Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionShell Asset Management Co
Latest Disclosed Ownership6,666 shares
Latest Disclosed Value $ 2,611
Shell Asset Management Co reports 61.20% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On November 7, 2025 - Shell Asset Management Co filed a 13F-HR form disclosing ownership of 6,666 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $2,610,672 USD as of September 30, 2025. The entity filed a previous 13F-HR on July 23, 2025 disclosing 17,181 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -61.20% during the quarter. The current value of the position is $2,855,314 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2025-11-07 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,666 -10,515 -61.20 3 -71.43 0.2622
2025-07-23 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,181 3,809 28.48 8 16.67 0.2641
2025-05-14 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 13,372 -1,285 -8.77 6 20.00 0.3078
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 14,657 79 0.54 6 -16.67 0.2579
2024-11-07 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,578 -1,496 -9.31 7 -14.29 0.2984
2024-07-25 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,074 -77 -0.48 8 16.67 0.3430
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,151 -2,817 -14.85 7 0.00 0.3035
2023-11-08 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,968 -212 -1.11 7 0.00 0.2726
2023-07-28 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 19,180 919 5.03 7 20.00 0.2662
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,261 -41 -0.22 6 0.00 0.2387
2023-02-07 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,302 -5,523 -23.18 5 -99.93 0.2315
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,825 -5,375 -18.41 6,898 -16.16 0.2688
2022-08-09 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 29,200 -3,821 -11.57 8,228 -4.51 0.2434
2022-05-04 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 33,021 4,182 14.50 8,617 36.07 0.2034
2022-02-09 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 28,839 -8,012 -21.74 6,333 -5.25 0.1299
2021-11-04 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 36,851 -17,808 -32.58 6,684 -39.35 0.1501
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 54,659 -7,709 -12.36 11,021 -17.77 0.2137
2021-05-10 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 62,368 -14,921 -19.31 13,402 -26.63 0.2681
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 77,289 25,367 48.86 18,266 29.28 0.3772
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 51,922 -322 -0.62 14,129 -6.84 0.3285
2020-08-10 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 52,244 36,049 222.59 15,167 293.54 0.3786
2020-05-11 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,195 -1,811 -10.06 3,854 -2.23 0.1074
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,006 -507 -2.74 3,942 25.70 0.0849
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,513 -2,438 -11.64 3,136 -18.38 0.0716
2019-08-12 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 20,951 964 4.82 3,842 4.49 0.0850
2019-05-09 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 19,987 1,314 7.04 3,677 18.84 0.0811
2019-02-13 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,673 -5,060 -21.32 3,094 -32.36 0.0771
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,733 -1,067 -4.30 4,574 8.52 0.0903
2018-08-10 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 24,800 1,323 5.64 4,215 10.17 0.0864
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 23,477 -1,207 -4.89 3,826 3.43 0.0762
2018-02-09 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,684 3,142 14.59 3,699 12.95 0.0734
2017-10-20 2017-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 21,542 -6,363 -22.80 3,275 -8.93 0.0728
2017-10-18 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 46,453 18,548 5,217
2017-07-26 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 27,905 -1,614 -5.47 3,596 11.40 0.0892
2017-04-26 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 29,519 1,141 4.02 3,228 54.38 0.0824
2017-01-10 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 28,378 -1,297 -4.37 2,091 -19.20 0.0565
2016-10-28 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 29,675 -1,384 -4.46 2,588 -3.14 0.0619
2016-07-25 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 31,059 6,799 28.03 2,672 38.59 0.0620
2016-05-11 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,260 -174 -0.71 1,928 -37.30 0.0462
2016-02-05 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,434 -22,019 -47.40 3,075 -41.06 0.0726
2015-10-13 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 46,453 13,777 42.16 5,217 29.29 0.0827
2015-07-30 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 32,676 -7,017 -17.68 4,035 -13.84 0.0807
2015-05-07 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 39,693 39,693 0.00 4,683 0.0815
2015-02-04 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -46,453 -100.00 0 -100.00
2014-10-24 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 46,453 6,829 17.23 5,217 39.05 0.0810
2014-08-08 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 39,624 -228 -0.57 3,752 33.14 0.0578
2014-05-07 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 39,852 -3,419 -7.90 2,818 -12.35 0.0468
2014-02-03 2013-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 43,271 -22,574 -34.28 3,215 -35.60 0.0547
2014-01-27 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 43,271 3,215
2013-10-28 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 65,845 -332 -0.50 4,992 -5.78 0.0917
2013-08-01 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 66,177 66,177 5,298 0.1009
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.