| Deler fremragende | 168,712,220 shares |
| Insideraktier | 47.784.968 shares |
| Insider ejerskab | 28,32 % |
| Total Insiders | 51 |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Insiderhandelsdiagram
ACADIA Pharmaceuticals Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
14159, L.p.
Director, 10% Owner -
[D]
|
71.647 | 71.647 | |
|
667, L.p.
Director, 10% Owner -
[D]
|
38.452.877 | 39.365.965 | |
| Thomas H Aasen EXEC VP, CFO AND CBO - [O] | 0 | 0 | |
|
Baker Bros. Advisors Lp
Director, 10% Owner -
[D]
|
39.365.965 | 39.365.965 | |
|
Felix Baker
10% Owner -
|
38.452.877 | 39.365.965 | |
|
Julian Baker
10% Owner -
|
38.452.877 | 39.365.965 | |
|
Jeffrey T Barnes
10% Owner -
|
236.500 | 3.160.238 | |
| Michael T Borer Director - [D] | 0 | 0 | |
| Glenn Baity EVP AND GC - [O] | 83.734 | 83.734 | |
|
Baker Bros. Advisors (GP) LLC
Director, 10% Owner -
[D]
|
38.452.877 | 39.365.965 | |
|
Baker Brothers Life Sciences LP
Director, 10% Owner -
[D]
|
38.452.877 | 39.365.965 | |
| Stephen R Biggar | 0 | ||
| Gordon M Binder | 6.500 | ||
| Laura Brege Director - [D] | 15.095 | 15.095 | |
|
Mark Carthy
10% Owner -
|
236.500 | 3.160.238 | |
| Stephen Davis CEO, Director - [D] [O] | 186.555 | 186.555 | |
| James M Daly Director - [D] | 34.041 | 34.041 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Jonathan Fleming
10% Owner -
|
236.500 | 3.160.238 | |
| Garofalo Elizabeth A. Director - [D] | 25.382 | 25.382 | |
| Carl L Gordon Director - [D] | 774.006 | 774.006 | |
| Mary Ann Gray Director - [D] | 149.476 | 149.476 | |
| Edmund Harrigan Director - [D] | 35.041 | 35.041 | |
| Uli Hacksell CEO, Director - [D] [O] | 115.549 | 115.549 | |
| Leslie L Iversen Director - [D] | 36.127 | 36.127 | |
| Lester J Ph D Kaplan Director - [D] | 17.000 | 17.000 | |
| Kim Austin D. EVP,General Counsel, Secretary - [O] | 46.901 | 46.901 | |
| James Kihara PRINCIPAL ACCOUNTING OFFICER - [O] | 20.395 | 20.395 | |
|
Michael Lytton
10% Owner -
|
236.500 | 3.160.238 | |
|
Mrna Fund Ii Lp
10% Owner -
|
236.500 | ||
| Eric Alejandro Miller Controller & PAO - [O] | 270 | 270 | |
| Roger Mills EVP, DEVELOPMENT AND CMO - [O] | 18.550 | 18.550 | |
| Terrence O Moore EVP, CHIEF COMMERCIAL OFFICER - [O] | 1.671 | 1.671 | |
|
Nomura International Plc
10% Owner -
|
2.199.010 | 2.199.010 | |
| Adora Ndu Director - [D] | 24.801 | 24.801 |
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|---|---|---|
|
Nomura Phase4 Ventures GP LTD
10% Owner -
|
2.199.010 | 2.199.010 | |
|
Nomura Phase4 Ventures LP
10% Owner -
|
2.199.010 | 2.199.010 | |
|
Phase4 Ventures LTD Nomura
10% Owner -
|
2.199.010 | 2.199.010 | |
|
Obp Management Iv Lp
10% Owner -
|
236.500 | 3.160.238 | |
|
Oxford Bioscience Partners Iv Lp
10% Owner -
|
3.160.238 | 3.160.238 | |
| Torsten Rasmussen Director - [D] | 8.500 | 8.500 | |
| Elena Ridloff EVP and CFO - [O] | 10.553 | 10.553 | |
| Daniel B Soland Director - [D] | 44.041 | 44.041 | |
| Schneyer Mark C. EVP, CHIEF FINANCIAL OFFICER - [O] | 40.130 | 40.130 | |
| Stankovic Srdjan R. President - [O] | 61.234 | 61.234 | |
| Brendan Teehan EVP, COO, HEAD OF COMMERCIAL - [O] | 62.105 | 62.105 | |
| Bo-Ragnar Tolf | 21.000 | ||
|
Alan G Walton
Director, 10% Owner -
[D]
|
8.833 | 3.160.238 | |
| William McDowall Wells Director - [D] | 0 | 0 | |
| Yang Michael J. EVP and CCO - [O] | 8.059 | 8.059 | |
| Young Todd S. | 4.688 | ||
| Osch Martien van Director - [D] | 1.168.892 | 1.168.892 |
Report errors via our new Insider Auditing Tool
Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i ACAD / ACADIA Pharmaceuticals Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i ACAD / ACADIA Pharmaceuticals Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-09-03 | 2025-09-02 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 25,9753 | -1.600 | -42 | 25.382 | ||||
| 2025-08-19 | 2025-08-18 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 25,1829 | -22.000 | -554 | 40.130 | ||||
| 2025-06-05 | 2025-06-04 | 4 | Brege Laura | ACAD | Common Stock | D | 21,7800 | -14.446 | -315 | 15.095 | ||||
| 2025-06-02 | 2025-05-29 | 4 | Brege Laura | ACAD | Common Stock | D | 9.387 | 29.541 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | Daly James M | ACAD | Common Stock | D | 9.387 | 34.041 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 9.387 | 26.982 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | Ndu Adora | ACAD | Common Stock | D | 9.387 | 24.801 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 9.387 | 35.041 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 9.387 | 44.041 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 16.214 | 39.365.965 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 16.214 | 39.365.965 | ||||||
| 2025-05-19 | 2025-05-16 | 4 | Kihara James | ACAD | Common Stock | D | 20,0000 | -2.000 | -40 | 20.395 | ||||
| 2025-05-19 | 2025-05-16 | 4 | Kihara James | ACAD | Common Stock | D | 25,0000 | -2.000 | -50 | 22.395 | ||||
| 2025-05-19 | 2025-05-16 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 25,0000 | -2.000 | -50 | 62.130 | ||||
| 2025-05-02 | 2025-05-02 | 4 | Kihara James | ACAD | Common Stock | D | 14,6000 | -1.327 | -19 | 23.526 | ||||
| 2025-05-02 | 2025-05-01 | 4 | Kihara James | ACAD | Common Stock | D | 2.596 | 24.853 | ||||||
| 2025-05-02 | 2025-05-02 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 14,6000 | -3.498 | -51 | 62.773 | ||||
| 2025-05-02 | 2025-05-01 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 6.815 | 66.271 | ||||||
| 2025-04-08 | 2025-04-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 14,8200 | -2.708 | -40 | 59.456 | ||||
| 2025-04-08 | 2025-04-05 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 5.275 | 62.164 | ||||||
| 2025-04-08 | 2025-04-08 | 4 | Kihara James | ACAD | Common Stock | D | 14,8200 | -1.028 | -15 | 22.257 | ||||
| 2025-04-08 | 2025-04-05 | 4 | Kihara James | ACAD | Common Stock | D | 2.010 | 23.285 | ||||||
| 2025-03-26 | 2025-03-26 | 4 | Kihara James | ACAD | Common Stock | D | 17,0500 | -1.095 | -19 | 21.275 | ||||
| 2025-03-26 | 2025-03-25 | 4 | Kihara James | ACAD | Common Stock | D | 2.142 | 22.370 | ||||||
| 2025-03-26 | 2025-03-26 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 17,0500 | -3.171 | -54 | 56.889 | ||||
| 2025-03-26 | 2025-03-25 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 6.178 | 60.060 | ||||||
| 2025-03-06 | 2025-03-05 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 18,2300 | -4.919 | -90 | 17.595 | ||||
| 2025-02-25 | 2025-02-24 | 4 | Kihara James | ACAD | Common Stock | D | 19,9600 | -475 | -9 | 20.228 | ||||
| 2025-02-25 | 2025-02-23 | 4 | Kihara James | ACAD | Common Stock | D | 840 | 20.703 | ||||||
| 2025-02-25 | 2025-02-24 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 19,9600 | -773 | -15 | 53.882 | ||||
| 2025-02-25 | 2025-02-23 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.353 | 54.655 | ||||||
| 2024-11-19 | 2024-11-19 | 4 | Teehan Brendan | ACAD | Common Stock | D | 16,8100 | -10.329 | -174 | 62.105 | ||||
| 2024-11-19 | 2024-11-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 9.913 | 72.434 | ||||||
| 2024-11-19 | 2024-11-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 9.913 | 72.434 | ||||||
| 2024-11-19 | 2024-11-19 | 4 | Kihara James | ACAD | Common Stock | D | 16,8100 | -4.073 | -68 | 19.863 | ||||
| 2024-11-19 | 2024-11-17 | 4 | Kihara James | ACAD | Common Stock | D | 3.965 | 23.936 | ||||||
| 2024-11-19 | 2024-11-17 | 4 | Kihara James | ACAD | Common Stock | D | 3.965 | 23.936 | ||||||
| 2024-11-19 | 2024-11-19 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 16,8100 | -10.259 | -172 | 53.302 | ||||
| 2024-11-19 | 2024-11-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 9.913 | 63.561 | ||||||
| 2024-11-19 | 2024-11-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 9.913 | 63.561 | ||||||
| 2024-10-15 | 2024-10-12 | 4 | Ndu Adora | ACAD | Common Stock | D | 4.381 | 15.414 | ||||||
| 2024-08-20 | 2024-08-19 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 15,2800 | -9.733 | -149 | 43.735 | ||||
| 2024-08-20 | 2024-08-16 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 13.629 | 53.468 | ||||||
| 2024-08-20 | 2024-08-16 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 5.275 | 39.839 | ||||||
| 2024-08-20 | 2024-08-19 | 4 | Teehan Brendan | ACAD | Common Stock | D | 15,2800 | -9.534 | -146 | 52.177 | ||||
| 2024-08-20 | 2024-08-16 | 4 | Teehan Brendan | ACAD | Common Stock | D | 13.629 | 61.711 | ||||||
| 2024-08-20 | 2024-08-16 | 4 | Teehan Brendan | ACAD | Common Stock | D | 5.024 | 48.082 | ||||||
| 2024-08-20 | 2024-08-19 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15,2800 | -31.747 | -485 | 186.555 | ||||
| 2024-08-20 | 2024-08-16 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 44.782 | 218.302 | ||||||
| 2024-08-20 | 2024-08-16 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17.333 | 173.520 | ||||||
| 2024-06-11 | 2024-06-10 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 14,7900 | -975 | -14 | 34.564 | ||||
| 2024-06-11 | 2024-06-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.893 | 35.539 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | Brege Laura | ACAD | Common Stock | D | 6.652 | 20.154 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 6.652 | 34.654 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 6.652 | 25.654 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 6.652 | 22.514 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | Daly James M | ACAD | Common Stock | D | 6.652 | 24.654 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | Ndu Adora | ACAD | Common Stock | D | 6.652 | 11.033 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 18.774 | 39.349.751 | ||||||
| 2024-05-31 | 2024-05-29 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 18.774 | 39.349.751 | ||||||
| 2024-05-03 | 2024-05-02 | 4 | Kihara James | ACAD | Common Stock | D | 16,9400 | -1.326 | -22 | 14.370 | ||||
| 2024-05-03 | 2024-05-01 | 4 | Kihara James | ACAD | Common Stock | D | 2.596 | 15.696 | ||||||
| 2024-05-03 | 2024-05-02 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 16,9400 | -11.427 | -194 | 155.231 | ||||
| 2024-05-03 | 2024-05-01 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 22.391 | 166.658 | ||||||
| 2024-05-03 | 2024-05-02 | 4 | Teehan Brendan | ACAD | Common Stock | D | 16,9400 | -3.477 | -59 | 42.133 | ||||
| 2024-05-03 | 2024-05-01 | 4 | Teehan Brendan | ACAD | Common Stock | D | 6.814 | 45.610 | ||||||
| 2024-05-03 | 2024-05-02 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 16,9400 | -3.503 | -59 | 32.053 | ||||
| 2024-05-03 | 2024-05-01 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 6.814 | 35.556 | ||||||
| 2024-04-09 | 2024-04-08 | 4 | Kihara James | ACAD | Common Stock | D | 17,8700 | -762 | -14 | 13.100 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Kihara James | ACAD | Common Stock | D | 17,8700 | -1.028 | -18 | 13.862 | ||||
| 2024-04-09 | 2024-04-07 | 4 | Kihara James | ACAD | Common Stock | D | 1.489 | 14.890 | ||||||
| 2024-04-09 | 2024-04-05 | 4 | Kihara James | ACAD | Common Stock | D | 2.010 | 13.401 | ||||||
| 2024-04-09 | 2024-04-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 17,8700 | -2.716 | -49 | 28.742 | ||||
| 2024-04-09 | 2024-04-05 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 5.275 | 31.458 | ||||||
| 2024-04-09 | 2024-04-08 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17,8700 | -17.716 | -317 | 144.267 | ||||
| 2024-04-09 | 2024-04-08 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17,8700 | -8.858 | -158 | 161.983 | ||||
| 2024-04-09 | 2024-04-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 34.666 | 170.841 | ||||||
| 2024-04-09 | 2024-04-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17.333 | 136.175 | ||||||
| 2024-04-09 | 2024-04-08 | 4 | Teehan Brendan | ACAD | Common Stock | D | 17,8700 | -2.568 | -46 | 38.796 | ||||
| 2024-04-09 | 2024-04-05 | 4 | Teehan Brendan | ACAD | Common Stock | D | 5.024 | 41.364 | ||||||
| 2024-03-27 | 2024-03-27 | 4 | Teehan Brendan | ACAD | Common Stock | D | 17,9000 | -5.140 | -92 | 36.340 | ||||
| 2024-03-27 | 2024-03-25 | 4 | Teehan Brendan | ACAD | Common Stock | D | 10.048 | 41.480 | ||||||
| 2024-03-27 | 2024-03-27 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17,9000 | -17.714 | -317 | 118.842 | ||||
| 2024-03-27 | 2024-03-25 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 34.666 | 136.556 | ||||||
| 2024-03-27 | 2024-03-27 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 17,9000 | -5.434 | -97 | 26.183 | ||||
| 2024-03-27 | 2024-03-25 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 10.550 | 31.617 | ||||||
| 2024-02-27 | 2024-02-26 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 24,6700 | -772 | -19 | 21.067 | ||||
| 2024-02-27 | 2024-02-23 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.353 | 21.839 | ||||||
| 2024-02-27 | 2024-02-26 | 4 | Teehan Brendan | ACAD | Common Stock | D | 24,6700 | -624 | -15 | 31.432 | ||||
| 2024-02-27 | 2024-02-23 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.107 | 32.056 | ||||||
| 2024-02-27 | 2024-02-26 | 4 | Kihara James | ACAD | Common Stock | D | 24,6700 | -474 | -12 | 11.391 | ||||
| 2024-02-27 | 2024-02-23 | 4 | Kihara James | ACAD | Common Stock | D | 840 | 11.865 | ||||||
| 2024-02-27 | 2024-02-26 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 24,6700 | -5.577 | -138 | 101.890 | ||||
| 2024-02-27 | 2024-02-23 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 10.946 | 107.467 | ||||||
| 2024-01-09 | 2024-01-08 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 29,9600 | -590 | -18 | 46.901 | ||||
| 2024-01-09 | 2024-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 1.634 | 47.491 | ||||||
| 2024-01-09 | 2024-01-08 | 4 | Teehan Brendan | ACAD | Common Stock | D | 29,9600 | -731 | -22 | 30.949 | ||||
| 2024-01-09 | 2024-01-06 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.287 | 31.680 | ||||||
| 2024-01-09 | 2024-01-08 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 29,9600 | -3.732 | -112 | 96.521 | ||||
| 2024-01-09 | 2024-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 9.528 | 100.253 | ||||||
| 2023-12-15 | 2023-12-15 | 4 | Kihara James | ACAD | Common Stock | D | 28,3000 | -2.000 | -57 | 11.025 | ||||
| 2023-11-28 | 2023-11-24 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | -2.918 | 15.862 | ||||||
| 2023-11-21 | 2023-11-20 | 4 | Kihara James | ACAD | Common Stock | D | 22,6400 | -1.985 | -45 | 13.025 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Kihara James | ACAD | Common Stock | D | 1.982 | 15.010 | ||||||
| 2023-11-21 | 2023-11-17 | 4 | Kihara James | ACAD | Common Stock | D | 1.982 | 15.010 | ||||||
| 2023-11-21 | 2023-11-20 | 4 | Teehan Brendan | ACAD | Common Stock | D | 22,6400 | -4.960 | -112 | 30.393 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 4.956 | 35.353 | ||||||
| 2023-11-21 | 2023-11-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 4.956 | 35.353 | ||||||
| 2023-11-21 | 2023-11-20 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 22,6400 | -5.108 | -116 | 20.486 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 4.956 | 25.594 | ||||||
| 2023-11-21 | 2023-11-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 4.956 | 25.594 | ||||||
| 2023-10-16 | 2023-10-12 | 4 | Ndu Adora | ACAD | Common Stock | D | 4.381 | 4.381 | ||||||
| 2023-10-06 | 2023-10-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 21,9600 | -51.563 | -1.132 | 89.131 | ||||
| 2023-10-06 | 2023-10-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 103.999 | 140.694 | ||||||
| 2023-10-06 | 2023-10-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 21,9600 | -16.369 | -359 | 45.857 | ||||
| 2023-10-06 | 2023-10-05 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 36.174 | 62.226 | ||||||
| 2023-09-19 | 2023-09-15 | 4 | Kihara James | ACAD | Common Stock | D | 25,8800 | -2.000 | -52 | 10.778 | ||||
| 2023-08-23 | 2023-08-21 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 28,9970 | -10.000 | -290 | 15.682 | ||||
| 2023-07-18 | 2023-07-14 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 30,0435 | -100.000 | -3.004 | 36.695 | ||||
| 2023-07-18 | 2023-07-14 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 20,7700 | 100.000 | 2.077 | 136.695 | ||||
| 2023-07-13 | 2023-07-12 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 25,0517 | -55.104 | -1.380 | 36.695 | ||||
| 2023-07-13 | 2023-07-11 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 25,0000 | -16.498 | -412 | 91.799 | ||||
| 2023-06-16 | 2023-06-15 | 4 | Kihara James | ACAD | Common Stock | D | 24,1500 | -2.000 | -48 | 9.144 | ||||
| 2023-06-14 | 2023-06-12 | 4 | Brege Laura | ACAD | Common Stock | D | 24,8680 | -4.500 | -112 | 13.502 | ||||
| 2023-06-12 | 2023-06-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 25,0200 | -974 | -24 | 22.824 | ||||
| 2023-06-12 | 2023-06-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.893 | 23.798 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 8.552 | 28.002 | ||||||
| 2023-06-05 | 2022-06-07 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 6.391 | 19.450 | ||||||
