| Insideraktier | 23.873.734 shares |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Netto antal insidere, der køber (rang)
Netto antal insidere, der køber, er det samlede antal insiders, der køber minus det samlede antal insiders, der har solgt inden for de sidste 90 dage. Percentilrangen vises her (spænder fra 0 til 100%).
Procent af float købt af insidere (rangering)
Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.
Insiderhandelsdiagram
iTeos Therapeutics, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i ITOS / iTeos Therapeutics, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i ITOS / iTeos Therapeutics, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-08-29 | 2025-08-29 | 4 | Call Matthew | ITOS | Common Stock | D | -161.898 | 0 | ||||||
| 2025-08-29 | 2025-08-29 | 4 | McGrath Yvonne | ITOS | Common Stock | D | -46.300 | 0 | ||||||
| 2025-08-29 | 2025-08-29 | 4 | Gall Matthew | ITOS | Common Stock | D | -89.429 | 0 | ||||||
| 2025-08-29 | 2025-08-29 | 4 | Feltquate David | ITOS | Common Stock | D | -47.000 | 0 | ||||||
| 2025-08-29 | 2025-08-29 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | -94.027 | 0 | ||||||
| 2025-08-29 | 2025-08-29 | 4 | Detheux Michel | ITOS | Common Stock | D | -153.903 | 0 | ||||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 94.027 | 404 | 94.027 | ||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 18.000 | 77 | 153.903 | ||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 10,0200 | -43.883 | -440 | 0 | ||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 43.883 | 189 | 43.883 | ||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel | ITOS | Common Stock | D | 10,0200 | -8.400 | -84 | 135.903 | ||||
| 2025-06-11 | 2025-06-10 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 8.400 | 36 | 144.303 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 10,0300 | -43.882 | -440 | 0 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 43.882 | 189 | 43.882 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Detheux Michel | ITOS | Common Stock | D | 10,0300 | -8.400 | -84 | 135.903 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 8.400 | 36 | 144.303 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 10,2100 | -43.882 | -448 | 0 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 43.882 | 189 | 43.882 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Detheux Michel | ITOS | Common Stock | D | 10,2100 | -8.400 | -86 | 135.903 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 8.400 | 36 | 144.303 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 10,1500 | -43.882 | -445 | 0 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 43.882 | 189 | 43.882 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Detheux Michel | ITOS | Common Stock | D | 10,1500 | -8.400 | -85 | 135.903 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 8.400 | 36 | 144.303 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 10,1000 | -43.883 | -443 | 0 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Detheux Michel By MG3A | ITOS | Common Stock | I | 4,3000 | 43.883 | 189 | 43.883 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Detheux Michel | ITOS | Common Stock | D | 10,1000 | -8.400 | -85 | 135.903 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 8.400 | 36 | 144.303 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Hallal David | ITOS | Common Stock | D | 10,2400 | -38.228 | -391 | 0 | ||||
| 2025-06-06 | 2025-06-06 | 4 | Hallal David | ITOS | Common Stock | D | 4,3000 | 38.228 | 164 | 38.228 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Hallal David | ITOS | Common Stock | D | 10,1500 | -38.227 | -388 | 0 | ||||
| 2025-06-06 | 2025-06-05 | 4 | Hallal David | ITOS | Common Stock | D | 4,3000 | 38.227 | 164 | 38.227 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Hallal David | ITOS | Common Stock | D | 10,0700 | -38.227 | -385 | 0 | ||||
| 2025-06-06 | 2025-06-04 | 4 | Hallal David | ITOS | Common Stock | D | 4,3000 | 38.227 | 164 | 38.227 | ||||
| 2025-05-16 | 2025-05-15 | 4 | EcoR1 Capital, LLC See Note | ITOS | Common Stock | I | 8,0000 | 3.300.000 | 26.400 | 10.688.978 | ||||
| 2025-05-16 | 2025-05-14 | 4 | EcoR1 Capital, LLC See Note | ITOS | Common Stock | I | 7,4055 | 1.658.978 | 12.286 | 7.388.978 | ||||
| 2025-05-15 | 2025-05-13 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 8,0600 | -1.031.931 | -8.317 | 3.452.797 | ||||
| 2025-05-15 | 2025-05-13 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 8,0600 | -630.191 | -5.079 | 2.108.594 | ||||
| 2025-05-15 | 2025-05-13 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 8,0600 | -630.191 | -5.079 | 2.108.594 | ||||
| 2025-05-14 | 2025-05-13 | 4 | Van Hauwermeiren Timothy | ITOS | Common Stock | D | 4,3000 | 22.346 | 96 | 22.346 | ||||
| 2025-05-13 | 3 | EcoR1 Capital, LLC See Note | ITOS | Common Stock | I | 5.730.000 | ||||||||
| 2025-03-11 | 2025-03-07 | 4 | Call Matthew | ITOS | Common Stock | D | 24.000 | 161.898 | ||||||
| 2025-03-11 | 2025-03-07 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 15.300 | 46.300 | ||||||
| 2025-03-11 | 2025-03-07 | 4 | Gall Matthew | ITOS | Common Stock | D | 24.000 | 89.429 | ||||||
| 2025-03-11 | 2025-03-07 | 4 | Detheux Michel | ITOS | Common Stock | D | 77.000 | 135.903 | ||||||
| 2024-12-06 | 2024-12-06 | 4 | Feltquate David | ITOS | Common Stock | D | 47.000 | 47.000 | ||||||
| 2024-11-19 | 2024-11-19 | 4 | Gall Matthew | ITOS | Common Stock | D | 7,7270 | 5.000 | 39 | 65.429 | ||||
| 2024-05-14 | 2024-05-10 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 17,5000 | 1.142.857 | 20.000 | 2.946.915 | ||||
| 2024-05-14 | 2024-05-12 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | ITOS | Common Stock | I | -900.000 | 2.545.510 | ||||||
| 2023-12-07 | 2023-12-05 | 4 | Call Matthew | ITOS | Common Stock | D | 44.000 | 137.898 | ||||||
| 2023-12-07 | 2023-12-05 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 31.000 | 31.000 | ||||||
| 2023-12-07 | 2023-12-05 | 4 | Gall Matthew | ITOS | Common Stock | D | 41.000 | 60.429 | ||||||
| 2023-12-07 | 2023-12-05 | 4 | Detheux Michel | ITOS | Common Stock | D | 30.000 | 58.903 | ||||||
| 2023-10-12 | 2023-10-12 | 4 | Gall Matthew | ITOS | Common Stock | D | 8,3700 | 5.000 | 42 | 19.429 | ||||
| 2023-08-25 | 2023-08-23 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 16,8700 | -219.638 | -3.705 | 1.804.058 | ||||
| 2023-08-25 | 2023-08-23 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 15,6300 | -95.516 | -1.493 | 2.023.696 | ||||
| 2023-08-25 | 2023-08-23 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 14,1900 | -34.846 | -494 | 2.119.212 | ||||
| 2023-03-29 | 2023-03-28 | 4 | Call Matthew | ITOS | Common Stock | D | 2,9500 | 40.226 | 119 | 93.898 | ||||
| 2022-06-10 | 2022-06-09 | 4 | Hallal David | ITOS | Common Stock | D | 19,5100 | -1.171 | -23 | 0 | ||||
| 2022-06-10 | 2022-06-09 | 4 | Hallal David | ITOS | Common Stock | D | 4,2300 | 1.171 | 5 | 1.171 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 19,8600 | -10.577 | -210 | 0 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 4,2300 | 10.577 | 45 | 10.577 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 20,3900 | -11.899 | -243 | 0 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 2,9500 | 11.899 | 35 | 11.899 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 20,3900 | -5.968 | -122 | 0 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Hallal David | ITOS | Common Stock | D | 4,2300 | 5.968 | 25 | 5.968 | ||||
| 2022-05-11 | 2022-05-11 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 18,2487 | -337.109 | -6.152 | 2.154.058 | ||||
| 2022-05-11 | 2022-05-11 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 17,5320 | -891 | -16 | 2.491.167 | ||||
| 2022-05-11 | 2022-05-10 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 24,7653 | -4.850 | -120 | 2.492.058 | ||||
