Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionRMB Capital Management, LLC
Latest Disclosed Ownership899 shares
Latest Disclosed Value $ 401,494
RMB Capital Management, LLC reports 9.28% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - RMB Capital Management, LLC filed a 13F-HR form disclosing ownership of 899 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $401,439 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 991 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -9.28% during the quarter. The current value of the position is $401,700 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 899 -92 -9.28 401 -10.69 0.0054
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 991 -79 -7.38 449 7.16 0.0078
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,070 -186 -14.81 419 -25.04 0.0077
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,256 835 198.34 559 174.02 0.0106
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 421 -1,289 -75.38 204 -70.35 0.0050
2025-02-13 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,710 130 8.23 689 -6.27 0.0159
2024-11-06 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,580 71 4.71 735 3.82 0.0167
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,509 319 26.81 707 42.25 0.0170
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,190 11 0.93 497 3.76 0.0114
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,179 56 4.99 480 22.82 0.0146
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,123 117 11.63 391 10.17 0.0134
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,006 11 1.11 354 13.10 0.0116
2023-05-11 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 995 0 0.00 313 9.06 0.0110
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 995 995 287 0.0102
2021-02-11 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -1,167 -100.00 0 -100.00
2020-11-10 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,167 -212 -15.37 318 -20.50 0.0138
2020-08-05 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,379 176 14.63 400 39.86 0.0176
2020-05-11 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,203 -7,994 -86.92 286 -85.80 0.0136
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,197 1,610 21.22 2,014 56.73 0.0560
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,587 -6,685 -46.84 1,285 -50.90 0.0338
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,272 -831 -5.50 2,617 -5.80 0.0662
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,103 -6,010 -28.47 2,778 -20.61 0.0702
2019-02-13 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,113 617 3.01 3,499 -11.42 0.0893
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 20,496 5,032 32.54 3,950 50.30 0.0948
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 15,464 -6,308 -28.97 2,628 -25.93 0.0625
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,772 21,772 3,548 0.0908
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.