Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionVontobel Holding Ltd.
Latest Disclosed Ownership83,380 shares
Latest Disclosed Value $ 37,232,504
Vontobel Holding Ltd. reports 20.81% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Vontobel Holding Ltd. filed a 13F-HR form disclosing ownership of 83,380 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $37,232,505 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 105,287 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -20.81% during the quarter. The current value of the position is $37,256,685 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 83,380 -21,907 -20.81 37,233 -22.00 0.0343
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 105,287 -5,355 -4.84 47,733 10.16 0.1503
2025-10-15 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 110,642 38,844 54.10 43,332 35.56 0.1309
2025-07-23 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 71,798 -3,008 -4.02 31,964 -11.86 0.1018
2025-04-28 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 74,806 -114,143 -60.41 36,267 -52.34 0.1322
2025-01-30 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 188,949 75,653 66.77 76,090 44.41 0.2604
2024-10-16 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 113,296 -45,534 -28.67 52,692 -29.22 0.1701
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 158,830 50,450 46.55 74,447 64.33 0.2418
2024-05-10 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 108,380 46,946 76.42 45,304 81.24 0.3622
2024-06-04 2023-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 61,434 -6,200 -9.17 24,997 6.28 0.2094
2024-01-30 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 92,606 -7,767 37,680 0.1892
2024-06-04 2023-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 67,634 -363 -0.53 23,519 -1.71 0.2172
2023-10-11 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 100,373 -378 34,904 0.1947
2024-06-04 2023-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 67,997 10,387 18.03 23,929 31.83 0.2099
2023-07-24 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 100,751 43,141 35,455 0.1881
2024-06-04 2023-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 57,610 -5,089 -8.12 18,151 1.31 0.1689
2023-04-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 76,932 14,233 24,239 0.1379
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 62,699 3,573 6.04 17,917 3.49 0.1808
2022-11-04 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 59,126 -13,662 -18.77 17,311 -15.17 0.2021
2022-07-27 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,788 -17,903 -19.74 20,406 -12.29 0.2206
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 90,691 -26,006 -22.29 23,264 -10.38 0.2011
2022-02-14 2021-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 116,697 18,953 19.39 25,959 46.40 0.2157
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 97,744 0 17,731 0.0673
2021-10-29 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 97,744 19,318 24.63 17,731 14.89 0.1564
2021-08-06 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 78,426 11,786 17.69 15,433 7.76 0.1333
2021-05-11 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 66,640 8,572 14.76 14,321 15.05 0.1062
2021-02-12 2020-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 58,068 58,068 12,448 0.0816
2021-02-12 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 58,068 12,448 0.0816
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.