Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionPnc Financial Services Group, Inc.
Latest Disclosed Ownership71,942 shares
Latest Disclosed Value $ 32,124,981
Pnc Financial Services Group, Inc. reports 3.63% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Pnc Financial Services Group, Inc. filed a 13F-HR form disclosing ownership of 71,942 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $32,124,981 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 69,425 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 3.63% during the quarter. The current value of the position is $32,145,844 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 71,942 2,517 3.63 32,125 2.07 0.0031
2026-02-06 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 69,425 -347 -0.50 31,475 15.18 0.0172
2025-11-07 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 69,772 -6,384 -8.38 27,326 -19.40 0.0166
2025-08-08 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 76,156 -2,005 -2.57 33,905 -10.53 0.0218
2025-05-09 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 78,161 -461 -0.59 37,894 19.69 0.0198
2025-02-07 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 78,622 -807 -1.02 31,661 -14.29 0.0212
2024-11-08 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 79,429 4,269 5.68 36,941 4.86 0.0236
2024-08-09 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 75,160 -4,794 -6.00 35,229 5.41 0.0235
2024-05-10 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 79,954 3,258 4.25 33,422 7.10 0.0232
2024-03-22 2023-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 76,696 2,431 3.27 31,207 20.84 0.0245
2024-02-09 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 76,696 2,431 31,207 0.0245
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 74,265 1,573 2.16 25,825 0.95 0.0221
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,692 4,480 6.57 25,581 19.03 0.0218
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 68,212 -2,063 -2.94 21,492 5.90 0.0189
2023-02-10 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 70,275 -2,328 -3.21 20,294 -3.46 0.0195
2022-11-10 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,603 1,248 1.75 21,022 4.56 0.0220
2022-08-12 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 71,355 191 0.27 20,105 8.26 0.0197
2022-05-12 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 71,164 19,627 38.08 18,571 64.10 0.0163
2022-02-11 2021-12-31 13F VERTEX PHA Common Stock 92532F100 51,537 20,397 65.50 11,317 100.34 0.0094
2021-11-05 2021-09-30 13F VERTEX PHA Common Stock 92532F100 31,140 1,524 5.15 5,649 -5.41 0.0052
2021-08-06 2021-06-30 13F VERTEX PHA Common Stock 92532F100 29,616 -110 -0.37 5,972 -6.50 0.0054
2021-05-07 2021-03-31 13F VERTEX PHA Common Stock 92532F100 29,726 -15,956 -34.93 6,387 -40.84 0.0062
2021-02-12 2020-12-31 13F VERTEX PHA Common Stock 92532F100 45,682 -1,789 -3.77 10,796 -16.43 0.0109
2020-11-06 2020-09-30 13F VERTEX PHA Common Stock 92532F100 47,471 1,575 3.43 12,919 -3.04 0.0159
2020-08-28 2020-06-30 13F/A-1 VERTEX PHA Common Stock 92532F100 45,896 21,649 89.29 13,324 130.92 0.0177
2020-08-07 2020-06-30 13F VERTEX PHA Common Stock 92532F100 45,896 21,649 13,324 2,766.5741
2020-05-08 2020-03-31 13F VERTEX PHA Common Stock 92532F100 24,247 857 3.66 5,770 12.67 0.0073
2020-02-07 2019-12-31 13F VERTEX PHA Common Stock 92532F100 23,390 33 0.14 5,121 29.38 0.0050
2019-11-08 2019-09-30 13F VERTEX PHA Common Stock 92532F100 23,357 -1,636 -6.55 3,958 -13.64 0.0039
2019-08-09 2019-06-30 13F VERTEX PHA Common Stock 92532F100 24,993 -1,042 -4.00 4,583 -4.32 0.0045
2019-05-10 2019-03-31 13F VERTEX PHA Common Stock 92532F100 26,035 1,200 4.83 4,790 16.40 0.0048
2019-02-08 2018-12-31 13F VERTEX PHA Common Stock 92532F100 24,835 -6,915 -21.78 4,115 -32.76 0.0046
2018-11-09 2018-09-30 13F VERTEX PHA Common Stock 92532F100 31,750 8,707 37.79 6,120 56.20 0.0058
2018-08-10 2018-06-30 13F VERTEX PHA Common Stock 92532F100 23,043 -1,825 -7.34 3,918 -3.33 0.0039
2018-05-11 2018-03-31 13F VERTEX PHA Common Stock 92532F100 24,868 1,108 4.66 4,053 13.88 0.0040
2018-02-09 2017-12-31 13F VERTEX PHA Common Stock 92532F100 23,760 -2,145 -8.28 3,559 -9.60 0.0035
2017-11-13 2017-09-30 13F VERTEX PHA Common Stock 92532F100 25,905 3,419 15.21 3,937 35.85 0.0041
2017-08-11 2017-06-30 13F VERTEX PHA 92532F100 22,486 1,486 7.08 2,898 26.16 0.0031
2017-05-12 2017-03-31 13F VERTEX PHA Common Stock 92532F100 21,000 3,527 20.19 2,297 78.34 0.0025
2017-02-10 2016-12-31 13F VERTEX PHA Common Stock 92532F100 17,473 -6,660 -27.60 1,288 -38.78 0.0015
2016-11-04 2016-09-30 13F VERTEX PHA Common Stock 92532F100 24,133 3,069 14.57 2,104 16.05 0.0024
2016-08-05 2016-06-30 13F VERTEX PHA Common Stock 92532F100 21,064 4,179 24.75 1,813 35.10 0.0021
2016-05-06 2016-03-31 13F VERTEX PHA Common Stock 92532F100 16,885 3,182 23.22 1,342 -22.25 0.0016
2016-02-05 2015-12-31 13F VERTEX PHA Common Stock 92532F100 13,703 -22,583 -62.24 1,726 -54.30 0.0020
2015-11-06 2015-09-30 13F VERTEX PHA Common Stock 92532F100 36,286 1,039 2.95 3,777 -13.21 0.0045
2015-08-05 2015-06-30 13F VERTEX PHA Common Stock 92532F100 35,247 -825 -2.29 4,352 2.26 0.0049
2015-05-08 2015-03-31 13F VERTEX PHA Common Stock 92532F100 36,072 2,061 6.06 4,256 5.35 0.0047
2015-02-06 2014-12-31 13F/A-1 VERTEX PHA Common Stock 92532F100 34,011 5,988 21.37 4,040 28.38 0.0044
2015-02-06 2014-12-31 13F VERTEX PHA Common Stock 92532F100 34,011 4,040
2014-11-07 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 28,023 13,111 87.92 3,147 122.88 0.0037
2014-08-08 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,912 -430 -2.80 1,412 30.14 0.0018
2014-05-09 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,342 -2,329 -13.18 1,085 -17.43 0.0014
2014-02-07 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,671 -3,309 -15.77 1,314 -17.46 0.0017
2013-11-01 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 20,980 2,838 15.64 1,592 9.64 0.0023
2013-08-02 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,142 18,142 1,452 0.0021
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.