| 2023-06-05 | 2021-06-22 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 3.059 | 13.059 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | Brege Laura | ACAD | Common Stock | D | 8.552 | 18.002 | ||||||
| 2023-06-05 | 2022-06-07 | 4 | Brege Laura | ACAD | Common Stock | D | 6.391 | 9.450 | ||||||
| 2023-06-05 | 2021-06-22 | 4 | Brege Laura | ACAD | Common Stock | D | 3.059 | 3.059 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 8.552 | 19.002 | ||||||
| 2023-06-05 | 2022-06-07 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 6.391 | 10.450 | ||||||
| 2023-06-05 | 2021-06-22 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 3.059 | 4.059 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | Daly James M | ACAD | Common Stock | D | 8.552 | 18.002 | ||||||
| 2023-06-05 | 2022-06-07 | 4 | Daly James M | ACAD | Common Stock | D | 6.391 | 9.450 | ||||||
| 2023-06-05 | 2021-06-22 | 4 | Daly James M | ACAD | Common Stock | D | 3.059 | 3.059 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 8.552 | 18.780 | ||||||
| 2023-06-05 | 2022-09-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 1.919 | 10.228 | ||||||
| 2023-06-05 | 2022-06-07 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 6.391 | 8.309 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 13.304 | 39.330.977 | ||||||
| 2023-06-05 | 2023-06-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 13.304 | 39.330.977 | ||||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,6500 | 259.109 | 6.646 | 39.317.673 | ||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,6500 | 24.113 | 618 | 3.610.443 | ||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,5138 | 28.878 | 737 | 39.058.564 | ||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,5138 | 2.688 | 69 | 3.586.330 | ||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,2723 | 218.171 | 5.514 | 39.029.686 | ||||
| 2023-05-24 | 2023-05-24 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,2723 | 20.304 | 513 | 3.583.642 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,5400 | 74.582 | 1.905 | 38.811.515 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,5400 | 6.941 | 177 | 3.563.338 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,3302 | 116.672 | 2.955 | 38.736.933 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,3302 | 10.858 | 275 | 3.556.397 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17,0100 | 12.500 | 213 | 38.620.261 | ||||
| 2023-05-24 | 2023-05-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17,0100 | 12.500 | 213 | 38.620.261 | ||||
| 2023-05-24 | 2023-05-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 24,8000 | 40.632 | 1.008 | 38.607.761 | ||||
| 2023-05-24 | 2023-05-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 24,8000 | 3.781 | 94 | 3.533.039 | ||||
| 2023-05-24 | 2023-05-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 24,4604 | 82.148 | 2.009 | 38.567.129 | ||||
| 2023-05-24 | 2023-05-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 24,4604 | 7.645 | 187 | 3.529.258 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Kihara James | ACAD | Common Stock | D | 22,5000 | -5.947 | -134 | 11.144 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Kihara James | ACAD | Common Stock | D | 5.947 | 17.091 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Kihara James | ACAD | Common Stock | D | 5.947 | 17.091 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 22,5000 | -15.310 | -344 | 21.905 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 14.869 | 37.215 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 14.869 | 37.215 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 22,5000 | -14.869 | -335 | 24.356 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 14.869 | 39.225 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Teehan Brendan | ACAD | Common Stock | D | 14.869 | 39.225 | ||||||
| 2023-05-02 | 2023-05-01 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 21,1800 | -917 | -19 | 25.513 | ||||
| 2023-05-02 | 2023-04-29 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 3.005 | 26.430 | ||||||
| 2023-05-02 | 2023-05-01 | 4 | Teehan Brendan | ACAD | Common Stock | D | 21,1800 | -548 | -12 | 9.487 | ||||
| 2023-05-02 | 2023-04-29 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.567 | 10.035 | ||||||
| 2023-05-02 | 2023-05-01 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 21,1800 | -7.806 | -165 | 108.297 | ||||
| 2023-05-02 | 2023-04-29 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15.625 | 116.103 | ||||||
| 2023-04-11 | 2023-04-10 | 4 | Kihara James | ACAD | Common Stock | D | 18,1400 | -523 | -9 | 5.197 | ||||
| 2023-04-11 | 2023-04-07 | 4 | Kihara James | ACAD | Common Stock | D | 1.489 | 5.720 | ||||||
| 2023-04-07 | 2023-04-06 | 4 | Teehan Brendan | ACAD | Common Stock | D | 18,1600 | -1.751 | -32 | 8.468 | ||||
| 2023-04-07 | 2023-04-05 | 4 | Teehan Brendan | ACAD | Common Stock | D | 5.024 | 10.219 | ||||||
| 2023-04-07 | 2023-04-06 | 4 | Kihara James | ACAD | Common Stock | D | 18,1600 | -701 | -13 | 4.231 | ||||
| 2023-04-07 | 2023-04-05 | 4 | Kihara James | ACAD | Common Stock | D | 2.009 | 4.932 | ||||||
| 2023-04-07 | 2023-04-06 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 18,1600 | -1.916 | -35 | 7.477 | ||||
| 2023-04-07 | 2023-04-05 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 5.275 | 9.393 | ||||||
| 2023-04-07 | 2023-04-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 18,1600 | -8.582 | -156 | 100.478 | ||||
| 2023-04-07 | 2023-04-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17.333 | 109.060 | ||||||
| 2023-04-07 | 2023-04-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 18,1600 | -1.456 | -26 | 23.425 | ||||
| 2023-04-07 | 2023-04-05 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 4.773 | 24.881 | ||||||
| 2023-02-27 | 2023-02-24 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 18,7800 | -3.851 | -72 | 91.727 | ||||
| 2023-02-27 | 2023-02-23 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 10.945 | 95.578 | ||||||
| 2023-02-27 | 2023-02-24 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 18,7800 | -577 | -11 | 4.118 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.353 | 4.695 | ||||||
| 2023-02-27 | 2023-02-24 | 4 | Teehan Brendan | ACAD | Common Stock | D | 18,7800 | -461 | -9 | 5.195 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.107 | 5.656 | ||||||
| 2023-02-27 | 2023-02-24 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 18,7800 | -803 | -15 | 20.108 | ||||
| 2023-02-27 | 2023-02-23 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 2.214 | 20.911 | ||||||
| 2023-02-27 | 2023-02-24 | 4 | Kihara James | ACAD | Common Stock | D | 18,7800 | -350 | -7 | 2.923 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Kihara James | ACAD | Common Stock | D | 840 | 3.273 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Brege Laura | ACAD | Common Stock | D | 18,2500 | -12.500 | -228 | 0 | ||||
| 2023-01-17 | 2023-01-12 | 4 | Brege Laura | ACAD | Common Stock | D | 17,0100 | 12.500 | 213 | 12.500 | ||||
| 2023-01-17 | 2023-01-12 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 5,2200 | 15.000 | 78 | 38.484.981 | ||||
| 2023-01-17 | 2023-01-12 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 5,2200 | 15.000 | 78 | 38.484.981 | ||||
| 2023-01-10 | 2023-01-09 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17,1303 | -3.904 | -67 | 84.633 | ||||
| 2023-01-10 | 2023-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 9.528 | 88.537 | ||||||
| 2023-01-10 | 2023-01-09 | 4 | Teehan Brendan | ACAD | Common Stock | D | 17,1303 | -532 | -9 | 4.549 | ||||
| 2023-01-10 | 2023-01-06 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.286 | 5.081 | ||||||
| 2023-01-10 | 2023-01-09 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 17,1303 | -589 | -10 | 18.697 | ||||
| 2023-01-10 | 2023-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 1.633 | 19.286 | ||||||
| 2022-11-22 | 2022-11-21 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 15,0700 | -1.847 | -28 | 61.234 | ||||
| 2022-11-22 | 2022-11-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 6.250 | 63.081 | ||||||
| 2022-10-18 | 2022-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 15,8100 | -1.326 | -21 | 56.831 | ||||
| 2022-10-18 | 2022-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 2.969 | 58.157 | ||||||
| 2022-10-18 | 2022-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15,8100 | -2.804 | -44 | 79.009 | ||||
| 2022-10-18 | 2022-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 5.938 | 81.813 | ||||||
| 2022-06-10 | 2022-06-09 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 17,9095 | -653 | -12 | 3.342 | ||||
| 2022-06-10 | 2022-06-08 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.893 | 3.995 | ||||||
| 2022-06-09 | 2022-06-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17.104 | 38.469.981 | ||||||
| 2022-06-09 | 2022-06-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17.104 | 38.469.981 | ||||||
| 2022-05-03 | 2022-05-02 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 18,1819 | -5.483 | -100 | 75.875 | ||||
| 2022-05-03 | 2022-04-29 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -15.625 | 15.625 | ||||||
| 2022-05-03 | 2022-04-29 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15.625 | 81.358 | ||||||
| 2022-05-03 | 2022-05-02 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 18,1818 | -2.865 | -52 | 55.188 | ||||
| 2022-05-03 | 2022-04-29 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -9.616 | 9.616 | ||||||
| 2022-05-03 | 2022-04-29 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 9.616 | 58.053 | ||||||
| 2022-05-03 | 2022-05-02 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 18,1820 | -894 | -16 | 16.742 | ||||
| 2022-05-03 | 2022-04-29 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | -3.005 | 3.005 | ||||||
| 2022-05-03 | 2022-04-29 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 3.005 | 17.636 | ||||||
| 2022-05-03 | 2022-05-02 | 4 | Teehan Brendan | ACAD | Common Stock | D | 18,1820 | -552 | -10 | 3.437 | ||||
| 2022-05-03 | 2022-04-29 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | -1.567 | 1.567 | ||||||
| 2022-05-03 | 2022-04-29 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.567 | 3.989 | ||||||
| 2022-04-11 | 2022-04-08 | 4 | Kihara James | ACAD | Common Stock | D | 27,0500 | -1.025 | -28 | 2.433 | ||||
| 2022-04-11 | 2022-04-07 | 4 | Kihara James | ACAD | Restricted Stock Units | D | -2.977 | 2.978 | ||||||
| 2022-04-11 | 2022-04-07 | 4 | Kihara James | ACAD | Common Stock | D | 2.977 | 3.458 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Kihara James | ACAD | Restricted Stock Units | D | 8.039 | 8.039 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Kihara James | ACAD | Stock Options (Right to Buy) | D | 25,75 | 13.793 | 13.793 | |||||
| 2022-04-07 | 2022-04-05 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | 20.096 | 20.096 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Teehan Brendan | ACAD | Stock Options (Right to Buy) | D | 25,75 | 68.966 | 68.966 | |||||
| 2022-04-07 | 2022-04-05 | 4 | Schneyer Mark C. | ACAD | Restricted Stock Units | D | 21.101 | 21.101 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Schneyer Mark C. | ACAD | Stock Options (Right to Buy) | D | 25,75 | 72.414 | 72.414 | |||||
| 2022-04-07 | 2022-04-05 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 96.463 | 96.463 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 19.092 | 19.092 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | KIM AUSTIN D. | ACAD | Stock Options (Right to Buy) | D | 25,75 | 65.517 | 65.517 | |||||
| 2022-04-07 | 2022-04-05 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 144.695 | 144.695 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 36.174 | 36.174 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | Stankovic Srdjan R. | ACAD | Stock Options (Right to Buy) | D | 25,75 | 124.138 | 124.138 | |||||
| 2022-04-07 | 2022-04-05 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 277.331 | 277.331 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 69.333 | 69.333 | ||||||
| 2022-04-07 | 2022-04-05 | 4 | DAVIS STEPHEN | ACAD | Stock Options (Right to Buy) | D | 25,75 | 237.931 | 237.931 | |||||
| 2022-02-25 | 2022-02-23 | 4 | Schneyer Mark C. | ACAD | Restricted Stock Units | D | 1.352 | 4.059 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 23,8000 | -553 | -13 | 2.102 | ||||
| 2022-02-25 | 2022-02-23 | 4 | Schneyer Mark C. | ACAD | Common Stock | D | 1.352 | 2.655 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 2.213 | 6.642 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 23,8000 | -782 | -19 | 14.631 | ||||
| 2022-02-25 | 2022-02-23 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 2.213 | 15.413 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | 1.106 | 3.321 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Teehan Brendan | ACAD | Common Stock | D | 23,8000 | -472 | -11 | 2.422 | ||||
| 2022-02-25 | 2022-02-23 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.106 | 2.894 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 10.945 | 32.837 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 23,8000 | -3.928 | -93 | 65.733 | ||||
| 2022-02-25 | 2022-02-23 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 10.945 | 69.661 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Kihara James | ACAD | Restricted Stock Units | D | 840 | 2.520 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Kihara James | ACAD | Common Stock | D | 23,8000 | -359 | -9 | 481 | ||||
| 2022-02-25 | 2022-02-23 | 4 | Kihara James | ACAD | Common Stock | D | 840 | 840 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 4.919 | 14.758 | ||||||
| 2022-02-25 | 2022-02-23 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 23,8000 | -1.501 | -36 | 48.437 | ||||
| 2022-02-25 | 2022-02-23 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 4.919 | 49.938 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -9.527 | 19.056 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 23,0500 | -3.718 | -86 | 58.716 | ||||
| 2022-01-10 | 2022-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 9.527 | 62.434 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | -1.633 | 3.267 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 23,0500 | -574 | -13 | 13.200 | ||||
| 2022-01-10 | 2022-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 1.633 | 13.774 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -5.444 | 10.889 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 23,0500 | -1.937 | -45 | 45.019 | ||||
| 2022-01-10 | 2022-01-06 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 5.444 | 46.956 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | -1.286 | 2.573 | ||||||
| 2022-01-10 | 2022-01-06 | 4 | Teehan Brendan | ACAD | Common Stock | D | 23,0500 | -538 | -12 | 1.788 | ||||
| 2022-01-10 | 2022-01-06 | 4 | Teehan Brendan | ACAD | Common Stock | D | 1.286 | 2.326 | ||||||
| 2021-12-20 | 3 | Schneyer Mark C. | ACAD | Common Stock | D | 1.303 | ||||||||
| 2021-11-23 | 2021-11-22 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,0100 | -2.803 | -53 | 41.512 | ||||
| 2021-11-23 | 2021-11-19 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -6.250 | 6.250 | ||||||
| 2021-11-23 | 2021-11-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 6.250 | 44.315 | ||||||
| 2021-11-19 | 2021-11-17 | 4 | Kihara James | ACAD | Restricted Stock Units | D | 15.860 | 15.860 | ||||||
| 2021-11-19 | 2021-11-17 | 4 | Kihara James | ACAD | Restricted Stock Units | D | 15.860 | 15.860 | ||||||
| 2021-11-19 | 2021-11-17 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | 39.651 | 39.651 | ||||||
| 2021-11-19 | 2021-11-17 | 4 | Teehan Brendan | ACAD | Restricted Stock Units | D | 39.651 | 39.651 | ||||||
| 2021-11-05 | 3 | Teehan Brendan | ACAD | Common Stock | D | 807 | ||||||||
| 2021-10-19 | 2021-10-18 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 17,4100 | -1.338 | -23 | 38.065 | ||||
| 2021-10-19 | 2021-10-15 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -2.969 | 2.969 | ||||||
| 2021-10-19 | 2021-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 2.969 | 39.403 | ||||||
| 2021-10-19 | 2021-10-18 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 17,4100 | -2.963 | -52 | 52.906 | ||||
| 2021-10-19 | 2021-10-15 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -5.938 | 5.938 | ||||||
| 2021-10-19 | 2021-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 5.938 | 55.869 | ||||||
| 2021-10-01 | 2021-09-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Restricted Stock Units | D | 1.918 | 1.919 | ||||||
| 2021-10-01 | 2021-09-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Common Stock | D | 1.918 | 1.918 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | SOLAND DANIEL B | ACAD | Restricted Stock Units | D | 6.391 | 6.391 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | SOLAND DANIEL B | ACAD | Director Stock Options (Right to Buy) | D | 24,88 | 11.637 | 11.637 | |||||
