| Deler fremragende | 4,872,497 shares |
| Insideraktier | 736.084 shares |
| Insider ejerskab | 15,11 % |
| Total Insiders | 41 |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Insiderhandelsdiagram
Calithera Biosciences, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Adage Capital Partners Gp, L.l.c.
10% Owner -
|
3.546.873 | 177.344 | |
| Sunil Agarwal Director - [D] | 0 | 0 | |
|
ATV Associates VIII, L.L.C.
10% Owner -
|
2.110.082 | 105.504 | |
|
Adage Capital Advisors, L.L.C.
10% Owner -
|
3.546.873 | 177.344 | |
|
Adage Capital Partners, L.P.
10% Owner -
|
3.546.873 | 177.344 | |
|
Advanced Technology Ventures VIII LP
10% Owner -
|
2.110.082 | 105.504 | |
|
Robert Atchinson
10% Owner -
|
3.546.873 | 177.344 | |
| Biotechnology Value Fund Ii Lp - | 480.432 | 24.022 | |
| Biotechnology Value Fund L P - | 480.432 | 24.022 | |
|
James J Bochnowski
10% Owner -
|
23.464 | 1.173 | |
|
Bvf Inc/il
10% Owner -
|
480.432 | 24.022 | |
|
Bvf Partners L P/il
10% Owner -
|
480.432 | 24.022 | |
| BVF Partners OS Ltd. - | 480.432 | 24.022 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
| Mark K Bennett SR. VP, RESEARCH - [O] | 10.413 | 521 | |
| Biotechnology Value Trading Fund OS LP - | 480.432 | 24.022 | |
|
Ralph E Christoffersen
Director, 10% Owner -
[D]
|
2.161.915 | 108.096 | |
|
Delphi Ventures Viii Lp
10% Owner -
|
23.464 | 1.173 | |
|
David L Douglass
10% Owner -
|
23.464 | 1.173 | |
| Jonathan G Drachman Director - [D] | 200.000 | 10.000 | |
|
Delphi BioInvestments VIII LP
10% Owner -
|
23.464 | 1.173 | |
|
Delphi Management Partners VIII, L.L.C.
10% Owner -
|
23.464 | 1.173 | |
| Garland J. Scott Director - [D] | 0 | 0 | |
|
Jean George
Director, 10% Owner -
[D]
|
2.110.082 | 105.504 | |
|
Phillip Gross
10% Owner -
|
3.546.873 | 177.344 | |
| Curtis Hecht CHIEF BUSINESS OFFICER - [O] | 92.321 | 4.616 | |
| Suzy Jones Director - [D] | 14.394 | 720 | |
| Emil Kuriakose CHIEF MEDICAL OFFICER - [O] | 3.539 | 3.539 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Mark N Lampert
10% Owner -
|
480.432 | 24.022 | |
|
Morgenthaler Venture Partners Ix Lp
10% Owner -
|
2.161.915 | 108.096 | |
| Christopher Molineaux SR. VP, DEVELOPMENT - [O] | 27.859 | 27.859 | |
| Susan Molineaux PRESIDENT & CEO, Director - [D] [O] | 27.859 | 27.859 | |
| Keith Orford Director - [O] | 66.094 | 3.305 | |
|
Deepika Pakianathan
Director, 10% Owner -
[D]
|
0 | 0 | |
| Francesco Parlati SR. VP, RESEARCH - [O] | 140.998 | 7.050 | |
|
Douglas A Roeder
10% Owner -
|
23.464 | 1.173 | |
| Sumita Ray See Remarks - [O] | 105.000 | 5.250 | |
| Eric Sjogren SR. VP, DRUG DISCOVERY - [O] | 8.467 | 8.467 | |
| Waddill William D. SR. VP & CFO - [O] | 17.485 | 874 | |
| Blake Wise Director - [D] | 0 | 0 | |
| Henry Ward Wolff Director - [D] | 0 | 0 | |
| Stephanie Wong See Remarks - [O] | 6.287 | 6.287 |
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i CALA / Calithera Biosciences, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i CALA / Calithera Biosciences, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 0,3858 | -1.172 | -0 | 0 | ||||
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 0,3858 | -120.161 | -46 | 0 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4461 | -317 | -0 | 6.287 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,4461 | -526 | -0 | 27.859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,4461 | -217 | -0 | 27.859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4461 | -79 | -0 | 3.539 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4461 | -279 | -0 | 8.467 | ||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 597.475 | 597.475 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215.000 | 215.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 40.000 | 40.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Kuriakose Emil | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215.000 | 215.000 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4915 | -4.794 | -2 | 172.434 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4915 | -666 | -0 | 67.369 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4915 | -5.586 | -3 | 132.085 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,4915 | -4.794 | -2 | 140.998 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 145.792 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 137.671 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 177.228 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,6604 | -3.855 | -3 | 68.035 | ||||
| 2021-11-12 | 2021-11-11 | 4 | Orford Keith | CALA | Common Stock | D | 0,8800 | -48.190 | -42 | 66.094 | ||||
| 2021-11-12 | 2021-11-10 | 4 | Orford Keith | CALA | Common Stock | D | 0,8565 | -30.000 | -26 | 114.284 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,8467 | 100.000 | 85 | 557.188 | ||||
| 2021-11-10 | 2021-11-10 | 4 | DRACHMAN JONATHAN G | CALA | Common Stock | D | 0,8595 | 200.000 | 172 | 200.000 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,8467 | 100.000 | 85 | 557.188 | ||||
| 2021-11-09 | 2021-11-09 | 4 | Orford Keith | CALA | Common Stock | D | 0,8400 | -51.810 | -44 | 144.284 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Orford Keith | CALA | Common Stock | D | 30.000 | 196.094 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12.000 | 102.500 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 195.305 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 210.871 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 155.748 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Wong Stephanie | CALA | Common Stock | D | 30.000 | 171.314 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Ray Sumita | CALA | Common Stock | D | 12.000 | 105.000 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,8700 | -3.077 | -3 | 69.390 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Kuriakose Emil | CALA | Common Stock | D | 12.000 | 72.467 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 163.869 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 179.435 | ||||||
| 2021-11-09 | 3 | Kuriakose Emil | CALA | Common Stock | D | 60.467 | ||||||||
