Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionMassmutual Trust Co Fsb/adv
Latest Disclosed Ownership28,726 shares
Latest Disclosed Value $ 12,827,308
Massmutual Trust Co Fsb/adv reports 2.91% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On April 13, 2026 - Massmutual Trust Co Fsb/adv filed a 13F-HR form disclosing ownership of 28,726 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $12,827,308 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 7, 2026 disclosing 27,914 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 2.91% during the quarter. The current value of the position is $12,835,639 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-13 2026-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 28,726 812 2.91 12,827 1.36 0.3493
2026-01-07 2025-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 27,914 -581 -2.04 12,655 13.41 0.3257
2025-10-22 2025-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 28,495 1,704 6.36 11,160 -6.44 0.2843
2025-07-09 2025-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 26,791 9,775 57.45 11,927 44.59 0.3178
2025-04-01 2025-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 17,016 10,774 172.60 8,250 228.25 0.2386
2025-01-16 2024-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 6,242 3,641 139.98 2,514 107.86 0.0705
2024-10-02 2024-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 2,601 1,607 161.67 1,210 160.00 0.0345
2024-07-02 2024-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 994 131 15.18 466 29.17 0.0141
2024-04-09 2024-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 863 175 25.44 361 29.03 0.0112
2024-01-03 2023-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 688 36 5.52 280 23.45 0.0094
2023-10-04 2023-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 652 61 10.32 227 9.18 0.0084
2023-08-02 2023-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 591 206 53.51 208 71.07 0.0075
2023-04-11 2023-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 385 126 48.65 121 0.0046
2023-01-06 2022-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 259 4 1.57 0 0.0031
2022-10-07 2022-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 255 -21 -7.61 0 0.0034
2022-07-07 2022-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 276 20 7.81 0 0.0034
2022-04-08 2022-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 256 -38 -12.93 0 0.0025
2022-02-09 2021-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 294 -151 -33.93 0 0.0024
2021-11-12 2021-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 445 27 6.46 0 0.0033
2021-08-16 2021-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 418 -30 -6.70 0 0.0036
2021-05-17 2021-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 448 -483 -51.88 0 0.0045
2021-02-16 2020-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 931 -384 -29.20 0 0.0113
2020-11-13 2020-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 1,315 -11,029 -89.35 0 -100.00 0.0209
2020-08-13 2020-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 12,344 -2,004 -13.97 3,584 4.98 0.2310
2020-05-15 2020-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 14,348 186 1.31 3,414 10.09 0.2726
2020-05-15 2019-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 14,162 -206 -1.43 3,101 27.40 0.1915
2019-11-14 2019-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 14,368 580 4.21 2,434 -3.72 0.1630
2019-08-14 2019-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 13,788 1,272 10.16 2,528 9.82 0.1748
2019-05-15 2019-03-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 12,516 1,664 15.33 2,302 28.03 0.1660
2019-02-26 2018-12-31 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 10,852 10,852 1,798 0.1539
2018-11-09 2018-09-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 0 -14 -100.00 0 -100.00
2018-08-20 2018-06-30 13F Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 14 -86 -86.00 2 -85.71 0.0002
2018-03-01 2017-12-31 13F/A-1 Vertex Pharmaceuticals Common / Ordinary Stock 92532F100 100 -12 -10.71 15 -17.65 0.0012
2018-02-13 2017-09-30 13F Vertex Pharmaceuticals common 92532F100 112 12 12.00 17 41.67 0.0014
2017-08-14 2017-06-30 13F Vertex Pharmaceuticals common 92532F100 100 0 0.00 13 20.00 0.0011
2017-05-02 2017-03-31 13F Vertex Pharmaceuticals common 92532F100 100 -7 -6.54 11 42.86 0.0010
2017-02-13 2016-12-31 13F Vertex Pharmaceuticals common 92532F100 107 -25 -18.94 8 -36.36 0.0010
2016-08-10 2016-06-30 13F VERTEX PHARMACEUTICALS common 92532F100 132 7 5.60 11 22.22 0.0014
2016-05-10 2016-03-31 13F VERTEX PHARMACEUTICALS common 92532F100 125 -23 -15.54 10 -50.00 0.0013
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS common 92532F100 148 148 19 0.0027
2015-11-04 2015-09-30 13F VERTEX PHARMACEUTICALS common 92532F100 0 0 0 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.