Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionPanagora Asset Management Inc
Latest Disclosed Ownership3,408 shares
Latest Disclosed Value $ 1,521,808
Panagora Asset Management Inc reports 2.21% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 14, 2026 - Panagora Asset Management Inc filed a 13F-HR form disclosing ownership of 3,408 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,521,808 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 3,485 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -2.21% during the quarter. The current value of the position is $1,522,797 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,408 -77 -2.21 1,522 -3.67 0.0057
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,485 77 2.26 1,580 18.37 0.0056
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,408 0 0.00 1,335 -12.06 0.0054
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,408 -11 -0.32 1,517 -8.45 0.0068
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,419 -6 -0.18 1,658 20.16 0.0083
2025-02-13 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,425 -9,910 -74.32 1,379 -77.76 0.0064
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,335 -35,219 -72.54 6,202 -72.75 0.0296
2024-07-29 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 48,554 -51,616 -51.53 22,758 -45.65 0.1144
2024-05-07 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 100,170 -133,961 -57.22 41,872 -56.05 0.2183
2024-02-08 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 234,131 32,612 16.18 95,266 35.95 0.5329
2023-10-31 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 201,519 105,608 110.11 70,076 107.62 0.4352
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 95,911 60,495 170.81 33,752 202.49 0.1988
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 35,416 -75,526 -68.08 11,159 -65.17 0.0705
2023-02-13 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 110,942 34,885 45.87 32,038 45.48 0.2101
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 76,057 -22 -0.03 22,022 2.72 0.1527
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 76,079 -108,918 -58.88 21,438 -55.60 0.1405
2022-05-12 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 184,997 -89,263 -32.55 48,279 -19.84 0.2629
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 274,260 -115,628 -29.66 60,227 -14.84 0.3189
2021-11-10 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 389,888 90,980 30.44 70,722 17.34 0.3779
2021-08-11 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 298,908 71,477 31.43 60,269 23.32 0.3229
2021-05-12 2021-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 227,431 185,337 440.29 48,873 391.28 0.2744
2021-02-10 2020-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 42,094 -49,947 -54.27 9,948 -60.28 0.0589
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 92,041 14,368 18.50 25,046 11.07 0.1569
2020-08-12 2020-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 77,673 97 0.13 22,549 22.16 0.1437
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 77,576 -553 -0.71 18,459 7.91 0.1306
2020-02-12 2019-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 78,129 -182,691 -70.04 17,106 -61.29 0.0777
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 260,820 -478,708 -64.73 44,188 -67.42 0.2038
2019-08-09 2019-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 739,528 -116,764 -13.64 135,615 -13.90 0.6065
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 856,292 -479,597 -35.90 157,515 -28.85 0.7003
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 1,335,889 -118,675 -8.16 221,370 -21.04 1.0304
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 1,454,564 499,019 52.22 280,353 72.63 1.0551
2018-08-14 2018-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 955,545 73,360 8.32 162,404 12.95 0.6439
2018-05-15 2018-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 882,185 61,554 7.50 143,779 16.91 0.5672
2018-02-14 2017-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 820,631 62,303 8.22 122,980 6.66 0.4614
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 758,328 145,142 23.67 115,296 45.91 0.4565
2017-08-14 2017-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 613,186 163,633 36.40 79,021 60.75 0.3180
2017-05-15 2017-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 449,553 -447 -0.10 49,159 48.28 0.2047
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 450,000 18,064 4.18 33,152 -11.99 0.1519
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 431,936 -4,337 -0.99 37,669 0.38 0.1796
2016-08-15 2016-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 436,273 -12,639 -2.82 37,528 5.17 0.1863
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 448,912 -6,766 -1.48 35,684 -37.77 0.1771
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 455,678 -184 -0.04 57,338 20.78 0.2825
2015-11-13 2015-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 455,862 44,757 10.89 47,473 -6.48 0.2506
2015-08-14 2015-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 411,105 28,519 7.45 50,763 12.47 0.2545
2015-05-15 2015-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 382,586 33,919 9.73 45,134 8.96 0.2291
2015-02-13 2014-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 348,667 121,717 53.63 41,422 62.51 0.2119
2014-11-12 2014-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 226,950 199,610 730.10 25,489 884.51 0.1235
2014-08-14 2014-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 27,340 -6,397 -18.96 2,589 8.51 0.0126
2014-05-15 2014-03-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 33,737 13,109 63.55 2,386 55.64 0.0113
2014-02-21 2013-12-31 13F VERTEX PHARMACEUTICALS COMMON 92532F100 20,628 3,803 22.60 1,533 20.14 0.0071
2013-11-14 2013-09-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 16,825 -12,306 -42.24 1,276 -45.17 0.0063
2013-08-14 2013-06-30 13F VERTEX PHARMACEUTICALS COMMON 92532F100 29,131 29,131 2,327 0.0119
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.