| 2022-05-11 | 2022-05-10 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 25,1798 | -95.150 | -2.396 | 2.496.908 | ||||
| 2022-05-11 | 2022-05-09 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 23,4656 | -200.000 | -4.693 | 2.592.058 | ||||
| 2022-05-11 | 2022-05-09 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 22,9089 | -25.000 | -573 | 2.792.058 | ||||
| 2022-05-02 | 2022-05-02 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 27,5332 | -92.700 | -2.552 | 2.817.058 | ||||
| 2022-05-02 | 2022-05-02 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 26,9050 | -7.300 | -196 | 2.909.758 | ||||
| 2022-05-02 | 2022-04-29 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 27,0145 | -115.000 | -3.107 | 2.917.058 | ||||
| 2022-05-02 | 2022-04-29 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 28,2154 | -10.000 | -282 | 3.032.058 | ||||
| 2022-05-02 | 2022-04-28 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 27,4021 | -150.000 | -4.110 | 3.042.058 | ||||
| 2022-04-19 | 2022-04-18 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,23 | -11.500 | 144.464 | |||||
| 2022-04-19 | 2022-04-18 | 4 | Detheux Michel | ITOS | Common Stock | D | 32,6400 | -33 | -1 | 26.263 | ||||
| 2022-04-19 | 2022-04-18 | 4 | Detheux Michel | ITOS | Common Stock | D | 31,8700 | -11.467 | -365 | 26.296 | ||||
| 2022-04-19 | 2022-04-18 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,2300 | 11.500 | 49 | 37.763 | ||||
| 2022-03-24 | 2022-03-23 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 32,8490 | 20.000 | 657 | 3.192.058 | ||||
| 2022-03-24 | 2022-03-22 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 33,4278 | 5.000 | 167 | 3.172.058 | ||||
| 2022-03-24 | 2022-03-22 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 33,0898 | 3.700 | 122 | 3.167.058 | ||||
| 2022-03-24 | 2022-03-22 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 31,8750 | 21.300 | 679 | 3.163.358 | ||||
| 2022-03-22 | 2022-03-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 36,5100 | -1.548 | -57 | 26.263 | ||||
| 2022-03-22 | 2022-03-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 35,2200 | -1.159 | -41 | 27.811 | ||||
| 2022-03-22 | 2022-03-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 34,1100 | -9.908 | -338 | 28.970 | ||||
| 2022-03-22 | 2022-03-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 33,4400 | -5.822 | -195 | 38.878 | ||||
| 2022-03-18 | 2022-03-17 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 35,2500 | -575.201 | -20.276 | 3.142.058 | ||||
| 2022-03-14 | 2022-03-11 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 4,30 | -3.500 | 178.938 | |||||
| 2022-03-14 | 2022-03-11 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 36,21 | 85.000 | 85.000 | |||||
| 2022-03-14 | 2022-03-11 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 36,0100 | -3.500 | -126 | 0 | ||||
| 2022-03-14 | 2022-03-11 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 3.500 | 15 | 3.500 | ||||
| 2022-03-14 | 2022-03-11 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 36,21 | 85.000 | 85.000 | |||||
| 2022-03-14 | 2022-03-11 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 36,21 | 352.500 | 352.500 | |||||
| 2022-03-14 | 2022-03-11 | 4 | Detheux Michel | ITOS | Common Stock | D | 10.000 | 44.700 | ||||||
| 2022-03-14 | 2022-03-11 | 4 | Gall Matthew | ITOS | Stock Option (Right to Buy) | D | 36,21 | 85.000 | 85.000 | |||||
| 2022-03-14 | 2022-03-11 | 4 | Call Matthew | ITOS | Option (right to buy) | D | 36,21 | 85.000 | 85.000 | |||||
| 2022-03-02 | 2022-03-01 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,24 | -10.000 | 85.123 | |||||
| 2022-03-02 | 2022-03-01 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 36,7570 | -10.000 | -368 | 0 | ||||
| 2022-03-02 | 2022-03-01 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2400 | 10.000 | 42 | 10.000 | ||||
| 2022-02-24 | 2022-02-23 | 4 | Detheux Michel | ITOS | Common Stock | D | 35,3200 | -544 | -19 | 34.700 | ||||
| 2022-02-24 | 2022-02-23 | 4 | Detheux Michel | ITOS | Common Stock | D | 34,3000 | -13.956 | -479 | 35.244 | ||||
| 2022-02-14 | 2022-02-11 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (right to buy) | D | 4,30 | -3.500 | 182.438 | |||||
| 2022-02-14 | 2022-02-11 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 36,2700 | -1.518 | -55 | 0 | ||||
| 2022-02-14 | 2022-02-11 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 35,5200 | -1.982 | -70 | 1.518 | ||||
| 2022-02-14 | 2022-02-11 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 3.500 | 15 | 3.500 | ||||
| 2022-01-26 | 2022-01-25 | 4 | Detheux Michel | ITOS | Common Stock | D | 36,2100 | -4.412 | -160 | 49.200 | ||||
| 2022-01-26 | 2022-01-25 | 4 | Detheux Michel | ITOS | Common Stock | D | 35,4500 | -10.088 | -358 | 53.612 | ||||
| 2022-01-18 | 2022-01-14 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 4,30 | -3.500 | 185.938 | |||||
| 2022-01-18 | 2022-01-14 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 39,5800 | -723 | -29 | 0 | ||||
| 2022-01-18 | 2022-01-14 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 39,2500 | -2.777 | -109 | 723 | ||||
| 2022-01-18 | 2022-01-14 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 3.500 | 15 | 3.500 | ||||
| 2022-01-06 | 2022-01-05 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 42,0300 | -18.135 | -762 | 2.738.785 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 46,4700 | -7.671 | -356 | 2.756.920 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 45,3200 | -6.768 | -307 | 2.764.591 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 43,2000 | -19.366 | -837 | 2.771.359 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 42,0500 | -94.745 | -3.984 | 2.790.725 | ||||
| 2022-01-06 | 2022-01-05 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 42,0300 | -18.135 | -762 | 2.738.785 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 46,4700 | -7.671 | -356 | 2.756.920 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 45,3200 | -6.768 | -307 | 2.764.591 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 43,2000 | -19.366 | -837 | 2.771.359 | ||||
| 2022-01-06 | 2022-01-04 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 42,0500 | -94.745 | -3.984 | 2.790.725 | ||||
| 2022-01-06 | 2022-01-05 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 42,0300 | -30.347 | -1.275 | 4.484.728 | ||||
| 2022-01-06 | 2022-01-04 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 46,4700 | -12.829 | -596 | 4.515.075 | ||||
| 2022-01-06 | 2022-01-04 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 45,3200 | -11.318 | -513 | 4.527.904 | ||||
| 2022-01-06 | 2022-01-04 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 43,2000 | -32.396 | -1.400 | 4.539.222 | ||||
| 2022-01-06 | 2022-01-04 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 42,0500 | -158.579 | -6.668 | 4.571.618 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 45,4777 | -2.517 | -114 | 0 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 44,4416 | -11.199 | -498 | 2.517 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 43,3596 | -3.138 | -136 | 13.716 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 41,8420 | -29.623 | -1.239 | 16.854 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 45,4777 | -7.483 | -340 | 3.717.259 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 44,4416 | -33.297 | -1.480 | 3.724.742 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 43,3600 | -9.366 | -406 | 3.758.039 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 41,8420 | -88.054 | -3.684 | 3.767.405 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 50,6338 | -731 | -37 | 46.477 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 49,3749 | -1.682 | -83 | 47.208 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 47,6275 | -23.353 | -1.112 | 48.890 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 50,6338 | -17.173 | -870 | 3.855.459 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 49,3745 | -39.481 | -1.949 | 3.872.632 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 47,6462 | -432.903 | -20.626 | 3.912.113 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 4,30 | -7.000 | 189.438 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 51,9000 | -7.000 | -363 | 0 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 7.000 | 30 | 7.000 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Biniszkiewicz Detlev | ITOS | Stock Option (Right to Buy) | D | 19,00 | -3.500 | 13.108 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Biniszkiewicz Detlev | ITOS | Common Stock | D | 51,9000 | -3.500 | -182 | 0 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Biniszkiewicz Detlev | ITOS | Common Stock | D | 19,0000 | 3.500 | 66 | 3.500 | ||||
