Cytokinetics, Incorporated
US ˙ NasdaqGS ˙ US23282W6057

Introduktion

Denne side giver en omfattende analyse af den kendte insiderhandelshistorie for B Lynne Parshall. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Det er ulovligt for insidere at foretage handler i deres virksomheder baseret på specifik, ikke-offentlig information. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4. På trods af disse begrænsninger tyder akademisk forskning på, at insidere - generelt - har en tendens til at klare sig bedre end markedet i deres egne virksomheder.

Gennemsnitlig handelsrentabilitet

Den gennemsnitlige handelsrentabilitet er det gennemsnitlige afkast af alle køb på det åbne marked foretaget af insideren i de sidste tre år. For at beregne dette undersøger vi ethvert åbent marked, uplanlagte køb foretaget af insideren, eksklusive alle handler, der var markeret som en del af en 10b5-1-handelsplan. Vi beregner derefter den gennemsnitlige præstation for disse handler over 3, 6 og 12 måneder, idet vi tager et gennemsnit af hver af disse varigheder for at generere en endelig præstationsmåling for hver handel. Endelig tager vi et gennemsnit af alle præstationsmålingerne for at beregne en præstationsmåling for insideren. Denne liste inkluderer kun insidere, der har foretaget mindst tre handler i de sidste to år.

Hvis denne insiderhandelsrentabilitet er "N/A", så har insideren enten ikke foretaget nogen køb på det åbne marked i de sidste tre år, eller de handler, de har foretaget, er for nye til at beregne en pålidelig præstationsmåling.

Opdateringsfrekvens: Dagligt

Se listen over de mest profitable insiderhandlere.

Virksomheder med rapporterede insider-stillinger

SEC-registreringen viser, at B Lynne Parshall har rapporteret besiddelser eller handler i følgende virksomheder:

Sikkerhed Titel Senest indberettede beholdninger
US:IONS / Ionis Pharmaceuticals, Inc. Director 66.344
US:CYTK / Cytokinetics, Incorporated Director 27.933
Director 0
US:RGLS / Regulus Therapeutics Inc. Director 5.516.305
Sådan fortolkes diagrammerne

Følgende diagrammer viser aktieudviklingen for værdipapirer efter hver åben-marked, ikke-planlagt handel foretaget af B Lynne Parshall. Ikke-planlagt handel er handler, der ikke blev foretaget som en del af en 10b5-1-handelsplan. Aktieudviklingen er kortlagt som den kumulative procentvise ændring i aktiekursen. For eksempel, hvis en insiderhandel blev foretaget den 1. januar 2019, vil diagrammet vise den daglige procentvise ændring af værdipapiret til i dag. Hvis aktiekursen skulle gå fra $10 til $15 i løbet af denne tid, ville den kumulative procentvise ændring i aktiekursen være 50%. En prisændring fra 10 USD til 20 USD ville være 100 %, og en ændring i prisen på 10 USD til 5 USD ville være -50 %.

I sidste ende forsøger vi at bestemme, hvor tæt insiderens handler korrelerer med merafkast (positive eller negative) i aktiekursen for at se, om insideren timing deres handler til at drage fordel af insiderinformation. Overvej situationen, hvor en insider gjorde dette. I denne situation ville vi forvente enten (a) positive afkast efter køb eller (b) negative afkast efter salg. I tilfælde af (a) vil KØB-diagrammet vise en række opadskrånende kurver, der indikerer positive afkast efter hver købstransaktion. I tilfælde af (b) vil SALE-diagrammet vise en række nedadgående kurver, der indikerer negative afkast efter hver salgstransaktion.

Dette alene er dog ikke nok til at drage konklusioner. Hvis for eksempel aktiekursen i selskabet var i en ikke-cyklisk stigning over mange år, så ville vi forvente, at alle efterkøbsgrundene var opadgående. Ligeledes ville ikke-cykliske fald over mange år resultere i nedadgående post-trade plots. Ingen af disse diagrammer tyder på insiderhandel.

Den stærkeste indikator ville være en situation, hvor aktiekursen var ekstremt cyklisk, og der var både positive signaler i KØB-diagrammet og negative plots på SALG-diagrammet. Denne situation ville i høj grad tyde på en insider, der havde timing af handler til deres økonomiske fordel.

Insiderkøb CYTK / Cytokinetics, Incorporated – kortsigtet profitanalyse

I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i CYTK / Cytokinetics, Incorporated. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato Ticker Insider Rapporteret
Aktier
Rapporteret
Pris
Justeret
Aktier
Justeret
Pris
Omkostningsgrundlag dage til
Maks
Pris kl
Maks
Maks
Fortjeneste ($)
Maks. afkast (%)
Der er ingen kendte uplanlagte åbne markedshandler for denne insider- og sikkerhedskombination

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

CYTK / Cytokinetics, Incorporated Insider Trades
Insidersalg CYTK / Cytokinetics, Incorporated – kortsigtet tabsanalyse