| 2021-06-24 | 2021-06-22 | 4 | GAROFALO ELIZABETH A. | ACAD | Restricted Stock Units | D | 6.391 | 6.391 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | GAROFALO ELIZABETH A. | ACAD | Director Stock Options (Right to Buy) | D | 24,88 | 11.637 | 11.637 | |||||
| 2021-06-24 | 2021-06-22 | 4 | HARRIGAN EDMUND | ACAD | Restricted Stock Units | D | 6.391 | 6.391 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | HARRIGAN EDMUND | ACAD | Director Stock Options (Right to Buy) | D | 24,88 | 11.637 | 11.637 | |||||
| 2021-06-24 | 2021-06-22 | 4 | Daly James M | ACAD | Restricted Stock Units | D | 6.391 | 6.391 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | Daly James M | ACAD | Director Stock Options (Right to Buy) | D | 24,88 | 11.637 | 11.637 | |||||
| 2021-06-24 | 2021-06-22 | 4 | Brege Laura | ACAD | Restricted Stock Units | D | 6.391 | 6.391 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | Brege Laura | ACAD | Director Stock Options (Right to Buy) | D | 24,88 | 11.637 | 11.637 | |||||
| 2021-06-24 | 2021-06-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Options (right to buy) | I | 24,88 | 23.274 | 23.274 | |||||
| 2021-06-24 | 2021-06-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 12.782 | 38.452.877 | ||||||
| 2021-06-24 | 2021-06-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 12.782 | 38.452.877 | ||||||
| 2021-04-30 | 2021-04-30 | 4 | Ridloff Elena | ACAD | Common Stock | D | 20,3300 | -1.032 | -21 | 10.553 | ||||
| 2021-04-30 | 2021-04-29 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | -3.245 | 6.491 | ||||||
| 2021-04-30 | 2021-04-29 | 4 | Ridloff Elena | ACAD | Common Stock | D | 3.245 | 11.585 | ||||||
| 2021-04-30 | 2021-04-30 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 20,3300 | -1.054 | -21 | 11.371 | ||||
| 2021-04-30 | 2021-04-29 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | -3.005 | 6.010 | ||||||
| 2021-04-30 | 2021-04-29 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 3.005 | 12.425 | ||||||
| 2021-04-30 | 2021-04-30 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 20,3300 | -7.850 | -160 | 49.312 | ||||
| 2021-04-30 | 2021-04-29 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -15.625 | 31.250 | ||||||
| 2021-04-30 | 2021-04-29 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15.625 | 57.162 | ||||||
| 2021-04-30 | 2021-04-30 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 20,3300 | -4.230 | -86 | 36.434 | ||||
| 2021-04-30 | 2021-04-29 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -9.615 | 19.232 | ||||||
| 2021-04-30 | 2021-04-29 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 9.615 | 40.664 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 19.677 | 19.677 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | Stankovic Srdjan R. | ACAD | Stock Options (Right to Buy) | D | 49,74 | 72.463 | 72.463 | |||||
| 2021-02-25 | 2021-02-23 | 4 | Kihara James | ACAD | Restricted Stock Units | D | 3.360 | 3.360 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | Kihara James | ACAD | Stock Options (Right to Buy) | D | 49,74 | 6.187 | 6.187 | |||||
| 2021-02-25 | 2021-02-23 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | 9.839 | 9.839 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | Ridloff Elena | ACAD | Stock Options (Right to Buy) | D | 49,74 | 36.231 | 36.231 | |||||
| 2021-02-25 | 2021-02-23 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 8.855 | 8.855 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | KIM AUSTIN D. | ACAD | Stock Options (Right to Buy) | D | 49,74 | 32.608 | 32.608 | |||||
| 2021-02-25 | 2021-02-23 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 43.782 | 43.782 | ||||||
| 2021-02-25 | 2021-02-23 | 4 | DAVIS STEPHEN | ACAD | Stock Options (Right to Buy) | D | 49,74 | 161.230 | 161.230 | |||||
| 2021-02-08 | 2021-02-04 | 4 | DAVIS STEPHEN | ACAD | Employee Stock Options (Right to Buy) | D | 21,28 | 23.750 | 23.750 | |||||
| 2021-02-08 | 2021-02-04 | 4 | DAVIS STEPHEN | ACAD | Employee Stock Options (Right to Buy) | D | 29,59 | 40.625 | 40.625 | |||||
| 2021-02-08 | 2021-02-04 | 4 | DAVIS STEPHEN | ACAD | Employee Stock Options (Right to Buy) | D | 35,80 | 40.625 | 40.625 | |||||
| 2021-02-08 | 2021-02-04 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 50,6100 | -14.195 | -718 | 28.900 | ||||
| 2021-02-08 | 2021-02-04 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 31.250 | 43.059 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | Ridloff Elena | ACAD | Common Stock | D | 50,6100 | -2.051 | -104 | 8.340 | ||||
| 2021-02-08 | 2021-02-04 | 4 | Ridloff Elena | ACAD | Common Stock | D | 6.490 | 10.391 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 21,28 | 11.875 | 11.875 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 35,80 | 21.875 | 21.875 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 29,59 | 15.625 | 15.625 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,6100 | -8.429 | -427 | 31.049 | ||||
| 2021-02-08 | 2021-02-04 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19.231 | 39.478 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 50,6100 | -2.107 | -107 | 9.911 | ||||
| 2021-02-08 | 2021-02-04 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 6.009 | 12.018 | ||||||
| 2021-01-14 | 2021-01-12 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (Right to Buy) | D | 18,12 | -700 | 89.562 | |||||
| 2021-01-14 | 2021-01-12 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 55,0100 | -700 | -39 | 20.247 | ||||
| 2021-01-14 | 2021-01-12 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 18,1200 | 700 | 13 | 20.947 | ||||
| 2021-01-08 | 2021-01-06 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | -2.722 | 8.167 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 53,3400 | -1.120 | -60 | 8.059 | ||||
| 2021-01-08 | 2021-01-06 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 2.722 | 9.179 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | -1.633 | 4.900 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 53,3400 | -678 | -36 | 5.518 | ||||
| 2021-01-08 | 2021-01-06 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 1.633 | 6.196 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | -1.016 | 9.873 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | Ridloff Elena | ACAD | Common Stock | D | 53,3400 | -1.016 | -54 | 3.901 | ||||
| 2021-01-08 | 2021-01-06 | 4 | Ridloff Elena | ACAD | Common Stock | D | 2.722 | 4.917 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -9.527 | 28.583 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 53,3400 | -3.484 | -186 | 24.482 | ||||
| 2021-01-08 | 2021-01-06 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 9.527 | 27.966 | ||||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (Right to Buy) | D | 18,12 | -3.488 | 90.262 | |||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (Right to Buy) | D | 21,28 | -12.864 | 22.761 | |||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (Right to Buy) | D | 35,80 | -13.381 | 56.250 | |||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 55,2192 | -29.733 | -1.642 | 20.247 | ||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 18,1200 | 3.488 | 63 | 49.980 | ||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 21,2800 | 12.864 | 274 | 46.492 | ||||
| 2021-01-08 | 2021-01-08 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 35,8000 | 13.381 | 479 | 33.628 | ||||
| 2021-01-08 | 2021-01-07 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 55,1159 | -61.619 | -3.396 | 20.247 | ||||
| 2021-01-08 | 2021-01-07 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 35,8000 | 61.619 | 2.206 | 81.866 | ||||
| 2021-01-08 | 2021-01-06 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (Right to Buy) | D | 35,80 | -61.619 | 69.631 | |||||
| 2021-01-08 | 2021-01-06 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -5.444 | 16.333 | ||||||
| 2021-01-08 | 2021-01-06 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 53,3400 | -1.725 | -92 | 20.247 | ||||
| 2021-01-08 | 2021-01-06 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 5.444 | 21.972 | ||||||
| 2020-11-20 | 2020-11-20 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 53,5000 | -2.728 | -146 | 16.528 | ||||
| 2020-11-20 | 2020-11-19 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -6.250 | 12.500 | ||||||
| 2020-11-20 | 2020-11-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 6.250 | 19.256 | ||||||
| 2020-10-29 | 2020-10-27 | 4 | KIM AUSTIN D. | ACAD | Stock Option (Right to Buy) | D | 17,58 | -8.750 | 113.750 | |||||
| 2020-10-29 | 2020-10-27 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 45,1013 | -8.750 | -395 | 3.851 | ||||
| 2020-10-29 | 2020-10-27 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 17,5800 | 8.750 | 154 | 12.601 | ||||
| 2020-10-19 | 2020-10-16 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 42,5600 | -1.247 | -53 | 6.457 | ||||
| 2020-10-19 | 2020-10-15 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | -2.500 | 5.000 | ||||||
| 2020-10-19 | 2020-10-15 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 2.500 | 7.704 | ||||||
| 2020-10-19 | 2020-10-16 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 42,5600 | -1.297 | -55 | 13.006 | ||||
| 2020-10-19 | 2020-10-15 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -2.969 | 5.938 | ||||||
| 2020-10-19 | 2020-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 2.969 | 14.303 | ||||||
| 2020-10-19 | 2020-10-16 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 42,5600 | -2.960 | -126 | 14.786 | ||||
| 2020-10-19 | 2020-10-15 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -5.937 | 11.876 | ||||||
| 2020-10-19 | 2020-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 5.937 | 17.746 | ||||||
| 2020-10-01 | 2020-09-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Restricted Stock Units | D | 3.837 | 3.837 | ||||||
| 2020-10-01 | 2020-09-29 | 4 | GAROFALO ELIZABETH A. | ACAD | Stock Option (Right to Buy) | D | 40,41 | 6.865 | 6.865 | |||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 25,12 | -14.750 | 44.292 | |||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 21,28 | -5.000 | 25.000 | |||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 19,98 | -7.500 | 570.000 | |||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 56,5382 | -11.100 | -628 | 5.204 | ||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 56,0503 | -16.150 | -905 | 16.304 | ||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 25,1200 | 14.750 | 371 | 32.454 | ||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 21,2800 | 5.000 | 106 | 17.704 | ||||
| 2020-07-09 | 2020-07-07 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 19,9800 | 7.500 | 150 | 12.704 | ||||
| 2020-06-25 | 2020-06-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Options (right to buy) | I | 52,73 | 11.158 | 11.158 | |||||
| 2020-06-25 | 2020-06-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 6.118 | 38.440.095 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 6.118 | 38.440.095 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | Brege Laura | ACAD | Restricted Stock Units | D | 3.059 | 3.059 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | Brege Laura | ACAD | Director Stock Options (Right to Buy) | D | 52,73 | 5.579 | 5.579 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Daly James M | ACAD | Restricted Stock Units | D | 3.059 | 3.059 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | Daly James M | ACAD | Director Stock Options (Right to Buy) | D | 52,73 | 5.579 | 5.579 | |||||
| 2020-06-25 | 2020-06-23 | 4 | HARRIGAN EDMUND | ACAD | Restricted Stock Units | D | 3.059 | 3.059 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | HARRIGAN EDMUND | ACAD | Director Stock Options (Right to Buy) | D | 52,73 | 5.579 | 5.579 | |||||
| 2020-06-25 | 2020-06-23 | 4 | SOLAND DANIEL B | ACAD | Restricted Stock Units | D | 3.059 | 3.059 | ||||||
| 2020-06-25 | 2020-06-23 | 4 | SOLAND DANIEL B | ACAD | Director Stock Options (Right to Buy) | D | 52,73 | 5.579 | 5.579 | |||||
| 2020-06-19 | 2020-06-19 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 18,12 | -16.452 | 93.750 | |||||
| 2020-06-19 | 2020-06-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,1164 | -16.452 | -825 | 11.334 | ||||
| 2020-06-19 | 2020-06-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 18,1200 | 16.452 | 298 | 27.786 | ||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 18,12 | -39.798 | 110.202 | |||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,98 | -17.494 | 34.112 | |||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,65 | -8.551 | 0 | |||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,0088 | -65.843 | -3.293 | 11.334 | ||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 18,1200 | 39.798 | 721 | 77.177 | ||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,9800 | 17.494 | 350 | 37.379 | ||||
| 2020-06-19 | 2020-06-18 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,6500 | 8.551 | 168 | 19.885 | ||||
| 2020-05-15 | 2020-05-14 | 4 | DAVIS STEPHEN | ACAD | Stock Option (Right to Buy) | D | 19,65 | -88.542 | 100.000 | |||||
| 2020-05-15 | 2020-05-14 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 45,0148 | -4.321 | -195 | 11.809 | ||||
| 2020-05-15 | 2020-05-14 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 45,6489 | -84.221 | -3.845 | 16.130 | ||||
| 2020-05-15 | 2020-05-14 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 19,6500 | 88.542 | 1.740 | 100.351 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Stock Option (Right to Buy) | D | 19,65 | -111.458 | 188.542 | |||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 45,1173 | -8.197 | -370 | 11.809 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 45,7133 | -63.392 | -2.898 | 20.006 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 46,4302 | -20.756 | -964 | 83.398 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 48,5981 | -5.205 | -253 | 104.154 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 48,9822 | -13.908 | -681 | 109.359 | ||||
| 2020-05-15 | 2020-05-13 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 19,6500 | 111.458 | 2.190 | 123.267 | ||||
| 2020-05-13 | 2020-05-11 | 4 | Daly James M | ACAD | Stock Option (Right to Buy) | D | 27,25 | -15.000 | 0 | |||||
| 2020-05-13 | 2020-05-11 | 4 | Daly James M | ACAD | Stock Option (Right to Buy) | D | 25,24 | -11.250 | 11.250 | |||||
| 2020-05-13 | 2020-05-11 | 4 | Daly James M | ACAD | Common Stock | D | 51,1306 | -26.250 | -1.342 | 0 | ||||
| 2020-05-13 | 2020-05-11 | 4 | Daly James M | ACAD | Common Stock | D | 27,2500 | 15.000 | 409 | 26.250 | ||||
| 2020-05-13 | 2020-05-11 | 4 | Daly James M | ACAD | Common Stock | D | 25,2400 | 11.250 | 284 | 11.250 | ||||
| 2020-05-01 | 2020-04-30 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 49,2100 | -4.308 | -212 | 11.334 | ||||
| 2020-05-01 | 2020-04-29 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -9.615 | 28.847 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 9.615 | 15.642 | ||||||
| 2020-05-01 | 2020-04-30 | 4 | Ridloff Elena | ACAD | Common Stock | D | 49,2200 | -1.050 | -52 | 2.195 | ||||
| 2020-05-01 | 2020-04-29 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | -3.245 | 9.736 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | Ridloff Elena | ACAD | Stock Option (Right to Buy) | D | 25,12 | -10.000 | 35.547 | |||||
| 2020-05-01 | 2020-04-29 | 4 | Ridloff Elena | ACAD | Common Stock | D | 3.245 | 3.245 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | Ridloff Elena | ACAD | Common Stock | D | 50,7353 | -10.000 | -507 | 0 | ||||
| 2020-05-01 | 2020-04-29 | 4 | Ridloff Elena | ACAD | Common Stock | D | 25,1200 | 10.000 | 251 | 10.000 | ||||
| 2020-05-01 | 2020-04-30 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 49,2100 | -6.770 | -333 | 11.809 | ||||
| 2020-05-01 | 2020-04-29 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -15.625 | 46.875 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 15.625 | 18.579 | ||||||
| 2020-05-01 | 2020-04-30 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 49,2100 | -1.501 | -74 | 5.204 | ||||
| 2020-05-01 | 2020-04-29 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | -4.206 | 12.621 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 4.206 | 6.705 | ||||||
| 2020-05-01 | 2020-04-30 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 49,2200 | -1.072 | -53 | 2.441 | ||||
| 2020-05-01 | 2020-04-29 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | -3.004 | 9.015 | ||||||
| 2020-05-01 | 2020-04-29 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 3.004 | 3.513 | ||||||
| 2020-04-24 | 2020-04-23 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 21,28 | -11.875 | 35.625 | |||||
| 2020-04-24 | 2020-04-23 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,65 | -7.074 | 8.551 | |||||
| 2020-04-24 | 2020-04-23 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,0675 | -18.949 | -949 | 6.027 | ||||
| 2020-04-24 | 2020-04-23 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 21,2800 | 11.875 | 253 | 24.976 | ||||
| 2020-04-24 | 2020-04-23 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,6500 | 7.074 | 139 | 13.101 | ||||