| 2021-12-28 | 2021-12-27 | 4 | Gall Matthew | ITOS | Common Stock | D | 46,4500 | -5.000 | -232 | 14.429 | ||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,30 | -1.663 | 60.000 | |||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 45,3700 | -9.493 | -431 | 63.700 | ||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 44,6200 | -5.007 | -223 | 73.193 | ||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 44,9200 | -149 | -7 | 78.200 | ||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 44,3100 | -1.514 | -67 | 78.349 | ||||
| 2021-12-22 | 2021-12-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 1.663 | 7 | 79.863 | ||||
| 2021-12-22 | 2021-12-21 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,30 | -19.226 | 61.663 | |||||
| 2021-12-22 | 2021-12-21 | 4 | Detheux Michel | ITOS | Common Stock | D | 45,0600 | -5.580 | -251 | 78.200 | ||||
| 2021-12-22 | 2021-12-21 | 4 | Detheux Michel | ITOS | Common Stock | D | 44,1500 | -13.646 | -602 | 83.780 | ||||
| 2021-12-22 | 2021-12-21 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 19.226 | 83 | 97.426 | ||||
| 2021-12-22 | 2021-12-20 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,30 | -9.111 | 80.889 | |||||
| 2021-12-22 | 2021-12-20 | 4 | Detheux Michel | ITOS | Common Stock | D | 43,9400 | -9.111 | -400 | 78.200 | ||||
| 2021-12-22 | 2021-12-20 | 4 | Detheux Michel | ITOS | Common Stock | D | 4,3000 | 9.111 | 39 | 87.311 | ||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel By MG3A | ITOS | Stock Option (Right to Buy) | I | 41,58 | 106.200 | 106.200 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 41,58 | -106.200 | 37.800 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel By MG3A | ITOS | Stock Option (Right to Buy) | I | 19,00 | 776.600 | 776.600 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 19,00 | -776.600 | 258.824 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel By MG3A | ITOS | Stock Option (Right to Buy) | I | 6,15 | 52.700 | 52.700 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 6,15 | -52.700 | 17.544 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel By MG3A | ITOS | Stock Option (Right to Buy) | I | 4,23 | 185.000 | 185.000 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,23 | -185.000 | 155.964 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel By MG3A | ITOS | Stock Option (Right to Buy) | I | 4,30 | 313.442 | 313.442 | |||||
| 2021-12-22 | 2021-12-02 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 4,30 | -313.442 | 90.000 | |||||
| 2021-12-22 | 2021-12-20 | 4 | Hallal David | ITOS | Stock Option (Right to Buy) | D | 2,95 | -30.000 | 37.039 | |||||
| 2021-12-22 | 2021-12-20 | 4 | Hallal David | ITOS | Stock Option (Right to Buy) | D | 4,30 | -20.000 | 114.682 | |||||
| 2021-12-22 | 2021-12-20 | 4 | Hallal David | ITOS | Common Stock | D | 43,5700 | -50.000 | -2.178 | 0 | ||||
| 2021-12-22 | 2021-12-20 | 4 | Hallal David | ITOS | Common Stock | D | 2,9500 | 30.000 | 88 | 50.000 | ||||
| 2021-12-22 | 2021-12-20 | 4 | Hallal David | ITOS | Common Stock | D | 4,3000 | 20.000 | 86 | 20.000 | ||||
| 2021-12-17 | 2021-12-17 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (right to buy) | D | 4,30 | -7.000 | 196.438 | |||||
| 2021-12-17 | 2021-12-17 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 41,0000 | -7.000 | -287 | 0 | ||||
| 2021-12-17 | 2021-12-17 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 7.000 | 30 | 7.000 | ||||
| 2021-12-10 | 2021-12-10 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (right to buy) | D | 4,30 | -3.500 | 203.438 | |||||
| 2021-12-10 | 2021-12-10 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 34,5000 | -3.500 | -121 | 0 | ||||
| 2021-12-10 | 2021-12-10 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 3.500 | 15 | 3.500 | ||||
| 2021-12-07 | 2021-12-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,1100 | -1.494 | -51 | 2.885.470 | ||||
| 2021-12-07 | 2021-12-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 33,1500 | -17.962 | -595 | 2.886.964 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,0400 | -60 | -2 | 2.904.926 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,0800 | -508 | -17 | 2.904.986 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 33,5700 | -1.171 | -39 | 2.905.494 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 32,3500 | -8.469 | -274 | 2.906.665 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 36,2600 | -179 | -6 | 2.915.134 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,4400 | -2.419 | -86 | 2.915.313 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,6800 | -17.569 | -609 | 2.917.732 | ||||
| 2021-12-07 | 2021-12-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,1100 | -1.494 | -51 | 2.885.470 | ||||
| 2021-12-07 | 2021-12-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 33,1500 | -17.962 | -595 | 2.886.964 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,0400 | -60 | -2 | 2.904.926 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,0800 | -508 | -17 | 2.904.986 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 33,5700 | -1.171 | -39 | 2.905.494 | ||||
| 2021-12-07 | 2021-12-06 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 32,3500 | -8.469 | -274 | 2.906.665 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 36,2600 | -179 | -6 | 2.915.134 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,4400 | -2.419 | -86 | 2.915.313 | ||||
| 2021-12-07 | 2021-12-03 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,6800 | -17.569 | -609 | 2.917.732 | ||||
| 2021-12-07 | 2021-12-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,1100 | -2.499 | -85 | 4.730.197 | ||||
| 2021-12-07 | 2021-12-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 33,1500 | -30.059 | -996 | 4.732.696 | ||||
| 2021-12-07 | 2021-12-06 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,0400 | -100 | -4 | 4.762.755 | ||||
| 2021-12-07 | 2021-12-06 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,0800 | -850 | -29 | 4.762.855 | ||||
| 2021-12-07 | 2021-12-06 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 33,5700 | -1.960 | -66 | 4.763.705 | ||||
| 2021-12-07 | 2021-12-06 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 32,3500 | -14.173 | -458 | 4.765.665 | ||||
| 2021-12-07 | 2021-12-03 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 36,2600 | -300 | -11 | 4.779.838 | ||||
| 2021-12-07 | 2021-12-03 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,4400 | -4.047 | -143 | 4.780.138 | ||||
| 2021-12-07 | 2021-12-03 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,6800 | -29.402 | -1.020 | 4.784.185 | ||||
| 2021-12-02 | 2021-12-02 | 4 | MPM BIOVENTURES 2018, L.P. See Fpotnote | ITOS | Common Stock | I | 34,8300 | -7.430 | -259 | 2.935.301 | ||||
| 2021-12-02 | 2021-12-02 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 33,7400 | -29.757 | -1.004 | 2.942.731 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,3400 | -896 | -32 | 2.972.488 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,6100 | -5.457 | -189 | 2.973.384 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 33,8200 | -6.042 | -204 | 2.978.841 | ||||
