Zymeworks Inc.
US ˙ NasdaqGS ˙ US98985Y1082

SecurityZYME / Zymeworks Inc.
InstitutionRitholtz Wealth Management
Latest Disclosed Ownership24,243 shares
Latest Disclosed Value $ 607,045
Ritholtz Wealth Management reports 0.39% decrease in ownership of ZYME / Zymeworks Inc.

On April 20, 2026 - Ritholtz Wealth Management filed a 13F-HR form disclosing ownership of 24,243 shares of Zymeworks Inc. (US:ZYME) valued at $607,045 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 23, 2026 disclosing 24,338 shares of Zymeworks Inc.. This represents a change in shares of -0.39% during the quarter. The current value of the position is $582,802 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-20 2026-03-31 13F ZYMEWORKS COM 98985Y108 24,243 -95 -0.39 607 -5.16 0.0105
2026-01-23 2025-12-31 13F ZYMEWORKS COM 98985Y108 24,338 -384 -1.55 641 51.66 0.0117
2025-10-28 2025-09-30 13F ZYMEWORKS COM 98985Y108 24,722 -513 -2.03 422 33.54 0.0082
2025-07-28 2025-06-30 13F ZYMEWORKS COM 98985Y108 25,235 -35,259 -58.29 317 -56.11 0.0070
2025-04-17 2025-03-31 13F ZYMEWORKS COM 98985Y108 60,494 -13,972 -18.76 720 -33.94 0.0215
2025-01-15 2024-12-31 13F ZYMEWORKS COM 98985Y108 74,466 4,297 6.12 1,090 23.86 0.0320
2024-10-10 2024-09-30 13F ZYMEWORKS COM 98985Y108 70,169 24,136 52.43 881 125.06 0.0265
2024-08-01 2024-06-30 13F ZYMEWORKS COM 98985Y108 46,033 -34,846 -43.08 392 -54.00 0.0129
2024-04-24 2024-03-31 13F ZYMEWORKS COM 98985Y108 80,879 49,190 155.23 851 158.36 0.0293
2024-01-18 2023-12-31 13F ZYMEWORKS COM 98985Y108 31,689 31,689 329 0.0128
2023-10-13 2023-09-30 13F ZYMEWORKS COM 98985Y108 0 -22,308 -100.00 0 -100.00
2023-07-17 2023-06-30 13F ZYMEWORKS COM 98985Y108 22,308 22,308 193 0.0087
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.