I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i CYTK / Cytokinetics, Incorporated. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato Ticker Insider Rapporteret
Aktier
Rapporteret
Pris
Justeret
Aktier
Justeret
Pris
Omkostningsgrundlag dage til
Min
Pris kl
Min
Max tab
Undgået ($)
Max tab
Undgået (%)
2024-09-09 CYTK PARSHALL B LYNNE 5.000 54,9200 5.000 54,9200 274.600 248 29.8400 -125.400 -45,67
2024-08-26 CYTK PARSHALL B LYNNE 5.000 57,2600 5.000 57,2600 286.300
2024-08-12 CYTK PARSHALL B LYNNE 5.000 55,2000 5.000 55,2000 276.000
2024-07-29 CYTK PARSHALL B LYNNE 5.000 59,8400 5.000 59,8400 299.200
2024-07-15 CYTK PARSHALL B LYNNE 5.000 55,8200 5.000 55,8200 279.100
2024-07-01 CYTK PARSHALL B LYNNE 5.000 54,2200 5.000 54,2200 271.100
2024-06-17 CYTK PARSHALL B LYNNE 5.000 52,5500 5.000 52,5500 262.750
2024-06-03 CYTK PARSHALL B LYNNE 5.000 48,6400 5.000 48,6400 243.200
2020-06-22 CYTK PARSHALL B LYNNE 10.000 25,0000 10.000 25,0000 250.000
2020-06-22 CYTK PARSHALL B LYNNE 6.510 25,0000 6.510 25,0000 162.750

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

CYTK / Cytokinetics, Incorporated Insider Trades
Insiderkøb IONS / Ionis Pharmaceuticals, Inc. – kortsigtet profitanalyse

I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i CYTK / Cytokinetics, Incorporated. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato Ticker Insider Rapporteret
Aktier
Rapporteret
Pris
Justeret
Aktier
Justeret
Pris
Omkostningsgrundlag dage til
Maks
Pris kl
Maks
Maks
Fortjeneste ($)
Maks. afkast (%)
Der er ingen kendte uplanlagte åbne markedshandler for denne insider- og sikkerhedskombination

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insidersalg IONS / Ionis Pharmaceuticals, Inc. – kortsigtet tabsanalyse

I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i CYTK / Cytokinetics, Incorporated. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato Ticker Insider Rapporteret
Aktier
Rapporteret
Pris
Justeret
Aktier
Justeret
Pris
Omkostningsgrundlag dage til
Min
Pris kl
Min
Max tab
Undgået ($)
Max tab
Undgået (%)
2023-12-28 IONS PARSHALL B LYNNE 42.525 50,1875 42.525 50,1875 2.134.223 326 33.7300 -699.855 -32,79
2023-12-27 IONS PARSHALL B LYNNE 50.000 50,2303 50.000 50,2303 2.511.515
2023-12-26 IONS PARSHALL B LYNNE 25.113 51,4630 25.113 51,4630 1.292.390
2018-01-16 IONS PARSHALL B LYNNE 5.986 51,7600 5.986 51,7600 309.835
2017-01-17 IONS PARSHALL B LYNNE 965 46,2902 965 46,2902 44.670
2017-01-17 IONS PARSHALL B LYNNE 1.509 46,2895 1.509 46,2895 69.851
2017-01-17 IONS PARSHALL B LYNNE 2.696 46,2895 2.696 46,2895 124.796
2017-01-17 IONS PARSHALL B LYNNE 2.076 46,2893 2.076 46,2893 96.097
2016-12-15 IONS PARSHALL B LYNNE 1.000 50,0000 1.000 50,0000 50.000
2016-01-19 IONS PARSHALL B LYNNE 667 41,4594 667 41,4594 27.653
2016-01-19 IONS PARSHALL B LYNNE 1.003 41,4658 1.003 41,4658 41.590
2016-01-19 IONS PARSHALL B LYNNE 1.219 41,4556 1.219 41,4556 50.534
2016-01-19 IONS PARSHALL B LYNNE 2.303 41,4584 2.303 41,4584 95.479
2015-01-16 ISIS PARSHALL B LYNNE 903 67,9640 903 67,9640 61.371
2015-01-16 ISIS PARSHALL B LYNNE 1.372 67,9640 1.372 67,9640 93.247
2015-01-16 ISIS PARSHALL B LYNNE 1.818 67,9640 1.818 67,9640 123.559
2014-01-16 ISIS PARSHALL B LYNNE 653 47,0823 653 47,0823 30.745
2014-01-16 ISIS PARSHALL B LYNNE 988 47,0826 988 47,0826 46.518
2013-04-23 ISIS PARSHALL B LYNNE 10.000 22,0967 10.000 22,0967 220.967
2013-04-23 ISIS PARSHALL B LYNNE 10.000 22,0967 10.000 22,0967 220.967
2013-04-23 ISIS PARSHALL B LYNNE 10.000 22,0967 10.000 22,0967 220.967
2013-01-16 ISIS PARSHALL B LYNNE 759 14,0000 759 14,0000 10.626

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insiderhandelshistorie

Denne tabel viser den komplette liste over insiderhandler foretaget af B Lynne Parshall som oplyst til Securities Exchange Commission (SEC).