| 2021-12-02 | 2021-11-30 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,1900 | -28.076 | -988 | 2.984.883 | ||||
| 2021-12-02 | 2021-11-30 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,6200 | -5.861 | -203 | 3.012.959 | ||||
| 2021-12-02 | 2021-12-02 | 4 | MPM BioVentures 2014, L.P. See Fpotnote | ITOS | Common Stock | I | 34,8300 | -7.430 | -259 | 2.935.301 | ||||
| 2021-12-02 | 2021-12-02 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 33,7400 | -29.757 | -1.004 | 2.942.731 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,3400 | -896 | -32 | 2.972.488 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,6100 | -5.457 | -189 | 2.973.384 | ||||
| 2021-12-02 | 2021-12-01 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 33,8200 | -6.042 | -204 | 2.978.841 | ||||
| 2021-12-02 | 2021-11-30 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,1900 | -28.076 | -988 | 2.984.883 | ||||
| 2021-12-02 | 2021-11-30 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,6200 | -5.861 | -203 | 3.012.959 | ||||
| 2021-12-02 | 2021-12-02 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,8300 | -12.434 | -433 | 4.813.587 | ||||
| 2021-12-02 | 2021-12-02 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 33,7400 | -49.796 | -1.680 | 4.826.021 | ||||
| 2021-12-02 | 2021-12-01 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,3400 | -1.500 | -53 | 4.875.817 | ||||
| 2021-12-02 | 2021-12-01 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,6100 | -9.131 | -316 | 4.877.317 | ||||
| 2021-12-02 | 2021-12-01 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 33,8200 | -10.111 | -342 | 4.886.448 | ||||
| 2021-12-02 | 2021-11-30 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,1900 | -46.992 | -1.654 | 4.896.559 | ||||
| 2021-12-02 | 2021-11-30 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,6200 | -9.809 | -340 | 4.943.551 | ||||
| 2021-11-30 | 2021-11-29 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,3700 | -298 | -11 | 3.018.820 | ||||
| 2021-11-30 | 2021-11-29 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 34,4600 | -10.073 | -347 | 3.019.118 | ||||
| 2021-11-30 | 2021-11-26 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 36,0300 | -6.129 | -221 | 3.029.191 | ||||
| 2021-11-30 | 2021-11-26 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,4900 | -6.545 | -232 | 3.035.320 | ||||
| 2021-11-30 | 2021-11-29 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,3700 | -298 | -11 | 3.018.820 | ||||
| 2021-11-30 | 2021-11-29 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 34,4600 | -10.073 | -347 | 3.019.118 | ||||
| 2021-11-30 | 2021-11-26 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 36,0300 | -6.129 | -221 | 3.029.191 | ||||
| 2021-11-30 | 2021-11-26 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,4900 | -6.545 | -232 | 3.035.320 | ||||
| 2021-11-30 | 2021-11-29 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,3700 | -500 | -18 | 4.953.360 | ||||
| 2021-11-30 | 2021-11-29 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 34,4600 | -16.856 | -581 | 4.953.860 | ||||
| 2021-11-30 | 2021-11-26 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 36,0300 | -10.258 | -370 | 4.970.716 | ||||
| 2021-11-30 | 2021-11-26 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,4900 | -10.952 | -389 | 4.980.974 | ||||
| 2021-11-24 | 2021-11-23 | 4 | Detheux Michel | ITOS | Common Stock | D | 36,0800 | -14.500 | -523 | 78.200 | ||||
| 2021-11-24 | 2021-11-22 | 4 | Detheux Michel | ITOS | Stock Option (right to buy) | D | 12,45 | -16.263 | 0 | |||||
| 2021-11-24 | 2021-11-22 | 4 | Detheux Michel | ITOS | Common Stock | D | 12,4500 | 16.263 | 202 | 92.700 | ||||
| 2021-11-24 | 2021-11-24 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 37,0200 | -21.965 | -813 | 4.991.926 | ||||
| 2021-11-24 | 2021-11-24 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 36,0500 | -30.696 | -1.107 | 5.013.891 | ||||
| 2021-11-24 | 2021-11-24 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 35,2000 | -8.147 | -287 | 5.044.587 | ||||
| 2021-11-24 | 2021-11-23 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 36,5000 | -600 | -22 | 5.052.734 | ||||
| 2021-11-24 | 2021-11-23 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 36,2100 | -32.876 | -1.190 | 5.053.334 | ||||
| 2021-11-24 | 2021-11-22 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 37,8100 | -19.758 | -747 | 5.086.210 | ||||
| 2021-11-24 | 2021-11-22 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 37,1600 | -15.575 | -579 | 5.105.986 | ||||
| 2021-11-24 | 2021-11-17 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | -15.671 | 5.121.543 | ||||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 37,0200 | -13.126 | -486 | 3.041.865 | ||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 36,0500 | -18.343 | -661 | 3.054.991 | ||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 35,2000 | -4.868 | -171 | 3.073.334 | ||||
| 2021-11-24 | 2021-11-23 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 36,5000 | -359 | -13 | 3.078.202 | ||||
| 2021-11-24 | 2021-11-23 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 36,2100 | -19.645 | -711 | 3.078.561 | ||||
| 2021-11-24 | 2021-11-22 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 37,8100 | -11.807 | -446 | 3.098.206 | ||||
| 2021-11-24 | 2021-11-22 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 37,1600 | -9.307 | -346 | 3.110.013 | ||||
| 2021-11-24 | 2021-11-17 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | -15.671 | 3.119.320 | ||||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 37,0200 | -13.126 | -486 | 3.041.865 | ||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 36,0500 | -18.343 | -661 | 3.054.991 | ||||
| 2021-11-24 | 2021-11-24 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 35,2000 | -4.868 | -171 | 3.073.334 | ||||
| 2021-11-24 | 2021-11-23 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 36,5000 | -359 | -13 | 3.078.202 | ||||
| 2021-11-24 | 2021-11-23 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 36,2100 | -19.645 | -711 | 3.078.561 | ||||
| 2021-11-24 | 2021-11-22 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 37,8100 | -11.807 | -446 | 3.098.206 | ||||
| 2021-11-24 | 2021-11-22 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 37,1600 | -9.307 | -346 | 3.110.013 | ||||
| 2021-11-24 | 2021-11-17 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | -15.671 | 3.119.320 | ||||||
| 2021-11-19 | 2021-11-18 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (right to buy) | D | 4,30 | -28.000 | 206.938 | |||||
| 2021-11-19 | 2021-11-18 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 34,5000 | -28.000 | -966 | 0 | ||||
| 2021-11-19 | 2021-11-18 | 4 | Lager Joanne Jenkins | ITOS | Common Stock | D | 4,3000 | 28.000 | 120 | 28.000 | ||||
| 2021-11-03 | 2021-11-03 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,8870 | -6.085 | -176 | 76.437 | ||||
| 2021-11-03 | 2021-11-02 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,4150 | -14.391 | -409 | 82.522 | ||||
| 2021-11-03 | 2021-11-01 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0000 | -81 | -2 | 96.913 | ||||
| 2021-10-25 | 2021-10-21 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0001 | -196 | -5 | 96.994 | ||||
| 2021-10-19 | 2021-10-19 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0000 | -201 | -6 | 97.190 | ||||
| 2021-10-19 | 2021-10-15 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0100 | -1.635 | -46 | 97.391 | ||||
| 2021-10-18 | 2021-10-18 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,1400 | -6.167 | -167 | 3.134.991 | ||||
| 2021-10-18 | 2021-10-15 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,0100 | -2.039 | -57 | 3.141.158 | ||||
