biopharma Opportunities II, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 384.615 | 5.000 | 384.615 | ||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 278.062 | 3.615 | 1.071.688 | ||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 148.603 | 793.626 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 178.230 | 645.023 | ||||||
| 2018-05-31 | 2018-05-30 | 4 | Lathi Vijay K By New Leaf Ventures III, L.P. | ITRM | Ordinary Shares | I | 466.793 | 466.793 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Series B-2 Preferred Shares | D | -229.660 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Series B-1 Preferred Shares | D | -275.446 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Series A Preferred Shares | D | -721.408 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 13,0000 | 500.000 | 6.500 | 1.726.514 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 229.660 | 1.226.514 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 275.446 | 996.854 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | D | 721.408 | 721.408 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Series B-2 Preferred Shares | D | -1.591 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Series B-1 Preferred Shares | D | -4.050 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Series A Preferred Shares | D | -33.259 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 13,0000 | 3.000 | 39 | 237.953 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 1.591 | 234.953 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 4.050 | 233.362 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Fishman Corey N. | ITRM | Ordinary Shares | D | 33.259 | 229.312 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Series B-2 Preferred Shares | D | -2.917 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Series B-1 Preferred Shares | D | -4.050 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Series A Preferred Shares | D | -12.730 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 13,0000 | 2.000 | 26 | 146.458 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 2.917 | 144.458 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 4.050 | 141.541 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Dunne Michael W. | ITRM | Ordinary Shares | D | 12.730 | 137.491 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Series B-2 Preferred Shares | D | -2.466 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Series B-1 Preferred Shares | D | -3.038 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Series A Preferred Shares | D | -10.980 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 13,0000 | 4.000 | 52 | 56.130 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 2.466 | 52.130 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 3.038 | 49.664 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Matthews Judith M. | ITRM | Ordinary Shares | D | 10.980 | 46.626 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Series B-2 Preferred Shares | I | -44.940 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Series B-1 Preferred Shares | I | -53.899 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Series A Preferred Shares | I | -141.166 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Series B-2 Preferred Shares | I | -157.701 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Series B-1 Preferred Shares | I | -189.141 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Series A Preferred Shares | I | -495.370 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 101.150 | 1.315 | 341.155 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Ordinary Shares | I | 44.940 | 240.005 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Ordinary Shares | I | 53.899 | 195.065 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII-A, L.P. | ITRM | Ordinary Shares | I | 141.166 | 141.166 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 354.949 | 4.614 | 1.197.161 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Ordinary Shares | I | 157.701 | 842.212 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Ordinary Shares | I | 189.141 | 684.511 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Heron Patrick J By Frazier Healthcare VII, L.P. | ITRM | Ordinary Shares | I | 495.370 | 495.370 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Kelly David George | ITRM | Series A Preferred Shares | D | -9.548 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Kelly David George | ITRM | Ordinary Shares | D | 9.548 | 9.548 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Series B-2 Preferred Shares | D | -1.591 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Series B-1 Preferred Shares | D | -4.050 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Series A Preferred Shares | D | -15.913 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Ordinary Shares | D | 1.591 | 24.736 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Ordinary Shares | D | 4.050 | 23.145 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Edick Paul R | ITRM | Ordinary Shares | D | 15.913 | 19.095 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Series B-2 Preferred Shares | D | -229.660 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Series B-1 Preferred Shares | D | -275.446 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Series A Preferred Shares | D | -721.408 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Ordinary