Fil dato Transdato Form Ticker Sikkerhed Kode 10b5-1 Aktier Resterende aktier Procent
Lave om
Del
Pris
Tran
Værdi
Tilbage
Værdi
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -9.250 66.344 -12,24 51,49 -476.282 3.416.053
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.750 75.594 -12,45 50,42 -542.015 3.811.449
2025-08-08 2025-08-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -400 86.344 -0,46 42,63 -17.051 3.680.629
2025-08-08 2025-08-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.600 86.744 -5,04 41,87 -192.595 3.631.841
2025-07-17 2025-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.079 91.344 4,67
2025-05-15 2025-05-14 4 CYTK CYTOKINETICS INC
Common Stock
A - Award 7.333 27.933 35,60
2024-09-09 2024-09-09 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 54,92 -274.600 1.131.352
2024-09-09 2024-09-09 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 21,61 108.050 553.216
2024-08-26 2024-08-26 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 57,26 -286.300 1.179.556
2024-08-26 2024-08-26 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 21,61 108.050 553.216
2024-08-12 2024-08-12 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 55,20 -276.000 1.137.120
2024-08-12 2024-08-12 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 21,61 108.050 553.216
2024-07-31 2024-07-29 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 59,84 -299.200 1.232.704
2024-07-31 2024-07-29 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 21,61 108.050 553.216
2024-07-17 2024-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.677 87.265 5,66
2024-07-16 2024-07-15 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 55,82 -279.100 1.149.892
2024-07-16 2024-07-15 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 10,68 53.400 273.408
2024-07-01 2024-07-01 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 54,22 -271.100 1.116.932
2024-07-01 2024-07-01 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 10,68 53.400 273.408
2024-06-17 2024-06-17 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 20.600 -19,53 52,55 -262.750 1.082.530
2024-06-17 2024-06-17 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 25.600 24,27 10,68 53.400 273.408
2024-06-04 2024-06-03 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -5.000 15.600 -24,27 48,64 -243.200 758.784
2024-06-04 2024-06-03 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 5.000 20.600 32,05 10,68 53.400 220.008
2024-05-16 2024-05-15 4 CYTK CYTOKINETICS INC
Common Stock
A - Award 5.600 20.600 37,33
2023-12-28 2023-12-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -42.525 82.588 -33,99 50,19 -2.134.223 4.144.885
2023-12-28 2023-12-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 42.525 125.113 51,49 47,34 2.013.134 5.922.849
2023-12-28 2023-12-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -50.000 82.588 -37,71 50,23 -2.511.515 4.148.420
2023-12-28 2023-12-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 50.000 132.588 60,54 47,34 2.367.000 6.276.716
2023-12-28 2023-12-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -25.113 82.588 -23,32 51,46 -1.292.390 4.250.226
2023-12-28 2023-12-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 25.113 107.701 30,41 47,34 1.188.849 5.098.565
2023-09-28 2023-09-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 82.588 -10,80 45,13 -451.268 3.726.932
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 92.588 6,11
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.777 87.255 2,08
2023-05-18 2023-05-10 4 CYTK CYTOKINETICS INC
Common Stock
A - Award 5.000 15.000 50,00
2022-09-01 2022-09-01 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -30.296 10.000 -75,18 52,79 -1.599.326 527.900
2022-09-01 2022-09-01 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 4.582 40.296 12,83 6,82 31.249 274.819
2022-09-01 2022-09-01 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 20.000 35.714 127,28 9,45 189.000 337.497
2022-09-01 2022-09-01 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 5.714 15.714 57,14 8,75 49.998 137.498
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.665 85.478 3,22
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 82.813 6,88
2022-05-11 2022-05-10 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 10.000 10.000
2022-05-11 2022-05-10 4 CYTK CYTOKINETICS INC
Common Stock
A - Award 5.000 10.000 100,00
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -5.754 9.775 -37,05
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -1.652 77.480 -2,09 30,12 -49.758 2.333.698
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.754 79.132 7,84
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -20.000 0 -100,00
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -4.032 0 -100,00
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -2.798 0 -100,00
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -4.166 0 -100,00
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -2.798 5.000 -35,88 40,00 -111.920 200.000
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 2.798 7.798 55,96 6,84 19.138 53.338
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -4.166 5.000 -45,45 40,00 -166.640 200.000
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 4.166 9.166 83,32 6,78 28.245 62.145
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -4.032 5.000 -44,64 40,00 -161.280 200.000
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 4.032 9.032 80,64 12,40 49.997 111.997
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -20.000 5.000 -80,00 40,00 -800.000 200.000
2021-11-05 2021-11-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 20.000 25.000 400,00 14,25 285.000 356.250
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -1.999 2.798 -41,67
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -8.333 0 -100,00
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -8.333 5.000 -62,50 35,73 -297.774 178.672
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 8.333 13.333 166,66 6,60 54.998 87.998
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -1.999 5.000 -28,56 35,73 -71.433 178.672
2021-10-20 2021-10-19 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 1.999 6.999 39,98 6,84 13.673 47.873
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -1.778 15.529 -10,27
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -889 17.307 -4,89
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -5.333 18.196 -22,67
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 73.378 2,48
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 71.600 1,26
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 70.711 8,16
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
A - Award 5.333 23.529 29,31
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
A - Award 12.000 12.000
2021-05-13 2021-05-12 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 10.000 10.000
2021-05-13 2021-05-12 4 CYTK CYTOKINETICS INC
Common Stock
A - Award 5.000 5.000
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -10.655 5.754 -64,93
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -2.741 65.378 -4,02 61,28 -167.968 4.006.364
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10.655 68.119 18,54
2020-12-28 2020-12-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 57.464 -14,82 60,00 -600.000 3.447.840