| 2021-10-18 | 2021-10-15 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,5300 | -8.893 | -245 | 3.143.197 | ||||
| 2021-10-18 | 2021-10-18 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,1400 | -6.167 | -167 | 3.134.991 | ||||
| 2021-10-18 | 2021-10-15 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,0100 | -2.039 | -57 | 3.141.158 | ||||
| 2021-10-18 | 2021-10-15 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,5300 | -8.893 | -245 | 3.143.197 | ||||
| 2021-10-18 | 2021-10-18 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,1400 | -10.320 | -280 | 5.137.214 | ||||
| 2021-10-18 | 2021-10-15 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,0100 | -3.413 | -96 | 5.147.534 | ||||
| 2021-10-18 | 2021-10-15 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,5300 | -14.882 | -410 | 5.150.947 | ||||
| 2021-10-14 | 2021-10-14 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,3000 | -27.320 | -746 | 3.152.090 | ||||
| 2021-10-14 | 2021-10-13 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,1300 | -20.929 | -568 | 3.179.410 | ||||
| 2021-10-14 | 2021-10-12 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0900 | -8.521 | -231 | 3.200.339 | ||||
| 2021-10-14 | 2021-10-14 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,3000 | -27.320 | -746 | 3.152.090 | ||||
| 2021-10-14 | 2021-10-13 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,1300 | -20.929 | -568 | 3.179.410 | ||||
| 2021-10-14 | 2021-10-12 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0900 | -8.521 | -231 | 3.200.339 | ||||
| 2021-10-14 | 2021-10-14 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,3000 | -45.719 | -1.248 | 5.165.829 | ||||
| 2021-10-14 | 2021-10-13 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,1300 | -35.023 | -950 | 5.211.548 | ||||
| 2021-10-14 | 2021-10-12 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0900 | -14.260 | -386 | 5.246.571 | ||||
| 2021-10-12 | 2021-10-11 | 4 | Gall Matthew | ITOS | Stock Option (right to buy) | D | 6,16 | -14.429 | 42.388 | |||||
| 2021-10-12 | 2021-10-11 | 4 | Gall Matthew | ITOS | Common Stock | D | 6,1600 | 14.429 | 89 | 19.429 | ||||
| 2021-10-12 | 2021-10-11 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,2400 | -48.812 | -1.330 | 3.208.860 | ||||
| 2021-10-12 | 2021-10-08 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0100 | -2.032 | -55 | 3.257.672 | ||||
| 2021-10-12 | 2021-10-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0000 | -1.149 | -31 | 3.259.704 | ||||
| 2021-10-12 | 2021-10-11 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,2400 | -81.684 | -2.225 | 5.260.831 | ||||
| 2021-10-12 | 2021-10-08 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0100 | -3.400 | -92 | 5.342.515 | ||||
| 2021-10-12 | 2021-10-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0000 | -1.922 | -52 | 5.345.915 | ||||
| 2021-10-12 | 2021-10-11 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,2400 | -48.812 | -1.330 | 3.208.860 | ||||
| 2021-10-12 | 2021-10-08 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0100 | -2.032 | -55 | 3.257.672 | ||||
| 2021-10-12 | 2021-10-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0000 | -1.149 | -31 | 3.259.704 | ||||
| 2021-10-05 | 2021-10-04 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0600 | -20.711 | -560 | 3.260.853 | ||||
| 2021-10-05 | 2021-10-01 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0000 | -6.855 | -185 | 3.281.564 | ||||
| 2021-10-05 | 2021-10-04 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0600 | -34.659 | -938 | 5.347.837 | ||||
| 2021-10-05 | 2021-10-01 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0000 | -11.471 | -310 | 5.382.496 | ||||
| 2021-10-05 | 2021-10-04 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0600 | -20.711 | -560 | 3.260.853 | ||||
| 2021-10-05 | 2021-10-01 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0000 | -6.855 | -185 | 3.281.564 | ||||
| 2021-09-30 | 2021-09-30 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0000 | -2.292 | -62 | 3.288.419 | ||||
| 2021-09-30 | 2021-09-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0000 | -19.214 | -519 | 3.290.711 | ||||
| 2021-09-30 | 2021-09-30 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0000 | -2.292 | -62 | 3.288.419 | ||||
| 2021-09-30 | 2021-09-28 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0000 | -19.214 | -519 | 3.290.711 | ||||
| 2021-09-30 | 2021-09-30 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0000 | -3.836 | -104 | 5.393.967 | ||||
| 2021-09-30 | 2021-09-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0000 | -32.154 | -868 | 5.397.803 | ||||
| 2021-09-27 | 2021-09-27 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0900 | -19.455 | -527 | 5.429.957 | ||||
| 2021-09-27 | 2021-09-24 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,8100 | -8.221 | -229 | 5.449.412 | ||||
| 2021-09-27 | 2021-09-23 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,3800 | -1.200 | -34 | 5.457.633 | ||||
| 2021-09-27 | 2021-09-23 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,9600 | -60.600 | -1.694 | 5.458.833 | ||||
| 2021-09-27 | 2021-09-27 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0900 | -11.625 | -315 | 3.309.925 | ||||
| 2021-09-27 | 2021-09-24 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,8100 | -4.913 | -137 | 3.321.550 | ||||
| 2021-09-27 | 2021-09-23 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,3800 | -717 | -20 | 3.326.463 | ||||
| 2021-09-27 | 2021-09-23 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,9600 | -36.213 | -1.013 | 3.327.180 | ||||
| 2021-09-27 | 2021-09-24 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0180 | -1.089 | -31 | 99.026 | ||||
| 2021-09-27 | 2021-09-23 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,1590 | -5.322 | -150 | 100.115 | ||||
| 2021-09-27 | 2021-09-27 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0900 | -11.625 | -315 | 3.309.925 | ||||
| 2021-09-27 | 2021-09-24 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,8100 | -4.913 | -137 | 3.321.550 | ||||
| 2021-09-27 | 2021-09-23 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,3800 | -717 | -20 | 3.326.463 | ||||
| 2021-09-27 | 2021-09-23 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,9600 | -36.213 | -1.013 | 3.327.180 | ||||
| 2021-09-23 | 2021-09-22 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,5400 | -23.921 | -659 | 5.519.433 | ||||
| 2021-09-23 | 2021-09-21 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,4700 | -32.858 | -903 | 5.543.354 | ||||
| 2021-09-23 | 2021-09-22 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,5400 | -14.294 | -394 | 3.363.393 | ||||
| 2021-09-23 | 2021-09-21 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,4700 | -19.635 | -539 | 3.377.687 | ||||
| 2021-09-23 | 2021-09-22 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,5400 | -14.294 | -394 | 3.363.393 | ||||
| 2021-09-23 | 2021-09-21 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,4700 | -19.635 | -539 | 3.377.687 | ||||
| 2021-09-20 | 2021-09-20 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,8400 | -13.701 | -381 | 3.397.322 | ||||
| 2021-09-20 | 2021-09-20 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,0300 | -10.602 | -287 | 3.411.023 | ||||
| 2021-09-20 | 2021-09-17 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,8200 | -45.698 | -1.317 | 3.421.625 | ||||
| 2021-09-20 | 2021-09-16 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,4700 | -21.253 | -605 | 3.467.323 | ||||
| 2021-09-20 | 2021-09-20 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,8400 | -13.701 | -381 | 3.397.322 | ||||
| 2021-09-20 | 2021-09-20 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,0300 | -10.602 | -287 | 3.411.023 | ||||
| 2021-09-20 | 2021-09-17 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,8200 | -45.698 | -1.317 | 3.421.625 | ||||