| 2020-04-22 | 2020-04-22 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,98 | -19.644 | 51.606 | |||||
| 2020-04-22 | 2020-04-22 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,65 | -34.375 | 15.625 | |||||
| 2020-04-22 | 2020-04-22 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,0177 | -54.019 | -2.702 | 6.027 | ||||
| 2020-04-22 | 2020-04-22 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,9800 | 19.644 | 392 | 60.046 | ||||
| 2020-04-22 | 2020-04-22 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,6500 | 34.375 | 675 | 40.402 | ||||
| 2020-04-22 | 2020-04-20 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Option (Right to Buy) | D | 19,65 | -100.000 | 50.000 | |||||
| 2020-04-22 | 2020-04-20 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 50,1545 | -100.000 | -5.015 | 6.027 | ||||
| 2020-04-22 | 2020-04-20 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 19,6500 | 100.000 | 1.965 | 106.027 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 34,4665 | 42.473 | 1.464 | 38.433.977 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 34,4665 | 3.837 | 132 | 3.470.609 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,6321 | 33.464 | 1.125 | 38.391.504 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,6321 | 3.023 | 102 | 3.466.772 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,8498 | 2.201 | 72 | 38.358.040 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,8498 | 199 | 7 | 3.463.749 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,6072 | 46.225 | 1.507 | 38.355.839 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,6072 | 4.175 | 136 | 3.463.550 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,9350 | 275 | 9 | 38.309.614 | ||||
| 2020-03-18 | 2020-03-18 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,9350 | 25 | 1 | 3.459.375 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,8624 | 93.006 | 3.149 | 38.309.339 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,8624 | 8.402 | 285 | 3.459.350 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,3194 | 24.223 | 783 | 38.216.333 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,3194 | 2.188 | 71 | 3.450.948 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,1908 | 29.624 | 954 | 38.192.110 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 32,1908 | 2.676 | 86 | 3.448.760 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,8300 | 7.612 | 242 | 38.162.486 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,8300 | 688 | 22 | 3.446.084 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,7356 | 43.212 | 1.371 | 38.154.874 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,7356 | 3.903 | 124 | 3.445.396 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 30,9955 | 3.913 | 121 | 38.111.662 | ||||
| 2020-03-18 | 2020-03-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 30,9955 | 353 | 11 | 3.441.493 | ||||
| 2020-03-18 | 2020-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,5136 | 631.281 | 19.894 | 38.107.749 | ||||
| 2020-03-18 | 2020-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,5136 | 57.022 | 1.797 | 3.441.140 | ||||
| 2020-03-18 | 2020-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,1853 | 5.503 | 172 | 37.476.468 | ||||
| 2020-03-18 | 2020-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 31,1853 | 497 | 15 | 3.384.118 | ||||
| 2020-01-08 | 2020-01-06 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 38.110 | 38.110 | ||||||
| 2020-01-08 | 2020-01-06 | 4 | DAVIS STEPHEN | ACAD | Stock Options (Right to Buy) | D | 42,81 | 138.304 | 138.304 | |||||
| 2020-01-08 | 2020-01-06 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 21.777 | 21.777 | ||||||
| 2020-01-08 | 2020-01-06 | 4 | Stankovic Srdjan R. | ACAD | Stock Options (Right to Buy) | D | 42,81 | 79.031 | 79.031 | |||||
| 2020-01-08 | 2020-01-06 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 6.533 | 6.533 | ||||||
| 2020-01-08 | 2020-01-06 | 4 | KIM AUSTIN D. | ACAD | Stock Options (Right to Buy) | D | 42,81 | 23.709 | 23.709 | |||||
| 2020-01-08 | 2020-01-06 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | 10.889 | 10.889 | ||||||
| 2020-01-08 | 2020-01-06 | 4 | Ridloff Elena | ACAD | Stock Options (Right to Buy) | D | 42,81 | 39.516 | 39.516 | |||||
| 2020-01-08 | 2020-01-06 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | 10.889 | 10.889 | ||||||
| 2020-01-08 | 2020-01-06 | 4 | YANG MICHAEL J. | ACAD | Stock Options (Right to Buy) | D | 42,81 | 39.516 | 39.516 | |||||
| 2020-01-08 | 2020-01-07 | 4 | Brege Laura | ACAD | Stock Option (Right to Buy) | D | 1,75 | -10.000 | 0 | |||||
| 2020-01-08 | 2020-01-07 | 4 | Brege Laura | ACAD | Common Stock | D | 42,1900 | -10.000 | -422 | 0 | ||||
| 2020-01-08 | 2020-01-07 | 4 | Brege Laura | ACAD | Common Stock | D | 1,7500 | 10.000 | 18 | 10.000 | ||||
| 2019-12-13 | 2019-12-11 | 4 | KIM AUSTIN D. | ACAD | Stock Option (Right to Buy) | D | 17,58 | -17.500 | 122.500 | |||||
| 2019-12-13 | 2019-12-11 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 45,0615 | -17.500 | -789 | 509 | ||||
| 2019-12-13 | 2019-12-11 | 4 | KIM AUSTIN D. | ACAD | Common Stock | D | 17,5800 | 17.500 | 308 | 18.009 | ||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 35,86 | -72.979 | 312.500 | |||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 21,28 | -10.000 | 30.000 | |||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 19,98 | -22.500 | 577.500 | |||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 43,7350 | -5.032 | -220 | 2.499 | ||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 44,4930 | -100.447 | -4.469 | 7.531 | ||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 35,8600 | 72.979 | 2.617 | 107.978 | ||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 21,2800 | 10.000 | 213 | 34.999 | ||||
| 2019-12-13 | 2019-12-12 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 19,9800 | 22.500 | 450 | 24.999 | ||||
| 2019-12-11 | 2019-12-09 | 4 | Ridloff Elena | ACAD | Stock Option (Right to Buy) | D | 15,81 | -36.000 | 64.000 | |||||
| 2019-12-11 | 2019-12-09 | 4 | Ridloff Elena | ACAD | Common Stock | D | 49,0940 | -19.478 | -956 | 0 | ||||
| 2019-12-11 | 2019-12-09 | 4 | Ridloff Elena | ACAD | Common Stock | D | 49,8080 | -5.502 | -274 | 19.478 | ||||
| 2019-12-11 | 2019-12-09 | 4 | Ridloff Elena | ACAD | Common Stock | D | 50,5950 | -11.020 | -558 | 24.980 | ||||
| 2019-12-11 | 2019-12-09 | 4 | Ridloff Elena | ACAD | Common Stock | D | 15,8100 | 36.000 | 569 | 36.000 | ||||
| 2019-12-11 | 2019-12-09 | 4 | YANG MICHAEL J. | ACAD | Stock Option (Right to Buy) | D | 35,86 | -14.521 | 385.479 | |||||
| 2019-12-11 | 2019-12-09 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 50,0531 | -3.502 | -175 | 1.623 | ||||
| 2019-12-11 | 2019-12-09 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 50,5950 | -11.019 | -558 | 5.125 | ||||
| 2019-12-11 | 2019-12-09 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 35,8600 | 14.521 | 521 | 16.144 | ||||
| 2019-12-06 | 2019-12-05 | 4 | DAVIS STEPHEN | ACAD | Stock Option (Right to Buy) | D | 19,65 | -150.000 | 300.000 | |||||
| 2019-12-06 | 2019-12-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 51,3200 | -28.256 | -1.450 | 2.954 | ||||
| 2019-12-06 | 2019-12-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 52,0900 | -40.159 | -2.092 | 31.210 | ||||
| 2019-12-06 | 2019-12-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 52,8200 | -81.585 | -4.309 | 71.369 | ||||
| 2019-12-06 | 2019-12-05 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 19,6500 | 150.000 | 2.948 | 152.954 | ||||
| 2019-11-21 | 2019-11-19 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -6.250 | 18.750 | ||||||
| 2019-11-21 | 2019-11-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 46,4100 | -2.160 | -100 | 6.027 | ||||
| 2019-11-21 | 2019-11-19 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 6.250 | 8.187 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | -5.937 | 17.813 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 39,6500 | -2.983 | -118 | 2.954 | ||||
| 2019-10-17 | 2019-10-15 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 5.937 | 5.937 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | -2.968 | 8.907 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 39,6500 | -1.031 | -41 | 1.937 | ||||
| 2019-10-17 | 2019-10-15 | 4 | Stankovic Srdjan R. | ACAD | Common Stock | D | 2.968 | 2.968 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | -2.500 | 7.500 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 39,6500 | -877 | -35 | 1.623 | ||||
| 2019-10-17 | 2019-10-15 | 4 | YANG MICHAEL J. | ACAD | Common Stock | D | 2.500 | 2.500 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | Miller Eric Alejandro | ACAD | Restricted Stock Units | D | -417 | 1.254 | ||||||
| 2019-10-17 | 2019-10-15 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 39,6500 | -147 | -6 | 270 | ||||
| 2019-10-17 | 2019-10-15 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 417 | 417 | ||||||
| 2019-10-11 | 2019-10-10 | 4 | DAVIS STEPHEN | ACAD | Stock Option (Right to Buy) | D | 19,65 | -120.208 | 450.000 | |||||
| 2019-10-11 | 2019-10-10 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 40,1890 | -120.208 | -4.831 | 0 | ||||
| 2019-10-11 | 2019-10-10 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 19,6500 | 120.208 | 2.362 | 120.208 | ||||
| 2019-10-11 | 2019-10-09 | 4 | DAVIS STEPHEN | ACAD | Stock Option (Right to Buy) | D | 19,65 | -29.792 | 570.208 | |||||
| 2019-10-11 | 2019-10-09 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 40,0010 | -29.792 | -1.192 | 0 | ||||
| 2019-10-11 | 2019-10-09 | 4 | DAVIS STEPHEN | ACAD | Common Stock | D | 19,6500 | 29.792 | 585 | 29.792 | ||||
| 2019-09-20 | 2019-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 40,0000 | 1.494.025 | 59.761 | 37.470.965 | ||||
| 2019-09-20 | 2019-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 40,0000 | 68.475 | 2.739 | 3.383.621 | ||||
| 2019-09-11 | 2019-09-11 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 41,1800 | -4.645 | -191 | 0 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 16,50 | -1.972 | 3.598 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 35,80 | -4.593 | 4.594 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 36,54 | -4.439 | 2.911 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 29,24 | -6.063 | 552 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 32,28 | -3.900 | 0 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Stock Option (Right to Buy) | D | 20,65 | -7.500 | 0 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 39,4900 | -28.467 | -1.124 | 4.645 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 16,5000 | 1.972 | 33 | 33.112 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 35,8000 | 4.593 | 164 | 31.140 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 36,5400 | 4.439 | 162 | 26.547 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 29,2400 | 6.063 | 177 | 22.108 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 32,2800 | 3.900 | 126 | 16.045 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Miller Eric Alejandro | ACAD | Common Stock | D | 20,6500 | 7.500 | 155 | 12.145 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Daly James M | ACAD | Stock Option (Right to Buy) | D | 17,52 | -30.000 | 0 | |||||
| 2019-09-11 | 2019-09-09 | 4 | Daly James M | ACAD | Common Stock | D | 38,3900 | -400 | -15 | 0 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Daly James M | ACAD | Common Stock | D | 37,7873 | -29.600 | -1.119 | 400 | ||||
| 2019-09-11 | 2019-09-09 | 4 | Daly James M | ACAD | Common Stock | D | 17,5200 | 30.000 | 526 | 30.000 | ||||
| 2019-06-28 | 2019-06-26 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (Right to Buy) | D | 25,24 | -22.500 | 22.500 | |||||
| 2019-06-28 | 2019-06-26 | 4 | Daly James M | ACAD | Stock Option (Right to Buy) | D | 25,24 | -22.500 | 22.500 | |||||
| 2019-06-28 | 2019-06-26 | 4 | SOLAND DANIEL B | ACAD | Stock Option (Right to Buy) | D | 25,24 | -22.500 | 22.500 | |||||
| 2019-06-28 | 2019-06-26 | 4 | Brege Laura | ACAD | Stock Option (Right to Buy) | D | 25,24 | -15.000 | 15.000 | |||||
| 2019-06-28 | 2019-06-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Option (right to buy) | I | 25,24 | 30.000 | 30.000 | |||||
| 2019-06-07 | 2019-06-06 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock | D | 31.229 | 102.876 | ||||||
| 2019-06-07 | 2019-06-06 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock | D | 31.229 | 102.876 | ||||||
| 2019-06-07 | 2019-06-06 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | -421.756 | 3.315.146 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 62.500 | 62.500 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | DAVIS STEPHEN | ACAD | Stock Options (Right to Buy) | D | 25,12 | 219.298 | 219.298 | |||||
| 2019-05-01 | 2019-04-29 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 38.462 | 38.462 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | Stankovic Srdjan R. | ACAD | Stock Options (Right to Buy) | D | 25,12 | 134.953 | 134.953 | |||||
| 2019-05-01 | 2019-04-29 | 4 | KIM AUSTIN D. | ACAD | Restricted Stock Units | D | 12.019 | 12.019 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | KIM AUSTIN D. | ACAD | Stock Options (Right to Buy) | D | 25,12 | 42.173 | 42.173 | |||||
| 2019-05-01 | 2019-04-29 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | 12.981 | 12.981 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | Ridloff Elena | ACAD | Stock Options (Right to Buy) | D | 25,12 | 45.547 | 45.547 | |||||
| 2019-05-01 | 2019-04-29 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | 16.827 | 16.827 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | YANG MICHAEL J. | ACAD | Stock Options (Right to Buy) | D | 25,12 | 59.042 | 59.042 | |||||
| 2019-05-01 | 2019-04-29 | 4 | Miller Eric Alejandro | ACAD | Restricted Stock Units | D | 3.442 | 3.442 | ||||||
| 2019-05-01 | 2019-04-29 | 4 | Miller Eric Alejandro | ACAD | Stock Options (Right to Buy) | D | 25,12 | 6.039 | 6.039 | |||||
| 2019-04-02 | 2019-04-01 | 4 | Ridloff Elena | ACAD | Restricted Stock Units | D | 40.000 | 40.000 | ||||||
| 2019-01-11 | 2019-01-09 | 4 | Brege Laura | ACAD | Stock Option (Right to Buy) | D | 2,16 | -10.000 | 0 | |||||
| 2019-01-11 | 2019-01-09 | 4 | Brege Laura | ACAD | Common Stock | D | 20,0041 | -10.000 | -200 | 0 | ||||
| 2019-01-11 | 2019-01-09 | 4 | Brege Laura | ACAD | Common Stock | D | 2,1600 | 10.000 | 22 | 10.000 | ||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock Warrant (right to buy) | D | 0,01 | 1.569 | 1.569 | |||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock Warrant (right to buy) | D | 0,01 | 1.569 | 1.569 | |||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock Warrant (right to buy) | I | 0,01 | -10.731 | 0 | |||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock | D | 71.647 | 71.647 | ||||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP | ACAD | Common Stock | D | 71.647 | 71.647 | ||||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | -489.977 | 0 | ||||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17,0000 | 11.178.823 | 190.040 | 35.976.940 | ||||
| 2018-12-04 | 2018-11-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 17,0000 | 585.882 | 9.960 | 3.736.902 | ||||
| 2018-11-20 | 2018-11-19 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 25.000 | 25.000 | ||||||
| 2018-11-20 | 2018-11-19 | 4 | Stankovic Srdjan R. | ACAD | Employee Stock Options (Right to Buy) | D | 18,12 | 150.000 | 150.000 | |||||
| 2018-11-09 | 3 | Miller Eric Alejandro | ACAD | Common Stock | D | 6.424 | ||||||||
| 2018-11-09 | 3 | Miller Eric Alejandro | ACAD | Common Stock | D | 6.424 | ||||||||
| 2018-11-09 | 3 | Miller Eric Alejandro | ACAD | Common Stock | D | 6.424 | ||||||||
| 2018-10-24 | 2018-10-15 | 4 | DAVIS STEPHEN | ACAD | Restricted Stock Units | D | 23.750 | 23.750 | ||||||
| 2018-10-24 | 2018-10-15 | 4 | DAVIS STEPHEN | ACAD | Stock Option(right to buy) | D | 21,28 | 95.000 | 95.000 | |||||
| 2018-10-24 | 2018-10-15 | 4 | Stankovic Srdjan R. | ACAD | Restricted Stock Units | D | 11.875 | 11.875 | ||||||
| 2018-10-24 | 2018-10-15 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 21,28 | 47.500 | 47.500 | |||||
| 2018-10-24 | 2018-10-15 | 4 | YANG MICHAEL J. | ACAD | Restricted Stock Units | D | 10.000 | 10.000 | ||||||
| 2018-10-24 | 2018-10-15 | 4 | YANG MICHAEL J. | ACAD | Stock Option (right to buy) | D | 21,28 | 40.000 | 40.000 | |||||
| 2018-10-24 | 2018-10-15 | 4 | YOUNG TODD S. | ACAD | Restricted Stock Units | D | 4.688 | 4.688 | ||||||
| 2018-10-24 | 2018-10-15 | 4 | YOUNG TODD S. | ACAD | Stock Option (right to buy) | D | 21,28 | 18.750 | 18.750 | |||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 19,0924 | 131.007 | 2.501 | 24.798.117 | ||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 19,0924 | 14.555 | 278 | 3.151.020 | ||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 19,0110 | 38.207 | 726 | 24.667.110 | ||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 19,0110 | 4.245 | 81 | 3.136.465 | ||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 18,6366 | 920.495 | 17.155 | 24.628.903 | ||||
