Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionLittle House Capital Llc
Latest Disclosed Ownership8,961 shares
Latest Disclosed Value $ 4,001,445
Little House Capital Llc reports 0.25% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 7, 2026 - Little House Capital Llc filed a 13F-HR form disclosing ownership of 8,961 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $4,001,445 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 8,939 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.25% during the quarter. The current value of the position is $4,004,044 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,961 22 0.25 4,001 -1.26 1.0330
2026-02-06 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,939 -821 -8.41 4,053 6.02 1.0172
2025-11-03 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,760 3,930 67.41 3,822 47.28 0.8787
2025-07-08 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,830 -477 -7.56 2,596 -15.11 0.6501
2025-04-25 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,307 1,573 33.23 3,058 60.39 0.8404
2025-01-30 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,734 1,011 27.16 1,906 10.11 0.5447
2024-10-21 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,723 1,033 38.40 1,731 37.38 0.4967
2024-08-02 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,690 191 7.64 1,261 20.69 0.3943
2024-04-18 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,499 179 7.72 1,045 10.71 0.3460
2024-02-05 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,320 859 58.80 944 85.63 0.3443
2023-10-30 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,461 42 2.96 508 1.80 0.2087
2023-07-18 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,419 14 1.00 499 12.90 0.2122
2023-05-04 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,405 12 0.86 443 9.95 0.2084
2023-02-13 2022-12-31 13F Vertex Pharmaceuticals Equity 92532F100 1,393 -14 -1.00 402 -1.23 0.1991
2022-11-14 2022-09-30 13F Vertex Pharmaceuticals Equity 92532F100 1,407 23 1.66 407 4.36 0.2167
2022-08-12 2022-06-30 13F Vertex Pharmaceuticals Equity 92532F100 1,384 -331 -19.30 390 -12.95 0.2098
2022-05-16 2022-03-31 13F Vertex Pharmaceuticals Equity 92532F100 1,715 108 6.72 448 26.91 0.2293
2022-02-15 2021-12-31 13F Vertex Pharmaceuticals Equity 92532F100 1,607 292 22.21 353 47.70 0.1867
2021-11-15 2021-09-30 13F Vertex Pharmaceuticals Equity 92532F100 1,315 1,315 239 0.1401
2021-05-17 2021-03-31 13F Vertex Pharmaceuticals Equity 92532F100 0 -1,399 -100.00 0 -100.00
2021-02-12 2020-12-31 13F Vertex Pharmaceuticals Equity 92532F100 1,399 1,399 330 0.2435
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.