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -3.590 0 -100,00
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.590 67.464 -5,05 50,05 -179.680 3.376.573
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.590 71.054 5,32 39,87 143.133 2.832.923
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -710 3.590 -16,51
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -710 67.464 -1,04 50,82 -36.082 3.428.520
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 710 68.174 1,05 39,87 28.308 2.718.097
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -3.200 4.300 -42,67
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.200 67.464 -4,53 50,12 -160.384 3.381.296
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.200 70.664 4,74 39,87 127.584 2.817.374
2020-10-13 2020-10-12 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
D - Sale to Issuer -26.400 0 -100,00 2,01 -53.064
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -4.375 0 -100,00 4,00 -17.500
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -20.000 0 -100,00
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -20.000 0 -100,00
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise X -5.936 0 -100,00
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -5.936 0 -100,00 30,00 -178.080
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 5.936 5.936 7,37 43.748 43.748
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -20.000 0 -100,00 30,00 -600.000
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -20.000 0 -100,00 30,00 -600.000
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 20.000 20.000 6,21 124.200 124.200
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale X -4.375 0 -100,00 30,00 -131.250
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 4.375 4.375 10,00 43.750 43.750
2020-10-06 2020-10-05 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise X 20.000 20.000 7,61 152.200 152.200
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 1.777 -33,35
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 67.464 1,34
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 12.000 12.000
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5.333 5.333
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.778 5.332 -25,01
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 66.575 2,74
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -6.510 0 -100,00
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -6.510 0 -100,00 25,00 -162.750
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 6.510 6.510 6,72 43.747 43.747
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Common Stock
S - Sale -10.000 0 -100,00 25,00 -250.000
2020-06-23 2020-06-22 4 CYTK CYTOKINETICS INC
Common Stock
M - Exercise 10.000 10.000 4,44 44.400 44.400
2020-05-14 2020-05-13 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 20.000 20.000 21,61 432.200 432.200
2020-04-15 2020-04-13 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 26.400 26.400
2020-02-14 2020-02-12 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 2.749 2.749 15,43 42.417 42.417
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -15.136 16.409 -47,98
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -3.905 64.797 -5,68 62,06 -242.344 4.021.302
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 15.136 68.702 28,26
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 2.666 -25,01
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 53.566 1,69
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7.110 7.110
2019-06-18 2019-06-14 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 26.400 26.400
2019-05-17 2019-05-15 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 20.000 20.000 10,68 213.600 213.600
2019-05-01 2019-04-29 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 50.000 7.500 -117,65
2019-05-01 2019-04-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -50.000 52.677 -48,70 75,01 -3.750.635 3.951.444
2019-05-01 2019-04-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 50.000 102.677 94,92 39,87 1.993.500 4.093.732
2019-03-14 2019-03-12 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 8.334 57.500 16,95
2019-03-14 2019-03-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.334 52.677 -13,66 75,00 -625.050 3.950.775
2019-03-14 2019-03-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.334 61.011 15,82 39,87 332.277 2.432.509
2019-03-01 2019-02-27 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 8.333 65.834 14,49
2019-03-01 2019-02-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.333 52.677 -13,66 70,00 -583.310 3.687.390
2019-03-01 2019-02-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.333 61.010 15,82 39,87 332.237 2.432.469
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -20.656 35.100 -37,05
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -6.159 52.677 -10,47 58,26 -358.823 3.068.962
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 20.656 58.836 54,10
2019-01-04 2019-01-02 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 4.582 4.582 6,82 31.249 31.249
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3.555 3.555
2018-06-05 2018-06-01 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 26.400 26.400
2018-05-17 2018-05-16 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 20.000 20.000 9,45 189.000 189.000
2018-05-08 2018-05-07 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 53.000 53.000
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -5.986 38.180 -13,55 51,76 -309.835 1.976.197
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -18.339 29.185 -38,59
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 23.016 23.016
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 18.339 44.166 71,01
2018-01-04 2018-01-02 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 5.714 5.714 3,50 20.000 20.000
2018-01-02 2018-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 103.575 103.575
2018-01-02 2018-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 86 25.827 0,33 42,76 3.677 1.104.233
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -8.333 74.167 -10,10
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.785 0 -100,00
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.333 25.741 -24,46 65,00 -541.645 1.673.165
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.333 34.074 32,37 39,87 332.237 1.358.530
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.785 25.741 -23,22 65,00 -506.025 1.673.165
2017-10-20 2017-10-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.785 33.526 30,24 14,69 114.362 492.497
2017-07-13 3 AKCA AKCEA THERAPEUTICS, INC.
No securities are beneficially owned.
0
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 90 25.741 0,35 40,66 3.659 1.046.513
2017-05-22 2017-05-18 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 20.000 20.000
2017-03-02 2017-03-01 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -4.625 7.785 -37,27
2017-03-02 2017-03-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.625 25.651 -15,28 49,26 -227.828 1.263.568
2017-03-02 2017-03-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.625 30.276 18,03 14,69 67.941 444.754
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.076 25.651 -7,49 46,29 -96.097 1.187.367
