Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSigma Planning Corp
Latest Disclosed Ownership1,062 shares
Latest Disclosed Value $ 474,199
Sigma Planning Corp reports 37.01% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 4, 2026 - Sigma Planning Corp filed a 13F-HR form disclosing ownership of 1,062 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $474,225 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 30, 2026 disclosing 1,686 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -37.01% during the quarter. The current value of the position is $454,897 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-04 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,062 -624 -37.01 474 -37.96 0.0132
2026-01-30 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,686 54 3.31 764 19.56 0.0211
2025-11-10 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,632 -648 -28.42 639 -36.98 0.0182
2025-08-05 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,280 -34 -1.47 1,015 -9.55 0.0305
2025-05-02 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,314 -17 -0.73 1,122 19.51 0.0358
2025-02-03 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,331 -415 -15.11 939 -26.55 0.0295
2024-11-04 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,746 -261 -8.68 1,277 -9.37 0.0391
2024-08-06 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,007 14 0.47 1,409 12.63 0.0447
2024-05-02 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,993 1,212 68.05 1,251 72.79 0.0393
2024-02-01 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,781 -1,061 -37.33 724 -26.72 0.0567
2023-11-06 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,842 80 2.90 988 1.65 0.0370
2023-08-02 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,762 10 0.36 972 12.11 0.0349
2023-05-08 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,752 -412 -13.02 867 -5.04 0.0288
2023-01-24 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,164 44 1.41 914 1.11 0.0327
2022-11-10 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,120 1,082 53.09 903 57.32 0.0344
2022-08-11 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,038 535 35.60 574 46.43 0.0199
2022-04-20 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,503 -112 -6.93 392 10.42 0.0117
2022-02-02 2021-12-31 13F VERTEX PHARMACEUTICALS IN Stock 92532F100 1,615 -1,193 -42.49 355 -30.26 0.0099
2021-10-28 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,808 1,201 74.74 509 57.10 0.0153
2021-08-13 2021-06-30 13F VERTEX PHARMACEUTICALS IN Stock 92532F100 1,607 390 32.05 324 23.66 0.0097
2021-05-06 2021-03-31 13F VERTEX PHARMACEUTICALS IN Stock 92532F100 1,217 22 1.84 262 -7.09 0.0084
2021-02-09 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,195 1,195 282 0.0096
2020-11-03 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -9,006 -100.00 0 -100.00
2020-07-31 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,006 9,006 2,615 0.1148
2020-05-01 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -1,104 -100.00 0 -100.00
2020-02-03 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,104 1,104 242 0.0102
2015-04-23 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -8,483 -100.00 0 -100.00
2015-02-13 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,483 8,483 1,008 0.1333
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.