Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionNational Pension Service
Latest Disclosed Ownership532,069 shares
Latest Disclosed Value $ 237,590,091
National Pension Service reports 0.23% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 12, 2026 - National Pension Service filed a 13F-HR form disclosing ownership of 532,069 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $237,590,091 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 10, 2026 disclosing 530,841 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.23% during the quarter. The current value of the position is $237,744,391 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-12 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 532,069 1,228 0.23 237,590 -1.28 0.1804
2026-02-10 2025-12-31 13F VERTEX PHARMACEUTICALS VERTEX PHARMACEUTICALS INC 92532F100 530,841 18,728 3.66 240,662 19.99 0.1782
2025-11-04 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 512,113 14,313 2.88 200,564 -9.50 0.1558
2025-08-08 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 497,800 -61,129 -10.94 221,621 -18.22 0.1913
2025-05-13 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 558,929 31,455 5.96 270,980 27.57 0.2605
2025-02-05 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 527,474 16,427 3.21 212,414 -10.63 0.2010
2024-10-30 2024-09-30 13F VERTEXPHARMACEUTICALSINC COM 92532F100 511,047 49,402 10.70 237,678 9.84 0.2292
2024-08-13 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 461,645 7,109 1.56 216,382 13.89 0.2486
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 454,536 3,915 0.87 190,001 3.63 0.2280
2024-02-07 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 450,621 9,128 2.07 183,353 18.09 0.2553
2023-11-15 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 441,493 8,959 2.07 155,269 3.10 0.2485
2023-08-16 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 432,534 -44,321 -9.29 150,600 1.17 0.2429
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 476,855 60,763 14.60 148,855 23.88 0.2710
2023-02-24 2022-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 416,092 10,232 2.52 120,159 1.11 0.2364
2023-02-21 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 416,092 10,232 120 0.2364
2023-02-24 2022-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 405,860 3,493 0.87 118,836 4.81 0.2480
2022-11-18 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 405,860 3,493 118,836 0.2480
2022-08-17 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 402,367 31,483 8.49 113,383 17.14 0.2337
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 370,884 -9,006 -2.37 96,790 16.02 0.1767
2022-02-15 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 379,890 8,944 2.41 83,424 23.98 0.1455
2021-11-18 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 370,946 -1,100 -0.30 67,286 -10.30 0.1281
2021-08-17 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 372,046 4,914 1.34 75,016 -4.91 0.1425
2021-05-14 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 367,132 13,039 3.68 78,893 -5.73 0.1650
2021-02-19 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 354,093 21,917 6.60 83,686 -5.90 0.1908
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 332,176 0 0.00 88,933 -7.78 0.2336
2020-08-11 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 332,176 -2,190 -0.65 96,434 21.21 0.2754
2020-05-27 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 334,366 4,461 1.35 79,562 10.15 0.2693
2020-02-21 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 329,905 34,113 11.53 72,233 44.14 0.1982
2019-11-15 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 295,792 14,371 5.11 50,113 -2.89 0.1586
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 281,421 132 0.05 51,607 -0.26 0.1725
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 281,289 10,108 3.73 51,743 2.74 0.1990
2019-02-15 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 271,181 11,565 4.45 50,364 0.65 0.2078
2018-11-15 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 259,616 12,561 5.08 50,038 37.23 0.2037
2018-08-14 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 247,055 19,936 8.78 36,463 -1.49 0.1650
2018-04-13 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 227,119 7,392 3.36 37,016 12.41 0.1835
2018-01-17 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 219,727 -9,319 -4.07 32,928 -3.92 0.1644
2017-10-16 2017-09-30 13F Vertex Pharmaceuticals COM 92532F100 229,046 8,939 4.06 34,270 22.37 0.1886
2017-07-13 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 220,107 19,328 9.63 28,006 30.01 0.1668
2017-04-11 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 200,779 7,809 4.05 21,542 51.53 0.1442
2017-01-18 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 192,970 12,992 7.22 14,216 -9.43 0.0972
2016-10-14 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 179,978 14,697 8.89 15,696 10.40 0.1258
2016-08-11 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 165,281 32,142 24.14 14,217 34.34 0.1262
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 133,139 5,359 4.19 10,583 -34.18 0.1060
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 127,780 8,007 6.69 16,079 28.91 0.1689
2015-10-15 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 119,773 21,318 21.65 12,473 2.60 0.1577
2015-07-15 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 98,455 10,319 11.71 12,157 16.93 0.1577
2015-04-15 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 88,136 12,590 16.67 10,397 15.84 0.1502
2015-01-13 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 75,546 -10,161 -11.86 8,975 -6.76 0.1515
2014-11-07 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 85,707 85,707 9,626 0.1528
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.