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.696 23.245 -10,39 46,29 -124.796 1.075.999
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.509 20.422 -6,88 46,29 -69.851 945.324
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -965 18.494 -4,96 46,29 -44.670 856.091
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -4.482 13.443 -25,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -5.519 11.038 -33,33
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -3.437 3.437 -50,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.595 0 -100,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 19.606 19.606
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.482 27.727 19,28
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.519 25.941 27,02
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.437 21.931 18,58
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.595 19.459 15,39
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 117.638 117.638
2017-01-04 2017-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 171 16.864 1,02 20,76 3.549 350.046
2017-01-04 2017-01-03 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 4.032 4.032 4,96 20.000 20.000
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.000 20.693 5,08 7,25 7.250 150.024
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.000 20.693 -4,61 50,00 -50.000 1.034.650
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 0 -100,00 50,00 -50.000
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 0 -100,00 50,00 -50.000
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 0 -100,00 50,00 -50.000
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 1.000 7,25 7.250 7.250
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 1.000 7,25 7.250 7.250
2016-12-16 2016-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 1.000 7,25 7.250 7.250
2016-12-02 2016-12-01 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -12.500 12.410 -50,18
2016-12-02 2016-12-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.500 16.693 -24,78 43,17 -237.435 720.637
2016-12-02 2016-12-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.500 22.193 32,95 14,69 80.795 326.015
2016-12-02 2016-12-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.000 16.693 -29,54 41,49 -290.430 692.593
2016-12-02 2016-12-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.000 23.693 41,93 14,69 102.830 348.050
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -3.635 24.910 -12,73
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Options (right to buy)
M - Exercise -8.865 0 -100,00
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.635 16.693 -17,88 30,05 -109.232 501.625
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.635 20.328 21,78 14,69 53.398 298.618
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.865 16.693 -34,69 29,82 -264.314 497.708
2016-09-06 2016-09-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.865 25.558 53,11 7,25 64.271 185.296
2016-07-01 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 403 16.693 2,47 20,76 8.365 346.497
2016-05-20 2016-05-18 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 20.000 20.000
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.303 16.290 -12,39 41,46 -95.479 675.357
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.219 13.074 -8,53 41,46 -50.534 541.991
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.003 10.855 -8,46 41,47 -41.590 450.111
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -667 9.263 -6,72 41,46 -27.653 384.038
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -5.519 16.557 -25,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -3.438 6.874 -33,34
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.595 2.595 -50,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.715 0 -100,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 17.925 17.925
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.519 18.593 42,21
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.438 14.293 31,67
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.595 11.858 28,01
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.715 9.930 20,88
2016-01-06 2016-01-04 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 4.375 4.375 4,00 17.500 17.500
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -809 28.545 -2,76
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 107.549 107.549
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -809 8.215 -8,96 61,05 -49.389 501.526
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 809 9.024 9,85 14,69 11.884 132.563
2016-01-04 2016-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 72 8.215 0,88 47,71 3.435 391.942
2015-11-09 2015-11-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.000 1.000
2015-11-09 2015-11-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.000 1.000
2015-11-09 2015-11-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.000 1.000
2015-11-09 2015-11-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.000 1.000
2015-11-09 2015-11-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -4.000 8.865 -31,09
2015-10-05 2015-10-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.436 29.354 -15,63
2015-10-05 2015-10-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.436 8.143 -29,67 42,39 -145.667 345.218
2015-10-05 2015-10-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.436 11.579 42,20 14,69 50.475 170.096
2015-10-05 2015-10-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 8.143 -19,72 40,10 -80.200 326.534
2015-10-05 2015-10-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.000 10.143 24,56 14,69 29.380 149.001
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.838 34.790 -7,54
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -4.162 12.865 -24,44
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.838 8.143 -25,84 40,13 -113.877 326.744
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.838 10.981 34,85 14,69 41.690 161.311
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.162 8.143 -33,82 40,13 -167.003 326.744
2015-10-05 2015-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.162 12.305 51,11 7,25 30.174 89.211
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -4.843 17.027 -22,14
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.375 0 -100,00
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.843 8.143 -37,29 57,01 -276.085 464.208
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.843 12.986 59,47 7,25 35.112 94.148
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.375 8.143 -14,45 57,01 -78.385 464.208
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.375 9.518 16,89 10,29 14.149 97.940
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -6.218 1.375 -81,89
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.218 8.143 -43,30 57,56 -357.914 468.719
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.218 14.361 76,36 10,29 63.983 147.775
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 71 8.143 0,88 48,59 3.450 395.636
2015-05-21 2015-05-20 4 CYTK CYTOKINETICS INC
Stock Option (right to buy)
A - Award 20.000 20.000
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.565 37.628 -12,88
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.565 8.072 -40,81 63,07 -350.990 509.109