| 2021-09-20 | 2021-09-16 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,4700 | -21.253 | -605 | 3.467.323 | ||||
| 2021-09-20 | 2021-09-20 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,8400 | -22.930 | -638 | 5.576.212 | ||||
| 2021-09-20 | 2021-09-20 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,0300 | -17.743 | -480 | 5.599.142 | ||||
| 2021-09-20 | 2021-09-17 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,8200 | -76.473 | -2.204 | 5.616.885 | ||||
| 2021-09-20 | 2021-09-16 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,4700 | -35.565 | -1.013 | 5.693.358 | ||||
| 2021-09-16 | 2021-09-15 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,1500 | -991 | -28 | 3.488.576 | ||||
| 2021-09-16 | 2021-09-15 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,7900 | -23.113 | -642 | 3.489.567 | ||||
| 2021-09-16 | 2021-09-14 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,9900 | -3.623 | -101 | 3.512.680 | ||||
| 2021-09-16 | 2021-09-14 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,5000 | -17.938 | -493 | 3.516.303 | ||||
| 2021-09-16 | 2021-09-15 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,1500 | -991 | -28 | 3.488.576 | ||||
| 2021-09-16 | 2021-09-15 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,7900 | -23.113 | -642 | 3.489.567 | ||||
| 2021-09-16 | 2021-09-14 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,9900 | -3.623 | -101 | 3.512.680 | ||||
| 2021-09-16 | 2021-09-14 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,5000 | -17.938 | -493 | 3.516.303 | ||||
| 2021-09-16 | 2021-09-15 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,1500 | -1.659 | -47 | 5.728.923 | ||||
| 2021-09-16 | 2021-09-15 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,7900 | -38.677 | -1.075 | 5.730.582 | ||||
| 2021-09-16 | 2021-09-14 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,9900 | -6.063 | -170 | 5.769.259 | ||||
| 2021-09-16 | 2021-09-14 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,5000 | -30.018 | -825 | 5.775.322 | ||||
| 2021-09-13 | 2021-09-13 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,6400 | -35.785 | -989 | 5.805.340 | ||||
| 2021-09-13 | 2021-09-10 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,7300 | -11.330 | -326 | 5.841.125 | ||||
| 2021-09-13 | 2021-09-10 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 27,8600 | -11.313 | -315 | 5.852.455 | ||||
| 2021-09-13 | 2021-09-09 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,9700 | -38.028 | -1.102 | 5.863.768 | ||||
| 2021-09-13 | 2021-09-13 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,6400 | -21.384 | -591 | 3.534.241 | ||||
| 2021-09-13 | 2021-09-10 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,7300 | -6.771 | -195 | 3.555.625 | ||||
| 2021-09-13 | 2021-09-10 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 27,8600 | -6.760 | -188 | 3.562.396 | ||||
| 2021-09-13 | 2021-09-09 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,9700 | -22.725 | -658 | 3.569.156 | ||||
| 2021-09-13 | 2021-09-13 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,6400 | -21.384 | -591 | 3.534.241 | ||||
| 2021-09-13 | 2021-09-10 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,7300 | -6.771 | -195 | 3.555.625 | ||||
| 2021-09-13 | 2021-09-10 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 27,8600 | -6.760 | -188 | 3.562.396 | ||||
| 2021-09-13 | 2021-09-09 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,9700 | -22.725 | -658 | 3.569.156 | ||||
| 2021-09-08 | 2021-09-08 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 29,1000 | -1.573 | -46 | 5.901.796 | ||||
| 2021-09-08 | 2021-09-08 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 28,6100 | -18.663 | -534 | 5.903.369 | ||||
| 2021-09-08 | 2021-09-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | -31.340 | 5.922.032 | ||||||
| 2021-09-08 | 2021-09-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 29,1800 | -50.996 | -1.488 | 5.953.372 | ||||
| 2021-09-08 | 2021-09-08 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 29,1000 | -940 | -27 | 3.591.881 | ||||
| 2021-09-08 | 2021-09-08 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 28,6100 | -11.152 | -319 | 3.592.821 | ||||
| 2021-09-08 | 2021-09-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | -31.340 | 3.603.793 | ||||||
| 2021-09-08 | 2021-09-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 29,1800 | -30.474 | -889 | 3.635.313 | ||||
| 2021-09-08 | 2021-09-08 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 29,1000 | -940 | -27 | 3.591.881 | ||||
| 2021-09-08 | 2021-09-08 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 28,6100 | -11.152 | -319 | 3.592.821 | ||||
| 2021-09-08 | 2021-09-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | -31.340 | 3.603.793 | ||||||
| 2021-09-08 | 2021-09-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 29,1800 | -30.474 | -889 | 3.635.313 | ||||
| 2021-09-03 | 2021-09-02 | 4 | Detheux Michel | ITOS | Common Stock | D | 29,4930 | -550 | -16 | 105.437 | ||||
| 2021-09-03 | 2021-09-02 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,9140 | -11.018 | -319 | 105.987 | ||||
| 2021-09-03 | 2021-09-01 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,2960 | -8.684 | -246 | 117.005 | ||||
| 2021-08-31 | 2021-08-31 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,1200 | -4.093 | -115 | 125.689 | ||||
| 2021-08-31 | 2021-08-30 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0100 | -2.322 | -65 | 129.782 | ||||
| 2021-08-31 | 2021-08-27 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,1700 | -8.248 | -232 | 132.104 | ||||
| 2021-08-25 | 2021-08-25 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0013 | -861 | -24 | 140.352 | ||||
| 2021-08-25 | 2021-08-24 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,2600 | -225 | -6 | 141.213 | ||||
| 2021-08-25 | 2021-08-23 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,0600 | -7.499 | -210 | 141.438 | ||||
| 2021-08-05 | 2021-07-30 | 4 | Call Matthew | ITOS | Stock Option (right to buy) | D | 2,95 | -53.672 | 148.090 | |||||
| 2021-08-05 | 2021-07-30 | 4 | Call Matthew | ITOS | Common Stock | D | 2,9500 | 53.672 | 158 | 53.672 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Gall Matthew | ITOS | Stock Option (Right to Buy) | D | 23,19 | 24.000 | 24.000 | |||||
| 2021-06-25 | 2021-06-24 | 4 | Call Matthew | ITOS | Stock Option (Right to Buy) | D | 23,19 | 72.000 | 72.000 | |||||
| 2021-06-25 | 2021-06-24 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 23,19 | 24.000 | 24.000 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Iannone Robert | ITOS | Stock Option (Right to Buy) | D | 26,03 | 4.560 | 4.560 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Biniszkiewicz Detlev | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 16.608 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Van Hauwermeiren Timothy | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 0 | |||||
| 2021-06-21 | 2021-06-17 | 4 | DiRocco Derek | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 0 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Ho Tony W | ITOS | Stock Option (Right to Buy) | D | 26,03 | 4.560 | 4.560 | |||||
| 2021-06-21 | 2021-06-17 | 4 | RODEN MATTHEW | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 0 | |||||
| 2021-06-21 | 2021-06-17 | 4 | RHOADS ANN D | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 16.608 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Davis Aaron I. | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 16.608 | |||||
| 2021-06-21 | 2021-06-17 | 4 | Hallal David | ITOS | Stock Option (Right to Buy) | D | 26,03 | 16.608 | 16.608 | |||||
| 2021-06-16 | 2021-06-14 | 4 | Detheux Michel | ITOS | Common Stock | D | 29,2605 | -3.937 | -115 | 148.937 | ||||
