Zymeworks Inc.
US ˙ NasdaqGS ˙ US98985Y1082

SecurityZYME / Zymeworks Inc.
InstitutionAssenagon Asset Management S.A.
Latest Disclosed Ownership727,986 shares
Latest Disclosed Value $ 18,228,769
Assenagon Asset Management S.A. reports 12.45% increase in ownership of ZYME / Zymeworks Inc.

On April 20, 2026 - Assenagon Asset Management S.A. filed a 13F-HR form disclosing ownership of 727,986 shares of Zymeworks Inc. (US:ZYME) valued at $18,228,769 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 9, 2026 disclosing 647,374 shares of Zymeworks Inc.. This represents a change in shares of 12.45% during the quarter. The current value of the position is $17,500,783 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-20 2026-03-31 13F ZYMEWORKS COM 98985Y108 727,986 80,612 12.45 18,229 6.94 0.0277
2026-01-09 2025-12-31 13F ZYMEWORKS COM 98985Y108 647,374 -679,400 -51.21 17,045 -24.78 0.0235
2025-10-07 2025-09-30 13F ZYMEWORKS COM 98985Y108 1,326,774 833,994 169.24 22,661 266.45 0.0310
2025-07-11 2025-06-30 13F ZYMEWORKS COM 98985Y108 492,780 -2,287 -0.46 6,184 4.88 0.0092
2025-04-15 2025-03-31 13F ZYMEWORKS COM 98985Y108 495,067 -147,184 -22.92 5,896 -37.29 0.0098
2025-01-14 2024-12-31 13F ZYMEWORKS COM 98985Y108 642,251 311,107 93.95 9,403 126.28 0.0152
2024-10-23 2024-09-30 13F ZYMEWORKS COM 98985Y108 331,144 331,144 4,156 0.0076
2024-07-18 2024-06-30 13F ZYMEWORKS COM 98985Y108 0 -166,549 -100.00 0 -100.00
2024-04-24 2024-03-31 13F ZYMEWORKS COM 98985Y108 166,549 166,549 1,752 0.0041
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.