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.565 13.637 68,94 14,69 81.750 200.328
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.377 43.193 -11,07
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.377 8.072 -39,98 61,93 -333.009 499.916
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.377 13.449 66,61 14,69 78.988 197.566
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.818 8.072 -18,38 67,96 -123.559 548.605
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.372 6.452 -17,54 67,96 -93.247 438.504
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -903 5.229 -14,73 67,96 -61.371 355.384
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -3.438 10.312 -25,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.595 5.190 -33,33
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.715 1.715 -50,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 22.076 22.076
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.438 9.890 53,29
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.595 7.824 49,63
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.715 6.132 38,83
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -11.200 48.570 -18,74
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 132.458 132.458
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11.200 4.417 -71,72 62,12 -695.688 274.362
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11.200 15.617 253,57 14,69 164.528 229.414
2015-01-05 2015-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 111 4.417 2,58 30,05 3.335 132.720
2015-01-05 2015-01-02 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 5.936 5.936 2,95 17.511 17.511
2014-11-05 2014-11-03 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale -1.279.411 5.516.305 -18,83 15,94 -20.390.613 87.916.111
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -8.561 21.870 -28,13
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.510 59.770 -4,03
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.561 4.306 -66,53 45,12 -386.281 194.291
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.561 12.867 198,82 7,25 62.067 93.286
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.510 4.306 -36,83 45,12 -113.254 194.291
2014-10-31 2014-10-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.510 6.816 58,29 14,69 36.872 100.127
2014-10-24 2014-10-24 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.850 6.795.716 -0,03 15,19 -28.109 103.256.148
2014-10-24 2014-10-23 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.700 6.797.566 -0,03 14,24 -24.202 96.774.908
2014-10-24 2014-10-22 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -109.534 6.799.266 -1,59 14,00 -1.533.125 95.167.966
2014-10-17 2014-10-17 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.000 6.908.800 -0,04 6,79 -20.371 46.912.825
2014-10-17 2014-10-16 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -4.800 6.911.800 -0,07 6,76 -32.450 46.727.224
2014-10-17 2014-10-15 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -4.300 6.916.600 -0,06 6,67 -28.687 46.143.405
2014-10-10 2014-10-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.000 6.920.900 -0,03 6,41 -12.813 44.337.362
2014-10-10 2014-10-09 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -4.750 6.922.900 -0,07 6,58 -31.238 45.527.760
2014-10-10 2014-10-08 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.300 6.927.650 -0,05 6,63 -21.888 45.948.331
2014-10-03 2014-10-03 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.300 6.930.950 -0,05 6,88 -22.688 47.650.974
2014-10-03 2014-10-02 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.750 6.934.250 -0,05 6,64 -24.903 46.048.274
2014-10-03 2014-10-01 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.250 6.938.000 -0,05 6,71 -21.808 46.556.061
2014-09-26 2014-09-26 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.500 6.941.250 -0,04 7,04 -17.598 48.861.541
2014-09-26 2014-09-25 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.500 6.943.750 -0,04 7,12 -17.790 49.411.725
2014-09-26 2014-09-24 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.750 6.946.250 -0,05 7,19 -26.978 49.972.712
2014-09-19 2014-09-19 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -4.100 6.950.000 -0,06 7,22 -29.587 50.153.285
2014-09-19 2014-09-18 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.500 6.954.100 -0,02 7,40 -11.098 51.449.213
2014-09-19 2014-09-17 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.100 6.955.600 -0,03 7,43 -15.610 51.701.670
2014-09-12 2014-09-12 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.500 6.957.700 -0,05 7,96 -27.861 55.384.684
2014-09-12 2014-09-11 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.400 6.961.200 -0,05 7,83 -26.636 54.534.737
2014-09-12 2014-09-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.000 6.964.600 -0,03 7,70 -15.399 53.624.634
2014-09-05 2014-09-05 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.400 6.966.600 -0,03 7,07 -16.974 49.272.672
2014-09-05 2014-09-04 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -6.000 6.969.000 -0,09 7,11 -42.656 49.545.409
2014-09-05 2014-09-03 4 RGLS Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.650 6.975.000 -0,02 6,95 -11.471 48.489.502
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -443 30.431 -1,43
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.628 7.593 -58,33
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -443 4.306 -9,33 40,24 -17.827 173.277
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 443 4.749 10,29 7,25 3.212 34.430
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.628 4.306 -71,17 40,24 -427.680 173.277
2014-09-04 2014-09-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.628 14.934 246,82 10,29 109.362 153.671
2014-08-29 2014-08-29 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.500 6.976.650 -0,02 6,84 -10.254 47.692.379
2014-08-29 2014-08-28 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.000 6.978.150 -0,03 6,96 -13.921 48.570.715
2014-08-29 2014-08-27 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.500 6.980.150 -0,02 7,21 -10.821 50.356.896
2014-08-22 2014-08-22 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -5.250 6.981.650 -0,08 6,75 -35.443 47.133.119
2014-08-22 2014-08-21 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.500 6.986.900 -0,04 6,89 -17.222 48.132.055
2014-08-22 2014-08-20 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.000 6.989.400 -0,04 7,14 -21.424 49.912.703
2014-08-15 2014-08-15 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.450 6.992.400 -0,02 6,98 -10.115 48.779.682
2014-08-15 2014-08-14 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.750 6.993.850 -0,03 7,04 -12.324 49.252.790
2014-08-15 2014-08-13 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.250 6.995.600 -0,03 7,02 -15.788 49.086.027
2014-08-08 2014-08-08 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.850 6.997.850 -0,03 6,80 -12.583 47.595.177
2014-08-08 2014-08-07 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.600 6.999.700 -0,04 6,66 -17.322 46.634.101
2014-08-08 2014-08-06 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.150 7.002.300 -0,04 7,08 -22.300 49.572.083
2014-08-01 2014-08-01 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.600 7.005.450 -0,04 6,21 -16.152 43.521.358