| 2021-10-29 | 2021-10-28 | 4 | Sjogren Eric | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 180.871 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Sjogren Eric | CALA | Common Stock | D | 90.000 | 226.836 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Molineaux Christopher | CALA | Common Stock | D | 36.000 | 90.500 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Orford Keith | CALA | Common Stock | D | 90.000 | 166.094 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Wong Stephanie | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 141.314 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Wong Stephanie | CALA | Common Stock | D | 90.000 | 187.279 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Parlati Francesco | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 149.435 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Parlati Francesco | CALA | Common Stock | D | 90.000 | 195.400 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Ray Sumita | CALA | Common Stock | D | 36.000 | 93.000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 30.000 | 92.321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 35.000 | 62.321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12.000 | 52.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 30.000 | 40.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 375.000 | 375.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 85.000 | 95.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 12.000 | 57.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 30.000 | 45.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 30.000 | 76.094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 35.000 | 46.094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 105.400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 105.400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 134.336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 134.336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 30.000 | 103.156 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 35.000 | 73.156 | ||||||
| 2020-12-18 | 2020-12-16 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -2.447 | -15 | 11.094 | ||||
| 2020-08-04 | 2020-07-31 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 4,70 | 40.000 | 40.000 | |||||
| 2020-07-14 | 3 | Garland J. Scott | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2020-06-11 | 2020-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -192.250 | -1.154 | 480.432 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -1.064.332 | -6.386 | 2.766.561 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -1.027.016 | -6.162 | 3.712.340 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Wong Stephanie | CALA | Common Stock | D | 8,0000 | -5.000 | -40 | 30.082 | ||||
| 2020-02-24 | 2020-02-20 | 4 | Orford Keith | CALA | Common Stock | D | 8,0000 | -3.021 | -24 | 8.541 | ||||
| 2020-01-22 | 2020-01-18 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 400.000 | 400.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120.000 | 120.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120.000 | 120.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 75.000 | 75.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 7,41 | 140.000 | 140.000 | |||||
| 2019-12-26 | 2019-12-23 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -3.021 | -18 | 11.562 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 14.151 | 55 | 672.682 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 79.285 | 310 | 3.830.893 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 98.518 | 385 | 4.739.356 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 11.105 | 37 | 658.531 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 45.888 | 155 | 3.751.608 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 71.495 | 241 | 4.640.838 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 57.868 | 156 | 647.426 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 331.048 | 894 | 3.705.720 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 408.592 | 1.103 | 4.569.343 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 116.552 | 303 | 589.558 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 610.052 | 1.586 | 3.374.672 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 872.373 | 2.268 | 4.160.751 | ||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 3,8800 | 51.600 | 200 | 457.188 | ||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 3,8800 | 51.600 | 200 | 457.188 | ||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -21.739 | 0 | |||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,9600 | 21.739 | 21 | 72.057 | ||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -10.000 | 13.284 | |||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10.000 | 26 | 31.751 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -417 | -3 | 12.083 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -6.246 | 0 | |||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Common Stock | D | 2,6400 | 6.246 | 16 | 42.201 | ||||
| 2019-06-03 | 2019-05-30 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-05-24 | 2019-05-22 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -416 | -2 | 10.000 | ||||
| 2019-04-17 | 2019-04-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,3300 | -416 | -3 | 10.416 | ||||
| 2019-03-19 | 2019-03-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,4300 | -417 | -3 | 10.832 | ||||
| 2019-03-13 | 2019-03-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -1.565 | -9 | 11.249 | ||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | -12.986 | 395.588 | ||||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | -12.986 | 395.588 | ||||||
| 2019-01-14 | 2019-01-10 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 4,64 | 90.000 | 90.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 120.000 | 120.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 117.000 | 117.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 4,64 | 132.000 | 132.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 390.000 | 390.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 47.000 | 47.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 100.000 | 100.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 105.000 | 105.000 | |||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | -6.476 | 408.574 | ||||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | -6.476 | 408.574 | ||||||
