Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionLegal & General Group Plc
Latest Disclosed Ownership1,955,764 shares
Latest Disclosed Value $ 873,326,855
Legal & General Group Plc reports 0.73% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Legal & General Group Plc filed a 13F-HR form disclosing ownership of 1,955,764 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $873,326,857 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 1,970,105 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -0.73% during the quarter. The current value of the position is $873,894,028 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,955,764 -14,341 -0.73 873,327 -2.22 0.2020
2026-02-09 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,970,105 17,808 0.91 893,167 16.82 0.1981
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,952,297 62,520 3.31 764,598 -9.12 0.1715
2025-08-12 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,889,777 -4,392 -0.23 841,329 -8.39 0.2088
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,894,169 10,016 0.53 918,331 21.03 0.2501
2025-02-13 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,884,153 -21,159 -1.11 758,748 -14.37 0.2008
2025-02-28 2024-09-30 13F/A-2 VERTEX PHARMACEUTICALS COM 92532F100 1,905,312 -67,063 -3.40 886,122 -4.15 0.2331
2024-11-14 2024-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 2,303,797 -118,880 1,071,449 0.2233
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,303,797 -118,880 1,071,449 0.1127
2025-05-29 2024-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,972,375 -53,291 -2.63 924,490 9.18 0.2612
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,422,677 29,104 1,135,556 0.2542
2025-05-29 2024-03-31 13F/A-2 VERTEX PHARMACEUTICALS COM 92532F100 2,025,666 -35,939 -1.74 846,749 0.94 0.2438
2024-07-01 2024-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 2,393,573 -37,092 1,000,537 0.2336
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,393,573 -37,092 1,000,537 0.1203
2025-05-29 2023-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 2,061,605 21,247 1.04 838,846 18.23 0.2606
2024-02-15 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,430,665 390,307 989,013 0.2538
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,040,358 -88,561 -4.16 709,515 -5.30 0.2475
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,128,919 42,588 2.04 749,187 13.97 0.2437
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,086,331 52,967 2.60 657,338 11.95 0.2351
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,033,364 -104,734 -4.90 587,193 -5.15 0.2254
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,138,098 -62,651 -2.85 619,065 -0.18 0.2419
2022-08-22 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,200,749 143,620 6.98 620,151 15.52 0.2195
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,057,129 158,485 8.35 536,849 28.76 0.1633
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,898,644 -169,690 -8.20 416,943 11.13 0.1261
2021-11-15 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,068,334 119,277 6.12 375,176 -4.53 0.1220
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,949,057 240,660 14.09 392,988 7.05 0.1314
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,708,397 -11,931 -0.69 367,118 -9.71 0.1368
2021-02-12 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,720,328 34,424 2.04 406,582 -11.38 0.1592
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,685,904 47,162 2.88 458,767 -3.57 0.2050
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,638,742 53,940 3.40 475,743 26.22 0.2299
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,584,802 66,406 4.37 376,926 13.38 0.2204
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,518,396 58,778 4.03 332,453 24.21 0.1584
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,459,618 8,308 0.57 267,664 0.26 0.1440
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,451,310 297,731 25.81 266,968 39.66 0.1524
2019-02-15 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,153,579 79,216 7.37 191,159 -7.69 0.1481
2018-11-20 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,074,363 20,630 1.96 207,073 15.62 0.1482
2018-08-10 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,053,733 -43,434 -3.96 179,092 0.15 0.1382
2018-05-17 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,097,167 -53,915 -4.68 178,816 3.66 0.1364
2018-02-13 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,151,082 -26,186 -2.22 172,501 -3.63 0.1248
2017-11-09 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,177,268 36,305 3.18 178,992 21.73 0.1346
2017-08-03 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,140,963 53,020 4.87 147,036 23.59 0.1188
2017-05-12 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,087,943 39,469 3.76 118,966 54.02 0.1010
2017-02-13 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,048,474 10,839 1.04 77,241 -14.64 0.0720
2016-10-12 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,037,635 10,690 1.04 90,492 2.44 0.0917
2016-08-16 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,026,945 50,584 5.18 88,338 13.82 0.0931
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 976,361 -81 -0.01 77,611 -36.83 0.0859
2016-02-16 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 976,442 7,091 0.73 122,865 21.71 0.1388
2015-11-13 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 969,351 33,959 3.63 100,948 -12.60 0.1231
2015-07-31 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 935,392 21,679 2.37 115,503 7.16 0.1357
2015-05-14 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 913,713 -1,536 -0.17 107,790 -0.87 0.1288
2015-02-20 2014-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 915,249 -21,681 -2.31 108,732 3.33 0.1279
2015-02-17 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 915,249 -21,681 108,732 0.1339
2014-11-14 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 936,930 -52,935 -5.35 105,227 12.28 0.1262
2014-08-13 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 989,865 23,257 2.41 93,720 37.10 0.1092
2014-05-14 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 966,608 -4,721 -0.49 68,358 -5.28 0.0830
2014-02-07 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 971,329 35,123 3.75 72,170 1.67 0.0873
2013-11-12 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 936,206 64,367 7.38 70,983 1.94 0.0935
2013-08-01 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 871,839 871,839 69,634 0.0962
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.