2014-08-01 2014-07-31 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.750 7.008.050 -0,02 6,42 -11.235 44.990.279
2014-08-01 2014-07-30 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.000 7.009.800 -0,01 6,60 -6.602 46.279.401
2014-07-25 2014-07-25 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.700 7.010.800 -0,02 6,55 -11.137 45.927.050
2014-07-25 2014-07-24 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.850 7.012.500 -0,03 6,81 -12.598 47.753.021
2014-07-25 2014-07-23 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.700 7.014.350 -0,02 6,88 -11.702 48.283.278
2014-07-18 2014-07-18 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -5.000 7.016.050 -0,07 6,80 -34.001 47.710.543
2014-07-18 2014-07-17 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -5.000 7.021.050 -0,07 6,58 -32.906 46.206.934
2014-07-18 2014-07-16 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.500 7.026.050 -0,05 6,59 -23.058 46.288.320
2014-07-11 2014-07-11 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.750 7.029.550 -0,02 6,48 -11.339 45.549.375
2014-07-11 2014-07-10 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -4.500 7.031.300 -0,06 6,69 -30.109 47.045.022
2014-07-11 2014-07-09 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.800 7.035.800 -0,03 7,08 -12.748 49.830.350
2014-07-07 2014-07-03 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.200 7.037.600 -0,02 8,07 -9.678 56.760.355
2014-07-07 2014-07-02 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.100 7.038.800 -0,04 8,07 -25.011 56.789.038
2014-07-01 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 284 4.306 7,06 30,20 8.577 130.043
2014-06-27 2014-06-27 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -3.150 7.041.900 -0,04 7,91 -24.931 55.733.822
2014-06-27 2014-06-26 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -1.700 7.045.050 -0,02 7,89 -13.408 55.564.309
2014-06-27 2014-06-25 4 "RGLS" Regulus Therapeutics Inc.
Common Stock
S - Sale X -2.750 7.046.750 -0,04 7,84 -21.566 55.261.318
2014-05-22 2014-05-21 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 10.000 10.000
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -15.875 30.874 -33,96
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -23.635 18.221 -56,47
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -15.875 4.022 -79,79 50,36 -799.528 202.564
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15.875 19.897 394,70 7,25 115.094 144.253
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -23.635 4.022 -85,46 50,36 -1.190.353 202.564
2014-01-31 2014-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 23.635 27.657 587,64 10,29 243.204 284.591
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -31.028 41.856 -42,57
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -3.972 0 -100,00
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 48,81 -244.035
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 48,81 -244.035
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 7,25 36.250 36.250
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 7,25 36.250 36.250
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 7,25 36.250 36.250
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 48,81 -244.035
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -31.028 4.022 -88,52 48,81 -1.514.384 196.302
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 31.028 35.050 771,46 10,29 319.278 360.664
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.972 4.022 -49,69 48,81 -193.861 196.302
2014-01-31 2014-01-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.972 7.994 98,76 11,27 44.764 90.092
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 5.000 5.000
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -5.000 46.749 -9,66
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -988 4.022 -19,72 47,08 -46.518 189.366
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -653 2.415 -21,28 47,08 -30.745 113.704
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.595 7.785 -25,00
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.715 3.430 -33,33
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 13.750 13.750
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.595 5.010 107,45
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.715 3.068 126,76
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 82.500 82.500
2014-01-03 2014-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 5.000 5.000
2014-01-03 2014-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 5.000 5.000
2014-01-03 2014-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -10.000 51.749 -16,19
2014-01-03 2014-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 397 1.353 41,53 24,20 9.607 32.742
2014-01-03 2014-01-02 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 6.510 6.510 2,69 17.512 17.512
2013-12-30 2013-12-26 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -37.811 3.972 -90,49
2013-12-30 2013-12-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -37.811 956 -97,53 40,91 -1.546.772 39.108
2013-12-30 2013-12-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 37.811 38.767 3.955,13 11,27 426.130 436.904
2013-12-24 2013-12-24 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -20.000 41.783 -32,37
2013-12-24 2013-12-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -20.000 956 -95,44 41,00 -819.920 39.192
2013-12-24 2013-12-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20.000 20.956 2.092,05 11,27 225.400 236.174
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.771 61.783 -2,79
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -48.229 0 -100,00
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.771 956 -64,94 41,68 -73.817 39.847
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.771 2.727 185,25 11,27 19.959 30.733
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -48.229 956 -98,06 41,68 -2.010.233 39.847
2013-12-24 2013-12-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 48.229 49.185 5.044,87 14,47 697.874 711.707
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 48.229 -38,35
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 956 -91,27 35,90 -358.980 34.318
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 10.956 1.046,03 15,38 153.800 168.503
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 956 -96,91 35,90 -1.076.940 34.318
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 30.956 3.138,08 14,47 434.100 447.933
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 0 -100,00
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -20.000 10.000 -66,67
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 956 -96,91 35,02 -1.050.600 33.479
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 30.956 3.138,08 16,45 493.500 509.226
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -20.000 956 -95,44 35,12 -702.480 33.579
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20.000 20.956 2.092,05 15,38 307.600 322.303
2013-09-11 2013-09-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.520 30.000 -4,82
2013-09-11 2013-09-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.985 956 -67,49 31,18 -61.894 29.809
2013-09-11 2013-09-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.520 2.941 -34,07 31,18 -47.395 91.703
