Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionLazard Asset Management Llc
Latest Disclosed Ownership213,131 shares
Latest Disclosed Value $ 95,171,606
Lazard Asset Management Llc reports 7.13% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Lazard Asset Management Llc filed a 13F-HR form disclosing ownership of 213,131 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $95,171,517 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 198,950 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 7.13% during the quarter. The current value of the position is $95,233,325 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 213,131 14,181 7.13 95,172 5.52 0.0816
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 198,950 -345,873 -63.48 90,196 -57.73 0.1528
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 544,823 64,513 13.43 213,374 100,075.59 0.2873
2025-08-14 2025-06-30 13F VERTEX PHARMACE Common Stock 92532F100 480,310 -52,287 -9.82 214 -17.44 0.2943
2025-05-15 2025-03-31 13F VERTEX PHARMACE Common Stock 92532F100 532,597 6,478 1.23 258 22.27 0.3965
2025-02-14 2024-12-31 13F VERTEX PHARMACE Common Stock 92532F100 526,119 518,132 6,487.19 212 6,933.33 0.3099
2024-11-14 2024-09-30 13F VERTEX PHARMACE Common Stock 92532F100 7,987 -114,469 -93.48 4 -94.74 0.0050
2024-08-14 2024-06-30 13F VERTEX PHARMACE Common Stock 92532F100 122,456 -1,427 -1.15 57 11.76 0.0720
2024-07-09 2024-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 123,883 4,094 3.42 52 6.25 0.0629
2024-05-14 2024-03-31 13F VERTEX PHARMACE Common Stock 92532F100 123,883 4,094 52 0.0628
2024-02-14 2023-12-31 13F VERTEX PHARMACE Common Stock 92532F100 119,789 833 0.70 49 17.07 0.0617
2023-11-14 2023-09-30 13F VERTEX PHARMACE Common Stock 92532F100 118,956 -760 -0.63 41 -2.38 0.0563
2023-08-15 2023-06-30 13F VERTEX PHARMACE Common Stock 92532F100 119,716 -7,814 -6.13 42 5.00 0.0519
2023-05-15 2023-03-31 13F VERTEX PHARMACE Common Stock 92532F100 127,530 -14,911 -10.47 40 -99.90 0.0527
2023-02-15 2022-12-31 13F VERTEX PHARMACE Common Stock 92532F100 142,441 -481,400 -77.17 41,133 -77.23 0.0567
2022-11-14 2022-09-30 13F VERTEX PHARMACE Common Stock 92532F100 623,841 -240,065 -27.79 180,625 -25.80 0.2639
2022-08-09 2022-06-30 13F VERTEX PHARMACE Common Stock 92532F100 863,906 -33,936 -3.78 243,438 3.90 0.3292
2022-05-13 2022-03-31 13F VERTEX PHARMACE Common Stock 92532F100 897,842 -17,878 -1.95 234,308 16.52 0.2715
2022-02-09 2021-12-31 13F VERTEX PHARMACE Common Stock 92532F100 915,720 749,784 451.85 201,090 568.12 0.2140
2021-11-15 2021-09-30 13F VERTEX PHARMACE Common Stock 92532F100 165,936 24,195 17.07 30,098 5.32 0.0340
2021-08-12 2021-06-30 13F VERTEX PHARMACE Common Stock 92532F100 141,741 25,856 22.31 28,577 14.76 0.0321
2021-05-14 2021-03-31 13F VERTEX PHARMACE Common Stock 92532F100 115,885 -16,224 -12.28 24,902 -20.24 0.0302
2021-02-11 2020-12-31 13F VERTEX PHARMACE Common Stock 92532F100 132,109 -74,073 -35.93 31,221 -44.35 0.0395
2020-11-13 2020-09-30 13F VERTEX PHARMACE Common Stock 92532F100 206,182 5,959 2.98 56,105 -3.48 0.0789
2020-08-13 2020-06-30 13F VERTEX PHARMACE Common Stock 92532F100 200,223 141,600 241.54 58,125 316.73 0.0893
2020-05-14 2020-03-31 13F VERTEX PHARMACE Common Stock 92532F100 58,623 3,264 5.90 13,948 15.08 0.0256
2020-02-13 2019-12-31 13F VERTEX PHARMACE Common Stock 92532F100 55,359 1,027 1.89 12,120 31.68 0.0173
2019-11-14 2019-09-30 13F VERTEX PHARMACE Common Stock 92532F100 54,332 -24,198 -30.81 9,204 -36.08 0.0151
2019-08-14 2019-06-30 13F VERTEX PHARMACE Common Stock 92532F100 78,530 -7,697 -8.93 14,400 -9.21 0.0233
2019-08-28 2019-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 86,227 53,177 160.90 15,861 189.65 0.0259
2019-05-13 2019-03-31 13F VERTEX PHARMACE Common Stock 92532F100 86,227 53,177 15,861
2019-08-28 2018-12-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 33,050 -5,937 -15.23 5,476 -27.12 0.0101
2019-02-13 2018-12-31 13F VERTEX PHARMACE Common Stock 92532F100 33,050 -5,937 5,476
2019-08-30 2018-09-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 38,987 7,252 22.85 7,514 39.33 0.0122
