Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSilvercrest Asset Management Group Llc
Latest Disclosed Ownership16,358 shares
Latest Disclosed Value $ 7,304,501
Silvercrest Asset Management Group Llc reports 2.06% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Silvercrest Asset Management Group Llc filed a 13F-HR form disclosing ownership of 16,358 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $7,304,501 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 16,028 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 2.06% during the quarter. The current value of the position is $7,309,245 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 16,358 330 2.06 7,305 0.52 0.0528
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,028 -931 -5.49 7,266 9.41 0.0499
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 16,959 6 0.04 6,642 -12.00 0.0440
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,953 107 0.64 7,548 -7.59 0.0507
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,846 -502 -2.89 8,167 16.91 0.0585
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,348 3,410 24.47 6,986 7.78 0.0467
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,938 179 1.30 6,482 0.51 0.0441
2024-08-15 2024-06-30 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,759 0 0.00 6,449 12.14 0.0442
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 27,518 13,759 12,898 0.0442
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,759 -20 -0.15 5,751 2.59 0.0389
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,779 -473 -3.32 5,607 13.14 0.0397
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,252 250 1.79 4,956 0.57 0.0376
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,002 583 4.34 4,927 16.56 0.0351
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,419 -10 -0.07 4,228 9.00 0.0321
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,429 -49 -0.36 3,878 -0.62 0.0298
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,478 -40 -0.30 3,902 2.44 0.0321
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,518 -558 -3.96 3,809 3.70 0.0290
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,076 6 0.04 3,673 18.87 0.0239
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,070 0 0.00 3,090 21.08 0.0196
2021-11-15 2021-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,070 0 0.00 2,552 -10.05 0.0172
2021-08-16 2021-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,070 0 0.00 2,837 -6.18 0.0186
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,070 -666 -4.52 3,024 -13.18 0.0204
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,736 700 4.99 3,483 -8.80 0.0254
2020-11-16 2020-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,036 0 0.00 3,819 -6.28 0.0328
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,036 0 0.00 4,075 22.01 0.0361
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,036 619 4.61 3,340 13.68 0.0358
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,417 0 0.00 2,938 29.26 0.0228
2019-11-14 2019-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,417 0 0.00 2,273 -7.60 0.0187
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 13,417 1,793 15.42 2,460 15.06 0.0230
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 11,624 -49 -0.42 2,138 10.55 0.0210
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 11,673 49 0.42 1,934 -13.66 0.0213
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 11,624 55 0.48 2,240 13.94 0.0203
2018-08-14 2018-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 11,569 1,779 18.17 1,966 23.18 0.0184
2018-05-15 2018-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 9,790 -233 -2.32 1,596 6.26 0.0156
2018-02-14 2017-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 10,023 43 0.43 1,502 -0.99 0.0140
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 9,980 0 0.00 1,517 17.96 0.0151
2017-08-14 2017-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 9,980 3,291 49.20 1,286 75.92 0.0138
2017-05-15 2017-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,689 0 0.00 731 48.28 0.0078
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,689 0 0.00 493 -15.44 0.0055
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,689 0 0.00 583 1.39 0.0070
2016-08-15 2016-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,689 -150 -2.19 575 5.70 0.0073
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,839 0 0.00 544 -36.82 0.0075
2016-02-16 2015-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,839 -125 -1.79 861 18.76 0.0119
2015-11-16 2015-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,964 0 0.00 725 -15.70 0.0110
2015-08-14 2015-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,964 600 9.43 860 14.51 0.0115
2015-05-15 2015-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,364 -600 -8.62 751 -9.19 0.0107
2015-02-17 2014-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,964 750 12.07 827 18.48 0.0120
2014-11-14 2014-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,214 0 0.00 698 18.71 0.0108
2014-08-14 2014-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,214 -400 -6.05 588 25.64 0.0088
2014-05-15 2014-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,614 0 0.00 468 -4.68 0.0074
2014-02-14 2013-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,614 0 0.00 491 -2.00 0.0081
2013-11-14 2013-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,614 -10 -0.15 501 -5.47 0.0096
2013-08-14 2013-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 6,624 6,624 530 0.0112
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.