Shares | D | 13,0000 | 506.656 | 6.587 | 1.733.170 | ||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Ordinary Shares | D | 229.660 | 1.226.514 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Ordinary Shares | D | 275.446 | 996.854 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | CANAAN X L.P. | ITRM | Ordinary Shares | D | 721.408 | 721.408 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Series B-2 Preferred Shares | I | -229.660 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Series B-1 Preferred Shares | I | -275.446 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Series A Preferred Shares | I | -721.408 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 506.656 | 6.587 | 1.733.170 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Ordinary Shares | I | 229.660 | 1.226.514 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Ordinary Shares | I | 275.446 | 996.854 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Ahrens Brenton Karl By Canaan X, L.P. | ITRM | Ordinary Shares | I | 721.408 | 721.408 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences Fund II LP | ITRM | Series B-2 Preferred Shares | I | -218.338 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences Fund II LP | ITRM | Series B-1 Preferred Shares | I | -391.147 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | Series B-2 Preferred Shares | I | -7.771 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | Series B-1 Preferred Shares | I | -13.921 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences Fund II LP | ITRM | Ordinary Shares | I | 13,0000 | 228.840 | 2.975 | 838.325 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences Fund II LP | ITRM | Ordinary Shares | I | 218.338 | 609.485 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences Fund II LP | ITRM | Ordinary Shares | I | 391.147 | 391.147 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | Ordinary Shares | I | 13,0000 | 8.144 | 106 | 29.836 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | Ordinary Shares | I | 7.771 | 21.692 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | Malik Shahzad By Advent Life Sciences LLP | ITRM | Ordinary Shares | I | 13.921 | 13.921 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Series B-2 Preferred Shares | I | -229.660 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Series B-1 Preferred Shares | I | -275.446 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Series A Preferred Shares | I | -721.408 | 0 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | I | 13,0000 | 500.000 | 6.500 | 1.726.514 | ||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | I | 229.660 | 1.226.514 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | I | 275.446 | 996.854 | ||||||
| 2018-05-30 | 2018-05-30 | 4 | HEALY JAMES By Sofinnova Venture Partners IX, L.P. | ITRM | Ordinary Shares | I | 721.408 | 721.408 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | Chin Mark | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | Edick Paul R | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | Schaffnit Jeffrey R. | ITRM | Stock Option (Right to Buy) | D | 13,00 | 6.365 | 6.365 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Schaffnit Jeffrey R. | ITRM | Stock Option (Right to Buy) | D | 13,00 | 25.461 | 25.461 | |||||
| 2018-05-29 | 2018-05-24 | 4 | HUNT RONALD | ITRM | Stock Option (Right to Buy) | D | 13,00 | 11.241 | 11.241 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Matthews Judith M. | ITRM | Stock Option (Right to Buy) | D | 13,00 | 23.870 | 23.870 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Fishman Corey N. | ITRM | Stock Option (Right to Buy) | D | 13,00 | 127.307 | 127.307 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Ahrens Brenton Karl | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | HEALY JAMES | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | Dunne Michael W. | ITRM | Stock Option (Right to Buy) | D | 13,00 | 79.567 | 79.567 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Malik Shahzad | ITRM | Stock Option (Right to Buy) | D | 13,00 | 11.241 | 11.241 | |||||
| 2018-05-29 | 2018-05-24 | 4 | Kelly David George | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-29 | 2018-05-24 | 4 | Heron Patrick J | ITRM | Restricted Stock Units | D | 6.154 | 6.154 | ||||||
| 2018-05-24 | 3 | Fishman Corey N. | ITRM | Ordinary Shares | D | 392.106 | ||||||||
| 2018-05-24 | 3 | Fishman Corey N. | ITRM | Ordinary Shares | D | 392.106 | ||||||||
| 2018-05-24 | 3 | Fishman Corey N. | ITRM | Ordinary Shares | D | 392.106 | ||||||||
| 2018-05-24 | 3 | Dunne Michael W. | ITRM | Ordinary Shares | D | 249.522 | ||||||||
| 2018-05-24 | 3 | Dunne Michael W. | ITRM | Ordinary Shares | D | 249.522 | ||||||||
| 2018-05-24 | 3 | Dunne Michael W. | ITRM | Ordinary Shares | D | 249.522 | ||||||||
| 2018-05-24 | 3 | Matthews Judith M. | ITRM | Ordinary Shares | D | 71.292 | ||||||||
| 2018-05-24 | 3 | Matthews Judith M. | ITRM | Ordinary Shares | D | 71.292 | ||||||||
| 2018-05-24 | 3 | Matthews Judith M. | ITRM | Ordinary Shares | D | 71.292 | ||||||||
| 2018-05-24 | 3 | Schaffnit Jeffrey R. | ITRM | No securities are beneficially owned. | D | 0 | ||||||||
| 2018-05-24 | 3 | Edick Paul R | ITRM | Ordinary Shares | D | 6.364 | ||||||||
| 2018-05-24 | 3 | Edick Paul R | ITRM | Ordinary Shares | D | 6.364 | ||||||||
| 2018-05-24 | 3 | Edick Paul R | ITRM | Ordinary Shares | D | 6.364 |
