Zymeworks Inc.
US ˙ NasdaqGS ˙ US98985Y1082

SecurityZYME / Zymeworks Inc.
InstitutionState Street Corp
Latest Disclosed Ownership1,011,777 shares
Latest Disclosed Value $ 25,334,896
State Street Corp reports 2.49% decrease in ownership of ZYME / Zymeworks Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 1,011,777 shares of Zymeworks Inc. (US:ZYME) valued at $25,334,896 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 1,037,642 shares of Zymeworks Inc.. This represents a change in shares of -2.49% during the quarter. The current value of the position is $24,636,770 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ZYMEWORKS COM 98985Y108 1,011,777 -25,865 -2.49 25,335 -7.27 0.0009
2026-02-13 2025-12-31 13F ZYMEWORKS COM 98985Y108 1,037,642 -43,547 -4.03 27,321 47.95 0.0009
2025-11-14 2025-09-30 13F ZYMEWORKS COM 98985Y108 1,081,189 -7,270 -0.67 18,467 35.18 0.0006
2025-08-14 2025-06-30 13F ZYMEWORKS COM 98985Y108 1,088,459 3,326 0.31 13,660 5.70 0.0005
2025-05-15 2025-03-31 13F ZYMEWORKS COM 98985Y108 1,085,133 172 0.02 12,924 -18.64 0.0005
2025-02-14 2024-12-31 13F ZYMEWORKS COM 98985Y108 1,084,961 -86,816 -7.41 15,884 8.01 0.0006
2024-11-14 2024-09-30 13F ZYMEWORKS COM 98985Y108 1,171,777 67,401 6.10 14,706 56.47 0.0006
2024-08-14 2024-06-30 13F ZYMEWORKS COM 98985Y108 1,104,376 55,644 5.31 9,398 -14.81 0.0004
2024-05-15 2024-03-31 13F ZYMEWORKS COM 98985Y108 1,048,732 40,920 4.06 11,033 5.36 0.0005
2024-02-14 2023-12-31 13F ZYMEWORKS COM 98985Y108 1,007,812 70,710 7.55 10,471 76.25 0.0005
2023-11-14 2023-09-30 13F ZYMEWORKS COM 98985Y108 937,102 30,777 3.40 5,941 -24.13 0.0003
2023-08-14 2023-06-30 13F ZYMEWORKS COM 98985Y108 906,325 753,308 492.30 7,831 466.16 0.0004
2023-05-15 2023-03-31 13F ZYMEWORKS COM 98985Y108 153,017 51,032 50.04 1,383 72.66 0.0001
2023-05-15 2022-12-31 13F/A-99 ZYMEWORKS DEL COM 98985Y108 101,985 101,985 802 0.0000
2023-05-15 2022-12-31 13F ZYMEWORKS DEL COM 98985Y108 101,985 101,985 802 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.