| 2018-09-24 | 2018-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 18,6366 | 102.267 | 1.906 | 3.132.220 | ||||
| 2018-07-20 | 2018-07-18 | 4 | KIM AUSTIN D. | ACAD | Stock Option (right to buy) | D | 17,58 | 140.000 | 140.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 17,52 | 15.000 | 15.000 | |||||
| 2018-06-08 | 2018-06-06 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Option (right to buy) | I | 17,52 | 30.000 | 30.000 | |||||
| 2018-04-20 | 2018-04-18 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 19,98 | 28.125 | 28.125 | |||||
| 2018-04-20 | 2018-04-18 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 19,98 | 135.000 | 135.000 | |||||
| 2018-04-20 | 2018-04-18 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 19,98 | 71.250 | 71.250 | |||||
| 2018-04-20 | 2018-04-18 | 4 | YANG MICHAEL J. | ACAD | Stock Option (right to buy) | D | 19,98 | 60.000 | 60.000 | |||||
| 2018-04-20 | 2018-04-18 | 4 | YOUNG TODD S. | ACAD | Stock Option (right to buy) | D | 19,98 | 28.125 | 28.125 | |||||
| 2018-03-02 | 2018-03-02 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 22,5200 | 3.000 | 68 | 10.000 | ||||
| 2018-03-02 | 2018-03-01 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 24,5200 | 2.000 | 49 | 7.000 | ||||
| 2018-03-02 | 2018-03-01 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 24,0900 | 3.000 | 72 | 5.000 | ||||
| 2018-03-02 | 2018-03-01 | 4 | SOLAND DANIEL B | ACAD | Common Stock | D | 23,0200 | 2.000 | 46 | 2.000 | ||||
| 2018-01-31 | 2018-01-29 | 4 | Baity Glenn | ACAD | Common Stock | D | 32,3884 | -36.558 | -1.184 | 83.734 | ||||
| 2018-01-11 | 2018-01-10 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,18 | -50.179 | 0 | |||||
| 2018-01-11 | 2018-01-10 | 4 | Baity Glenn | ACAD | Common Stock | D | 2,1800 | 50.179 | 109 | 120.292 | ||||
| 2018-01-04 | 2018-01-02 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 8,49 | -10.000 | 0 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 8,06 | -15.000 | 0 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Brege Laura | ACAD | Common Stock | D | 30,0617 | -25.000 | -752 | 0 | ||||
| 2018-01-04 | 2018-01-02 | 4 | Brege Laura | ACAD | Common Stock | D | 8,4900 | 10.000 | 85 | 25.000 | ||||
| 2018-01-04 | 2018-01-02 | 4 | Brege Laura | ACAD | Common Stock | D | 8,0600 | 15.000 | 121 | 15.000 | ||||
| 2018-01-04 | 2018-01-02 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,18 | -74.321 | 0 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,1414 | -74.321 | -2.240 | 70.113 | ||||
| 2018-01-04 | 2018-01-02 | 4 | Baity Glenn | ACAD | Common Stock | D | 2,1800 | 74.321 | 162 | 144.434 | ||||
| 2017-11-29 | 2017-11-27 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock Warrant (right to buy) | I | 1,38 | -39.378 | 0 | |||||
| 2017-11-29 | 2017-11-27 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,0000 | -1.941 | -54 | 489.977 | ||||
| 2017-11-29 | 2017-11-27 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 1,3800 | 39.378 | 54 | 491.918 | ||||
| 2017-10-16 | 2017-10-13 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock Warrant (right to buy) | I | 1,38 | -1.426.590 | 0 | |||||
| 2017-10-16 | 2017-10-13 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 35,4000 | -55.457 | -1.963 | 23.708.408 | ||||
| 2017-10-16 | 2017-10-13 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 1,3800 | 1.426.590 | 1.969 | 23.763.865 | ||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,00 | -20.000 | 0 | |||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -7.500 | 0 | |||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,18 | -1.000 | 124.500 | |||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Common Stock | D | 40,9078 | -37.500 | -1.534 | 69.656 | ||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Common Stock | D | 2,0000 | 20.000 | 40 | 107.156 | ||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 7.500 | 12 | 99.656 | ||||
| 2017-10-06 | 2017-10-05 | 4 | Baity Glenn | ACAD | Common Stock | D | 2,1800 | 1.000 | 2 | 79.656 | ||||
| 2017-10-06 | 2017-10-04 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,18 | -4.500 | 125.500 | |||||
| 2017-10-06 | 2017-10-04 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -6.500 | 7.500 | |||||
| 2017-10-06 | 2017-10-04 | 4 | Baity Glenn | ACAD | Common Stock | D | 2,1800 | 4.500 | 10 | 78.656 | ||||
| 2017-10-06 | 2017-10-04 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 6.500 | 11 | 74.156 | ||||
| 2017-09-08 | 2017-09-07 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 35,80 | 131.250 | 131.250 | |||||
| 2017-09-08 | 2017-09-07 | 4 | YANG MICHAEL J. | ACAD | Stock Option (right to buy) | D | 35,80 | 93.750 | 93.750 | |||||
| 2017-09-08 | 2017-09-07 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 35,80 | 46.875 | 46.875 | |||||
| 2017-09-08 | 2017-09-07 | 4 | YOUNG TODD S. | ACAD | Stock Option (right to buy) | D | 35,80 | 56.250 | 56.250 | |||||
| 2017-09-08 | 2017-09-07 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 35,80 | 243.750 | 243.750 | |||||
| 2017-09-01 | 2017-08-30 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -16.507 | 14.000 | |||||
| 2017-09-01 | 2017-08-30 | 4 | Baity Glenn | ACAD | Common Stock | D | 34,8706 | -26.507 | -924 | 67.656 | ||||
| 2017-09-01 | 2017-08-30 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 16.507 | 27 | 94.163 | ||||
| 2017-08-11 | 2017-08-09 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -13.400 | 30.507 | |||||
| 2017-08-11 | 2017-08-09 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -922 | 0 | |||||
| 2017-08-11 | 2017-08-09 | 4 | Baity Glenn | ACAD | Common Stock | D | 34,8788 | -14.322 | -500 | 77.656 | ||||
| 2017-08-11 | 2017-08-09 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 13.400 | 22 | 91.978 | ||||
| 2017-08-11 | 2017-08-09 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 922 | 1 | 78.578 | ||||
| 2017-08-08 | 2017-08-04 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -6.500 | 43.907 | |||||
| 2017-08-08 | 2017-08-04 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 6.500 | 11 | 77.656 | ||||
| 2017-07-21 | 2017-07-20 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -28.097 | 28.000 | |||||
| 2017-07-21 | 2017-07-20 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,0000 | -38.097 | -1.143 | 71.156 | ||||
| 2017-07-21 | 2017-07-20 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 28.097 | 46 | 109.253 | ||||
| 2017-07-19 | 2017-07-17 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 28,85 | 15.000 | 15.000 | |||||
| 2017-07-19 | 2017-07-17 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 28,85 | 15.000 | 15.000 | |||||
| 2017-07-19 | 2017-07-17 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 28,85 | 15.000 | 15.000 | |||||
| 2017-06-26 | 2017-06-22 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -1.903 | 56.097 | |||||
| 2017-06-26 | 2017-06-22 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,0004 | -1.903 | -57 | 81.156 | ||||
| 2017-06-26 | 2017-06-22 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 1.903 | 3 | 83.059 | ||||
| 2017-06-14 | 2017-06-13 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 27,25 | 15.000 | 15.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | Brege Laura | ACAD | Stock Option (right to buy) | D | 27,25 | 15.000 | 15.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 27,25 | 15.000 | 15.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 27,25 | 15.000 | 15.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Option (right to buy) | I | 27,25 | 30.000 | 30.000 | |||||
| 2017-05-17 | 2017-05-15 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -14.093 | 58.000 | |||||
| 2017-05-17 | 2017-05-15 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 14.093 | 23 | 81.156 | ||||
| 2017-03-31 | 2017-03-29 | 4 | YANG MICHAEL J. | ACAD | Stock Option (right to buy) | D | 35,86 | 400.000 | 400.000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 36,54 | 33.750 | 33.750 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 36,54 | 93.750 | 93.750 | |||||
| 2017-03-10 | 2017-03-08 | 4 | YOUNG TODD S. | ACAD | Stock Option (right to buy) | D | 36,54 | 37.500 | 37.500 | |||||
| 2017-03-10 | 2017-03-08 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 36,54 | 243.750 | 243.750 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 36,54 | 46.875 | 46.875 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 34,45 | -7.856 | 82.500 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Moore Terrence O | ACAD | Common Stock | D | 39,6500 | -7.856 | -311 | 1.671 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Moore Terrence O | ACAD | Common Stock | D | 34,4500 | 7.856 | 271 | 9.527 | ||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,64 | -6.365 | 0 | |||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 8,32 | -3.224 | 0 | |||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 8,32 | -16.776 | 0 | |||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Common Stock | D | 39,6555 | -26.365 | -1.046 | 67.063 | ||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6400 | 6.365 | 10 | 93.428 | ||||
| 2017-02-16 | 2017-02-14 | 4 | Baity Glenn | ACAD | Common Stock | D | 8,3200 | 20.000 | 166 | 87.063 | ||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 34,35 | -29.644 | 90.356 | |||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 27,20 | -19.687 | 13.125 | |||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,61 | -17.421 | 36.102 | |||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Common Stock | D | 39,8807 | -66.752 | -2.662 | 1.671 | ||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Common Stock | D | 34,4500 | 29.644 | 1.021 | 68.423 | ||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Common Stock | D | 27,2000 | 19.687 | 535 | 38.779 | ||||
| 2017-02-16 | 2017-02-16 | 4 | Moore Terrence O | ACAD | Common Stock | D | 19,6100 | 17.421 | 342 | 19.092 | ||||
| 2017-02-16 | 2017-02-15 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,61 | -1.700 | 53.523 | |||||
| 2017-02-16 | 2017-02-15 | 4 | Moore Terrence O | ACAD | Common Stock | D | 39,6500 | -1.700 | -67 | 1.671 | ||||
| 2017-02-16 | 2017-02-15 | 4 | Moore Terrence O | ACAD | Common Stock | D | 19,6100 | 1.700 | 33 | 3.371 | ||||
| 2017-02-16 | 2017-02-14 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,61 | -74.381 | 55.223 | |||||
| 2017-02-16 | 2017-02-14 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,61 | -12.747 | 7.649 | |||||
| 2017-02-16 | 2017-02-14 | 4 | Moore Terrence O | ACAD | Common Stock | D | 39,6863 | -89.088 | -3.536 | 1.671 | ||||
| 2017-02-16 | 2017-02-14 | 4 | Moore Terrence O | ACAD | Common Stock | D | 19,6100 | 87.128 | 1.709 | 90.759 | ||||
| 2017-02-03 | 2017-02-01 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -21.078 | 0 | |||||
| 2017-02-03 | 2017-02-01 | 4 | Baity Glenn | ACAD | Common Stock | D | 35,1497 | -31.078 | -1.092 | 67.063 | ||||
| 2017-02-03 | 2017-02-01 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 21.078 | 33 | 98.141 | ||||
| 2016-12-29 | 2016-12-28 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -5.500 | 72.093 | |||||
| 2016-12-29 | 2016-12-28 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 5.500 | 9 | 77.063 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -9.800 | 21.078 | |||||
| 2016-12-29 | 2016-12-27 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,4565 | -9.800 | -298 | 71.563 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 9.800 | 15 | 81.363 | ||||
| 2016-12-21 | 2016-12-20 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 30.878 | |||||
| 2016-12-21 | 2016-12-20 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,0001 | -10.000 | -300 | 71.563 | ||||
| 2016-12-21 | 2016-12-20 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 81.563 | ||||
| 2016-12-21 | 2016-12-19 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,64 | -8.635 | 0 | |||||
| 2016-12-21 | 2016-12-19 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6400 | 8.635 | 14 | 71.563 | ||||
| 2016-11-14 | 2016-11-10 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.200 | 40.878 | |||||
| 2016-11-14 | 2016-11-10 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,0674 | -10.200 | -307 | 62.921 | ||||
| 2016-11-14 | 2016-11-10 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.200 | 16 | 73.121 | ||||
| 2016-08-24 | 2016-08-22 | 4 | YOUNG TODD S. | ACAD | Stock Option (right to buy) | D | 34,32 | 200.000 | 200.000 | |||||
| 2016-08-18 | 2016-08-16 | 4 | HARRIGAN EDMUND | ACAD | Common Stock | D | 32,9700 | 1.000 | 33 | 1.000 | ||||
| 2016-08-12 | 2016-08-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,0000 | 1.169.877 | 38.606 | 22.337.275 | ||||
| 2016-08-12 | 2016-08-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 33,0000 | 133.153 | 4.394 | 3.029.953 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,78 | -2.625 | 0 | |||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,78 | -3.375 | 0 | |||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,78 | -645 | 0 | |||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,78 | -5.298 | 0 | |||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 35,0022 | -11.943 | -418 | 62.921 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,7800 | 2.625 | 18 | 74.864 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,7800 | 3.375 | 23 | 72.239 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,7800 | 645 | 4 | 68.864 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,7800 | 5.298 | 36 | 68.219 | ||||
| 2016-07-13 | 2016-07-11 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,78 | -4.057 | 5.298 | |||||
| 2016-07-13 | 2016-07-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 35,0016 | -4.057 | -142 | 62.921 | ||||
| 2016-07-13 | 2016-07-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,7800 | 4.057 | 28 | 66.978 | ||||
| 2016-06-13 | 2016-06-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Non-Qualified Stock Option (right to buy) | I | 39,60 | 26.500 | 26.500 | |||||
| 2016-06-10 | 2016-06-10 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 39,60 | 12.500 | 12.500 | |||||
| 2016-06-10 | 2016-06-10 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 39,60 | 12.500 | 12.500 | |||||
| 2016-06-10 | 2016-06-10 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 39,60 | 12.500 | 12.500 | |||||
| 2016-06-10 | 2016-06-10 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 39,60 | 12.500 | 12.500 | |||||
| 2016-06-09 | 2016-06-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 9,04 | -10.000 | 0 | |||||
| 2016-06-09 | 2016-06-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 9,04 | -6.637 | 0 | |||||
| 2016-06-09 | 2016-06-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 9,0400 | 10.000 | 90 | 149.476 | ||||
| 2016-06-09 | 2016-06-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 9,0400 | 6.637 | 60 | 139.476 | ||||
| 2016-04-20 | 2016-04-18 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,75 | -33.697 | 0 | |||||
| 2016-04-20 | 2016-04-18 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 33,5341 | -33.697 | -1.130 | 36.127 | ||||
| 2016-04-20 | 2016-04-18 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 1,7500 | 33.697 | 59 | 69.824 | ||||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,36 | 1,3600 | -10.000 | -14 | 0 | |||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,36 | 1,3600 | -55.147 | -75 | 0 | |||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,30 | 1,3000 | -57.692 | -75 | 0 | |||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,30 | 1,3000 | -10.000 | -13 | 0 | |||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 1,3600 | 10.000 | 14 | 132.839 | ||||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 1,3600 | 55.147 | 75 | 122.839 | ||||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 1,3000 | 57.692 | 75 | 67.692 | ||||
| 2016-04-07 | 2016-04-07 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 1,3000 | 10.000 | 13 | 10.000 | ||||
| 2016-04-01 | 2016-04-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,5484 | 262.253 | 7.487 | 21.167.398 | ||||
| 2016-04-01 | 2016-04-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,5484 | 28.647 | 818 | 2.896.800 | ||||
| 2016-04-01 | 2016-04-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,8202 | 10.818 | 301 | 20.905.145 | ||||
| 2016-04-01 | 2016-04-01 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,8202 | 1.182 | 33 | 2.868.153 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,7173 | 318.969 | 8.841 | 20.894.327 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,7173 | 34.844 | 966 | 2.866.971 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,5588 | 60.587 | 1.670 | 20.575.358 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 27,5588 | 6.618 | 182 | 2.832.127 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,5545 | 28.433 | 755 | 20.514.771 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,5545 | 3.106 | 82 | 2.825.509 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,4944 | 180.122 | 4.772 | 20.486.338 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,4944 | 19.676 | 521 | 2.822.403 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,2850 | 13.433 | 353 | 20.306.216 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,2850 | 1.467 | 39 | 2.802.727 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,6070 | 14.775 | 378 | 20.292.783 | ||||