| 2018-10-17 | 2018-10-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,0500 | -313 | -2 | 10.314 | ||||
| 2018-10-15 | 2018-10-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -1.252 | -8 | 10.627 | ||||
| 2018-10-11 | 2018-10-09 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 5,61 | 25.000 | 25.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -8.601 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -8.209 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4800 | 16.810 | 8 | 42.818 | ||||
| 2018-03-06 | 3/A | Parlati Francesco | CALA | Common Stock | D | 20.349 | ||||||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -3.116 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -1.979 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3.116 | 3 | 28.455 | ||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1.979 | 2 | 25.339 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -26.992 | 9.729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -6.798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 6.798 | 18 | 21.000 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -6.798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -26.992 | 9.729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 26.992 | 71 | 44.860 | ||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -10.000 | 21.596 | |||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10.000 | 26 | 15.000 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -3.116 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -1.979 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3.116 | 3 | 20.488 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1.979 | 2 | 17.372 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 60.000 | 60.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 65.000 | 65.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 200.000 | 200.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 30.000 | 30.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -5.300 | 34.030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -7.568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -2.700 | 6.006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 2.700 | 7 | 11.702 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 6.502 | 6 | 9.002 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -2.700 | 6.006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -5.300 | 34.030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -7.568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 5.300 | 14 | 15.368 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 7.568 | 7 | 10.068 | ||||
| 2017-10-03 | 3 | Ray Sumita | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-10-03 | 2017-09-29 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 15,75 | 75.000 | 75.000 | |||||
| 2017-10-03 | 2017-09-20 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 15,75 | 22.000 | 22.000 | |||||
| 2017-09-28 | 2017-09-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5000 | -38.000 | -589 | 3.546.873 | ||||
| 2017-09-28 | 2017-09-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5900 | -186.000 | -2.900 | 3.584.873 | ||||
| 2017-09-28 | 2017-09-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 15,6800 | -352.000 | -5.519 | 3.770.873 | ||||
| 2017-09-21 | 3 | Wise Blake | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-07-19 | 2017-07-17 | 4 | Wong Stephanie By Trust | CALA | Common Stock | I | 18,4078 | -3.552 | -65 | 10.550 | ||||
| 2017-07-19 | 2017-07-17 | 4 | Orford Keith | CALA | Common Stock | D | 18,3126 | -2.120 | -39 | 6.879 | ||||
| 2017-07-07 | 2017-07-06 | 4 | Hecht Curtis | CALA | Common Stock | D | 18,0000 | -700 | -13 | 15.940 | ||||
| 2017-06-13 | 2017-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-05-23 | 2017-05-19 | 4 | Hecht Curtis | CALA | Common Stock | D | 16,0000 | -650 | -10 | 14.910 | ||||
| 2017-03-24 | 2017-03-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,2500 | 487.804 | 5.000 | 4.122.873 | ||||
| 2017-03-15 | 2017-03-13 | 4 | Hecht Curtis | CALA | Common Stock | D | 14,0000 | -600 | -8 | 15.560 | ||||
| 2017-03-06 | 2017-03-02 | 4 | Hecht Curtis | CALA | Common Stock | D | 12,0000 | -550 | -7 | 16.160 | ||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24.764 | ||||||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24.764 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28.204 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28.204 | ||||||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 9.498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -5.418 | 6.502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -15.627 | 42.021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.306 | 7.568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 15.627 | 41 | 23.810 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6.306 | 6 | 8.183 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -15.627 | 42.021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.306 | 7.568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 9.498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -5.418 | 6.502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 12.044 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5.418 | 5 | 7.295 | ||||
| 2016-12-01 | 2016-11-29 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 165.000 | 165.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 56.250 | 56.250 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-11-17 | 2016-11-16 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 3,1500 | 500.000 | 1.575 | 3.635.069 | ||||
| 2016-10-03 | 2016-09-29 | 4 | Waddill William D. | CALA | Common Stock | D | -17.485 | 17.485 | ||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14.394 | ||||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14.394 | ||||||||
| 2016-08-11 | 2016-08-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 3,26 | 22.000 | 22.000 | |||||
