Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSchroder Investment Management Group
Latest Disclosed Ownership163,898 shares
Latest Disclosed Value $ 72,633,037
Schroder Investment Management Group reports 32.98% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 14, 2026 - Schroder Investment Management Group filed a 13F-HR form disclosing ownership of 163,898 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $73,187,013 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 123,252 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 32.98% during the quarter. The current value of the position is $73,234,543 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 163,898 40,646 32.98 72,633 29.88 0.0596
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 123,252 1,665 1.37 55,924 16.35 0.0424
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 121,587 -13,380 -9.91 48,065 -20.01 0.0376
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 134,967 -14,420 -9.65 60,087 -18.36 0.0508
2025-05-13 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 149,387 -14,241 -8.70 73,601 12.64 0.0743
2025-02-12 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 163,628 -42,151 -20.48 65,345 -31.40 0.0626
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 205,779 -23,040 -10.07 95,251 -11.19 0.0976
2024-08-12 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 228,819 20,531 9.86 107,252 23.18 0.1183
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 208,288 -24,692 -10.60 87,066 -8.16 0.1024
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 232,980 39,712 20.55 94,797 41.05 0.1229
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 193,268 -1,684 -0.86 67,207 -2.04 0.1000
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 194,952 16,657 9.34 68,606 22.13 0.0984
2023-05-11 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 178,295 -21,566 -10.79 56,175 -2.67 0.0836
2023-02-10 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 199,861 90,908 83.44 57,716 82.95 0.0916
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 108,953 54,563 100.32 31,547 106.89 0.0522
2022-08-11 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 54,390 -6,863 -11.20 15,248 -2.95 0.0232
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 61,253 15,359 33.47 15,712 55.89 0.0208
2022-02-14 2021-12-31 13F Vertex Pharmaceuticals COM 92532F100 45,894 -1,285 -2.72 10,079 17.79 0.0132
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 47,179 2,891 6.53 8,557 -4.18 0.0132
2021-08-13 2021-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 44,288 18,328 70.60 8,930 60.06 0.0112
2021-05-28 2021-03-31 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,960 401 1.57 5,579 92,883.33 0.0072
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,960 401 5,579 0.0072
2021-02-24 2020-12-31 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,559 -1,493 -5.52 6 -99.91 0.0085
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,559 -1,493 6 0.0084
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 27,052 -54,791 -66.95 7,055 -70.31 0.0113
2020-08-13 2020-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 81,843 71,250 672.61 23,761 778.74 0.0431
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 10,593 -1,456 -12.08 2,704 2.50 0.0058
2020-02-11 2019-12-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 12,049 -38,880 -76.34 2,638 -68.94 0.0043
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 50,929 46,382 1,020.06 8,492 918.23 0.0150
2019-11-14 2019-06-30 13F/A-2 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 4,547 -29,775 -86.75 834 -86.79 0.0015
2019-08-15 2019-06-30 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 4,547 0 834 0.0009
2019-08-08 2019-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 4,547 -29,775 834 894.7582
2019-11-15 2019-03-31 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 34,322 -51 -0.15 6,314 10.85 0.0112
2019-05-14 2019-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 34,322 -51 6,314 10,255.2358
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 34,373 738 2.19 5,696 -12.14 0.0103
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 33,635 6,326 23.16 6,483 60.83 0.0111
2018-08-23 2018-06-30 13F/A-2 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 27,309 1,849 7.26 4,031 -2.84 0.0071
2018-08-16 2018-06-30 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 27,309 0 4,031 0.0071
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 27,309 1,849 4,031 7,137.7723
2018-05-11 2018-03-31 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,460 1,300 5.38 4,149 14.58 0.0072
2018-05-11 2018-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 25,460 1,300 4,149 7,189.8784
2018-02-09 2017-12-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 24,160 0 0.00 3,621 0.17 0.0059
2017-11-09 2017-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 24,160 -9,238 -27.66 3,615 -14.94 0.0063
2017-08-10 2017-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 33,398 2,478 8.01 4,250 28.13 0.0077
2017-05-18 2017-03-31 13F/A-1 VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 30,920 30,920 3,317 0.0060
2017-05-10 2017-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 30,920 30,920 3,317 5,962.2872
2016-11-09 2016-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 0 -5,677 -100.00 0 -100.00
2016-08-08 2016-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 5,677 -5,900 -50.96 488 -46.26 0.0010
2016-05-10 2016-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 11,577 -7,800 -40.25 908 -62.76 0.0019
2016-02-10 2015-12-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 19,377 -17,600 -47.60 2,438 -36.69 0.0050
2015-11-13 2015-09-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 36,977 25,400 219.40 3,851 172.54 0.0081
2015-08-10 2015-06-30 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 11,577 0 0.00 1,413 1.44 0.0028
2015-05-12 2015-03-31 13F VERTEX PHARMACEUTICALS INCORPORATED USD0.01 COM 92532F100 11,577 11,577 27.08 1,393 -99.80 0.0027
2014-02-14 2013-12-31 13F Vertex Pharma Comm Stk USD0.01 COM 92532F100 0 -9,110 -100.00 0 -100.00
2013-12-09 2013-09-30 13F/A-1 Vertex Pharma Comm Stk USD0.01 COM 92532F100 690,720 681,610 52,370 0.0016
2013-12-10 2013-09-30 13F/A-2 Vertex Pharma Comm Stk USD0.01 COM 92532F100 9,110 0 0.00 691 -5.35 0.0017
2013-11-08 2013-09-30 13F Vertex Pharma Comm Stk USD0.01 COM 92532F100 9,110 0 691 1.7044
2013-08-12 2013-06-30 13F Vertex Pharma Comm Stk USD0.01 COM 92532F100 9,110 9,110 729 0.0019
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.