Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSpire Wealth Management
Latest Disclosed Ownership1,905 shares
Latest Disclosed Value $ 850,481
Spire Wealth Management reports 2.56% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On April 22, 2026 - Spire Wealth Management filed a 13F-HR form disclosing ownership of 1,905 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $850,659 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 14, 2026 disclosing 1,955 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -2.56% during the quarter. The current value of the position is $815,988 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-22 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,905 -50 -2.56 850 -4.06 0.0183
2026-01-14 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,955 -381 -16.31 886 -3.17 0.0297
2025-10-23 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,336 -8,962 -79.32 915 -81.35 0.0311
2025-08-04 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 11,298 -7,278 -39.18 4,906 -45.53 0.1762
2025-04-23 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,576 72 0.39 9,006 20.86 0.2883
2025-01-24 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,504 -219 -1.17 7,452 -14.43 0.2314
2024-10-15 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,723 -1,031 -5.22 8,708 -5.83 0.2936
2024-07-31 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 19,754 -301 -1.50 9,246 -53.94 0.3262
2024-04-24 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 20,055 -596 -2.89 20,075 123.50 0.3644
2024-02-06 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 20,651 4,274 26.10 8,983 57.74 0.2968
2023-11-08 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,377 -6,796 -29.33 5,695 -30.17 0.2168
2023-08-09 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,173 -1,591 -6.42 8,155 4.51 0.3011
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,764 3,664 17.36 7,802 129,933.33 0.3038
2023-02-03 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,100 -676 -3.10 6 -99.90 0.3428
2022-11-07 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,776 -5,276 -19.50 6,305 -17.29 0.3829
2022-07-22 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 27,052 -11,007 -28.92 7,623 -23.33 0.3141
2022-04-18 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 38,059 35,416 1,339.99 9,943 1,614.31 0.2662
2022-01-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,643 1,727 188.54 580 249.40 0.0129
2021-10-22 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 916 -450 -32.94 166 -39.64 0.0044
2021-07-26 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,366 -3,362 -71.11 275 -72.93 0.0074
2021-05-21 2021-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 4,728 4,728 1,016 0.0270
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.