Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionPrudent Man Advisors, LLC
Latest Disclosed Ownership3,427 shares
Latest Disclosed Value $ 1,530,293
Prudent Man Advisors, LLC reports 60.97% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Prudent Man Advisors, LLC filed a 13F-HR form disclosing ownership of 3,427 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,530,293 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 11, 2026 disclosing 2,129 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 60.97% during the quarter. The current value of the position is $1,531,286 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,427 1,298 60.97 1,530 58.55 0.4583
2026-02-11 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,129 578 37.27 965 58.98 0.3514
2026-02-11 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,129 965
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,551 -184 -10.61 607 -21.37 0.2238
2025-07-31 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,735 376 27.67 772 17.33 0.2453
2025-05-01 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,359 -403 -22.87 659 -7.19 0.2392
2025-02-05 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,762 -122 -6.48 710 -19.06 0.2578
2024-11-07 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,884 -124 -6.18 876 -6.91 0.2923
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,008 74 3.83 941 16.46 0.3327
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,934 -123 -5.98 808 -3.35 0.3032
2024-02-13 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,057 -30 -1.44 837 15.31 0.3123
2023-11-09 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,087 -71 -3.29 726 0.2879
2023-08-10 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,158 -30 -1.37 1 0.2853
2023-05-05 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,188 -25 -1.13 1 0.2693
2023-02-13 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,213 588 36.18 1 -100.00 0.2582
2022-11-09 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,625 -12 -0.73 471 2.17 0.2231
2022-08-05 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,637 -28 -1.68 461 5.98 0.2151
2022-05-09 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,665 -59 -3.42 435 14.78 0.1763
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICA COM 92532F100 1,724 -3 -0.17 379 21.09 0.1442
2021-11-10 2021-09-30 13F VERTEX PHARMACEUTICA COM 92532F100 1,727 -21 -1.20 313 -11.08 0.1184
2021-08-03 2021-06-30 13F VERTEX PHARMACEUTICA COM 92532F100 1,748 53 3.13 352 -3.30 0.1359
2021-05-14 2021-03-31 13F VERTEX PHARMACEUTICA COM 92532F100 1,695 83 5.15 364 -4.46 0.1529
2021-02-11 2020-12-31 13F VERTEX PHARMACEUTICA Common Stock 92532F100 1,612 -31 -1.89 381 -14.77 0.1596
2020-11-16 2020-09-30 13F/A-1 VERTEX PHARMACEUTICA COM Common Stock 92532F100 1,643 54 3.40 447 -3.04 0.2370
2020-11-12 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,589 0 461 388,917.9476
2020-08-12 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,589 1,589 461 0.4091
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.