| 2016-08-10 | 2016-08-08 | 4 | Hecht Curtis | CALA | Common Stock | D | 3.085 | 14.210 | ||||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 14.247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -7.586 | 11.920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -16.146 | 47.919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -8.829 | 13.874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -4.410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 16.146 | 43 | 31.885 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 8.829 | 8 | 15.739 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4.410 | 2 | 6.910 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -16.146 | 47.919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -8.829 | 13.874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -4.410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 14.247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -7.586 | 11.920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 14.835 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 7.586 | 7 | 10.086 | ||||
| 2016-06-16 | 2016-06-14 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4.240 | ||||||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4.240 | ||||||||
| 2016-05-03 | 2016-05-02 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 5,33 | 5.000 | 5.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 32.500 | 32.500 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 185.000 | 185.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | -4.749 | 18.998 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | -2.835 | 8.034 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -1.612 | 807 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -1.217 | 0 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 10.413 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 2.835 | 3 | 5.664 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1.612 | 1 | 2.829 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1.217 | 1 | 1.217 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 18.996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -5.418 | 19.506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -11.640 | 73.794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.306 | 22.703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -5.512 | 4.410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -4.367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 11.640 | 31 | 109.112 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6.306 | 6 | 97.472 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 5.512 | 3 | 91.166 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4.367 | 2 | 85.654 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -11.640 | 73.794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.306 | 22.703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -5.512 | 4.410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -4.367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 18.996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -5.418 | 19.506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 39.542 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5.418 | 5 | 34.793 | ||||
| 2015-11-18 | 2015-11-16 | 4 | Hecht Curtis | CALA | Common Stock | D | 6,5820 | -970 | -6 | 8.625 | ||||
| 2015-09-30 | 3 | AGARWAL SUNIL | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2015-09-30 | 2015-09-29 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,00 | 22.000 | 22.000 | |||||
| 2015-09-24 | 2015-09-23 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0687 | 40.168 | 244 | 3.135.069 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0033 | 41.800 | 251 | 3.094.901 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9977 | 25.000 | 150 | 3.053.101 | ||||
| 2015-09-08 | 2015-09-04 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,9500 | 2.300 | 14 | 3.028.101 | ||||
| 2015-09-08 | 2015-09-03 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9300 | 88.000 | 522 | 3.025.801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 22.000 | 123 | 2.937.801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5500 | 20.700 | 115 | 2.915.801 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,3500 | 32.400 | 173 | 2.895.101 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,1700 | 29.089 | 150 | 2.862.701 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 19.578 | 109 | 2.833.612 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4300 | 6.253 | 34 | 2.814.034 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4100 | 9.848 | 53 | 2.807.781 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 4,6500 | 32.058 | 149 | 2.797.933 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 4,7000 | 200 | 1 | 2.765.875 | ||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 2,64 | -2.000 | 43.378 | |||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 2,6400 | 2.000 | 5 | 8.625 | ||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | -13.125 | 61.880 | |||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Common Stock | D | 2,6400 | 13.125 | 35 | 15.625 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | -10.288 | 23.745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | -14.087 | 24.924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 2,64 | -30.279 | 85.434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,96 | -16.396 | 29.009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | -14.330 | 9.922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | -15.282 | 4.367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 30.279 | 80 | 78.787 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 16.396 | 16 | 48.508 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 14.330 | 7 | 32.112 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 15.282 | 7 | 17.782 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | -30.279 | 85.434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | -16.396 | 29.009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | -14.330 | 9.922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | -15.282 | 4.367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 2,64 | -10.288 | 23.745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 0,96 | -14.087 | 24.924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 10.288 | 27 | 26.875 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 14.087 | 14 | 16.587 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | -7.912 | 23.747 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | -4.726 | 10.869 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -2.688 | 2.419 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -3.039 | 1.217 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 7.912 | 21 | 19.501 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 4.726 | 5 | 11.589 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 2.688 | 1 | 6.863 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 3.039 | 1 | 4.175 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 33.000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 11.000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 39.355 | |||||