2013-09-11 2013-09-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.520 4.461 51,68 15,38 23.378 68.610
2013-09-11 2013-09-10 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 31.520 -48,76
2013-09-11 2013-09-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 2.941 -91,07 31,65 -949.440 93.077
2013-09-11 2013-09-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 32.941 1.020,06 15,38 461.400 506.633
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 61.520 -32,78
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 2.941 -91,07 30,42 -912.450 89.451
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 32.941 1.020,06 15,38 461.400 506.633
2013-05-29 2013-05-22 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 25.000 25.000
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -18.400 0 -100,00
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.454 0 -100,00
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -18.400 2.941 -86,22 22,50 -413.908 66.158
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 18.400 21.341 625,64 6,81 125.304 145.332
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.454 2.941 -71,71 22,50 -167.678 66.158
2013-04-26 2013-04-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.454 10.395 253,45 11,12 82.888 115.592
2013-04-26 2013-04-24 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 7.454 -80,10
2013-04-26 2013-04-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 2.941 -91,07 22,12 -663.600 65.055
2013-04-26 2013-04-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 32.941 1.020,06 11,12 333.600 366.304
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10.000 0 -100,00 22,10 -220.967
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10.000 0 -100,00 22,10 -220.967
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 10.000 6,81 68.100 68.100
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 10.000 6,81 68.100 68.100
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10.000 2.941 -77,27 22,10 -220.967 64.986
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 12.941 340,02 11,12 111.200 143.904
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 47.454 -38,73
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 2.941 -91,07 20,99 -629.700 61.732
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 32.941 1.020,06 11,12 333.600 366.304
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -30.000 0 -100,00
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -30.000 2.941 -91,07 20,01 -600.180 58.838
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30.000 32.941 1.020,06 7,26 217.800 239.152
2013-04-08 2013-04-01 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 28.782 28.782 0,46 13.125 13.125
2013-02-08 2013-02-07 4 CYTK CYTOKINETICS INC
Non-Qualified Stock Option (right to buy)
A - Award 50.000 50.000
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 62.280 62.280
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 10.380 10.380
2013-01-17 2013-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -759 2.941 -20,51 14,00 -10.626 41.174
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.715 5.145 -25,00
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.715 3.700 86,40
2013-01-11 2013-01-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 10.000 10.000
2013-01-11 2013-01-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 10.000 10.000
2013-01-11 2013-01-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -20.000 18.400 -52,08
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Series A Preferred Stock
C - Conversion -6.299.500 0 -100,00
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
P - Purchase 750.000 7.049.500 11,91 4,00 3.000.000 28.198.000
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
C - Conversion 6.299.500 6.299.500
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.506 0 -100,00
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,12 -75.600
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,12 -75.600
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 6,84 34.200 34.200
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 6,84 34.200 34.200
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.506 1.985 -55,80 15,12 -37.891 30.013
2012-09-11 2012-09-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.506 4.491 126,25 6,84 17.141 30.718
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 5.000 -50,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 5.000 -50,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 5.000 -50,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to uy)
M - Exercise -2.494 2.506 -49,88
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.506 0 -100,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,00 -75.010
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,00 -75.010
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 5,25 26.250 26.250
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 5,25 26.250 26.250
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,04 -75.175
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 0 -100,00 15,04 -75.175
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 6,84 34.200 34.200
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 5.000 6,84 34.200 34.200
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 1.985 -71,58 15,00 -75.010 29.779
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 6.985 251,89 5,25 26.250 36.671
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.506 1.985 -55,80 15,04 -37.678 29.844
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.506 4.491 126,25 5,25 13.156 23.578
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.494 1.985 -55,68 15,04 -37.497 29.844
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.494 4.479 125,64 6,84 17.059 30.636
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.000 7.506 -21,04
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 1.985 -50,19 15,00 -30.000 29.775
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.000 3.985 100,76 5,25 10.500 20.921
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 5.000 -66,67
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 5.000 -66,67
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 5.000 -66,67
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 0 -100,00 15,00 -150.010
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 0 -100,00 15,00 -150.010
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 10.000 5,25 52.500 52.500
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 10.000 5,25 52.500 52.500
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 1.985 -83,44 15,00 -150.010 29.777
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 11.985 503,78 5,25 52.500 62.921
2012-01-17 2012-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 6.860 6.860
2012-01-13 2012-01-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 10.000 15.000 200,00
2012-01-13 2012-01-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 10.000 15.000 200,00
2012-01-13 2012-01-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -20.000 19.506 -50,63
2012-01-03 2012-01-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 61.749 61.749
2010-01-05 2010-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 63.554 63.554
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)