Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSegall Bryant & Hamill, Llc
Latest Disclosed Ownership29,994 shares
Latest Disclosed Value $ 14,768,634
Segall Bryant & Hamill, Llc reports 24.67% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Segall Bryant & Hamill, Llc filed a 13F-HR form disclosing ownership of 29,994 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $13,393,521 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 39,819 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -24.67% during the quarter. The current value of the position is $13,402,219 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 29,994 -9,825 -24.67 14,769 -18.19 0.2393
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 39,819 -1,152 -2.81 18,052 12.51 0.2443
2025-11-12 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 40,971 -1,357 -3.21 16,046 -14.85 0.2138
2025-08-12 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 42,328 -10,494 -19.87 18,844 -26.42 0.2646
2025-05-02 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 52,822 -3,413 -6.07 25,609 13.09 0.3924
2025-02-11 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 56,235 -1,590 -2.75 22,646 -15.80 0.3116
2024-11-08 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 57,825 57,825 26,893 0.3667
2023-11-09 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -876 -100.00 0 -100.00
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 876 14 1.62 308 0.0032
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 862 0 0.00 0 -100.00 0.0029
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 862 0 0.00 248 -0.80 0.0028
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICA COM 92532F100 862 0 0.00 250 2.88 0.0030
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 862 0 0.00 243 8.00 0.0027
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 862 862 225 0.0022
2021-11-03 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -2,385 -100.00 0 -100.00
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,385 376 18.72 480 11.37 0.0047
2021-05-13 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,009 18 0.90 431 -8.10 0.0043
2021-02-12 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,991 174 9.58 469 -4.87 0.0052
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,817 946 108.61 493 94.86 0.0067
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 871 0 0.00 253 21.63 0.0043
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 871 871 208 0.0042
2019-02-14 2018-12-31 13F Vertex Pharmaceuticals COM 92532F100 0 -1,136 -100.00 0 -100.00
2018-11-14 2018-09-30 13F Vertex Pharmaceuticals COM 92532F100 1,136 1,136 219 0.0032
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.