Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSmartleaf Asset Management LLC
Latest Disclosed Ownership4,540 shares
Latest Disclosed Value $ 2,012,088
Smartleaf Asset Management LLC reports 13.93% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Smartleaf Asset Management LLC filed a 13F-HR form disclosing ownership of 4,540 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $2,027,292 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 3,985 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 13.93% during the quarter. The current value of the position is $2,005,500 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,540 555 13.93 2,012 11.28 0.0727
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,985 752 23.26 1,808 41.47 0.0685
2025-11-05 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,233 770 31.26 1,278 17.57 0.0791
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,463 -385 -13.52 1,087 -22.52 0.0958
2025-05-14 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,848 244 9.37 1,403 34.90 0.1354
2025-02-05 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,604 381 17.14 1,040 1.07 0.1060
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,223 563 33.92 1,029 31.25 0.1249
2024-10-08 2024-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,660 354 27.11 785 43.85 0.1286
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,660 354 785 0.1286
2024-10-07 2024-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,306 431 49.26 545 53.52 0.1054
2024-05-03 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,306 431 403 0.0971
2024-02-12 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 875 875 356 0.0952
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.