Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionTrexquant Investment LP
Latest Disclosed Ownership15,171 shares
Latest Disclosed Value $ 6,774,458
Trexquant Investment LP reports 67.06% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Trexquant Investment LP filed a 13F-HR form disclosing ownership of 15,171 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $6,774,458 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 46,053 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -67.06% during the quarter. The current value of the position is $6,778,858 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,171 -30,882 -67.06 6,774 -67.55 0.0487
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 46,053 40,637 750.31 20,879 884.35 0.1861
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,416 5,416 2,121 0.0218
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -5,904 -100.00 0 -100.00
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,904 1,936 48.79 2,468 52.85 0.0492
2024-02-09 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,968 2,449 161.22 1,615 205.68 0.0363
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,519 1,519 528 0.0133
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -4,176 -100.00 0 -100.00
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,176 -48,044 -92.00 1,316 -91.28 0.0361
2023-02-13 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 52,220 23,040 78.96 15,080 78.48 0.4276
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 29,180 29,180 8,449 0.2971
2022-02-11 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -15,061 -100.00 0 -100.00
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 15,061 15,061 2,732 0.2171
2021-02-11 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -18,712 -100.00 0 -100.00
2020-11-06 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,712 8,206 78.11 5,092 66.95 0.3277
2020-08-07 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 10,506 -3,851 -26.82 3,050 -10.71 0.2118
2020-05-08 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 14,357 -13,134 -47.78 3,416 -43.25 0.2479
2020-02-12 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 27,491 9,262 50.81 6,019 94.92 0.3561
2020-02-18 2019-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 18,229 9,027 98.10 3,088 83.05 0.2667
2019-11-08 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,229 9,027 3,088 266,702.5955
2019-08-09 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,202 -14,745 -61.57 1,687 -61.70 0.1518
2019-05-13 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 23,947 23,947 4,405 0.3129
2019-02-13 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -6,646 -100.00 0 -100.00
2018-11-09 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,646 -22,733 -77.38 1,281 -74.34 0.0963
2018-08-07 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 29,379 5,101 21.01 4,993 26.18 0.3460
2018-05-03 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,278 24,278 3,957 0.2758
2018-02-08 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -5,664 -100.00 0 -100.00
2017-11-09 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,664 3,354 145.19 861 188.93 0.2169
2017-08-01 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,310 -14,290 -86.08 298 -83.58 0.0816
2017-05-08 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,600 13,100 374.29 1,815 603.49 0.2328
2017-02-10 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,500 3,500 258 0.0408
2016-08-10 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -11,500 -100.00 0 -100.00
2016-05-11 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 11,500 -6,300 -35.39 914 -59.20 0.1071
2016-02-10 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,800 17,800 0.00 2,240 0.1973
2015-11-02 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -20,000 -100.00 0 -100.00
2015-08-12 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 20,000 14,000 233.33 2,469 249.22 0.2772
2015-05-13 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,000 6,000 707 0.0722
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.