| 2016-04-01 | 2016-03-31 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,6070 | 1.614 | 41 | 2.801.260 | ||||
| 2016-04-01 | 2016-03-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 26,3472 | 16.057 | 423 | 2.799.646 | ||||
| 2016-04-01 | 2016-03-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,9750 | 37.882 | 984 | 2.783.589 | ||||
| 2016-04-01 | 2016-03-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 25,9247 | 408.607 | 10.593 | 2.745.707 | ||||
| 2016-03-17 | 2016-03-15 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 19,65 | 600.000 | 600.000 | |||||
| 2016-03-17 | 2016-03-15 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 19,65 | 150.000 | 150.000 | |||||
| 2016-03-17 | 2016-03-15 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,65 | 150.000 | 150.000 | |||||
| 2016-03-17 | 2016-03-15 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 19,65 | 150.000 | 150.000 | |||||
| 2016-03-04 | 2016-03-02 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 15,37 | -7.000 | 0 | |||||
| 2016-03-04 | 2016-03-02 | 4 | Baity Glenn | ACAD | Common Stock | D | 20,7971 | -7.000 | -146 | 62.921 | ||||
| 2016-03-04 | 2016-03-02 | 4 | Baity Glenn | ACAD | Common Stock | D | 15,3700 | 7.000 | 108 | 69.921 | ||||
| 2016-01-11 | 2016-01-07 | 4 | Daly James M | ACAD | Stock Option (right to buy) | D | 28,73 | 15.000 | 15.000 | |||||
| 2016-01-08 | 2016-01-07 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 29,0000 | 1.801.161 | 52.234 | 20.278.008 | ||||
| 2016-01-08 | 2016-01-07 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 29,0000 | 785.045 | 22.766 | 2.337.100 | ||||
| 2016-01-08 | 2016-01-07 | 4 | 14159, L.P. See Footnotes | ACAD | Common Stock | I | 29,0000 | 1.801.161 | 52.234 | 20.278.008 | ||||
| 2016-01-08 | 2016-01-07 | 4 | 14159, L.P. See Footnotes | ACAD | Common Stock | I | 29,0000 | 785.045 | 22.766 | 2.337.100 | ||||
| 2015-12-15 | 2015-12-11 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 32,50 | 15.000 | 15.000 | |||||
| 2015-11-30 | 2015-11-25 | 4 | HARRIGAN EDMUND | ACAD | Stock Option (right to buy) | D | 38,28 | 15.000 | 15.000 | |||||
| 2015-11-30 | 2015-11-25 | 4 | Stankovic Srdjan R. | ACAD | Stock Option (right to buy) | D | 38,28 | 250.000 | 250.000 | |||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,75 | -4.874 | 33.697 | |||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 9,04 | -9.126 | 0 | |||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 9,04 | -10.000 | 0 | |||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 9,04 | -6.000 | 0 | |||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 36,0109 | -30.000 | -1.080 | 36.127 | ||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 1,7500 | 4.874 | 9 | 66.127 | ||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 9,0400 | 9.126 | 82 | 61.253 | ||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 9,0400 | 10.000 | 90 | 52.127 | ||||
| 2015-11-13 | 2015-11-11 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 9,0400 | 6.000 | 54 | 42.127 | ||||
| 2015-09-03 | 2015-09-01 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 35,91 | 225.000 | 225.000 | |||||
| 2015-08-21 | 2015-08-19 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 11,00 | -8.500 | 0 | |||||
| 2015-08-21 | 2015-08-19 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 11,0000 | 8.500 | 94 | 36.127 | ||||
| 2015-08-21 | 2015-08-19 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 11,00 | -8.500 | 0 | |||||
| 2015-08-21 | 2015-08-19 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 11,0000 | 8.500 | 94 | 36.127 | ||||
| 2015-08-13 | 2015-08-11 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 11,00 | -8.500 | 0 | |||||
| 2015-08-13 | 2015-08-11 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 11,0000 | 8.500 | 94 | 17.000 | ||||
| 2015-06-17 | 2015-06-15 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 39,06 | 14.000 | 14.000 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-17 | 2015-06-15 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 39,06 | 12.500 | 12.500 | |||||
| 2015-06-03 | 2015-06-01 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 8,85 | -7.627 | 0 | |||||
| 2015-06-03 | 2015-06-01 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 8,85 | -6.500 | 0 | |||||
| 2015-06-03 | 2015-06-01 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 8,8500 | 7.627 | 67 | 27.627 | ||||
| 2015-06-03 | 2015-06-01 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 8,8500 | 6.500 | 58 | 20.000 | ||||
| 2015-03-24 | 2015-03-20 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 34,45 | 120.000 | 120.000 | |||||
| 2015-03-24 | 2015-03-20 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 34,45 | 100.000 | 100.000 | |||||
| 2015-03-24 | 2015-03-20 | 4 | SOLAND DANIEL B | ACAD | Stock Option (right to buy) | D | 34,45 | |||||||
| 2015-03-24 | 2015-03-20 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 34,45 | 180.000 | 180.000 | |||||
| 2015-03-24 | 2015-03-20 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 34,45 | 120.000 | 120.000 | |||||
| 2015-03-24 | 2015-03-20 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 34,45 | 120.000 | 120.000 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,36 | -10.000 | 0 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 8,49 | -7.067 | 0 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 8,49 | -2.780 | 0 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 35,0453 | -19.847 | -696 | 8.500 | ||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,3600 | 10.000 | 14 | 28.347 | ||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 8,4900 | 7.067 | 60 | 18.347 | ||||
| 2015-02-19 | 2015-02-17 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 8,4900 | 2.780 | 24 | 11.280 | ||||
| 2015-02-19 | 2015-02-17 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,55 | -30.000 | 313.500 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 34,2956 | -30.000 | -1.029 | 115.549 | ||||
| 2015-02-19 | 2015-02-17 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2015-02-19 | 2015-02-17 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2015-02-19 | 2015-02-17 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,5500 | 30.000 | 46 | 30.000 | ||||
| 2015-02-13 | 2015-02-11 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,75 | -10.000 | 0 | |||||
| 2015-02-13 | 2015-02-11 | 4 | Brege Laura | ACAD | Common Stock | D | 33,6349 | -10.000 | -336 | 0 | ||||
| 2015-02-13 | 2015-02-11 | 4 | Brege Laura | ACAD | Common Stock | D | 1,7500 | 10.000 | 18 | 10.000 | ||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 15,02 | -2.996 | 0 | |||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 15,02 | -10.000 | 0 | |||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 9,04 | -10.000 | 0 | |||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 9,04 | -4.977 | 0 | |||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 33,0235 | -27.973 | -924 | 0 | ||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 15,0200 | 2.996 | 45 | 27.973 | ||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 15,0200 | 10.000 | 150 | 24.977 | ||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 9,0400 | 4.977 | 45 | 14.977 | ||||
| 2015-01-16 | 2015-01-15 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 9,0400 | 10.000 | 90 | 10.000 | ||||
| 2015-01-16 | 2015-01-14 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -30.000 | 0 | |||||
| 2015-01-16 | 2015-01-14 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 33,9810 | -30.000 | -1.019 | 115.549 | ||||
| 2015-01-16 | 2015-01-14 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2015-01-16 | 2015-01-14 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2015-01-16 | 2015-01-14 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 30.000 | 60 | 30.000 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 8,49 | -7.220 | 2.780 | |||||
| 2015-01-15 | 2015-01-13 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 15,02 | -4.685 | 0 | |||||
| 2015-01-15 | 2015-01-13 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 35,0001 | -11.905 | -417 | 8.500 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 8,4900 | 7.220 | 61 | 20.405 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 15,0200 | 4.685 | 70 | 13.185 | ||||
| 2015-01-15 | 2015-01-13 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 11,00 | -4.250 | 0 | |||||
| 2015-01-15 | 2015-01-13 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 35,0000 | -4.250 | -149 | 0 | ||||
| 2015-01-15 | 2015-01-13 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 11,0000 | 4.250 | 47 | 4.250 | ||||
| 2014-12-17 | 2014-12-15 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -30.000 | 30.000 | |||||
| 2014-12-17 | 2014-12-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30,9972 | -30.000 | -930 | 115.549 | ||||
| 2014-12-17 | 2014-12-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2014-12-17 | 2014-12-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2014-12-17 | 2014-12-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 30.000 | 60 | 30.000 | ||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 11,00 | -4.250 | 4.250 | |||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 8,85 | -6.500 | 0 | |||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 7,67 | -1.500 | 0 | |||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 31,7400 | -12.250 | -389 | 0 | ||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 11,0000 | 4.250 | 47 | 12.250 | ||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 8,8500 | 6.500 | 58 | 8.000 | ||||
| 2014-12-17 | 2014-12-15 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 7,6700 | 1.500 | 12 | 1.500 | ||||
| 2014-12-10 | 2014-12-09 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -8.000 | 52.000 | |||||
| 2014-12-10 | 2014-12-09 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 8.000 | 12 | 62.423 | ||||
| 2014-11-26 | 2014-11-26 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 11,00 | -15.000 | 0 | |||||
| 2014-11-26 | 2014-11-26 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 30,0510 | -15.000 | -451 | 0 | ||||
| 2014-11-26 | 2014-11-26 | 4 | BORER MICHAEL T | ACAD | Common Stock | D | 11,0000 | 15.000 | 165 | 15.000 | ||||
| 2014-11-26 | 2014-11-26 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 1,55 | -25.000 | 139.035 | |||||
| 2014-11-26 | 2014-11-26 | 4 | Mills Roger | ACAD | Common Stock | D | 30,0906 | -25.000 | -752 | 18.550 | ||||
| 2014-11-26 | 2014-11-26 | 4 | Mills Roger | ACAD | Common Stock | D | 25.000 | 43.550 | ||||||
| 2014-11-26 | 2014-11-24 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -30.000 | 60.000 | |||||
| 2014-11-26 | 2014-11-24 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 29,2799 | -30.000 | -878 | 115.549 | ||||
| 2014-11-26 | 2014-11-24 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2014-11-26 | 2014-11-24 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2014-11-26 | 2014-11-24 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 30.000 | 60 | 30.000 | ||||
| 2014-11-21 | 2014-11-21 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,36 | -5.810 | 9.117 | |||||
| 2014-11-21 | 2014-11-21 | 4 | Wells William McDowall | ACAD | Common Stock | D | 29,0000 | -5.810 | -168 | 0 | ||||
| 2014-11-21 | 2014-11-21 | 4 | Wells William McDowall | ACAD | Common Stock | D | 1,3600 | 5.810 | 8 | 5.810 | ||||
| 2014-10-10 | 2014-10-08 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -30.000 | 90.000 | |||||
| 2014-10-10 | 2014-10-08 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 24,1510 | -30.000 | -725 | 115.549 | ||||
| 2014-10-10 | 2014-10-08 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2014-10-10 | 2014-10-08 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2014-10-10 | 2014-10-08 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 30.000 | 60 | 30.000 | ||||
| 2014-09-16 | 2014-09-12 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,36 | -9.190 | 14.927 | |||||
| 2014-09-16 | 2014-09-12 | 4 | Wells William McDowall | ACAD | Common Stock | D | 29,1483 | -9.190 | -268 | 0 | ||||
| 2014-09-16 | 2014-09-12 | 4 | Wells William McDowall | ACAD | Common Stock | D | 1,3600 | 9.190 | 12 | 9.190 | ||||
| 2014-09-16 | 2014-09-15 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,75 | -10.000 | 10.000 | |||||
| 2014-09-16 | 2014-09-15 | 4 | Brege Laura | ACAD | Common Stock | D | 28,0669 | -10.000 | -281 | 0 | ||||
| 2014-09-16 | 2014-09-15 | 4 | Brege Laura | ACAD | Common Stock | D | 1,7500 | 10.000 | 18 | 10.000 | ||||
| 2014-09-12 | 2014-09-10 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -30.000 | 120.000 | |||||
| 2014-09-12 | 2014-09-10 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 27,3607 | -30.000 | -821 | 115.549 | ||||
| 2014-09-12 | 2014-09-10 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 30.000 | 145.549 | ||||||
| 2014-09-12 | 2014-09-10 | 4 | Hacksell Uli | ACAD | Common Stock | D | -30.000 | 0 | ||||||
| 2014-09-12 | 2014-09-10 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 30.000 | 60 | 30.000 | ||||
| 2014-09-09 | 2014-09-05 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 26,96 | 25.000 | 25.000 | |||||
| 2014-09-04 | 2014-09-02 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 1,30 | -57.692 | 0 | |||||
| 2014-09-04 | 2014-09-02 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 26,7600 | -57.692 | -1.544 | 8.500 | ||||
| 2014-09-04 | 2014-09-02 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 1,3000 | 57.692 | 75 | 66.192 | ||||
| 2014-09-04 | 2014-09-02 | 4 | Wells William McDowall | ACAD | Stock option (right to buy) | D | 1,36 | -20.000 | 24.117 | |||||
| 2014-09-04 | 2014-09-02 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,36 | -10.000 | 0 | |||||
| 2014-09-04 | 2014-09-02 | 4 | Wells William McDowall | ACAD | Common Stock | D | 27,0000 | -15.000 | -405 | 0 | ||||
| 2014-09-04 | 2014-09-02 | 4 | Wells William McDowall | ACAD | Common Stock | D | 26,7600 | -15.000 | -401 | 15.000 | ||||
| 2014-09-04 | 2014-09-02 | 4 | Wells William McDowall | ACAD | Common Stock | D | 1,3600 | 30.000 | 41 | 30.000 | ||||
| 2014-08-15 | 2014-08-15 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,86 | -15.000 | 0 | |||||
| 2014-08-15 | 2014-08-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 22,8914 | -15.000 | -343 | 115.549 | ||||
| 2014-08-15 | 2014-08-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 15.000 | 130.549 | ||||||
| 2014-08-15 | 2014-08-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | -15.000 | 0 | ||||||
| 2014-08-15 | 2014-08-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,8600 | 15.000 | 103 | 15.000 | ||||
| 2014-07-16 | 2014-07-15 | 4 | DAVIS STEPHEN | ACAD | Stock Option (right to buy) | D | 20,77 | 320.000 | 320.000 | |||||
| 2014-07-16 | 2014-07-14 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,86 | -20.000 | 15.000 | |||||
| 2014-07-16 | 2014-07-14 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 22,2187 | -20.000 | -444 | 115.549 | ||||
| 2014-07-16 | 2014-07-14 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 20.000 | 135.549 | ||||||
| 2014-07-16 | 2014-07-14 | 4 | Hacksell Uli | ACAD | Common Stock | D | -20.000 | 0 | ||||||
| 2014-07-16 | 2014-07-14 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,8600 | 20.000 | 137 | 20.000 | ||||
| 2014-06-18 | 2014-06-16 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,86 | -20.000 | 35.000 | |||||
| 2014-06-18 | 2014-06-16 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 23,1002 | -20.000 | -462 | 115.549 | ||||
| 2014-06-18 | 2014-06-16 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 20.000 | 135.549 | ||||||
| 2014-06-18 | 2014-06-16 | 4 | Hacksell Uli | ACAD | Common Stock | D | -20.000 | 0 | ||||||
| 2014-06-18 | 2014-06-16 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,8600 | 20.000 | 137 | 20.000 | ||||
| 2014-06-10 | 2014-06-06 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-06 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-06 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-06 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 21,99 | 14.000 | 14.000 | |||||
| 2014-06-10 | 2014-06-06 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-06 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-06 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-10 | 2014-06-09 | 4 | Wells William McDowall | ACAD | Stock option (right to buy) | D | 1,60 | -15.000 | 0 | |||||
| 2014-06-10 | 2014-06-09 | 4 | Wells William McDowall | ACAD | Common Stock | D | 23,0304 | -15.000 | -345 | 0 | ||||
| 2014-06-10 | 2014-06-09 | 4 | Wells William McDowall | ACAD | Common Stock | D | 1,6000 | 15.000 | 24 | 15.000 | ||||
