Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionPathstone Holdings, LLC
Latest Disclosed Ownership44,262 shares
Latest Disclosed Value $ 19,765,162
Pathstone Holdings, LLC reports 2.94% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 11, 2026 - Pathstone Holdings, LLC filed a 13F-HR form disclosing ownership of 44,262 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $19,764,753 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 45,604 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -2.94% during the quarter. The current value of the position is $19,552,296 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-11 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 44,262 -1,342 -2.94 19,765 -4.40 0.0425
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 45,604 7,725 20.39 20,675 39.37 0.0797
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 37,879 1,446 3.97 14,835 -8.54 0.0567
2025-08-12 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 36,433 -1,441 -3.80 16,220 -11.65 0.0641
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,874 521 1.39 18,358 22.04 0.0796
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,353 -3,300 -8.12 15,043 -20.44 0.0665
2024-11-07 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 40,653 2,112 5.48 18,907 4.66 0.0836
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 38,541 1,538 4.16 18,065 16.80 0.0815
2024-05-13 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,003 4,472 13.75 15,468 16.78 0.0721
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 32,531 32,531 13,245 0.0711
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.