| 2015-06-10 | 2015-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 11.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 16,40 | 227.346 | 227.346 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 16,40 | 25.000 | 25.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Sjogren Eric | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 7,20 | 1.171 | 17.569 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | 5.626 | 75.005 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 7,2000 | 1.171 | 8 | 16.172 | ||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 2,6400 | 5.626 | 15 | 15.001 | ||||
| 2014-12-09 | 3 | Wolff Henry Ward | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2014-12-09 | 2014-12-02 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 9,64 | 22.000 | 22.000 | |||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,8000 | 25.000 | 170 | 2.765.675 | ||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,2500 | 13.000 | 94 | 2.740.675 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,9900 | 25.000 | 175 | 2.727.375 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,0000 | 30.000 | 210 | 2.702.375 | ||||
| 2014-10-15 | 2014-10-13 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 6,9400 | 88.700 | 616 | 2.672.375 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7.282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745.825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7.228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740.312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4.053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415.128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6.808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4.835 | 48 | 23.464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495.165 | 4.952 | 2.403.238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18.629 | 18.629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1.908.073 | 1.908.073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES D PREFERRED STOCK | I | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES C PREFERRED STOCK | I | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES B PREFERRED STOCK | I | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES A PREFERRED STOCK | I | 9.166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 10,0000 | 300.000 | 3.000 | 2.110.082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 1.810.082 | 1.810.082 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES D PREFERRED STOCK | I | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES C PREFERRED STOCK | I | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES B PREFERRED STOCK | I | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES A PREFERRED STOCK | I | 10.999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 10,0000 | 350.000 | 3.500 | 2.161.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 1.811.915 | 1.811.915 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES D PREFERRED STOCK | D | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES C PREFERRED STOCK | D | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES B PREFERRED STOCK | D | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES A PREFERRED STOCK | D | 10.999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 350.000 | 3.500 | 2.161.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 1.811.915 | 18.119 | 1.811.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7.282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745.825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7.228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740.312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4.053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415.128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6.808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4.835 | 48 | 23.464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495.165 | 4.952 | 2.403.238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18.629 | 18.629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1.908.073 | 1.908.073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES D PREFERRED STOCK | D | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES C PREFERRED STOCK | D | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES B PREFERRED STOCK | D | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES A PREFERRED STOCK | D | 9.166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 10,0000 | 300.000 | 3.000 | 2.110.082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 1.810.082 | 1.810.082 | ||||||
| 2014-10-03 | 2014-10-01 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,0000 | 800.000 | 8.000 | 2.583.675 | ||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18.750 | ||||||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18.750 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8.250 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8.250 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128.962 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63.108 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63.108 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23.262 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23.262 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