| 2014-06-10 | 2014-06-06 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 21,99 | 12.500 | 12.500 | |||||
| 2014-06-04 | 2014-06-02 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 6,10 | -4.450 | 0 | |||||
| 2014-06-04 | 2014-06-02 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 20,5249 | -4.450 | -91 | 8.500 | ||||
| 2014-06-04 | 2014-06-02 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 6,1000 | 4.450 | 27 | 12.950 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 15,02 | -5.315 | 4.685 | |||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 9,04 | -10.000 | 0 | |||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 11,00 | -8.500 | 0 | |||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 8,85 | -2.542 | 0 | |||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 8,85 | -6.500 | 0 | |||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 20,0333 | -32.857 | -658 | 8.500 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 15,0200 | 5.315 | 80 | 41.357 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 9,0400 | 10.000 | 90 | 36.042 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 11,0000 | 8.500 | 94 | 26.042 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 8,8500 | 2.542 | 22 | 17.542 | ||||
| 2014-05-02 | 2014-05-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 8,8500 | 6.500 | 58 | 15.000 | ||||
| 2014-04-17 | 2014-04-15 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,95 | -25.000 | 0 | |||||
| 2014-04-17 | 2014-04-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 17,7534 | -25.000 | -444 | 115.549 | ||||
| 2014-04-17 | 2014-04-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 25.000 | 140.549 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | -25.000 | 0 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,9500 | 25.000 | 174 | 25.000 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,75 | -15.500 | 27.357 | |||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,75 | -10.000 | 0 | |||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 6,10 | -4.500 | 0 | |||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 21,9795 | -30.000 | -659 | 8.500 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,7500 | 15.500 | 27 | 38.500 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,7500 | 10.000 | 18 | 23.000 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 6,1000 | 4.500 | 27 | 13.000 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -7.500 | 82.971 | |||||
| 2014-04-04 | 2014-04-04 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 22,4840 | -15.000 | -337 | 0 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 15.000 | 15.000 | ||||||
| 2014-04-04 | 2014-04-04 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -15.000 | 23.848 | ||||||
| 2014-04-04 | 2014-04-04 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 7.500 | 12 | 38.848 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,75 | -14.285 | 20.000 | |||||
| 2014-04-04 | 2014-04-04 | 4 | Brege Laura | ACAD | Common Stock | D | 22,5359 | -14.285 | -322 | 0 | ||||
| 2014-04-04 | 2014-04-04 | 4 | Brege Laura | ACAD | Common Stock | D | 1,7500 | 14.285 | 25 | 14.285 | ||||
| 2014-03-11 | 2014-03-07 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 27,20 | 250.000 | 250.000 | |||||
| 2014-03-11 | 2014-03-07 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 27,20 | 155.000 | 155.000 | |||||
| 2014-03-11 | 2014-03-07 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 27,20 | 35.000 | 35.000 | |||||
| 2014-03-11 | 2014-03-07 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 27,20 | 115.000 | 115.000 | |||||
| 2014-03-07 | 2014-03-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,5000 | 11.738 | 335 | 452.540 | ||||
| 2014-03-07 | 2014-03-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,5000 | 475.644 | 13.556 | 18.476.847 | ||||
| 2014-03-07 | 2014-03-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | ACAD | Common Stock | I | 28,5000 | 38.934 | 1.110 | 1.552.055 | ||||
| 2014-02-28 | 2014-02-26 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 6,17 | -42.000 | 0 | |||||
| 2014-02-28 | 2014-02-26 | 4 | Baity Glenn | ACAD | Common Stock | D | 30,2790 | -42.000 | -1.272 | 47.788 | ||||
| 2014-02-28 | 2014-02-26 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,1700 | 42.000 | 259 | 89.788 | ||||
| 2014-02-20 | 2014-02-18 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,95 | -25.000 | 25.000 | |||||
| 2014-02-20 | 2014-02-18 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 24,1411 | -25.000 | -604 | 115.549 | ||||
| 2014-02-20 | 2014-02-18 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 25.000 | 140.549 | ||||||
| 2014-02-20 | 2014-02-18 | 4 | Hacksell Uli | ACAD | Common Stock | D | -25.000 | 0 | ||||||
| 2014-02-20 | 2014-02-18 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,9500 | 25.000 | 174 | 25.000 | ||||
| 2014-01-17 | 2014-01-15 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 6,95 | -25.000 | 50.000 | |||||
| 2014-01-17 | 2014-01-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 24,0115 | -25.000 | -600 | 115.549 | ||||
| 2014-01-17 | 2014-01-15 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 25.000 | 140.549 | ||||||
| 2014-01-17 | 2014-01-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | -25.000 | 0 | ||||||
| 2014-01-17 | 2014-01-15 | 4 | Hacksell Uli | ACAD | Common Stock | D | 6,9500 | 25.000 | 174 | 25.000 | ||||
| 2014-01-17 | 2014-01-15 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,36 | -10.000 | 0 | |||||
| 2014-01-17 | 2014-01-15 | 4 | Brege Laura | ACAD | Common Stock | D | 24,1764 | -10.000 | -242 | 0 | ||||
| 2014-01-17 | 2014-01-15 | 4 | Brege Laura | ACAD | Common Stock | D | 1,3600 | 10.000 | 14 | 10.000 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -22.000 | 90.471 | |||||
| 2014-01-03 | 2014-01-02 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 24,8778 | -30.000 | -746 | 0 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 30.000 | 30.000 | ||||||
| 2014-01-03 | 2014-01-02 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -30.000 | 31.348 | ||||||
| 2014-01-03 | 2014-01-02 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 22.000 | 34 | 61.348 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,30 | -29.500 | 0 | |||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 2,16 | -20.500 | 7.277 | |||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 2,16 | -10.000 | 0 | |||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 25,0292 | -60.000 | -1.502 | 13.500 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 1,3000 | 29.500 | 38 | 73.500 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 2,1600 | 20.500 | 44 | 44.000 | ||||
| 2014-01-03 | 2014-01-02 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 2,1600 | 10.000 | 22 | 23.500 | ||||
| 2013-12-18 | 2013-12-17 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,55 | -6.500 | 343.500 | |||||
| 2013-12-18 | 2013-12-17 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 6.500 | 115.549 | ||||||
| 2013-12-18 | 2013-12-17 | 4 | Hacksell Uli | ACAD | Common Stock | D | -6.500 | 0 | ||||||
| 2013-12-18 | 2013-12-17 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,5500 | 6.500 | 10 | 6.500 | ||||
| 2013-12-16 | 2013-12-12 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 6,95 | -1.000 | 25.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -11.000 | 112.471 | |||||
| 2013-12-16 | 2013-12-12 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 6,9500 | 1.000 | 7 | 39.348 | ||||
| 2013-12-16 | 2013-12-12 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 11.000 | 17 | 38.348 | ||||
| 2013-12-16 | 2013-12-02 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -2.000 | 27.348 | ||||||
| 2013-12-12 | 2013-12-10 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,36 | -44.117 | 0 | |||||
| 2013-12-12 | 2013-12-10 | 4 | Brege Laura | ACAD | Common Stock | D | 23,4130 | -44.117 | -1.033 | 0 | ||||
| 2013-12-12 | 2013-12-10 | 4 | Brege Laura | ACAD | Common Stock | D | 1,3600 | 44.117 | 60 | 44.117 | ||||
| 2013-12-04 | 2013-12-02 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -15.000 | 0 | |||||
| 2013-12-04 | 2013-12-02 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 23,4538 | -15.000 | -352 | 109.049 | ||||
| 2013-12-04 | 2013-12-02 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 15.000 | 124.049 | ||||||
| 2013-12-04 | 2013-12-02 | 4 | Hacksell Uli | ACAD | Common Stock | D | -15.000 | 0 | ||||||
| 2013-12-04 | 2013-12-02 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 15.000 | 30 | 15.000 | ||||
| 2013-11-01 | 2013-11-01 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,00 | -15.000 | 15.000 | |||||
| 2013-11-01 | 2013-11-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 23,2425 | -15.000 | -349 | 109.049 | ||||
| 2013-11-01 | 2013-11-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 15.000 | 124.049 | ||||||
| 2013-11-01 | 2013-11-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | -15.000 | 0 | ||||||
| 2013-11-01 | 2013-11-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | 2,0000 | 15.000 | 30 | 15.000 | ||||
| 2013-11-01 | 2013-11-01 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,30 | -37.692 | 0 | |||||
| 2013-11-01 | 2013-11-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 23,0031 | -37.692 | -867 | 8.500 | ||||
| 2013-11-01 | 2013-11-01 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,3000 | 37.692 | 49 | 46.192 | ||||
| 2013-10-11 | 2013-10-10 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,30 | -10.000 | 0 | |||||
| 2013-10-11 | 2013-10-10 | 4 | Brege Laura | ACAD | Common Stock | D | 21,6256 | -10.000 | -216 | 0 | ||||
| 2013-10-11 | 2013-10-10 | 4 | Brege Laura | ACAD | Common Stock | D | 1,3000 | 10.000 | 13 | 10.000 | ||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -17.500 | 123.471 | |||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 6,95 | -5.000 | 26.000 | |||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 27,8707 | -30.000 | -836 | 0 | ||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 30.000 | 30.000 | ||||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -30.000 | 24.085 | ||||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 17.500 | 27 | 54.085 | ||||
| 2013-10-03 | 2013-10-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 6,9500 | 5.000 | 35 | 36.585 | ||||
| 2013-09-20 | 2013-09-20 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 1,55 | -35.965 | 164.035 | |||||
| 2013-09-20 | 2013-09-20 | 4 | Mills Roger | ACAD | Common Stock | D | 25,0052 | -35.965 | -899 | 15.775 | ||||
| 2013-09-20 | 2013-09-20 | 4 | Mills Roger | ACAD | Common Stock | D | 35.965 | 51.740 | ||||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 2,16 | -34.722 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 9,04 | -10.000 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 2,16 | -10.000 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 8,85 | -5.084 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 8,85 | -6.500 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 6,10 | -50 | 4.450 | |||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 22,9018 | -66.356 | -1.520 | 8.500 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 2,1600 | 34.722 | 75 | 74.856 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 2,1600 | 10.000 | 22 | 40.134 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 9,0400 | 10.000 | 90 | 30.134 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 8,8500 | 5.084 | 45 | 20.134 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 8,8500 | 6.500 | 58 | 15.050 | ||||
| 2013-09-13 | 2013-09-12 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 6,1000 | 50 | 0 | 8.550 | ||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,30 | -45.500 | 29.500 | |||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,30 | -10.000 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 6,10 | -4.500 | 0 | |||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 22,9245 | -60.000 | -1.375 | 13.500 | ||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 1,3000 | 45.500 | 59 | 73.500 | ||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 1,3000 | 10.000 | 13 | 28.000 | ||||
| 2013-09-13 | 2013-09-12 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 6,1000 | 4.500 | 27 | 18.000 | ||||
| 2013-09-12 | 2013-09-10 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,30 | -46.153 | 0 | |||||
| 2013-09-12 | 2013-09-10 | 4 | Brege Laura | ACAD | Common Stock | D | 22,7969 | -46.153 | -1.052 | 0 | ||||
| 2013-09-12 | 2013-09-10 | 4 | Brege Laura | ACAD | Common Stock | D | 1,3000 | 46.153 | 60 | 46.153 | ||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,30 | -20.000 | 37.692 | |||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 2,16 | -10.000 | 0 | |||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,30 | -10.000 | 0 | |||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 20,2775 | -40.000 | -811 | 8.500 | ||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,3000 | 20.000 | 26 | 48.500 | ||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 1,3000 | 10.000 | 13 | 28.500 | ||||
| 2013-09-05 | 2013-09-03 | 4 | Rasmussen Torsten | ACAD | Common Stock | I | 2,1600 | 10.000 | 22 | 18.500 | ||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 8,49 | -10.000 | 0 | |||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 7,67 | -5.000 | 1.500 | |||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 20,7129 | -10.000 | -207 | 0 | ||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 20,6164 | -5.000 | -103 | 10.000 | ||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 8,4900 | 10.000 | 85 | 15.000 | ||||
| 2013-08-28 | 2013-08-26 | 4 | GRAY MARY ANN | ACAD | Common Stock | D | 7,6700 | 5.000 | 38 | 5.000 | ||||
| 2013-08-20 | 2013-08-19 | 4 | Moore Terrence O | ACAD | Stock Option (right to buy) | D | 19,61 | 150.000 | 150.000 | |||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -17.771 | 0 | |||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -35.000 | 0 | |||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 20,1448 | -52.771 | -1.063 | 109.049 | ||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 52.771 | 161.820 | ||||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli | ACAD | Common Stock | D | -52.771 | 0 | ||||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 17.771 | 19 | 52.771 | ||||
| 2013-08-15 | 2013-08-13 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 35.000 | 38 | 35.000 | ||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -15.000 | 58.708 | |||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -30.000 | 82.263 | |||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 20,1530 | -60.000 | -1.209 | 0 | ||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 60.000 | 60.000 | ||||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -60.000 | 31.585 | ||||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 15.000 | 23 | 91.585 | ||||
| 2013-08-15 | 2013-08-13 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 30.000 | 46 | 76.585 | ||||
| 2013-06-11 | 2013-06-07 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 17,01 | 14.000 | 14.000 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 17,01 | 300.000 | 300.000 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 17,01 | 175.000 | 175.000 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 17,01 | 175.000 | 175.000 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 17,01 | 130.000 | 130.000 | |||||
| 2013-06-11 | 2013-06-07 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | BAKER BROS. ADVISORS LP | ACAD | Non-Qualified Stock Option (right to buy) | I | 17,01 | 12.500 | 12.500 | |||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4641 | 5.437 | 79 | 440.802 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4641 | 217.986 | 3.153 | 18.001.203 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4641 | 26.577 | 384 | 1.513.121 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5502 | 3.790 | 55 | 435.365 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5502 | 151.980 | 2.211 | 17.783.217 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5502 | 18.530 | 270 | 1.486.544 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5838 | 4.312 | 63 | 431.575 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5838 | 172.893 | 2.521 | 17.631.237 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,5838 | 21.080 | 307 | 1.468.014 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4565 | 5.437 | 79 | 427.263 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4565 | 217.986 | 3.151 | 17.458.344 | ||||