| 2021-06-16 | 2021-06-14 | 4 | Detheux Michel | ITOS | Common Stock | D | 28,3819 | -25.063 | -711 | 152.874 | ||||
| 2021-06-16 | 2021-06-16 | 4 | Gall Matthew | ITOS | Common Stock | D | 26,0893 | 5.000 | 130 | 5.000 | ||||
| 2021-06-10 | 2021-06-08 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -7.927 | 95.123 | |||||
| 2021-06-10 | 2021-06-08 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 20,0000 | -7.927 | -159 | 0 | ||||
| 2021-06-10 | 2021-06-08 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 7.927 | 34 | 7.927 | ||||
| 2021-06-03 | 2021-05-24 | 4/A | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -7.927 | 110.977 | |||||
| 2021-06-03 | 2021-05-24 | 4/A | McGrath Yvonne | ITOS | Common Stock | D | 21,9246 | -7.927 | -174 | 0 | ||||
| 2021-06-03 | 2021-05-24 | 4/A | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 7.927 | 34 | 7.927 | ||||
| 2021-06-03 | 2021-06-02 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -323 | 103.050 | |||||
| 2021-06-03 | 2021-06-02 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 20,0000 | -323 | -6 | 0 | ||||
| 2021-06-03 | 2021-06-02 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 323 | 1 | 323 | ||||
| 2021-06-03 | 2021-06-01 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -7.604 | 103.373 | |||||
| 2021-06-03 | 2021-06-01 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 20,1792 | -7.604 | -153 | 0 | ||||
| 2021-06-03 | 2021-06-01 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 7.604 | 32 | 7.604 | ||||
| 2021-05-26 | 2021-05-24 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -7.927 | 110.977 | |||||
| 2021-05-26 | 2021-05-24 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 21,9246 | -7.927 | -174 | 0 | ||||
| 2021-05-26 | 2021-05-24 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 7.927 | 34 | 7.927 | ||||
| 2021-05-19 | 2021-05-17 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 4,23 | -7.926 | 118.904 | |||||
| 2021-05-19 | 2021-05-17 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 26,0100 | -90 | -2 | 0 | ||||
| 2021-05-19 | 2021-05-17 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 25,4321 | -2.029 | -52 | 90 | ||||
| 2021-05-19 | 2021-05-17 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 24,4148 | -5.807 | -142 | 2.119 | ||||
| 2021-05-19 | 2021-05-17 | 4 | McGrath Yvonne | ITOS | Common Stock | D | 4,2300 | 7.926 | 34 | 7.926 | ||||
| 2021-05-03 | 2021-04-29 | 4 | Iannone Robert | ITOS | Stock Option (Right to Buy) | D | 24,11 | 33.217 | 0 | |||||
| 2021-05-03 | 2021-04-29 | 4 | Ho Tony W | ITOS | Stock Option (Right to Buy) | D | 24,11 | 33.217 | 0 | |||||
| 2021-04-13 | 2021-04-09 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 29,9900 | -119 | -4 | 3.665.787 | ||||
| 2021-04-13 | 2021-04-09 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 29,9900 | -119 | -4 | 3.665.787 | ||||
| 2021-04-13 | 2021-04-09 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 29,9900 | -200 | -6 | 6.004.368 | ||||
| 2021-04-09 | 2021-04-08 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 31,0100 | -414 | -13 | 6.004.568 | ||||
| 2021-04-09 | 2021-04-08 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 30,5100 | -31.890 | -973 | 6.004.982 | ||||
| 2021-04-09 | 2021-04-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | -15.670 | 6.036.872 | ||||||
| 2021-04-09 | 2021-04-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 33,8400 | -1.300 | -44 | 6.052.542 | ||||
| 2021-04-09 | 2021-04-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 32,8400 | -3.083 | -101 | 6.053.842 | ||||
| 2021-04-09 | 2021-04-07 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 32,0700 | -5.295 | -170 | 6.056.925 | ||||
| 2021-04-09 | 2021-04-08 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 31,0100 | -247 | -8 | 3.655.906 | ||||
| 2021-04-09 | 2021-04-08 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 30,5100 | -19.057 | -581 | 3.666.153 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | -15.670 | 3.685.210 | ||||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 33,8400 | -777 | -26 | 3.700.880 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 32,8400 | -1.842 | -60 | 3.701.657 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 32,0700 | -3.164 | -101 | 3.703.499 | ||||
| 2021-04-09 | 2021-04-08 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 31,0100 | -247 | -8 | 3.655.906 | ||||
| 2021-04-09 | 2021-04-08 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 30,5100 | -19.057 | -581 | 3.666.153 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | -15.670 | 3.685.210 | ||||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 33,8400 | -777 | -26 | 3.700.880 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 32,8400 | -1.842 | -60 | 3.701.657 | ||||
| 2021-04-09 | 2021-04-07 | 4 | MPM BIOVENTURES 2018, L.P. | ITOS | Common Stock | I | 32,0700 | -3.164 | -101 | 3.703.499 | ||||
| 2021-04-05 | 2021-04-01 | 4 | RA CAPITAL MANAGEMENT, LLC | ITOS | Common Stock | I | 34,1800 | 131.364 | 4.490 | 3.155.667 | ||||
| 2021-04-05 | 2021-04-01 | 4 | RA CAPITAL MANAGEMENT, LLC | ITOS | Common Stock | I | 34,1800 | 289.843 | 9.907 | 289.843 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 41,58 | 144.000 | 144.000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | McGrath Yvonne | ITOS | Stock Option (Right to Buy) | D | 41,58 | 45.000 | 45.000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Lager Joanne Jenkins | ITOS | Stock Option (Right to Buy) | D | 41,58 | 122.000 | 122.000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Call Matthew | ITOS | Stock Option (Right to Buy) | D | 41,58 | 72.000 | 72.000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Gall Matthew | ITOS | Stock Option (Right to Buy) | D | 41,58 | 72.000 | 72.000 | |||||
| 2020-11-12 | 2020-11-09 | 4 | RODEN MATTHEW | ITOS | Stock Option (Right to Buy) | D | 26,35 | 33.217 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | Biniszkiewicz Detlev | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | Van Hauwermeiren Timothy | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | Davis Aaron I. | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | RHOADS ANN D | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | GADICKE ANSBERT | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | Hallal David | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-10-21 | 2020-07-23 | 4/A | DiRocco Derek | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. | ITOS | Series B-2 Preferred Stock | I | -158.687 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. | ITOS | Series B-2 Preferred Stock | I | -9.593.086 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. See Footnotes | ITOS | Common Stock | I | 19,0000 | 23.552 | 447 | 72.243 | ||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. See Footnotes | ITOS | Common Stock | I | 19,0000 | 1.401.448 | 26.628 | 4.345.016 | ||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 48.691 | 48.691 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | Davis Aaron I. | ITOS | Common Stock | I | 2.943.568 | 2.943.568 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -2.600.628 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -29.440 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -79.281 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -1.491.666 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -81.295 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -157.529 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B-2 Preferred Stock | I | -2.361.805 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -4.211.330 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -47.674 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -128.384 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -2.415.530 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -131.645 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -255.094 