Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionWealthspire Advisors, LLC
Latest Disclosed Ownership895 shares
Latest Disclosed Value $ 399,654
Wealthspire Advisors, LLC reports 50.96% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 1, 2026 - Wealthspire Advisors, LLC filed a 13F-HR form disclosing ownership of 895 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $399,653 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 1,825 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -50.96% during the quarter. The current value of the position is $395,357 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-01 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 895 -930 -50.96 400 -51.75 0.0031
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,825 1,382 311.96 827 378.03 0.0066
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 443 -438 -49.72 173 -55.87 0.0009
2025-08-11 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 881 151 20.68 392 11.05 0.0022
2025-05-09 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 -19 -2.54 354 17.28 0.0021
2025-02-04 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 749 -43 -5.43 302 -18.21 0.0030
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 792 159 25.12 368 24.32 0.0037
2024-08-08 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 633 -108 -14.57 297 -4.21 0.0038
2024-05-06 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 741 -228 -23.53 310 -21.57 0.0041
2024-02-07 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 969 310 47.04 394 72.05 0.0056
2023-11-06 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 659 -1 -0.15 229 -1.29 0.0038
2023-08-01 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 660 660 232 0.0038
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -833 -100.00 0 -100.00
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 833 833 241 0.0044
2021-08-13 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -2,714 -100.00 0 -100.00
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,714 -88 -3.14 583 -11.93 0.0138
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,802 794 39.54 662 21.25 0.0197
2020-11-16 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,008 117 6.19 546 -0.55 0.0325
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,891 -438 -18.81 549 -0.90 0.0382
2020-05-12 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,329 1,335 134.31 554 154.13 0.0232
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 994 994 218 0.0159
2019-05-07 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -220 -100.00 0 -100.00
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 220 220 36 0.0035
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.