| 2013-06-05 | 2013-06-05 | 4 | BAKER FELIX | ACAD | Common Stoc | I | 14,4565 | 26.577 | 384 | 1.446.934 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4159 | 2.775 | 40 | 421.826 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4159 | 111.266 | 1.604 | 17.240.358 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4159 | 13.566 | 196 | 1.420.357 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4525 | 11.552 | 167 | 419.051 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4525 | 463.197 | 6.694 | 17.129.092 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4525 | 56.475 | 816 | 1.406.791 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4977 | 890 | 13 | 407.499 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4977 | 35.702 | 518 | 16.665.895 | ||||
| 2013-06-05 | 2013-06-04 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,4977 | 4.353 | 63 | 1.350.316 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 13,9990 | 5.189 | 73 | 406.609 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 13,9990 | 208.063 | 2.913 | 16.630.193 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 13,9990 | 25.368 | 355 | 1.345.963 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,0822 | 11.511 | 162 | 401.420 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,0822 | 461.548 | 6.500 | 16.422.130 | ||||
| 2013-06-05 | 2013-06-03 | 4 | BAKER FELIX | ACAD | Common Stock | I | 14,0822 | 56.274 | 792 | 1.320.595 | ||||
| 2013-05-17 | 2013-05-15 | 4 | BAKER FELIX | ACAD | Common Stock | I | 12,5000 | 43.184 | 540 | 389.909 | ||||
| 2013-05-17 | 2013-05-15 | 4 | BAKER FELIX | ACAD | Common Stock | I | 12,5000 | 1.730.970 | 21.637 | 15.960.582 | ||||
| 2013-05-17 | 2013-05-15 | 4 | BAKER FELIX | ACAD | Common Stock | I | 12,5000 | 218.846 | 2.736 | 1.264.321 | ||||
| 2013-05-03 | 2013-05-02 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -20.449 | 35.000 | |||||
| 2013-05-03 | 2013-05-02 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 12,3427 | -20.449 | -252 | 109.049 | ||||
| 2013-05-03 | 2013-05-02 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 20.449 | 129.498 | ||||||
| 2013-05-03 | 2013-05-02 | 4 | Hacksell Uli | ACAD | Common Stock | D | -20.449 | 0 | ||||||
| 2013-05-03 | 2013-05-02 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 20.449 | 22 | 20.449 | ||||
| 2013-05-03 | 2013-05-01 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -19.551 | 55.449 | |||||
| 2013-05-03 | 2013-05-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 12,7113 | -19.551 | -249 | 109.049 | ||||
| 2013-05-03 | 2013-05-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 19.551 | 128.600 | ||||||
| 2013-05-03 | 2013-05-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | -19.551 | 0 | ||||||
| 2013-05-03 | 2013-05-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 19.551 | 21 | 19.551 | ||||
| 2013-04-24 | 2013-04-22 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -10.000 | 22.407 | |||||
| 2013-04-24 | 2013-04-22 | 4 | Baity Glenn | ACAD | Common Stock | D | 13,1493 | -10.000 | -131 | 40.000 | ||||
| 2013-04-24 | 2013-04-22 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 10.000 | 16 | 50.000 | ||||
| 2013-04-17 | 2013-04-16 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -16.729 | 75.000 | |||||
| 2013-04-17 | 2013-04-16 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 12,3168 | -16.729 | -206 | 109.049 | ||||
| 2013-04-17 | 2013-04-16 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 16.729 | 125.778 | ||||||
| 2013-04-17 | 2013-04-16 | 4 | Hacksell Uli | ACAD | Common Stock | D | -16.729 | 0 | ||||||
| 2013-04-17 | 2013-04-16 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 16.729 | 18 | 16.729 | ||||
| 2013-04-17 | 2013-04-17 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 59.078 | |||||
| 2013-04-17 | 2013-04-17 | 4 | Baity Glenn | ACAD | Common Stock | D | 12,2600 | -10.000 | -123 | 40.000 | ||||
| 2013-04-17 | 2013-04-17 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 50.000 | ||||
| 2013-04-17 | 2013-04-16 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 922 | |||||
| 2013-04-17 | 2013-04-16 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 922 | |||||
| 2013-04-17 | 2013-04-16 | 4 | Baity Glenn | ACAD | Common Stock | D | 12,3000 | -20.000 | -246 | 40.000 | ||||
| 2013-04-17 | 2013-04-16 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-17 | 2013-04-16 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-17 | 2013-04-15 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 10.922 | |||||
| 2013-04-17 | 2013-04-15 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 10.922 | |||||
| 2013-04-17 | 2013-04-15 | 4 | Baity Glenn | ACAD | Common Stock | D | 12,5000 | -20.000 | -250 | 40.000 | ||||
| 2013-04-17 | 2013-04-15 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-17 | 2013-04-15 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,55 | -14.029 | 73.708 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 2,00 | -12.500 | 0 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,08 | -7.500 | 0 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 11,0600 | -40.000 | -442 | 0 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 40.000 | 40.000 | ||||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -40.000 | 44.500 | ||||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5500 | 14.029 | 22 | 84.500 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 2,0000 | 12.500 | 25 | 70.471 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,0800 | 7.500 | 8 | 57.971 | ||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -10.000 | 32.407 | |||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 32.407 | |||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 20.922 | |||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 13,0000 | -10.000 | -130 | 40.000 | ||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 10.000 | 16 | 50.000 | ||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 12,7400 | -20.000 | -255 | 40.000 | ||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-12 | 2013-04-12 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 60.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 42.407 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,62 | -10.000 | 42.407 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,55 | -10.000 | 30.922 | |||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 13,0000 | -10.000 | -130 | 40.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,6200 | 10.000 | 16 | 50.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 12,0000 | -10.000 | -120 | 40.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 50.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 1,5500 | 10.000 | 16 | 50.000 | ||||
| 2013-04-12 | 2013-04-11 | 4 | Baity Glenn | ACAD | Common Stock | D | 11,0600 | -10.000 | -111 | 40.000 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -40.000 | 91.729 | |||||
| 2013-04-03 | 2013-04-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 7,6761 | -40.000 | -307 | 109.049 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 40.000 | 149.049 | ||||||
| 2013-04-03 | 2013-04-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | -40.000 | 0 | ||||||
| 2013-04-03 | 2013-04-01 | 4 | Hacksell Uli | ACAD | Common Stock | D | 1,0800 | 40.000 | 43 | 40.000 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,08 | -36.490 | 7.500 | |||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,08 | -3.510 | 0 | |||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 7,6771 | -40.000 | -307 | 0 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 40.000 | 40.000 | ||||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -40.000 | 50.471 | ||||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,0800 | 36.490 | 39 | 90.471 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,0800 | 3.510 | 4 | 53.981 | ||||
| 2013-04-03 | 2013-04-01 | 4 | Mills Roger | ACAD | Common Stock | D | 7,6875 | -58.584 | -450 | 14.017 | ||||
| 2013-04-03 | 2013-04-02 | 4 | Baity Glenn | ACAD | Common Stock | D | 8,0000 | -13.163 | -105 | 40.000 | ||||
| 2013-02-22 | 2013-02-21 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,08 | -4.500 | 0 | |||||
| 2013-02-22 | 2013-02-21 | 4 | Iversen Leslie L | ACAD | Common Stock | D | 4.500 | 13.500 | ||||||
| 2013-01-23 | 3 | Baker Brothers Life Sciences LP | ACAD | Common Stock | D | 14.229.612 | ||||||||
| 2013-01-23 | 3 | 14159, L.P. | ACAD | Common Stock | D | 346.725 | ||||||||
| 2013-01-23 | 3 | 667, L.P. | ACAD | Common Stock | D | 1.045.475 | ||||||||
| 2013-01-23 | 2013-01-18 | 4 | BAKER FELIX | ACAD | Stock Options (right to buy) | I | 5,22 | 15.000 | 15.000 | |||||
| 2013-01-18 | 2013-01-18 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,08 | -7.500 | 0 | |||||
| 2013-01-18 | 2013-01-18 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 7.500 | 109.049 | ||||||
| 2013-01-18 | 2013-01-18 | 4 | Hacksell Uli | ACAD | Common Stock | D | -7.500 | 0 | ||||||
| 2013-01-18 | 2013-01-18 | 4 | Hacksell Uli | ACAD | Common Stock | D | 7.500 | 7.500 | ||||||
| 2013-01-18 | 2013-01-17 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,08 | -12.000 | 43.990 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,0800 | 12.000 | 13 | 50.471 | ||||
| 2013-01-15 | 2013-01-14 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 1,08 | -4.500 | 0 | |||||
| 2013-01-15 | 2013-01-14 | 4 | KAPLAN LESTER J PH D | ACAD | Common Stock | D | 1,0800 | 4.500 | 5 | 8.500 | ||||
| 2013-01-10 | 2013-01-10 | 4 | Rasmussen Torsten See footnote (1) | ACAD | Stock option (right to buy) | I | 1,08 | -4.500 | 0 | |||||
| 2013-01-10 | 2013-01-10 | 4 | Rasmussen Torsten | ACAD | Common stock | I | 1,0800 | 4.500 | 5 | 8.500 | ||||
| 2012-12-21 | 3 | BAKER JULIAN See Footnotes | ACAD | Common Stock | I | 14.229.612 | ||||||||
| 2012-12-21 | 3 | BAKER JULIAN See Footnotes | ACAD | Common Stock | I | 1.045.475 | ||||||||
| 2012-12-21 | 3 | BAKER JULIAN See Footnotes | ACAD | Common Stock | I | 346.725 | ||||||||
| 2012-11-29 | 2012-11-28 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,08 | -5.000 | 3.510 | |||||
| 2012-11-29 | 2012-11-28 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 5,2499 | -9.100 | -48 | 0 | ||||
| 2012-11-29 | 2012-11-28 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 5.000 | 9.100 | ||||||
| 2012-11-29 | 2012-11-28 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -5.000 | 28.471 | ||||||
| 2012-11-29 | 2012-11-28 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,0800 | 5.000 | 5 | 33.471 | ||||
| 2012-11-29 | 2012-11-27 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 6,2414 | -30.900 | -193 | 4.100 | ||||
| 2012-11-29 | 2012-11-27 | 4 | Aasen Thomas H By Family Trust | ACAD | Common Stock | I | 33.631 | 35.000 | ||||||
| 2012-11-29 | 2012-11-27 | 4 | Aasen Thomas H | ACAD | Common Stock | D | -33.631 | 28.471 | ||||||
| 2012-11-29 | 2012-11-28 | 4 | Baity Glenn | ACAD | Common Stock | D | 5,2526 | -4.396 | -23 | 43.163 | ||||
| 2012-11-29 | 2012-11-27 | 4 | Baity Glenn | ACAD | Common Stock | D | 6,2788 | -16.206 | -102 | 47.559 | ||||
| 2012-09-11 | 2012-09-07 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,50 | -7.500 | 20.000 | |||||
| 2012-09-11 | 2012-09-07 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5000 | 7.500 | 11 | 62.102 | ||||
| 2012-08-22 | 2012-08-22 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,50 | -23.333 | 0 | |||||
| 2012-08-22 | 2012-08-22 | 4 | Hacksell Uli By Family Trust | ACAD | Common Stock | I | 23.333 | 101.549 | ||||||
| 2012-08-22 | 2012-08-22 | 4 | Hacksell Uli | ACAD | Common Stock | D | -23.333 | 0 | ||||||
| 2012-08-22 | 2012-08-22 | 4 | Hacksell Uli | ACAD | Common Stock | D | 23.333 | 23.333 | ||||||
| 2012-08-06 | 2012-08-03 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,50 | -5.000 | 27.500 | |||||
| 2012-08-06 | 2012-08-03 | 4 | Aasen Thomas H | ACAD | Common Stock | D | 1,5000 | 5.000 | 8 | 54.602 | ||||
| 2012-06-11 | 2012-06-08 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 1,36 | 55.147 | 55.147 | |||||
| 2012-06-11 | 2012-06-08 | 4 | KAPLAN LESTER J PH D | ACAD | Stock option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 1,36 | 22.058 | 22.058 | |||||
| 2012-06-11 | 2012-06-08 | 4 | BORER MICHAEL T | ACAD | Stock Option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,36 | 55.147 | 55.147 | |||||
| 2012-06-11 | 2012-06-08 | 4 | GRAY MARY ANN | ACAD | Stock option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Rasmussen Torsten | ACAD | Stock option (right to buy) | I | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,36 | 93.750 | 93.750 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Iversen Leslie L | ACAD | Stock option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,36 | 44.117 | 44.117 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Brege Laura | ACAD | Stock option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,36 | 44.117 | 44.117 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,36 | 10.000 | 10.000 | |||||
| 2012-03-26 | 2012-03-23 | 4/A | Baity Glenn | ACAD | Stock Option (right to buy) | D | 2,18 | 130.000 | 130.000 | |||||
| 2012-03-26 | 2012-03-23 | 4/A | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 2,18 | 175.000 | 175.000 | |||||
| 2012-03-26 | 2012-03-23 | 4/A | Mills Roger | ACAD | Stock Option (right to buy) | D | 2,18 | 175.000 | 175.000 | |||||
| 2012-03-26 | 2012-03-23 | 4/A | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 2,18 | 300.000 | 300.000 | |||||
| 2012-03-26 | 2012-03-23 | 4 | Hacksell Uli | ACAD | Stock Option (right to buy) | D | 1,18 | 300.000 | 300.000 | |||||
| 2012-03-26 | 2012-03-23 | 4 | Aasen Thomas H | ACAD | Stock Option (right to buy) | D | 1,18 | 175.000 | 175.000 | |||||
| 2012-03-26 | 2012-03-23 | 4 | Mills Roger | ACAD | Stock Option (right to buy) | D | 1,18 | 175.000 | 175.000 | |||||
| 2012-03-26 | 2012-03-23 | 4 | Baity Glenn | ACAD | Stock Option (right to buy) | D | 1,18 | 130.000 | 130.000 | |||||
| 2012-01-31 | 2012-01-27 | 4 | Wells William McDowall | ACAD | Stock Option (right to buy) | D | 1,60 | 15.000 | 15.000 | |||||
| 2010-03-16 | 3 | Baity Glenn | ACAD | Common Stock | D | 30.203 | ||||||||
| 2008-06-17 | 2008-06-13 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 8,49 | 8.833 | 8.833 | |||||
| 2008-06-17 | 2008-06-13 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 8,49 | 10.000 | 10.000 | |||||
| 2008-03-11 | 2008-03-07 | 4 | Hacksell Uli | ACAD | Srock option (right to buy) | D | 8,32 | 60.000 | 60.000 | |||||
| 2008-03-11 | 2008-03-07 | 4 | Aasen Thomas H | ACAD | Stock option (right to buy) | D | 8,32 | 26.000 | 26.000 | |||||
| 2008-03-11 | 2008-03-07 | 4 | Tolf Bo-Ragnar | ACAD | Stock option (right to buy) | D | 8,32 | 21.000 | 21.000 | |||||
| 2007-06-19 | 2007-06-15 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 15,02 | 3.994 | 3.994 | |||||
| 2007-06-19 | 2007-06-15 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 15,02 | 10.000 | 10.000 | |||||
| 2006-06-15 | 2006-06-13 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 9,04 | 16.637 | 16.637 | |||||
| 2005-09-13 | 2005-09-09 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 11,00 | 8.500 | 8.500 | |||||
| 2005-08-26 | 3 | Nomura Phase4 Ventures LP Notes | ACAD | Common Stock, par value $0.0001 per share ("Common Stock") | I | 2.199.010 | ||||||||
| 2005-08-02 | 2005-07-29 | 4 | OXFORD BIOSCIENCE PARTNERS IV LP | ACAD | Common Stock Warrant (right to buy) | D | 8,15 | 3,0900 | 89.900 | 278 | 236.500 | |||
| 2005-06-14 | 2005-06-10 | 4 | Binder Gordon M | ACAD | Stock Option (Right to Buy) | D | 8,85 | 6.500 | 6.500 | |||||
| 2005-06-14 | 2005-06-10 | 4 | KAPLAN LESTER J PH D | ACAD | Stock Option (Right to Buy) | D | 8,85 | 5.084 | 5.084 | |||||
| 2005-06-14 | 2005-06-10 | 4 | KAPLAN LESTER J PH D | ACAD | Stock Option (Right to Buy) | D | 8,85 | 6.500 | 6.500 | |||||
| 2005-06-14 | 2005-06-10 | 4 | Rasmussen Torsten Please see footnote. | ACAD | Stock Option (Right to Buy) | I | 8,85 | 2.542 | 2.542 | |||||
| 2005-06-14 | 2005-06-10 | 4 | Rasmussen Torsten Please see footnote. | ACAD | Stock Option (Right to Buy) | I | 8,85 | 6.500 | 6.500 | |||||
| 2005-06-14 | 2005-06-09 | 4 | Iversen Leslie L | ACAD | Stock Option (Right to Buy) | D | 8,85 | 7.627 | 7.627 | |||||
| 2005-06-14 | 2005-06-09 | 4 | Iversen Leslie L | ACAD | Stock Option (Right to Buy) | D | 8,85 | 6.500 | 6.500 | |||||
| 2005-06-14 | 2005-06-10 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 8,85 | 5.084 | 5.084 | |||||
| 2005-06-14 | 2005-06-10 | 4 | WALTON ALAN G | ACAD | Stock Option (Right to Buy) | D | 8,85 | 6.500 | 6.500 | |||||
| 2005-04-22 | 2005-04-20 | 4 | GORDON CARL L | ACAD | Common Stock Warrant (Right to Buy) | I | 8,15 | 0,0313 | 89.900 | 3 | 89.900 | |||
| 2005-04-22 | 2005-04-20 | 4 | GORDON CARL L | ACAD | Common Stock | I | 6,7900 | 359.603 | 2.442 | 774.006 | ||||
| 2005-04-22 | 2005-04-20 | 4 | van Osch Martien | ACAD | Common Stock Warrant (Right to Buy) | I | 8,15 | 0,0313 | 91.625 | 3 | 91.625 | |||
| 2005-04-22 | 2005-04-20 | 4 | van Osch Martien | ACAD | Common Stock | I | 6,7900 | 366.501 | 2.489 | 1.168.892 | ||||
| 2005-04-21 | 2005-04-20 | 4 | OXFORD BIOSCIENCE PARTNERS IV LP | ACAD | Common Stock Warrant (right to buy) | D | 8,15 | 146.600 | 146.600 | |||||
| 2005-04-21 | 2005-04-20 | 4 | OXFORD BIOSCIENCE PARTNERS IV LP | ACAD | Common Stock | D | 6,8213 | 586.402 | 4.000 | 3.160.238 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