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Series B Preferred Stock | I | -3.824.591 | 0 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 160.000 | 3.040 | 2.355.557 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 1.121 | 21 | 25.974 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 3.020 | 57 | 69.951 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 56.814 | 1.079 | 1.316.139 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 3.096 | 59 | 71.727 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 5.994 | 114 | 138.985 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 19,0000 | 89.955 | 1.709 | 2.083.887 | ||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 797.983 | 2.195.557 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 9.033 | 24.853 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 24.326 | 66.931 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 457.706 | 1.259.325 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 24.944 | 68.381 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 48.336 | 132.991 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 724.702 | 1.993.932 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 1.397.574 | 1.397.574 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 15.820 | 15.820 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 42.605 | 42.605 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 801.619 | 801.619 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 43.687 | 43.687 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 84.655 | 84.655 | ||||||
| 2020-07-30 | 2020-07-28 | 4 | GADICKE ANSBERT | ITOS | Common Stock | I | 1.269.230 | 1.269.230 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -29.440 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -79.281 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -1.491.666 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -81.295 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -157.529 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -2.361.805 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -47.674 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -128.384 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -2.415.530 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -131.645 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -255.094 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -3.824.591 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 1.121 | 21 | 25.974 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 3.020 | 57 | 69.951 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 56.814 | 1.079 | 1.316.139 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 3.096 | 59 | 71.727 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 5.994 | 114 | 138.985 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 89.955 | 1.709 | 2.083.887 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 9.033 | 24.853 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 24.326 | 66.931 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 457.706 | 1.259.325 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 24.944 | 68.381 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 48.336 | 132.991 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 724.702 | 1.993.932 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 15.820 | 15.820 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 42.605 | 42.605 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 801.619 | 801.619 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 43.687 | 43.687 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 84.655 | 84.655 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 1.269.230 | 1.269.230 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Series B-2 Preferred Stock | D | -158.687 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Series B-2 Preferred Stock | D | -9.593.086 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 19,0000 | 23.552 | 447 | 72.243 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 19,0000 | 1.401.448 | 26.628 | 4.345.016 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 48.691 | 48.691 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | Boxer Capital, LLC | ITOS | Common Stock | D | 2.943.568 | 2.943.568 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | RA CAPITAL MANAGEMENT, LLC | ITOS | Series B-2 Convertible Preferred Stock | I | -9.751.773 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | RA CAPITAL MANAGEMENT, LLC | ITOS | Common Stock | I | 19,0000 | 1.425.000 | 27.075 | 4.417.259 | ||||
| 2020-07-29 | 2020-07-28 | 4 | RA CAPITAL MANAGEMENT, LLC | ITOS | Common Stock | I | 2.992.259 | 2.992.259 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -29.440 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -79.281 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -1.491.666 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -81.295 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -157.529 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B-2 Preferred Stock | I | -2.361.805 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -47.674 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -128.384 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -2.415.530 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -131.645 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -255.094 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Series B Preferred Stock | I | -3.824.591 | 0 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 1.121 | 21 | 25.974 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 3.020 | 57 | 69.951 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 56.814 | 1.079 | 1.316.139 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 3.096 | 59 | 71.727 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 5.994 | 114 | 138.985 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 19,0000 | 89.955 | 1.709 | 2.083.887 | ||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 9.033 | 24.853 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 24.326 | 66.931 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 457.706 | 1.259.325 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 24.944 | 68.381 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 48.336 | 132.991 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 724.702 | 1.993.932 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 15.820 | 15.820 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 42.605 | 42.605 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 801.619 | 801.619 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 43.687 | 43.687 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 84.655 | 84.655 | ||||||
| 2020-07-29 | 2020-07-28 | 4 | MPM BioVentures 2014, L.P. | ITOS | Common Stock | I | 1.269.230 | 1.269.230 | ||||||
| 2020-07-24 | 2020-07-23 | 4 | Hallal David | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | Detheux Michel | ITOS | Stock Option (Right to Buy) | D | 19,00 | 1.035.424 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | Biniszkiewicz Detlev | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | Van Hauwermeiren Timothy | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | DiRocco Derek | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | RHOADS ANN D | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | GADICKE ANSBERT | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-24 | 2020-07-23 | 4 | Davis Aaron I. | ITOS | Stock Option (Right to Buy) | D | 19,00 | 16.608 | 0 | |||||
| 2020-07-23 | 3 | Detheux Michel | ITOS | Common Stock | D | 355.874 | ||||||||
| 2020-07-23 | 3 | Detheux Michel | ITOS | Common Stock | D | 355.874 | ||||||||
| 2020-07-23 | 3 | Detheux Michel | ITOS | Common Stock | D | 355.874 |