2018-11-13 2018-09-30 13F VERTEX PHARMACE Common Stock 92532F100 38,987 7,252 7,514
2019-08-30 2018-06-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 31,735 -127,772 -80.10 5,393 -79.25 0.0094
2018-08-13 2018-06-30 13F VERTEX PHARMACE Common Stock 92532F100 31,735 -127,772 5,393
2019-08-28 2018-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 159,507 -14,479 -8.32 25,996 -0.30 0.0444
2018-05-14 2018-03-31 13F VERTEX PHARMACE Common Stock 92532F100 159,507 -14,479 25,996
2019-08-28 2017-12-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 173,986 564 0.33 26,073 -1.12 0.0446
2018-02-13 2017-12-31 13F VERTEX PHARMACE Common Stock 92532F100 173,986 564 26,073
2019-08-19 2017-09-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 173,422 -27,745 -13.79 26,367 1.71 0.0477
2017-11-13 2017-09-30 13F VERTEX PHARMACE Common Stock 92532F100 173,422 -27,745 26,367
2019-08-19 2017-06-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 201,167 -254,906 -55.89 25,924 -48.02 0.0488
2017-08-11 2017-06-30 13F VERTEX PHARMACE Common Stock 92532F100 201,167 -254,906 25,924
2019-08-13 2017-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 456,073 -269,331 -37.13 49,871 -6.68 0.0941
2017-05-12 2017-03-31 13F VERTEX PHARMACE Common Stock 92532F100 456,073 -258,081 49,871
2019-07-30 2016-12-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 725,404 -472,069 -39.42 53,440 -48.83 0.1090
2017-02-13 2016-12-31 13F VERTEX PHARMACE Common Stock 92532F100 714,154 -467,273 52,611
2019-08-07 2016-09-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 1,197,473 -68,285 -5.39 104,429 -4.09 0.2075
2016-11-14 2016-09-30 13F VERTEX PHARMACE Common Stock 92532F100 1,181,427 -67,750 103,030
2019-07-29 2016-06-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 1,265,758 283,415 28.85 108,879 39.44 0.2297
2016-08-15 2016-06-30 13F VERTEX PHARMACE Common Stock 92532F100 1,249,177 266,834 107,453
2019-07-25 2016-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 982,343 196,933 25.07 78,085 -20.99 0.1703
2016-05-12 2016-03-31 13F VERTEX PHARMACE Common Stock 92532F100 960,230 174,820 76,327
2019-07-24 2015-12-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 785,410 -462,435 -37.06 98,826 -23.95 0.2261
2016-02-12 2015-12-31 13F VERTEX PHARMACE Common Stock 92532F100 779,841 -468,004 98,126
2019-07-15 2015-09-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 1,247,845 -683,511 -35.39 129,949 -45.51 0.3107
2015-11-13 2015-09-30 13F VERTEX PHARMACE Common Stock 92532F100 1,216,329 -715,027 126,667
2019-07-08 2015-06-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 1,931,356 -154,185 -7.39 238,482 -3.07 0.4999
2015-08-13 2015-06-30 13F VERTEX PHARMACE Common Stock 92532F100 1,871,784 -213,757 231,126
2015-06-09 2015-03-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 2,085,541 -249,418 -10.68 246,029 -11.31 0.5303
2015-05-15 2015-03-31 13F VERTEX PHARMACE Common Stock 92532F100 2,085,541 246,029
2019-08-29 2014-12-31 13F/A-3 VERTEX PHARMACE Common Stock 92532F100 2,334,959 -189,573 -7.51 277,391 -2.16 0.5924
2015-05-20 2014-12-31 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 2,174,007 -160,952 258,271 0.4973
2015-06-09 2014-12-31 13F/A-2 VERTEX PHARMACE Common Stock 92532F100 2,248,217 74,210 267,086 0.6095
2015-02-12 2014-12-31 13F VERTEX PHARMACE Common Stock 92532F100 2,334,969 277,392
2014-11-07 2014-09-30 13F VERTEX PHARMACE Common Stock 92532F100 2,524,532 -102,657 -3.91 283,529 13.99 0.6088
2014-08-12 2014-06-30 13F VERTEX PHARMACE Common Stock 92532F100 2,627,189 -129,546 -4.70 248,740 27.59 0.5199
2014-05-12 2014-03-31 13F VERTEX PHARMACE Common Stock 92532F100 2,756,735 -585,666 -17.52 194,955 -21.50 0.4355
2014-02-14 2013-12-31 13F VERTEX PHARMACE Common Stock 92532F100 3,342,401 -46,903 -1.38 248,339 -3.36 0.5512
2014-01-13 2013-09-30 13F/A-1 VERTEX PHARMACE Common Stock 92532F100 3,389,304 -260,763 -7.14 256,976 -11.85 0.6098
2013-11-13 2013-09-30 13F VERTEX PHARMACE Common Stock 92532F100 3,457,290 262,130
2013-08-13 2013-06-30 13F VERTEX PHARMACE Common Stock 92532F100 3,650,067 3,650,067 291,529 0.6909
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.